Clinical trials: Carotid Surgery
Moyamoya Disease, Ischemic Cerebral Infarction
NBP in Patients With Moyamoya Disease of High Risk for Ischemic Cerebrovascular Events
An extracranial-to-intracranial (EC-IC) revascularization is the most widely used treatment to improve cerebral perfusion in patients with moyamoya disease (MMD), and it has been shown to reduce the risk of subsequent stroke and…
- Conditions
- Moyamoya Disease, Ischemic Cerebral Infarction, Ischemic Stroke, Ischemic Cerebrovascular Accident
- Trial name
- NICE-MMD (NCT04205578)
- Testing
- dl-3-n-butylphthalide (NBP), Normal Saline 0.9% Infusion Solution
- Where
- 2 sites in China
- Volunteers
- 450 people
- Sponsor
- yuanli Zhao
Carotid Artery Occlusion
Effectiveness of Surgical and Diagnostic Methods in Cerebral Vascular Occlusive Disease
This study attempts to improve surgical treatment outcomes among people with chronic carotid artery occlusive disease by conducting a comprehensive review of neuroradiological, clinical, and cognitive data.
- Trial name
- NCT07396025
- Testing
- Revascularization/Conservative management
- Where
- Kazakhstan
- Volunteers
- 60 people
- Sponsor
- National Centre for Neurosurgery, Republic of Kazakhstan
Cervical Plexus Block Comparison
Medial Cervical Block for Carotid Endarterectomy Comparison With Standard Method
The purpose of the study is to compare efficacy, complications and safety of the standard method of Combined (superficial and deep) cervical plexus block (SDCPB) with Ultrasound guided Medial Cervical plexus block technique…
- Trial name
- NCT01608126
- Testing
- cervical block
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Daniel Nalos MD
Carotid Stenosis, Surgery
Revascularization of Extracranial Carotid Artery Stenosis
Investigate the current situation of carotid stenosis therapy in China. Establish the data bank of carotid stenosis revascularization (CAS and CEA) in China ,in order to get best quality control of the therapy, as well as confirm…
- Conditions
- Carotid Stenosis, Surgery, Stroke
- Trial name
- RECAS (NCT01994187)
- Testing
- Carotid endarterectomy, carotid angioplasty
- Where
- China
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Carotid Endarterectomy, Coronary Artery Bypass Grafting
Multidisciplinary CAE and CABG Surgery to Optimize the Management of High-risk Patients During the Perioperative Period
This project uses concurrent CEA+CABG combined surgery on high-risk patients with severe carotid artery stenosis and severe coronary artery stenosis.
- Trial name
- NCT04960488
- Testing
- carotid endarterectomy and coronary artery bypass grafting
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University Third Hospital
Coronary Artery Disease, Arteriosclerosis
Associations Between Diabetes, Arterial Stiffness and Fibulin-1 in Patients Undergoing Heart- and Vascular Surgery?
Diabetes Mellitus (DM) is frequently appearing in patients with cardiovascular disease and these patients, as a consequence herby, has a lesser prognosis. DM is often related to increased arterial stiffness and hypertension.
- Conditions
- Coronary Artery Disease, Arteriosclerosis, Carotid Stenosis, Thrombosis
- Trial name
- NCT01106573
- Where
- Denmark
- Volunteers
- 1,400 people
- Sponsor
- Odense University Hospital
General Anesthesia Induction for Elective Surgery
Carotid Artery Corrected Flow Time as a Predictor of Hypotension After Induction of General Anesthesia in Elderly Patients
The number of elderly patients undergoing elective surgery has been growing in recent years. Elderly patients often have a variety of underlying diseases, including hypertension, coronary heart disease, diabetes…
- Trial name
- NCT05628051
- Testing
- ultrasonographic measurement of carotid artery corrected flow time (FTc)
- Where
- China
- Volunteers
- 177 people
- Sponsor
- Fujian Medical University Union Hospital
Abdominal Aortic Aneurysm, Carotid Atherosclerosis
Preconditioning Shields Against Vascular Events in Surgery
Major vascular surgery involves operations to repair swollen blood vessels, clear debris from blocked arteries or bypass blocked blood vessels.
- Conditions
- Abdominal Aortic Aneurysm, Carotid Atherosclerosis, Critical Lower Limb Ischaemia
- Trial name
- SAVES-F (NCT02097186)
- Testing
- Remote ischaemic preconditioning
- Where
- 6 sites in Ireland
- Volunteers
- 400 people
- Sponsor
- Mid Western Regional Hospital, Ireland
Endarterectomy, Carotid
Effects of Dexmedetomidine on the Intraoperative Electroencephalogram During Endarterectomy Surgery
During elective carotid endarterectomy surgery, dexmedetomidine, an FDA approved medication, is now given as part of our standard anesthetic regimen based upon its reported ability to decrease anesthetic requirements and improve…
- Trial name
- NCT00710437
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, Davis
a Myocardial Infarction, Coronary Artery Bypass Graft Surgery Percutaneous Transluminal Coronary Angioplasty Stent Placement
The Effects of an Intensive Lifestyle Modification Program on Carotid Artery Intima-Media Thickness
The objective of this study is to evaluate the effect of the Ornish Program on cardiovascular disease as measured by the IMT of the common carotid artery, and to compare this effect to outcomes from patients participating in…
- Trial name
- NCT00243581
- Testing
- Dean Ornish Heart Disease Reversing Program
- Sponsor
- SwedishAmerican Health System
Moyamoya Disease
Prognostic Prediction Model in Patients With Moyamoya Disease Undergoing Revascularization Surgery
Moyamoya Disease (MMD) is a rare chronic cerebrovascular disease characterized by progressive occlusion of the internal carotid artery or its major branches, with blood flow compensated by the formation of an abnormal vascular…
- Trial name
- NCT06051552
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Beijing Tiantan Hospital
Ischemic Stroke
Decoding Risks and Rewards in Ischemic Stroke Surgery
In the high-stakes battle against ischemic cerebrovascular disease, where every second counts and the margin for error is slim, how do the investigators tip the scales in favor of patient survival and improved outcomes? This…
- Trial name
- NCT06098066
- Where
- Taiwan
- Volunteers
- 204,411 people
- Sponsor
- China Medical University Hospital
Carotid Stenosis
Differences of the Postoperative Outcome for Carotid Surgery Patients Treated by Either Male or Female Surgeons
This research will focus on the differences of the postoperative outcome for carotid surgery patients treated by either male or female surgeons.
- Trial name
- NCT06485102
- Testing
- Carotid Surgery in patients with symptomatic or asymptomatic stenosis
- Where
- Germany
- Volunteers
- 800 people
- Sponsor
- University Hospital Augsburg
Aneurysm, Dissection
PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches
The purpose of this registry is to collect safety and performance data on all commercially available Terumo Aortic knitted and woven grafts, and cardiovascular patches in standard clinical practice.
- Conditions
- Aneurysm, Dissection, Aortic Root Aneurysm, Aortic Root Dissection
- Trial name
- PANTHER (NCT04545502)
- Testing
- Gelsoft Plus Vascular Graft, Vascular Bypass Graft, Cardiovascular Patch
- Where
- 30 sites in United States, Belgium and 4 more
- Volunteers
- 2,000 people
- Sponsor
- Vascutek Ltd.
Carotid Artery Diseases, Peripheral Artery Disease
Assessment of Carotid Artery Stenosis and Lower Limb Peripheral Ischemia Prior to CABG
From our experience among Egyptian population in our institution, there is an increased prevalence of hidden subclinical peripheral artery disease along with carotid artery affection.
- Trial name
- NCT03516929
- Testing
- carotid duplex, both LL arterial duplex
- Where
- Egypt
- Volunteers
- 360 people
- Sponsor
- Mr Ihab Ali
Vascular Diseases, Carotid Artery Diseases
Frailty in Vascular Patients Undergoing Surgery
An observational cohort study of the frailty of vascular surgery patients undergoing intervention and their outcomes.
- Conditions
- Vascular Diseases, Carotid Artery Diseases, Aneurysmal Disease, Peripheral Artery Disease
- Trial name
- NCT03668821
- Testing
- Questionnaire
- Where
- 2 sites in United Kingdom
- Volunteers
- 300 people
- Sponsor
- Imperial College London
Carotid Artery Diseases, Carotid Artery Stenosis
A Lithium-Based Medication to Improve Neurological Outcomes After Surgical Carotid Reconstruction
There are 10.3 million cases of stroke registered in the world every year; 63% of them lead to death. According to World Health Organization, stroke is one of the most important risk factors of death and early disability.
- Trial name
- NCT05126238
- Testing
- Lithium Carbonate
- Where
- Russia
- Volunteers
- 107 people
- Sponsor
- Negovsky Reanimatology Research Institute
Carotid Artery Stenosis, Image
Evaluation of Brain Health and Surgical Efficacy in Patients With Carotid Artery Stenosis
The purpose of this study is to explore the relationship between the recovery of cerebrovascular morphology and cognitive function before and after surgical treatment in patients with carotid artery stenosis and their…
- Trial name
- NCT05848921
- Testing
- magnetic resonance image, Neuropsychological scale
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nanjing University of Traditional Chinese Medicine
Ischemic Postconditioning, Carotid Surgery
Ischemic Postconditioning in Carotid Surgery
Analyzing changes in cerebral oximetry, transcranial Doppler and biomarkers of neuronal ischemic injury and blood-brain barrier integrity assessing the safety and efficacy of ischemic postconditioning in carotid surgery (IPCT).
- Conditions
- Ischemic Postconditioning, Carotid Surgery, Stroke, Carotid Artery Diseases
- Trial name
- BRAIN-SAVE (NCT06359756)
- Testing
- Ischemic postconditioning in carotid surgery, Eversion Carotid Endarterectomy
- Where
- Serbia
- Volunteers
- 40 people
- Sponsor
- Institute for Cardiovascular Diseases Dedinje
Systolic Heart Failure, Peripheral Chemoreceptor Hypersensitivity
Bilateral Surgical Resection of Carotid Bodies in Patients With Systolic Heart Failure
The primary aim of the study is to determine safety, tolerability and feasibility of bilateral carotid body resection in patients with systolic heart failure and peripheral chemoreceptor hypersensitivity.
- Trial name
- NCT01782677
- Testing
- Bilateral Surgical Resection of Carotid Bodies
- Where
- Poland
- Volunteers
- 5 people
- Sponsor
- Noblewell