Clinical trials: Carotid Stenosis
Carotid Artery Stenosis, Carotid Artery Diseases
Study on the Trans-Carotid Artery Occlusion Shunt System Combined With Introducer Sets
The objective of the study is to evaluate the Safety and Efficacy of the Trans-Carotid Artery Occlusion Shunt System Combined with Introducer Sets for Cerebral Protection During Carotid Angioplasty
- Trial name
- NCT06959628
- Testing
- Trans-Carotid Artery Occlusion Shunt System Combined with Introducer Sets
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Shenzhen Wecan Medical Technology Co.,Ltd
Carotid Artery Stenosis, Carotid Artery Diseases
Protection Against Emboli During Carotid Artery Stenting Using the Neuroguard IEP System
A prospective, multicenter single-arm, open label study to evaluate the safety and effectiveness of the Neuroguard IEP System for the treatment of carotid artery stenosis in subjects at elevated risk for adverse events following…
- Conditions
- Carotid Artery Stenosis, Carotid Artery Diseases, Carotid Stenosis
- Trial name
- PERFORMANCE II (NCT04201132)
- Testing
- Carotid artery stenting with Neuroguard IEP System
- Where
- 38 sites in United States, Bulgaria and 4 more
- Volunteers
- 305 people
- Sponsor
- Contego Medical, Inc.
Cognitive Function in Carotid Stenting
Assessment of Cognitive Function in Patients Undergoing Carotid Artery Stent Placement
To determine the effect of carotid artery stenting, on cognitive function, in patients with high grade carotid artery stenosis
- Trial name
- NCT00919165
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Corewell Health West
Internal Carotid Artery Stenosis
EEG, Cerebral Oximetry, and Arterial to Jugular Venous Lactate to Assess Cerebral Ischemia During Carotid Endarterectomy
A highly desired result during carotid endarterectomy (CEA) is the ability to predict and warn the surgeon if the brain is at risk of damage during the period of time that the carotid artery is cross-clamped for surgical repair…
- Trial name
- NCT00737334
- Testing
- EEGo, BIS, FORE-SIGHT cerebral oximeter
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Carotid Artery Stenosis
Enterprise Stent Implantation in the Treatment of Carotid Artery Stenosis With Ischemic Stroke
To investigate the long-term effects of intracranial implantation of Enterprise stent system versus antiplatelet medication on neurologic deficits, daily living abilities, and carotid artery stenosis in patients with…
- Trial name
- NCT02802072
- Testing
- Enterprise stent implantation, Only aspirin medication
- Volunteers
- 100 people
- Sponsor
- Beijing Chao Yang Hospital
Carotid Stenosis, Coronary Artery Disease
Selective Coronary Revascularization in Carotid Artery Disease Patients After Carotid Revascularization (SCORECAD Trial)
The primary objective of this study is to determine whether among symptomatic and asymptomatic carotid artery stenosis (CAS) patients with no known coronary artery disease (CAD) who had undergone carotid artery revascularization…
- Trial name
- NCT06546761
- Testing
- Coronary CT angiography and FFRct analysis
- Where
- Latvia
- Volunteers
- 300 people
- Sponsor
- Pauls Stradins Clinical University Hospital
Carotid Stenosis
The Use of Anti-CD4 mAb-Fragment for Imaging of Local Inflammation in Patients With Carotid Artery Stenosis
The primary objective of this study is to proof the concept of EP 1645 as a diagnostic tool for carotid artery atherosclerosis and plaque instability and to assess the safety and tolerability of this diagnostic agent, a…
- Trial name
- NCT00904254
- Testing
- EP 1645/Solution For Injection, 99mTC
- Volunteers
- 21 people
- Sponsor
- Technische Universität Dresden
Cardiovascular Diseases, Carotid Stenosis
Recurrent Carotid Stenosis
To determine whether recurrent stenosis following carotid endarterectomy could be reduced by pre- and post-operative oral administration of platelet-inhibiting drugs.
- Conditions
- Cardiovascular Diseases, Carotid Stenosis, Cerebrovascular Disorders, Heart Diseases
- Trial name
- NCT00000527
- Testing
- aspirin, dipyridamole
- Sponsor
- Emory University
Patients With Aterosclerotic Carotid Stenosis, Symptomatic Patients (Stenosis > 50%)
The SIBERIA Trial (Acculink™ Versus CGuard™)
That the study will be carried out as it has the protocol instructions, respecting the applicable regulations for clinical investigations with medical devices and following the internationally accepted ethical standards
- Conditions
- Patients With Aterosclerotic Carotid Stenosis, Symptomatic Patients (Stenosis > 50%), Asymptomatic Patients (Stenosis ≥80%)
- Trial name
- CAS (NCT03488199)
- Testing
- Stent Acculink ™, CGuardTM™
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Carotid Artery Stenting, Carotid Endarterectomy
Carotid Revascularization Versus Best Medical Treatment for Asymptomatic Carotid Stenosis
This is a multicenter, open, randomized controlled trial to evaluate the efficacy and safety of carotid artery stenting/carotid endarterectomy versus best medical treatment for asymptomatic carotid artery stenosis in Chinese…
- Conditions
- Carotid Artery Stenting, Carotid Endarterectomy, Best Medical Treatment, Carotid Artery Stenosis Asymptomatic
- Trial name
- NCT05623904
- Testing
- Carotid Revascularization, Medical Treatment
- Where
- 11 sites in China
- Volunteers
- 1,056 people
- Sponsor
- Xuanwu Hospital, Beijing
Internal Carotid Artery Stenosis
Ultrasound-guided Intermediate Cervical Plexus Block
The investigators test with the present study design, whether an ultrasound-guided blockade of the cervical plexus in combination with an additional application of local anesthetic to the superficial cervical ansa (facial nerve…
- Trial name
- NCT02794974
- Testing
- cervical plexus block, facial nerve block, perivascular block
- Where
- Germany
- Volunteers
- 29 people
- Sponsor
- Helios Research Center
Carotid Artery Plaque
Study on Vulnerable Plaque of Carotid Artery With Chinese Herbal and Insects Medicine
The investigators want treat Vulnerable plaque of carotid artery with a herbal and insects Chinese medicine. Designing a RCT trial to prove the effect and safety.
- Trial name
- Spchim (NCT03072225)
- Testing
- Herbal Medicine C-117
- Volunteers
- 120 people
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Cystic Fibrosis, Endothelial Dysfunction
Vascular Health and Function in Cystic Fibrosis
The goal of this observational study is to learn whether blood vessel health and function differ between adults aged 40 years or older with cystic fibrosis (CF) who are taking CFTR modulator therapy and healthy adults of the same…
- Conditions
- Cystic Fibrosis, Endothelial Dysfunction, Cardiovascular Risk Factor
- Trial name
- CF-VHF (NCT07904325)
- Testing
- Non-invasive vascular, cerebrovascular and autonomic assessment
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Carotid Artery Stenosis Symptomatic, Carotid Endarterectomy (CEA) Surgical Patients
Correlation Between Carotid Stump Pressure and Interhemispheric rSO₂ Asymmetry During Awake Carotid Endarterectomy
This study aims to better understand how well the brain is perfused (supplied with blood and oxygen) during a specific type of surgery called carotid endarterectomy (CEA), which is performed to prevent strokes in people with…
- Conditions
- Carotid Artery Stenosis Symptomatic, Carotid Endarterectomy (CEA) Surgical Patients, Cerebral Hypoperfusion
- Trial name
- NCT07150260
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Izmir Katip Celebi University
Carotid Artery Disease, Symptomatic Carotid Artery Stenosis
High Coverage CARotid Stenting vs. Medical Management Alone to Prevent EmboliSm From symptomaTic Non-stenotic cARotid Disease (SyNC)
Goal is to analyse the clinical safety and efficacy of the CARESTO® heal Stent within standard clinical routine for the treatment of patients with symptomatic non-stenotic carotid disease (SyNC) and with high-risk plaque features…
- Conditions
- Carotid Artery Disease, Symptomatic Carotid Artery Stenosis, Carotid Artery Stenting, Carotid Plaque Imaging
- Trial name
- CARESTAR (NCT07166731)
- Where
- Germany
- Volunteers
- 536 people
- Sponsor
- Acandis GmbH
Carotid Stenosis
Noninvasive Evaluation for Carotid Artery Stenosis: The Carotid Stenotic Scan
The purpose of this study is to determine the accuracy of a new non-invasive device, the Carotid Stenotic Scan (CSS), to check for stenosis of the internal carotid artery (ICA) as compared to a carotid duplex ultrasound study.
- Trial name
- CSS (NCT04057183)
- Testing
- Carotid Stenotic Scan
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Phillip J Bendick
Carotid Artery Diseases, Hypothermia
Body Cooling During Carotid Endarterectomy: No-profit, Open, Mono-centric, Feasibility Study
Aim of the study is to determine whether endovascular systemic cooling to a target temperature of 34-35°C initiated before, and maintained during Carotid EndoArterectomy (CEA), is feasible and safe
- Conditions
- Carotid Artery Diseases, Hypothermia, Stroke, Carotid Artery Plaque
- Trial name
- NCT02629653
- Testing
- endovascular cooling (Zoll system)
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- S. Andrea Hospital
Carotid Artery Diseases, Carotid Artery Stenosis
A Lithium-Based Medication to Improve Neurological Outcomes After Surgical Carotid Reconstruction
There are 10.3 million cases of stroke registered in the world every year; 63% of them lead to death. According to World Health Organization, stroke is one of the most important risk factors of death and early disability.
- Trial name
- NCT05126238
- Testing
- Lithium Carbonate
- Where
- Russia
- Volunteers
- 107 people
- Sponsor
- Negovsky Reanimatology Research Institute
Carotid Stenosis, Caloric Restriction
Short-Term Endogenous Hydrogen Sulfide Upregulation
This research study will compare the impact of dietary restriction pre-operatively before carotid endarterectomy compared to the standard nutrition that a patient typically eats.
- Trial name
- NCT03303534
- Testing
- ScandiShake
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Brigham and Women's Hospital
Carotid Artery Stenosis
Impact of Aspiration Thrombectomy During Carotid Stenting
The purpose of this study is to determine whether aspiration thrombectomy following carotid stent deployment will reduce the number of procedure related signals as identified by diffusion weighted MRI of the brain.
- Trial name
- NCT01550835
- Testing
- Emboshield NAV6® embolic protection system (Abbott Vascular, Santa Clara, CA)
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Fogarty Clinical Research Inc.