Clinical trials: Carotid Disease
Solid Malignancy Located in the Head and Neck, Cancer
Study of 68GaNOTA-Anti-MMR-VHH2 in Oncological Lesions, Cardiovascular Atherosclerosis, Syndrome With Abnormal Immune Activation and sarcoïdosis
Phase II study to evaluate the clinical potential of 68GaNOTA-anti-MMR-VHH2 for in vivo imaging of Macrophage Mannose Receptor (MMR)-expressing Macrophages by means of Positron Emission Tomography (PET) in patients with…
- Conditions
- Solid Malignancy Located in the Head and Neck, Cancer, Carotid Stenosis, Atherosclerosis of Artery
- Trial name
- MITRAS (NCT04758650)
- Testing
- 68GaNOTA-Anti-MMR-VHH2
- Where
- Belgium
- Volunteers
- 29 people
- Sponsor
- Universitair Ziekenhuis Brussel
Cardiovascular Diseases, Heart Diseases
Epidemiology of Cardiovascular Risk Factors in Women (Healthy Women Study)
To determine cardiovascular risk factors and the change in risk factors during and following the menopause.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Depression, Carotid Artery Diseases
- Trial name
- NCT00005160
- Volunteers
- 532 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Atherosclerosis
Effect of Short Term Atorvastatin Treatment,80mg/Day on Early Regression of Carotid Artery Atherosclerotic Lesions
Atherosclerosis is a disease in which the blood vessels become blocked by plaques (consisting of fat, calcification, and fibrous tissue), reducing blood flow to vital organs and tissues.Blockage of the carotid arteries in the…
- Trial name
- DCAT (NCT00640744)
- Testing
- Atorvastatin
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Baylor College of Medicine
Carotid Artery Stenosis, Carotid Atherosclerosis
Photon-Counting CT Versus Conventional CT for Carotid Plaque Assessment in Patients With Carotid Artery Stenosis
This prospective observational study aims to compare photon-counting detector computed tomography angiography (PCD-CTA) with conventional energy-integrating detector computed tomography angiography (EID-CTA) for the assessment of…
- Conditions
- Carotid Artery Stenosis, Carotid Atherosclerosis, Carotid Atherosclerotic Plaque
- Trial name
- NCT07762664
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chinese PLA General Hospital
Diabetes Mellitus, Type 1 Diabetes, Cardiovascular Diseases (CVD)
Relationship Between Insulin Dose and Complications in Type 1 Diabetes
The goal of this observational study is to better understand how the amount of insulin people with type 1 diabetes are using relates to blood glucose control and the risk of complications.
- Conditions
- Diabetes Mellitus, Type 1 Diabetes, Cardiovascular Diseases (CVD), Severe Albuminuria, Estimated Glomerular Filtration Rate (eGFR)
- Trial name
- iDose-EDC (NCT07911033)
- Testing
- Routine/prescribed exogenous insulin dose
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Rachel Miller
Coronary Disease
Atherosclerosis in the Coronary and Carotid Arteries
This study will compare changes in atherosclerotic plaque in the coronary arteries (vessels on the surface of the heart that supply blood to the heart) with changes in the carotid arteries (vessels in the neck that supply blood…
- Trial name
- NCT00080587
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Quadrantectomies, Spinal Fusion
Complementary and Alternative Medicine Interventions in Targeting Pain
This Controlled Randomized Clinical Trial aimed at determining the effectiveness of a modified RR intervention in reducing post-operative pain and psychological symptoms in patients undergoing surgery intervention.
- Conditions
- Quadrantectomies, Spinal Fusion, Carotid Stenosis, Abdominal Aortic Aneurysm
- Trial name
- CAMP (NCT04845334)
- Testing
- RR intervention
- Volunteers
- 128 people
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Neurologic Dysfunction
Optic Nerve Sheath Diameter, Carotid Duplex and Transcranial Duplex as a Prognostic Factor
Optic nerve sheath diameter (ONSD) had been proved to be associated with increased intracranial pressure and can be used as one of the prognostic factors in cardiac arrest patients.
- Trial name
- NCT04510363
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Atherosclerosis
Carotid Atherosclerotic Disease Following Childhood Scalp Irradiation
Background: During the first half of the 20th century, scalp irradiation was a standard treatment for induction of epilation in children suffering from Tinea Capitis.
- Trial name
- NCT00590421
- Where
- Israel
- Volunteers
- 295 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Carotid Artery Diseases
Digital Variance Angiography for Contrast Media Dose Reduction in Carotid Artery Stenting
Digital Variance Angiography (DVA) is a new tool in medical imaging with a proven image quality reserve (1, 2). Previous studies have demonstrated the quality reserve of DVA in angiographic studies (1, 2), which allowed us to…
- Trial name
- NCT04792255
- Testing
- Carotid artery stenting with standard contrast media protocol, Carotid artery stenting with reduced contrast media protocol, Carotid Duplex Ultrasound
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- Kinepict Health Ltd.
Carotid Atherosclerosis
Sonodynamic Therapy Manipulates Atherosclerosis Regression Trial on Patients With Carotid Atherosclerotic Plaques
Sonodynamic therapy (SDT) is a new treatment for carotid atherosclerotic plaque. The aim of this study is to assess the safety and efficacy of this technique.
- Trial name
- SMART-C (NCT03382249)
- Testing
- Sonodynamic therapy (SDT), pseudo-SDT
- Where
- China
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Carotid Atherosclerosis, Stroke
Diagnosis and Therapy of Vulnerable Atherosclerotic Plaque
The aim of the present study is to examine the atherosclerotic plaque stability using in vivo and in vitro techniques and to investigate the influence of exercise, anti-diabetic, lipid-lowering and cannabinoids receptor…
- Conditions
- Carotid Atherosclerosis, Stroke, Type 2 Diabetes, Metabolic Syndrome
- Trial name
- NCT00636766
- Testing
- atorvastatin, rimonabant, rosiglitazone
- Where
- Greece
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Carotid Atherosclerosis
Imaging 61CuATSM Uptake in Atherosclerotic Plaque Using PET-CT
The build up of plaque in the wall of the artery supplying blood to the brain poses a risk of stroke when the plaques become unstable and fragile.
- Trial name
- NCT01000181
- Testing
- PET-CT with CuATSM
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- King's College London
Endovascular Carotid Surgery, Preoperative Hypotension
Compared Efficacy and Tolerance of Two Vasopressors Used to Treat Preoperative Hypotension During Carotid Surgery
The effects on brain perfusion of the two currently vasopressors used to treat accidental hypotension occurring during carotid surgery (i.e.
- Trial name
- VP-hTA-XCar (NCT01794273)
- Testing
- ephedrine and phenylephrine
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Cardiovascular Diseases, Hypercholesterolemia
The Combined Portfolio Diet and Exercise Study
The purpose of this study is to determine whether a dietary portfolio of cholesterol-lowering foods (viscous fibres, soy protein, plant sterols and nuts) further enhanced by increased levels of monounsaturated fatty acids (MUFA)…
- Conditions
- Cardiovascular Diseases, Hypercholesterolemia, Type 2 Diabetes, Metabolic Syndrome
- Trial name
- PortfolioEx (NCT02481466)
- Testing
- Portfolio diet and structured exercise, DASH-like diet and structured exercise, Portfolio diet and routine exercise
- Where
- 4 sites in Canada
- Volunteers
- 232 people
- Sponsor
- Unity Health Toronto
Carotid Stenosis
Microembolisation After Carotid Revascularisation
Microembolisation identified on diffusion-weighted magnetic resonance imaging (DW-MRI) is recognized as an important outcome measure for carotid revascularization procedures such as carotid stenting (CAS) or carotid…
- Trial name
- NCT03303430
- Testing
- MRI
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- University Hospital, Geneva
Carotid Stenosis
CorMatrix ECM for Carotid Repair Following Endarterectomy Registry
Assess device performance data from subjects undergoing patch angioplasty of the carotid artery following carotid endarterectomy using the CorMatrix ECM for Carotid Repair.
- Trial name
- NCT01569594
- Testing
- CorMatrix ECM for Carotid Repair
- Where
- 6 sites in United States
- Volunteers
- 230 people
- Sponsor
- Elutia Inc.
Type 2 Diabetes
The Effects of Micronutrients in Combination With Usual Care in Type 2 Diabetes
This study is evaluating the impact of antioxidant supplements on blood sugar control and cardiovascular risk factors in adults over the age of 50 with at 3 months of Type 2 diabetes.
- Trial name
- PMC (NCT01738802)
- Testing
- Anti-oxidant and micronutrient
- Where
- 2 sites in United States
- Volunteers
- 111 people
- Sponsor
- Walter Reed National Military Medical Center
Carotid Stenosis, Carotid Artery Diseases
Cerebral Oximetry During Awake Carotid Endarterectomy
Surgery to remove plaque from the carotid artery in the neck requires the artery to be clamped for a period of time. In some patients this reduces blood flow to the brain enough to cause temporary symptoms, and a temporary…
- Conditions
- Carotid Stenosis, Carotid Artery Diseases, Brain Ischemia, Carotid Endarterectomy
- Trial name
- COACE (NCT07816081)
- Testing
- Masked continuous cerebral oximetry, Standardised awake neurological test, Serial cognitive assessment
- Where
- Vietnam
- Volunteers
- 150 people
- Sponsor
- Nguyen Toan Thang
Carotid Artery Diseases, Carotid Artery Stenosis
Timing Carotid Stent Clinical Study for the Treatment of Carotid Artery Stenosis（Timing Trial）
Evaluate the safety and efficacy of the Timing Carotid Stent for the treatment of carotid artery stenosis in patients.
- Conditions
- Carotid Artery Diseases, Carotid Artery Stenosis, Stroke, Ischemic Stroke
- Trial name
- NCT05574972
- Testing
- Timing Carotid Stent, Carotid Wallstent
- Where
- China
- Volunteers
- 178 people
- Sponsor
- Suzhou Zenith Vascular SciTech Limited