Clinical trials: Carotid Intima-media Thickness
Cardiovascular Diseases, Testicular Neoplasms
High-Intensity Aerobic Interval Training in Testicular Cancer Survivors
This study evaluates the impact of a supervised 12-week high-intensity aerobic interval exercise program (versus a self-directed exercise usual care group) on traditional and novel cardiovascular disease risk factors and…
- Trial name
- HIITTS (NCT02459132)
- Testing
- High-intensity aerobic interval exercise
- Volunteers
- 63 people
- Sponsor
- University of Alberta
Nasopharyngeal Carcinoma, Carotid Artery Diseases
Radiation-associated Carotid Artery Disease in Patients With Nasopharyngeal Carcinoma
Radiation-associated carotid vasculopathy is a common late sequelae in patients with head and neck cancer, which correlates with the incidence of stroke.
- Trial name
- NCT03568032
- Testing
- Measurement of intima media thickness of carotid artery, Detection and measurement of carotid plaques, Carotid Color Flow Duplex Testing
- Where
- China
- Volunteers
- 248 people
- Sponsor
- Fudan University
Cardiovascular Disease
Polypill Effects on Sub Clinical Atherosclerosis (PESCA) Trial
Medications that lower blood pressure and cholesterol are known to improve the shape and function of our blood vessels. These improvements include a reduction in the thickness of the wall of the carotid artery (the main artery…
- Trial name
- PESCA (NCT01326676)
- Testing
- Polypill: Red Heart Pill, Usual medication
- Where
- 3 sites in Ireland, Netherlands and 1 more
- Sponsor
- Imperial College London
Takayasu's Arteritis, Giant Cell Arteritis
Carotid Artery Neovascularization in Takayasu's and Giant Cell Arteritis
The purpose of this study is to evaluate the ability of contrast enhanced carotid ultrasound to serve as an indicator of disease activity in patients with Takayasu's arteritis or Giant Cell arteritis and to determine if patients…
- Conditions
- Takayasu's Arteritis, Giant Cell Arteritis, Arteritis, Vasculitis
- Trial name
- NCT01795456
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Sedentary Time, Cognitive Function
Standing Desk Converter & Habitual Posture
This project will determine the short-term impact of a standing desk converter on: 1) objectively measured physical activity and posture levels, and 2) brain (cognition) and heart (blood pressure regulation) function.
- Conditions
- Sedentary Time, Cognitive Function, Blood Pressure Regulation
- Trial name
- NCT05970588
- Testing
- Standing Promotion Intervention
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Olga Theou
Cardiovascular Diseases
Efficacy Study of Pioglitazone and Atorvastatin Combination Therapy in Treating Subjects With Elevated Risk for Cardiovascular Disease
The purpose of this study is to determine the effect of pioglitazone, once daily (QD), and atorvastatin combination therapy compared to atorvastatin monotherapy in patients at risk for cardiovascular disease.
- Trial name
- NCT00770575
- Testing
- Pioglitazone and atorvastatin, Atorvastatin
- Volunteers
- 148 people
- Sponsor
- Takeda
Prader-Willi Syndrome, Obesity
Plasma Adiponectin Level and Vascular Endothelial and Smooth Muscle Cell Function in Children With Prader-Willi Syndrome
Context: Prader-Willi syndrome (PWS) is a genetic disorder characterized by childhood-onset obesity and endocrine dysfunction that leads to cardiovascular disability and early death within the first 3 decades of life.
- Trial name
- NCT01479322
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Dialysis Patients, Hypertension
Carotid Intima-media Thickness in Dialysis Patients and Traditional Risk Factors
Cardiovascular disease (CVD) is the leading cause of mortality in hemodialysis (HD) patients. Carotid intima-media thickness (CIMT) is a validated surrogate marker for atherosclerosis.
- Conditions
- Dialysis Patients, Hypertension, Atherosclerosis
- Trial name
- NCT07558239
- Testing
- Ultrasound measurements of carotid intima- media thickness
- Volunteers
- 100 people
- Sponsor
- Minia University
Covid19, SARS-CoV Infection
Prognostic Value of Flow-mediated Dilation in Hospitalized COVID-19 Patients
This study will evaluate the associations between vascular parameters and clinical outcomes in patients hospitalized with COVID-19.
- Trial name
- NCT04714125
- Where
- Brazil
- Volunteers
- 250 people
- Sponsor
- University of Sao Paulo General Hospital
Hypertension, Target Organ Damage
GlycOxiTOD: Multimodal Vascular and Target-Organ Damage Registry
The goal of the GlycOxiTOD observational registry is to improve the early detection and characterization of vascular and other target-organ damage in adults at increased cardiovascular risk.
- Conditions
- Hypertension, Target Organ Damage, Heart Disease Risk Factors, Vascular Stiffness
- Trial name
- GlycOxiTOD (NCT06325800)
- Testing
- Multimodal Cardiovascular Phenotyping
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Complejo Hospitalario Universitario de Santiago
Obesity
Longitudinal Assessment of Cardiovascular and Metabolic Parameters in Obese and Lean Children
The investigators hypothesize that cardiovascular and metabolic alterations due to obesity already manifest at childhood age. To identify these alterations and risk factors, the investigators have established a cohort of 177…
- Trial name
- NCT01605123
- Where
- 2 sites in Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Atherosclerosis
A phase3 Study Measuring the Effect of Rosuvastatin 20 mg on Carotid Intima-Media Thickness in Chinese Subjects With Subclinical Atherosclerosis
The purpose of this study is to evaluate the effects of of rosuvastatin 20 mg compared to placebo for treating Chinese patients with subclinical atherosclerosis.
- Trial name
- NCT02546323
- Testing
- Rosuvastatin
- Where
- 24 sites in China
- Volunteers
- 543 people
- Sponsor
- AstraZeneca
Obese Adolescents
Associations Between Physical Activity and Sedentary Behavior Profiles and Carotid Intima-media Thickness in Adolescents With Obesity
Physical activity behaviors are key and modifiable factors of cardiovascular health from childhood. They encompass both physical activity, defined as any bodily movement produced by skeletal muscles that results in energy…
- Trial name
- CARADO (NCT07811115)
- Where
- France
- Volunteers
- 108 people
- Sponsor
- University of Avignon
Erectile Dysfunction, Arterial Hypertension
Correlation Study of Vascular Parameters in Hypertensive Men With Erectile Dysfunction
The purpose of the study is to assess the correlation of FMD of brachial artery and carotid intima media thickness with ED severity and clinical response to vardenafil in hypertensive men.
- Conditions
- Erectile Dysfunction, Arterial Hypertension, Endothelial Dysfunction
- Trial name
- NCT01084187
- Testing
- Vardenafil
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Hospital Universitario Pedro Ernesto
Type 1 Diabetes Mellitus, Coronary Artery Disease
Vascular Inflammation in Adolescents With Type 1 Diabetes
The purpose of this study is to find out if diabetes damages the blood vessels of adolescents with good diabetes control compared to adolescents with less optimal control.
- Trial name
- NCT00933101
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Children's Mercy Hospital Kansas City
Renal Insufficiency, Chronic
Omega 3 Fatty Acids in Patients With Chronic Renal Disease
To study the tolerance and efficacy of an omega 3 fatty acids supplement on renal and vascular function and inflammatory parameters in patients with chronic renal disease
- Trial name
- NCT03280615
- Testing
- Omega 3 fatty acids, Corn oil
- Where
- Chile
- Volunteers
- 100 people
- Sponsor
- University of Chile
Erectile Dysfunction Due to Arterial Disease
Carotid Artery Intima Media Thickness Can Predict the Response to Phosphodiesterase 5 Inhibitors in the Patients With Moderate Erectile Dysfunction
The aim of the present study was to examine the relationship between degrees of erectile dysfunction and carotid artery intima media thickness (CIMT) and its effect on the medical treatment of this disease.
- Trial name
- NCT05679999
- Testing
- CIMT (Carotid artery intima media thickness measurement)
- Where
- Turkey (Türkiye)
- Volunteers
- 181 people
- Sponsor
- Bursa City Hospital
Diabetes Mellitus
Efficacy Study of Pioglitazone and Glimepiride on the Rate of Progression of Atherosclerotic Disease.
The primary purpose of this study is to compare the effects of pioglitazone, once daily (QD), versus glimepiride on the amount of thickening of the carotid artery.
- Trial name
- CHICAGO (NCT00225264)
- Testing
- Pioglitazone, Glimepiride
- Where
- United States
- Volunteers
- 458 people
- Sponsor
- Takeda
Thalassemia
Adiponectin, IL-6 and hsC-RP in Relation to Carotid Intima-media Thickness in B-thalassemia Patients
Every year, 100,000 neonates are born with hemoglobinopathies around the world. Thalassemia is the most common heterogeneous disease of the human being .
- Trial name
- NCT03170245
- Testing
- Interleukin-6, HsC-RP, Adiponectin level
- Where
- Egypt
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Assiut University
Atherosclerosis, Cardiovascular Diseases
Investigating the Lowest Threshold of Vascular Benefits From LDL Cholesterol Lowering in Patients With Stable CV Disease
The INTENSITY-HIGH study aims to answer if there are any limits to LDL reduction in relation to benefiting vascular health, exploring the mechanisms by which secondary prevention in patients with established heart disease may…
- Trial name
- INTENSITY-HIGH (NCT03355027)
- Testing
- Alirocumab 150 MG/ML, Ezetimibe 10Mg Tablet, Atorvastatin 40Mg Tablet
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust