Clinical trials: Carotid Disease
Carotid Stenosis
Differences of the Postoperative Outcome for Carotid Surgery Patients Treated by Either Male or Female Surgeons
This research will focus on the differences of the postoperative outcome for carotid surgery patients treated by either male or female surgeons.
- Trial name
- NCT06485102
- Testing
- Carotid Surgery in patients with symptomatic or asymptomatic stenosis
- Where
- Germany
- Volunteers
- 800 people
- Sponsor
- University Hospital Augsburg
Coronary Artery Disease, Carotid Artery Diseases
Evaluate Carotid Artery Plaque Composition by Magnetic Resonance Imaging in People Receiving Cholesterol Medication
Atherosclerosis is a condition that occurs when fatty deposits build up along the inner walls of arteries. This study will examine the effectiveness of a combination of cholesterol-lowering medications at decreasing the fat…
- Conditions
- Coronary Artery Disease, Carotid Artery Diseases, Atherosclerosis
- Trial name
- CPC (NCT00715273)
- Testing
- Atorvastatin, Niacin, Colesevelam
- Where
- 4 sites in United States
- Volunteers
- 217 people
- Sponsor
- University of Washington
Neurocognitive Disorders, Alzheimer's Disease
Evaluation of the Link Between Carotid Arterial Wall Viscosity and Major Neurocognitive Disorders
The mechanical behavior of conductance arteries is viscoelastic. While the elastic component has been extensively studied, the viscous component has often been neglected for methodological reasons and also because it was…
- Trial name
- VISCOG (NCT07205003)
- Testing
- Assessment of carotid wall viscosity in patients with vascular dementia, Assessment of carotid wall viscosity in patients with Alzheimer's disease, Assessment of carotid wall viscosity in patients not presenting dementia.
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Rouen
Carotid Artery Disease
CARotid plaqUe StabilizatiOn and Regression With Evolocumab.
The CARUSO trial aims at investigating the efficacy of evolocumab in promoting carotid plaque morphological stabilization and regression as compared to traditional lipid lowering therapy (LLT).
- Trial name
- CARUSO (NCT04730973)
- Testing
- Evolocumab, lipid-lowering therapy (LLT)
- Where
- Italy
- Volunteers
- 130 people
- Sponsor
- Azienda Ospedaliera Ordine Mauriziano di Torino
Type 2 Diabetes Mellitus, Carotid Atherosclerosis
Effect of Cilostazol on Carotid Atherosclerosis Estimated by 3D Ultrasound in Patients With Type 2 Diabetes
To investigate the effect of cilostazol compared with aspirin on carotid atherosclerosis in patients with type 2 diabetes mellitus
- Trial name
- NCT03248401
- Testing
- Cilostazol, Aspirin
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Bundang Hospital
Stroke, Plaque, Atherosclerotic
ParisK: Correlation of Imaging Techniques With Histology
The possibility to identify the risk of rupture of a carotid plaque will have tremendous impact in clinical decision making. A vulnerable plaque is considered to have a large lipid rich necrotic core (LRNC), a thin fibrous cap…
- Trial name
- ParisK (NCT01709045)
- Testing
- Magnetic Resonance Imaging (MRI), Dual-Energy Computed Tomography (DECT), Ultrasound
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Maastricht University Medical Center
Effects of High Altitude, Hypoxia
Induced Changes in Ventilatory Responsiveness and Altitude Exposure
The main purpose of this study is to determine if a drug (acetyl-cysteine or ACCY) can increase the amount of oxygen in your body at a high altitude of 11,500 feet.
- Conditions
- Effects of High Altitude, Hypoxia, Inadequate or Impaired Breathing Pattern or Ventilation, Abnormal Blood Oxygen Pressure
- Trial name
- NCT01241513
- Testing
- NAC
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Cerebrovascular Disease, Ischemic Stroke
Florida Cerebrovascular Disease Biorepository and Genomics Center
The purpose of this study is to create a state-wide biorepository and resource center for cerebrovascular diseases in Florida, which will include collecting medical history information and blood from subjects affected by…
- Conditions
- Cerebrovascular Disease, Ischemic Stroke, Transient Ischemic Attack, Intracerebral Hemorrhage
- Trial name
- NCT05491980
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Mayo Clinic
Chronic Cerebral Ischemia, Moyamoya Disease
Application of Extended Reality (XR)-Assisted Computed Tomography (CT)-Guided Localization in Extracranial-intracranial (EC-IC) Bypass Surgery
This study will evaluate the application of a metaverse-based surgical simulation platform in extracranial-intracranial (EC-IC) bypass surgery.
- Conditions
- Chronic Cerebral Ischemia, Moyamoya Disease, Bypass Surgery, Augmented Reality
- Trial name
- NCT07711457
- Testing
- NTU OpVerse surgical simulation platform
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Atherosclerotic Disease, Carotid
Post-Approval Study of the Guidant Carotid Stent Systems and Embolic Protection Systems: CAPTURE
This purpose of this study is to collect data on the FDA-approved ACCULINK(TM) Carotid Stent System and FDA 510(k)-cleared ACCUNET(TM) Embolic Protection System for the treatment of patients with atherosclerotic disease, when…
- Trial name
- NCT00180492
- Testing
- RX ACCULINK(TM) Carotid Stent System and RX ACCUNET(TM) Embolic Protection System
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Abbott Medical Devices
Stroke, Transient Ischemic Attack
Angiogenic Markers in Cerebrovascular Disease (ANFIS)
Intracranial atherosclerosis (ICAS) is the most common cause of stroke worldwide. It carries a worse prognosis than other stroke etiologies, with an annual rate of recurrent stroke and death of 15% despite intensive medical…
- Conditions
- Stroke, Transient Ischemic Attack, Atherosclerosis, Intracranial Arterial Stenosis
- Trial name
- ANFIS (NCT04240119)
- Testing
- According to current clinical care standards
- Volunteers
- 300 people
- Sponsor
- Cedars-Sinai Medical Center
Stroke, Ischemic, Stenosis, Carotid
Impact of Significant Carotid Stenosis on Retinal Perfusion Measured Via Automated Retinal Oximetry
Background: Large vessel carotid stenosis represent significant cause of ischaemic stroke. Indication for surgical revascularisation treatment relies on severity stenosis and clinical symptoms.
- Trial name
- NCT06085612
- Testing
- Automated retinal oximetry
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- University Hospital Olomouc
Rheumatoid Arthritis
Effects of HMG-coA Reductase Inhibitor on Rheumatoid Arthritis
The purpose of this study is: 1. To evaluate the prevalence of preclinical atherosclerosis in Chinese patients with RA compared to healthy controls. 2.
- Trial name
- NCT00555230
- Testing
- Rosuvastatin
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Chinese University of Hong Kong
Non-insulin-dependent Diabetes Mellitus
Rosiglitazone And Plaque Study for Type 2 Diabetes Mellitus
This is a phase IIIb, randomised, double blind, placebo controlled, study in patients with type 2 diabetes mellitus and coexisting vascular disease or hypertension. The total duration of the study will be approximately 60 weeks.
- Trial name
- NCT00231387
- Testing
- rosiglitazone
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- GlaxoSmithKline
Carotid Artery Diseases, Carotid Atherosclerosis
Prediction of Cerebral Hyperperfusion Syndrome After Carotid Revascularization Using Deep Learning
Cerebral hyperperfusion syndrome (CHS) was initially described as a clinical complication following carotid endarterectomy (CEA), but it may occur after both CEA and carotid artery stenting.
- Conditions
- Carotid Artery Diseases, Carotid Atherosclerosis, Carotid Artery Stenosis, Cerebral Hyperperfusion Syndrome
- Trial name
- NCT05800821
- Testing
- Carotid revascularization
- Where
- Belarus
- Volunteers
- 500 people
- Sponsor
- State Institution "Republican Scientific and Practical Center" Cardiology, Belarus
SLE, Atherosclerosis
Premature Atherosclerosis in Systemic Lupus Erythematosus
Patients with SLE have increased rates of atherosclerosis, while the risk factors for atherosclerosis in those patients were not fully revealed.
- Trial name
- PASLE (NCT04037293)
- Testing
- CIMT and baPWV measurement
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Peking Union Medical College Hospital
Carotid Stenoses
Stroke and Panorama - Analyzing Carotid Endocalcifications (SPACE)
The odontological radiology method Panorama is known to be able to spot calcifications in the area of the carotid arteries. The calcifications could be carotid stenoses which is affiliated with an increased risk of stroke.
- Trial name
- SPACE (NCT00514644)
- Testing
- Carotid ultrasound examination, Panorama examination
- Where
- Sweden
- Volunteers
- 266 people
- Sponsor
- Umeå University
Cardiovascular Diseases, Heart Diseases
Strong Heart Study
To determine morbidity and mortality from cardiovascular disease among American Indians and to compare cardiovascular disease risk factor levels among Indian groups living in different geographic areas.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Atherosclerosis, Asthma
- Trial name
- NCT00005134
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Atherosclerosis
Efficacy and Safety of Simvastatin-ezetimibe Combination Therapy Among Patients With SLE
This is a randomized single-blind trial. This study aimed to determine if intensive lipid-lowering therapy (simvastatin-ezetimibe combination therapy) could reduce the progression of atherosclerosis effectively and safely among…
- Trial name
- NCT02548936
- Testing
- Ezetimibe+Simvastatin Drug Combination
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking Union Medical College Hospital
Cardiac Arrest (CA), Return of Spontaneous Circulation
Pulse Detection in Cardiac Arrest Patients Using a Doppler Ultrasound Patch on the Carotid Artery
The purpose of this study is to find out if a Doppler ultrasound patch placed on the neck can accurately and quickly detect when a cardiac arrest patient's heart starts beating again (return of spontaneous circulation, or ROSC)…
- Conditions
- Cardiac Arrest (CA), Return of Spontaneous Circulation, CPR Quality Assessment
- Trial name
- NCT07729228
- Testing
- Ultrasound doppler perfusion monitoring
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Heartstream US LLC
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.