Clinical trials: Carotid Disease
Dyslipidaemias, Carotid Artery Stenoses
Improved Medication and Care to Achieve Lipid Targets After Carotid Surgery
The goal of this clinical trial is to find out if patients who receive extra support stay on their cholesterol-lowering therapy and therefore have lower cholesterol levels after 4 months.
- Trial name
- IMACS (NCT07064135)
- Testing
- Prompt Medication Adjustment and Intensive Follow-up, Standard Care
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Barmherzige Brüder Linz
Atherosclerosis
A Trial of the Safety and Efficacy of K-604 for the Treatment of Atherosclerosis
The purpose of this study is to evaluate the safety and efficacy of K-604 for the treatment of atherosclerosis.
- Trial name
- NCT00851500
- Testing
- K-604
- Where
- 19 sites in United States
- Volunteers
- 210 people
- Sponsor
- Kowa Research Institute, Inc.
Asymptomatic Carotid Artery Stenosis
" Endarterectomy Combined With Optimal Medical Therapy (OMT) vs OMT Alone in Patients With Asymptomatic Severe Atherosclerotic Carotid Artery Stenosis at Higher-than-average Risk of Ipsilateral Stroke "
The purpose of this study is to determine whether carotid surgery combined with optimal medical therapy improves long-term survival free of ipsilateral stroke in patients with asymptomatic carotid stenosis at higher-than-average…
- Trial name
- ACTRIS (NCT02841098)
- Testing
- Carotid endarterectomy (CEA) combined with optimal medical therapy (OMT), Optimal medical therapy alone
- Where
- 23 sites in France
- Volunteers
- 43 people
- Sponsor
- Centre Hospitalier St Anne
Atherosclerosis, Cardiovascular Diseases
Epidemiology of Carotid Artery Atherosclerosis in Youth
To examine the relationship of risk factors measured in childhood to intimal medial thickness (IMT) in early adulthood and to examine familial factors which may be related to increased IMT, a measure of atherosclerosis.
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Heart Diseases, Carotid Artery Diseases
- Trial name
- NCT00005397
- Volunteers
- 1,360 people
- Sponsor
- Patricia H Davis
Transient Ischemic Attack, Thromboembolic Stroke
Carotid Artery Revascularization Using the Boston Scientific EPI Filter Wire EZ™ and the EndoTex™ NexStent™
The primary objective of this study is to demonstrate the safety of the NexStent for treatment of carotid artery lesions undergoing stenting with adjunctive use of the FilterWire distal embolic protection device.
- Conditions
- Transient Ischemic Attack, Thromboembolic Stroke, Stroke Prevention
- Trial name
- CABERNET (NCT00600327)
- Testing
- EndoTex™ NexStent™, Filter Wire EZ™
- Where
- 19 sites in United States, Argentina and 1 more
- Volunteers
- 488 people
- Sponsor
- Boston Scientific Corporation
Aortic Aneurysm, Abdominal, Carotid Atherosclerosis
Targeted PET/CT and PET/MRI Imaging of Vascular Inflammation
Stroke and abdominal aortic aneurysms (AAAs) are common and highly lethal vascular diseases. Angiogenesis and infiltration of inflammatory cells such as macrophages may cause stroke and AAAs.
- Trial name
- NCT02995642
- Testing
- 18F-FPPRGD2, Positron emission tomography, Computed tomography
- Where
- United States
- Sponsor
- Stanford University
Stroke, Occlusion Carotid
Endovascular Revascularization of Symptomatic Chronically Occluded Internal Carotid Artery
This is a phase 2 randomized single-center open label clinical trial with randomization of 1:1 to either best medical management vs. best medical management and endovascular revascularization of chronically occluded ICA (COICA).
- Trial name
- NCT03176420
- Testing
- angioplasty and stenting of occluded cervical ICA
- Sponsor
- University of Iowa
Protein; Disease, Carotid Artery Plaque
The Proteomic Study and Early Intervention Study of Carotid Unstable Plaque
A study on the prediction model of carotid unstable plaque protein and its early intervention. Protein antibody chip was used to detect the remaining biological samples, and patients with carotid artery unstable plaque with…
- Conditions
- Protein; Disease, Carotid Artery Plaque, Traditional Chinese Medicine
- Trial name
- NCT05622877
- Testing
- Qushi Formula, Zhu's Wenban Formula, Basic treatment
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Carotid Artery Disease, Carotid Artery Stenosis
Effect of Raised CBF During CEA on Cognition in DM Patients
The purpose of this study is to determine if we can reduce the incidence of cognitive dysfunction - difficulty in performing certain pencil-paper, memory, finger dexterity and thinking type of tasks called neuropsychometric tests…
- Conditions
- Carotid Artery Disease, Carotid Artery Stenosis, Diabetes, Cognitive Dysfunction
- Trial name
- NCT00597545
- Testing
- Carotid endarterectomy, Shunt
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Columbia University
Chronic Cerebral Ischemia, Moyamoya Disease
Application of Extended Reality (XR)-Assisted Computed Tomography (CT)-Guided Localization in Extracranial-intracranial (EC-IC) Bypass Surgery
This study will evaluate the application of a metaverse-based surgical simulation platform in extracranial-intracranial (EC-IC) bypass surgery.
- Conditions
- Chronic Cerebral Ischemia, Moyamoya Disease, Bypass Surgery, Augmented Reality
- Trial name
- NCT07711457
- Testing
- NTU OpVerse surgical simulation platform
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Acute Kidney Injury
Carotid Doppler and IVC Measurements for Volume Guided Management in Acute Kidney Injury Patients
1. Evaluate Inferior Vena Cava Indices (Diameters , IVC-CI)\&carotid doppler measurements (corrected Carotid Flow Time ,Carotid Blood Flow ,Carotid Artery Peak Velocity Variations) as Non-Invasive Technique for volume guided…
- Trial name
- NCT05938049
- Testing
- IVC ultrasound & Carotid doppler
- Volunteers
- 60 people
- Sponsor
- Assiut University
Erectile Dysfunction Due to Arterial Disease
Carotid Artery Intima Media Thickness Can Predict the Response to Phosphodiesterase 5 Inhibitors in the Patients With Moderate Erectile Dysfunction
The aim of the present study was to examine the relationship between degrees of erectile dysfunction and carotid artery intima media thickness (CIMT) and its effect on the medical treatment of this disease.
- Trial name
- NCT05679999
- Testing
- CIMT (Carotid artery intima media thickness measurement)
- Where
- Turkey (Türkiye)
- Volunteers
- 181 people
- Sponsor
- Bursa City Hospital
Atherosclerosis of Artery, Carotid Endarterectomy
Associations of Carotid Plaque Characteristics With Brain Perfusion and Cognitive Function in Patients Undergoing CEA
Stroke is one of the leading causes of death and disability-adjusted life-years worldwide. Carotid high-risk atherosclerotic plaques are considered to be one of the major sources of ischemic stroke.
- Trial name
- NCT04955015
- Testing
- carotid endarterectomy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Hypertension, Whole Body Vibration
Effects of Whole Body Vibration and Resistance Exercise on Carotis Intima Media and Muscle Architecture in Hypertension
Exercise is of great importance in the treatment of hypertension, which is expressed as a very serious disease, the prevalence of which is increasing day by day in the world and can cause many complications that are common in…
- Conditions
- Hypertension, Whole Body Vibration, Muscle Architecture, Carotid Intima Media Thickness
- Trial name
- NCT05775835
- Testing
- Whole body vibration and strengthening exercise, Whole body vibration exercise, Strengthening exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Suleyman Demirel University
Hypertension
Chemical Block and Electrical Stimulation of the Carotid Body to Treat Refractory Hypertension
High blood pressure, also referred to as hypertension, affects about 65 million people in the United States alone. Approximately 25 percent of people with hypertension cannot control their high blood pressure, despite the use of…
- Trial name
- NCT02519868
- Testing
- Electrical block, Chemical block
- Where
- Switzerland
- Sponsor
- Eric Albrecht
Atherosclerosis of Artery, Coronary Artery Disease
Effects of aSPIrin Versus Aspirin Plus Low-dose RIvaroxaban on Carotid aTherosclerotic Plaque Inflammation
Primary Study Objective : To compare the effects of low-dose rivaroxaban plus aspirin versus aspirin on atherosclerotic plaque inflammation using serial FDG Positron Emission Tomography/Computed Tomography(PET-CT) imaging of…
- Conditions
- Atherosclerosis of Artery, Coronary Artery Disease, Peripheral Arterial Disease, Carotid Stenosis
- Trial name
- SPIRIT (NCT05797376)
- Testing
- Rivaroxaban 2.5mg
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Asan Medical Center
Carotid Atherosclerosis
Sonodynamic Therapy in the Treatment of Carotid Atherosclerosis
Sonodynamic therapy (SDT) is a new treatment for carotid atherosclerotic plaque. The purpose of this study is to evaluate the safety and initial effectiveness of this technique.
- Trial name
- SMART-C (NCT03871725)
- Testing
- Sonodynamic therapy (SDT)
- Where
- China
- Volunteers
- 12 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Abnormalities, Radiation-Induced, Atherosclerosis
Radiation Induced Atherosclerosis in Breast Cancer Patients
Radiation induced accelerated atherosclerosis is a well known entity that occurs in different regions, according to the therapy delivered.It is usually begins to be clinically evident several years after the radiation incident…
- Conditions
- Abnormalities, Radiation-Induced, Atherosclerosis, Breast Cancer
- Trial name
- NCT00388713
- Testing
- carotid intima-media thickening ultrasound
- Where
- Israel
- Volunteers
- 350 people
- Sponsor
- Hadassah Medical Organization
Carotid Atherosclerosis, Regional Anesthesia Morbidity
Anterior Ultrasound-guided Cervical Plexus Block for Carotid Endarterectomy
The aim of this study is to describe technique, efficiency, safety and satisfaction of ultrasound guided intermediate cervical plexus block for carotid endarterectomy.
- Trial name
- NCT01640613
- Where
- France
- Volunteers
- 116 people
- Sponsor
- Hôpital Edouard Herriot
Carotid Artery Injuries, Traumatic Injury
Use of 81 vs 325mg of ASA in Treatment of BCVI
Blunt cerebrovascular injury (BCVI), or injury to the carotid and vertebral arteries, occurs in 1-3% of blunt traumas, often as a result of injury to the head, neck, or chest.
- Conditions
- Carotid Artery Injuries, Traumatic Injury, Vertebral Artery Injury
- Trial name
- NCT06383650
- Testing
- Acetylsalicylic Acid
- Volunteers
- 40 people
- Sponsor
- London Health Sciences Centre
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