Clinical trials: Case-control Study
Periodontitis
Association of Herpesvirus and Periodontitis
A significant influence of the Herpes viruses family in the progression of periodontal disease has been suggested. The aim of this study was to investigate the potential association of four Herpes viruses (HSV-1, HSV-2, CMV and…
- Trial name
- HerPerio (NCT05631288)
- Testing
- Sampe collection
- Where
- Portugal
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Miguel de Araújo Nobre
Niemann-Pick Disease, Type C1
Study of Lithium Carbonate to Treat Niemann-Pick Type C1 Disease
This study is planned to study whether lithium carbonate has protective effect on the brain of Niemann-Pick disease type C1.
- Trial name
- NCT03201627
- Testing
- Lithium Carbonate
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Pelvic Girdle Pain
Biomechanical Effects of Wearing a Sacroiliac Belt in Women
Women with pelvic girdle pain PGP) often get relief from using a sacroiliac belt. The study will explore if there are differences and in the changes of lower body movement in stability with the belt on and with the belt off.
- Trial name
- NCT03334799
- Testing
- sacroiliac belt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Multi-drug Resistant Tuberculosis
Case Control Study of Vitamin D Status and Adult Multidrug-resistant Pulmonary Tuberculosis in Maharashtra, India
India has the highest incidence of and mortality from multi-drug resistant tuberculosis (MDR-TB) globally. Vitamin D status may be an important determinant of MDR-TB infection and treatment outcomes; however, observational…
- Trial name
- NCT04342598
- Testing
- Serum Vitamin D
- Where
- India
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Specific Learning Disorder, Gait
Single and Dual Task Gait Parameters in Children With Specific Learning Difficulties
Children with spesific learning disorders have differences in motor and cognitive abilities compared to normal developing children.
- Trial name
- NCT04783987
- Testing
- Walking asessments
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Afyonkarahisar Health Sciences University
Ovarian Cancer
Evaluation of Polygenic Risk Score for Epithelial OVarian cancEr Risk Prediction: the PROVE Study
The goal of this observational study is to evaluate whether polygenic risk score (PRS) assessment can help predict the onset of epithelial ovarian cancer in women aged over 18, comparing those with a histologically confirmed…
- Trial name
- PROVE (NCT06935344)
- Testing
- Polygenic Risk Score, Biopsy on normal contralateral ovary, Pharmacogenetic profiles
- Where
- Italy
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Metabolic Syndrome, Coronary Artery Disease
A Case Control Study of Resveratrol Effects in Coronary Artery Disease Patients With Metabolic Syndrome
The aim of this study is to explore the role of Canonical β-catenin/Wnt and forkhead box O (FOXO) pathways by means of investigating their target genes in coronary artery disease (CAD) pathogenesis and to examine the effects of…
- Trial name
- NCT02137421
- Testing
- Resveratrol (3, 4´, 5 trihydroxystilbene)
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Multivessel Coronary Artery Disease
The Catholic University BIMA Grafting Study
The present study hypothesizes that the systematic use of bilateral internal mammary artery (BIMA) grafting is feasible in the practice of a University Cardiac Surgery Institution for the treatment of multivessel coronary artery…
- Trial name
- CATHEXIS (NCT01593865)
- Testing
- BIMA Grafting, Left-only mammary artery grafting
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Catholic University, Italy
Gingival Phenotype
Comparison of Microneedling and CTG for Gingival Augmentation- A RCT
The presence study is toComparison of Microneedling with Subepithelial Connective Tissue Auto Graft for Gingival Augmentation- A Randomized Case Control Trial.
- Trial name
- NCT06060119
- Testing
- microneedling
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Myocarditis, Ventricular Arrhythmia
Image-Based Prediction of Ventricular Tachycardias in Post-Myocarditis Patients: an International Multicenter Case-control Study
Ventricular arrhythmias (VAs) are frequently associated with structural heart diseases (SHD) such as myocardial infarction, myocarditis, and non-ischemic cardiomyopathies.
- Trial name
- MYOCARDITIS-VT (NCT06730607)
- Where
- 3 sites in Italy, Spain
- Volunteers
- 150 people
- Sponsor
- Centro Medico Teknon
Phenylketonuria
SNAP: Study Nutrients in Adult PKU
Phenylketonuria (PKU) is a rare inherited metabolic disorder, where subjects are born with a genetic deficiency in the phenylalanine hydroxylase enzyme (PAH), which leaves them unable to convert Phenylalanine (Phe) into Tyrosine…
- Trial name
- SNAP (NCT03858101)
- Where
- 4 sites in Belgium, Denmark and 1 more
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Low Back Pain
Influence of Kinesiophobia on the Outcome of Chronic Low Back Pain Condition
Though large body of evidence reported association between pain and kinesiophobia, there are paucity of studies in associating kinesiophobia to muscle endurance and position sense in patients with Chronic lower back pain [CLBP].
- Trial name
- NCT05079893
- Testing
- Case control study
- Volunteers
- 600 people
- Sponsor
- Gulf Medical University
Neutrophil-mediated Inflammatory Dermatoses, Inflammatory Dermatoses
Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases
This study is to identify rare, disease-causing mutations of several rare neutrophil dermatoses. To identify associations between NMID and variants in the genome next generation sequencing, mainly whole exome sequencing, will be…
- Trial name
- NEUTROSKIN (NCT05732987)
- Testing
- Analysis of samples
- Where
- Switzerland
- Volunteers
- 3,370 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Peri-Implantitis, Sinusitis
"Association of Peri-implantitis and Maxillary Sinusitis: a Case-control Study".
Scientific evidence regarding the influence of peri-implantitis on Schneider's membrane thickening is scarce and limited. Similarly, to date, there is no literature documenting the resolution of implant-associated maxillary…
- Conditions
- Peri-Implantitis, Sinusitis, Sinusitis, Acute, Sinusitis, Chronic
- Trial name
- NCT05924711
- Testing
- Retrospective analysis of demographic and radiographic data previously obtained from the patient.
- Where
- 2 sites in Spain
- Volunteers
- 40 people
- Sponsor
- Universitat Internacional de Catalunya
Retinal Detachment Multiple Breaks
Redetachment Under Densiron for RD Multiple Breaks
Densiron is used as a tamponading agent for inferior retinal detachment with inferior retinal breaks However, data about the use of Densiron -68 for RRD with multiple retinal breaks; especially if involving both superior and…
- Trial name
- Densiron (NCT05716971)
- Testing
- Densiron-68 (heavy silicone oil) tamponade for retinal detachment
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Dar El Oyoun Hospital
Cancer
The Vallania Study: A Case Control Study for the Development of Multiomics Blood Tests for Cancer Screening
This protocol is a case-control, multicenter, diagnostic study to collect blood samples to support the development of blood-based screening tests for multiple cancers.
- Trial name
- NCT05254834
- Testing
- Freenome Test
- Where
- 68 sites in United States
- Volunteers
- 7,435 people, healthy volunteers welcome
- Sponsor
- Freenome Holdings Inc.
Kawasaki Disease
Etiology Study of Kawasaki Disease
The purpose of this study is to investigate the infectious etiology of Kawasaki disease (KD); a prospective household and case control study for Kawasaki disease will be done.
- Trial name
- NCT00154596
- Where
- Taiwan
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Premature Ovarian Insufficiency
Evaluation on Biological Characteristics of Acupoints in Premature Ovarian Insufficiency
Acupuncture has been widely used in the treatment of Premature Ovarian Insufficiency(POI), but the selection of acupoints is indeterminate and lacks biological basis.In recent years,some studies suggested the "acupoint…
- Trial name
- NCT06145061
- Testing
- all patients and healthy people will receive at least 3 infrared thermal imaging examinations of acupoints and pain threshold examinations of acupoints.
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Xiaomei Shao
Vitamin D Deficiency, Periodontitis
25-Hydroxyvitamin D Levels in Patients With Periodontitis (Stage III)
Periodontitis; is an inflammatory disease of tissues characterized by bone destruction around the teeth. Vitamin D plays an important role in several inflammatory diseases by promoting the expression of inflammatory cytokines…
- Trial name
- NCT05343273
- Testing
- taking a blood sample
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Whooping Cough
Effectiveness of Maternal Immunization With Boostrix at Preventing Pertussis Among Infants <2 Months Old in the United States
The purpose of this study is to estimate the effectiveness of maternal immunization with Boostrix at preventing pertussis in infants in the United States.
- Trial name
- NCT03973905
- Testing
- Not applicable / dataset analysis
- Where
- Belgium
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.