Clinical trials: Carotid Disease
Carotid Stenosis
Insulin Resistance in Patients After Carotid Revascularization
The main purpose of this study is to study the phenomenon of insulin resistance in patients after carotid revascularization surgery through population-based, randomized, double-blind, placebo-controlled trial.
- Trial name
- NCT03419767
- Testing
- Melatonin, blank
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking Union Medical College Hospital
Type 2 Diabetes, A1C Variability
Is Carotid Intima-media Thickness Affected by A1C Variability?
This study was conducted to evaluate the effect of A1C variability on the progression of carotid artery intima-media thickness in type 2 diabetic patients.
- Trial name
- NCT00842972
- Sponsor
- Yonsei University
General Anesthesia
Ability of Carotid Sonography and Inferior Vena Cava Sonography for the Prediction of Post-induction Hypotension in Hypertensive Patients
Hypertensive patients have more hemodynamic instability during general anesthesia than do patients with NORMOTENSION. In this study, the investigators evaluated the usefulness of carotid ultrasound and inferior vena cervical…
- Trial name
- NCT03986112
- Testing
- carotid sonography and inferior vena cava sonography
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Yonsei University
Carotid Artery Stenosis, Carotid Artery Diseases
Study on the Trans-Carotid Artery Occlusion Shunt System Combined With Introducer Sets
The objective of the study is to evaluate the Safety and Efficacy of the Trans-Carotid Artery Occlusion Shunt System Combined with Introducer Sets for Cerebral Protection During Carotid Angioplasty
- Trial name
- NCT06959628
- Testing
- Trans-Carotid Artery Occlusion Shunt System Combined with Introducer Sets
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Shenzhen Wecan Medical Technology Co.,Ltd
Coronary Artery Disease, Coronary Heart Disease
Safety and Efficacy Study Using ABT-335 (Investigational Drug) in Combination With Atorvastatin, to Study the Effects on Thickening of the Blood Vessel Wall in Patients With Abnormal Lipid (Fat) Levels in the Blood
The primary purpose of this study is to test the effect and safety of once daily ABT-335 on the thickness of the lining of the carotid artery (a blood vessel to the brain) in patients with abnormal blood lipids who have optimal…
- Conditions
- Coronary Artery Disease, Coronary Heart Disease, Dyslipidemia
- Trial name
- FIRST (NCT00616772)
- Testing
- ABT-335, Atorvastatin
- Where
- 124 sites in United States
- Volunteers
- 682 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Hypertension,Essential
First-In-Human Study Evaluating a Novel Catheter Device in Subjects With Treatment-Resistant Hypertension
The carotid body is located at the bifurcation of the internal and external carotid arteries. It is a chemoreceptor that plays a role in the sympathetic nervous system and in the development and maintenance of hypertension.
- Trial name
- NCT03314012
- Testing
- Catheter-Based Carotid Body Ablation
- Where
- 7 sites in Australia, Czechia and 1 more
- Volunteers
- 39 people
- Sponsor
- Cibiem, Inc.
Carotid Stenosis
Carotid Region Calcifications and Orthopantomogram
Observational study.
- Trial name
- ADCACO (NCT03936881)
- Where
- France
- Volunteers
- 401 people
- Sponsor
- Rennes University Hospital
Kidney Failure, Renal Dialysis
Comparison of Bovine Carotid Artery and Expanded Polytetrafluoroethylene (ePTFE) for Permanent Hemodialysis Access
The investigators did a randomized control trial comparing bovine carotid artery grafts with ePTFE grafts for patients that need hemodialysis access.
- Trial name
- NCT01021839
- Testing
- Grafts placement
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Massachusetts General Hospital
Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction
Clinical Impact of Using IMPROVE to Select Patients for Carotid Revascularisation
Narrowing of the carotid artery due to atherosclerosis with an unstable plaque can cause a stroke. Patients with carotid artery disease who have had a TIA or minor stroke and are at high risk of another stroke are often treated…
- Conditions
- Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction, Stroke Ischemic, Atheroscleroses
- Trial name
- IMPROVE (NCT07556887)
- Testing
- IMPROVE Risk Model
- Where
- 10 sites in Netherlands
- Volunteers
- 613 people
- Sponsor
- Maastricht University Medical Center
Carotid Stenosis, Carotid Artery Plaque
CARotid Mri of Atherosclerosis
In the entire world most people die from cardiovascular disease. Death is primarily from myocardial infarction (MI) and stroke which are most often caused by rupture of atherosclerotic plaques. Patients with high-grade, i.e.
- Conditions
- Carotid Stenosis, Carotid Artery Plaque, Carotid Atherosclerosis
- Trial name
- CARMA (NCT04835571)
- Testing
- Optimization of cardiovascular risk management
- Volunteers
- 52 people
- Sponsor
- Linkoeping University
Stroke, Stenosis
Abciximab for Prevention of Stroke Recurrence Before Endarterectomy in Symptomatic Carotid Stenosis
The purpose of the present prospective, randomized, double-blind, double dummy controlled multicenter pilot study is to investigate whether abciximab, compared with aspirin, is able to reduce the rate of recurrent ischemic…
- Trial name
- NCT00126139
- Testing
- Abciximab
- Where
- 5 sites in Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Stroke
Balloon Guide Catheter to Optimize Outcomes in Stroke Thrombectomy of the Internal Carotid Artery
To investigate whether using balloon guide catheter with flow arrest during mechanical thrombectomy, compared to non-flow arrest, improves the rate of first pass expanded Thrombolysis in Cerebral Infarction score (eTICI 2c-3)…
- Trial name
- NCT07192029
- Testing
- Balloon guide catheter combined with conventional thrombectomy treatment, Standard guide catheter or neurovascular sheath combined with conventional thrombectomy treatment
- Where
- 3 sites in China
- Volunteers
- 364 people
- Sponsor
- Xuanwu Hospital, Beijing
Carotid Stenosis
Noninvasive Evaluation for Carotid Artery Stenosis: The Carotid Stenotic Scan
The purpose of this study is to determine the accuracy of a new non-invasive device, the Carotid Stenotic Scan (CSS), to check for stenosis of the internal carotid artery (ICA) as compared to a carotid duplex ultrasound study.
- Trial name
- CSS (NCT04057183)
- Testing
- Carotid Stenotic Scan
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Phillip J Bendick
Cardiac Arrest (CA), Cardiopulmonary Resuscitation
RescueDoppler- a Disruptive Ultrasound Solution for Improved Outcome After Cardiac Arrest.
RescueDoppler is an innovative, hands-free Doppler system designed for continuous monitoring of blood flow in the carotid artery, distinguishing between the presence and absence of a pulse.
- Conditions
- Cardiac Arrest (CA), Cardiopulmonary Resuscitation, Doppler Ultrasound
- Trial name
- RescueDoppler (NCT06599073)
- Testing
- RescueDoppler, Rescue
- Where
- 8 sites in Norway, Sweden
- Volunteers
- 285 people
- Sponsor
- Norwegian University of Science and Technology
Coronary Heart Disease
Trial of Lycopene/Ateronon for Secondary Prevention of Coronary Heart Disease
The purpose of this study is to determine whether Ateronon, a nutritional supplement that contains lycopene from tomatoes has a favorable effect on carotid atherosclerosis, lipid levels, and other biomarkers of coronary heart…
- Trial name
- NCT00939237
- Testing
- Ateronon
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- Brigham and Women's Hospital
Cerebrovascular Occlusion, Collateral Blood Circulation
The Impact of NBP on the Collateral Circulation in ICA/M1 Occlusion
Stroke is the first leading cause of death in China, and is responsible for almost 22.4% of deaths. In approximately 80% of cases stroke is ischaemic, i.e.
- Conditions
- Cerebrovascular Occlusion, Collateral Blood Circulation, Anterior Cerebral Circulation Infarction
- Trial name
- INCIMO (NCT02594995)
- Testing
- NBP
- Where
- China
- Volunteers
- 311 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Hypertriglyceridemia, Carotid Atherosclerotic Plaques
A Trial to Evaluate the Efficacy and Safety of DR10624 in Patients With Hypertriglyceridemia and Carotid Atherosclerotic Plaque
This is a researcher-initiated study to evaluate the effect of DR10624 injection on carotid atherosclerotic plaques in patients with hypertriglyceridemia and carotid atherosclerotic plaques.
- Trial name
- NCT07050134
- Testing
- DR10624 Injection；
- Where
- 4 sites in China
- Volunteers
- 40 people
- Sponsor
- Junbo Ge
Carotid Artery Calcification, Periodontal Diseases
Assessment of Carotid Artery Calcifications
The aim of the study was to determine retrospectively the presence of carotid artery calcification (CAC) detected on digital panoramic radiographs (DPRs) and correlate the finding of such calcifications with gender, smoking…
- Trial name
- NCT04017078
- Testing
- diagnosis of carotid artery calcification on digital panoramic radiograph
- Where
- Turkey (Türkiye)
- Volunteers
- 1,101 people
- Sponsor
- Baskent University
Chronic Kidney Disease Requiring Chronic Dialysis
Intradialytic Pedalling Exercise and Vascular Hemodynamic Parameters Among Prevalent Hemodialysis Population
The purpose of this pilot study is to evaluate 1) the effect of intradialytic pedaling exercise on arterial stiffness and other arterial hemodynamic parameters over 4 months, and 2) the longer-term effect of pedaling on arterial…
- Trial name
- NCT03027778
- Testing
- Exercise
- Volunteers
- 32 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Stroke, Ischemic Attack, Transient
Carotid Plaque Imaging in Acute Stroke
The purpose of this study is to determine the frequency, characteristics, and consequences of vulnerable carotid artery plaques ipsilateral to an acute ischemic stroke or TIA in the territory of the internal carotid artery.
- Trial name
- CAPIAS (NCT01284933)
- Where
- 4 sites in Germany
- Volunteers
- 234 people
- Sponsor
- Ludwig-Maximilians - University of Munich
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