Clinical trials: Case Management
Keratoconus
Evaluation of Safety and Efficacy of a Bioengineered Corneal Implant for Treatment of Keratoconus
This is a prospective, Phase I open-label safety study to evaluate the safety, feasibility and initial efficacy of a bioengineered corneal stromal substitute after implantation into the stroma of adults with advanced keratoconus.
- Trial name
- LinkCor (NCT04653922)
- Testing
- LinkCor Bioengineered Corneal Implant
- Where
- 2 sites in India, Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- LinkoCare Life Sciences AB
Slipped Capital Femoral Epiphysis
Management of Slipped Capital Femoral Epiphysis (SCFE) on Top of Fixed Fracture Neck of Femur Case Report.
Slipped Capital Femoral Epiphysis (SCFE) on Top of Fixed Fracture Neck of Femur managed by subtrochanteric valgus osteotomy
- Trial name
- SCFE (NCT05758051)
- Testing
- subtrochanteric valgus osteotomy
- Where
- Egypt
- Volunteers
- 1 people
- Sponsor
- Assiut University
Aortic Valve Disease
Aortic Root Enlargement Versus Aortic Root Replacement in the Management of Cases With Small Aortic Root
Each type of Aortic valve surgery has its advantages and disadvantages; we aim to differentiate between two types of aortic valve surgery: aortic root replacement (using either Ross procedure or stentless bioprosthesis procedure)…
- Trial name
- NCT05167539
- Testing
- Aortic valve surgery
- Volunteers
- 100 people
- Sponsor
- Assiut University
Clinical Decision-making
Physician Reasoning on Management Cases With Large Language Models
This study will evaluate the effect of providing access to GPT-4, a large language model, compared to traditional management decision support tools on performance on case-based management reasoning tasks.
- Trial name
- NCT06208423
- Testing
- GPT-4
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Stanford University
Malaria
Evaluation of Targeted Mass Drug Administration for Malaria in Ethiopia
Reactive and proactive case detection measures are widely implemented by national malaria elimination programs globally. Similarly, the Ethiopian Federal Ministry of Health decided to include reactive case detection (RCD) and…
- Trial name
- NCT04241705
- Testing
- Treatment of positive individuals per national treatment guidelines, Presumptive treatment with artemether-lumefantrine (AL) plus 14 days of primaquine (PQ), Optimized malaria control interventions
- Where
- 10 sites in Ethiopia
- Volunteers
- 48,960 people
- Sponsor
- Armauer Hansen Research Institute, Ethiopia
Depression and Burden in Caregivers
Health-eBrain Study
The purposes of this study are to (1) track dementia caregiver health indicators over 12 weeks, both with and without the Mindoula plus DANA intervention (case manager and mobile messaging and assessment applications) to…
- Trial name
- HeB (NCT02903862)
- Testing
- Mindoula, DANA
- Where
- United States
- Sponsor
- AnthroTronix, Inc.
Eating Disorders
Severe and Enduring Eating Disorder Patients at Stockholms Center for Eating Disorders in Sweden
Patients with severe and enduring eating disorders (SEED) are seriously ill and have a low quality of life. In 2014, a special unit based on case management (CM), for patients with SEED (the Eira unit) was started at Stockholm…
- Trial name
- SEED (NCT02897622)
- Testing
- Case management
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Giant Thoracic Herniation, Myelopathy
Management of Giant Thoracic Disc Hernias by Thoracoscopy: Experience of 52 Cases
Introduction: Giant thoracic disc herniation is a rare condition for which surgical treatment is indicated when there are signs of spinal cord injury.
- Trial name
- GHTT (NCT03295617)
- Testing
- Thoracoscopy
- Where
- France
- Volunteers
- 52 people
- Sponsor
- Hopital Foch
HIV Seronegativity, Linkage
Linkage of Transgender Individuals to PrEP
CCTG 602 is a multisite demonstration project to evaluate the effectiveness of facilitated linkage to PrEP using a community-based transgender PrEP outreach worker (T-POWr) versus standard of care (SOC).
- Trial name
- NCT03191474
- Testing
- T-POWr Intervention
- Where
- 2 sites in United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Urogenital Diseases, Nerve Block
Comparison of the Efficacy of Sacral Espb and Caudal Block for Pain Management After Urogenital Surgeries in Children
The aim of this study was to compare the efficacy of caudal block and sacral espb used as a postoperative analgesia method in urogenital pediatric surgery cases.
- Conditions
- Urogenital Diseases, Nerve Block, Pain, Postoperative
- Trial name
- SESPB (NCT06373185)
- Testing
- Ultrasound-guided sacral erector spinae plane block, Ultrasound-guided caudal block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Giresun University
Gastric GIST, Submucosal Tumor of Stomach
Laparoscopic Management of Gastrointestinal Stromal Tumor of Stomach
Gastric GISTs are rare neoplasms that require excision for cure. Although the feasibility of laparoscopic resection of gastric GIST less than 2cms has been established, the feasibility, safety and long-term efficacy of these…
- Trial name
- NCT03722056
- Testing
- Laparoscopic resection
- Volunteers
- 42 people
- Sponsor
- GEM Hospital & Research Center
Pneumonia
Community Case Management of Chest Indrawing Pneumonia
This one-arm safety intervention study is aimed at increasing access to treatment of pneumonia by training CHWs, locally referred to as Community Oriented Resource Persons (CORPs), to manage chest indrawing pneumonia using oral…
- Trial name
- NCT02878031
- Testing
- Oral amoxicillin for CI pneumonia
- Where
- Nigeria
- Volunteers
- 191 people
- Sponsor
- Malaria Consortium
Quality Improvement, Public Health
To a Sustainable Quality Policy
The investigators need stronger feedback loops and a quality monitoring and management system to improve the quality of care in sustainable way.
- Conditions
- Quality Improvement, Public Health, Management Systems
- Trial name
- NCT04200209
- Testing
- Implementation of a quality indicator feedback mechanism
- Where
- Belgium
- Volunteers
- 400 people
- Sponsor
- KU Leuven
Coronary Heart Disease, Multimorbidity
Randomized Control Trial to Evaluate Effectiveness of a Case Managment Program Regarding Psychosocial Well-being and Disease Symptoms Health for Patients With Multimorbid Coronary Heart Disease (CHD) Patients (KHK ProMA)
This randomized controlled trial (RCT) will examine a case management program for patients suffering from coronary heart disease with multimorbidity in Mannheim, Germany.
- Trial name
- KHK ProMA (NCT01725074)
- Testing
- Case Management "CM CHD", Social Interaction
- Where
- Germany
- Volunteers
- 320 people
- Sponsor
- Genossenschaft Gesundheitsprojekt Mannheim e.G
Psychotic Disorders
Critical Time Intervention in the Transition From Hospital to Community in People With Severe Mental Illness
This study will evaluate the effectiveness of a psychosocial treatment, Critical Time Intervention, in easing the transition from hospital to community in people with severe mental disorders.
- Trial name
- NCT00621465
- Testing
- Critical Time Intervention (CTI), Usual care
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- New York State Psychiatric Institute
Depression
An Integrated Model of Primary Care in Mental Health
Managed care systems rely on primary care providers as gatekeepers to make sensible decisions regarding the use of expensive health care resources.
- Trial name
- NCT00013260
- Testing
- Integrated model of primary care
- Where
- United States
- Volunteers
- 271 people
- Sponsor
- US Department of Veterans Affairs
Acute Stroke
Michigan Stroke Transitions Trial
The Michigan Stroke Transitions Trial (MISTT) is a patient-centered randomized control trial that aims to improve the experience of stroke patients after they return home.
- Trial name
- MISTT (NCT02653170)
- Testing
- SCM, SCM and VSSP
- Where
- 3 sites in United States
- Volunteers
- 320 people
- Sponsor
- Michigan State University
Mental Disorders
Improving Primary Care in Patients With Mental Disorders
This study will determine the effectiveness of medical case management in improving the medical care of people with mental disorders or substance abuse problems.
- Trial name
- NCT00183313
- Testing
- Nurse case management, Usual care
- Where
- 2 sites in United States
- Volunteers
- 407 people
- Sponsor
- Emory University
Tracheal Stenosis
Challenges and Management of Post-intubation Tracheal Stenosis
Management of a "difficult airway" remains one of the most relevant and challenging tasks for anesthesiologists and pulmonary physicians.
- Trial name
- NCT06061380
- Testing
- no intervation taken
- Where
- Ethiopia
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Wollo University
Open Wound
Prospective Case Series Evaluating the Efficacy and Safety of NeoThelium FT for Open Wounds
This is a prospective case series evaluating the efficacy and safety of NeoThelium FT Amnion Skin Graft in the Mangement of Open Wounds
- Trial name
- NCT07041177
- Testing
- NeoThelium FT
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- NuScience Medical Biologics, LLC