Clinical trials: Case-control Study
Kidney Transplant
Effects of Personalized Physical Rehabilitation in Kidney Transplant Recipients
This randomized controlled trial (RCT) will examine the effect of a novel 12 month personalized exercise rehabilitation program compared to standard care following kidney transplantation.
- Trial name
- NCT02409901
- Testing
- Exercise Rehabilitation
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- University of Illinois Chicago
REM Sleep Behavior Disorder
Prodromal Markers in Recurrent Dream Enactment Behaviors Without REM Sleep Without Atonia
REM sleep behavior disorder is a novel and distinct parasomnia characterized by recurrent dream enactment behaviors (DEBs) and REM sleep without atonia (RSWA) during polysomnographic assessment, with a male predominance and…
- Trial name
- NCT05353881
- Testing
- No intervention
- Where
- Hong Kong
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Mild Cognitive Impairment
A Single-center, Self-controlled, Prospective Case Series Pilot Study to Assess the Effect of Lamivudine (3TC) on Neurocognitive Impairment Biomarkers and Type-I IFN (Interferon)-Stimulated Genes in the Plasma of Patients With Mild Cognitive Impairment (MCI)
To assess the ability of lamivudine to lower the levels of neurocognitive impairment biomarkers in the plasma of patients with MCI and positive AD biomarkers in a 24 weeks-treatment period.
- Trial name
- NCT06519357
- Testing
- Lamivudine 300 MG
- Where
- Spain
- Volunteers
- 23 people
- Sponsor
- Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
Mpox (Monkeypox)
Epidemiological and Clinical Characteristics of Mpox Outbreak in Equateur, the DR Congo (Part1)
The goal of this observational study is to characterize the clinical features of the 2024 mpox outbreak in Equateur Province of DRC and to identify associated risk factors.
- Trial name
- NCT07055867
- Where
- Democratic Republic of the Congo
- Volunteers
- 122 people
- Sponsor
- Osaka Metropolitan University
Papillary Thyroid Carcinoma, Thyroid Cancer
Cross-sectional Case and Control Study on Quality of Life, Appearance and Functions in PTC Via Different Surgical Approach
An observational cross-sectional case-control study on the postoperative quality of life (5 aspects, general quality of life, thyroid specific quality of life, scar appearance, voice and swallowing functions) of papillary thyroid…
- Trial name
- NCT05932121
- Testing
- Thyroid lobectomy via trans-axillary approach, Thyroid lobectomy via open approach
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking Union Medical College Hospital
Case-control Study
GENETIC SUSCEPTIBILITY FACTOR AS A PREDICTOR OF TYPE 2 DIABETES REMISSION AND WEIGHT LOSS AFTER BARIATRIC SURGERY
Obesity is directly related to an increased risk of diabetes mellitus, hypertension, dyslipidemia, cardiovascular disease, and overall mortality. Weight loss is effective in decreasing these risks and to reduce disease severity.
- Trial name
- OBEGEN (NCT02405949)
- Testing
- Genetic test
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Psoriasis, Nonalcoholic Fatty Liver Disease
A Case Control Study Evaluating the Prevalence of Non-Alcoholic Fatty Liver Disease Among Patients With Psoriasis
Main objectives 1. Establish the association of psoriasis and the presence of NAFLD in the patients with psoriasis attending dermatologic clinic center. Secondary objective 1.
- Trial name
- NCT00930384
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- George Washington University
Tuberculosis (TB)
Cardiometabolic Risk Factors Associated With Multidrug-Resistant Tuberculosis
Background: MDR-TB (Multidrug Resistant tuberculosis) remains a major public health concern, especially in high-burden countries like Nepal.
- Trial name
- NCT07003581
- Where
- Nepal
- Volunteers
- 183 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Carcinoma, Pancreatic Ductal
Organochlorine Concentration in Adipose Tissue and Pancreatic Adenocarcinoma
Pancreatic adenocarcinoma represents more than 90% of pancreatic neoplasms. Around 14000 new cases of pancreatic adenocarcinoma are being diagnosed each year in France and about 8.6% in Grand Est region.
- Trial name
- PESTIPAC (NCT04429490)
- Testing
- Adipose tissue sampling during surgery and urine sampling
- Where
- France
- Volunteers
- 56 people
- Sponsor
- CHU de Reims
Sleep Initiation and Maintenance Disorders
A Comparison of the Therapeutic Effect Between Head-point Acupuncture and Conventional Body Acupuncture on Insomnia
The investigators will conduct a single-center, and randomized controlled cases study. A total of 120 participants with insomnia will be enrolled.
- Trial name
- NCT04405427
- Testing
- head acupoints acupuncture, body acupoints acupuncture
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Chang Gung Memorial Hospital
Melanoma (Skin)
Study of Families With Melanoma
RATIONALE: A study that evaluates patients' lifestyle, skin, and blood and tissue samples may help doctors understand the risk factors for melanoma relapse.
- Trial name
- NCT00445783
- Testing
- gene expression analysis, mutation analysis, immunohistochemistry staining method
- Where
- United Kingdom
- Volunteers
- 3,700 people, healthy volunteers welcome
- Sponsor
- Leeds Cancer Centre at St. James's University Hospital
Cystic Fibrosis, Sleep Disorder
Case-control Study of Sleep Disorders in Children With Cystic Fibrosis
Our primary purpose is to compare the prevalence of sleep disorders in children aged 6 to 17 with cystic fibrosis versus controls with a Sleep disorder screening score, the SDSC.
- Trial name
- NCT04847882
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Strasbourg, France
Childhood Cancer Survivors
Pain and Sleep Disturbances in Children Living Beyond Cancer: A Case-Control Study
Children living beyond cancer (CBC) represent a unique and growing population of young people in need of long-term clinical support.
- Trial name
- NCT07120646
- Testing
- Questionnaire, actigraphy measurement and sleep diary
- Where
- 2 sites in Belgium
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Major Depressive Disorder (MDD), Treatment-resistant Depression (TRD)
Comparison of Efficacy of Minocyclin and Celecoxib as Adjunctive Treatment in Treatment Resistant Cases of Major Depressive Disorder
This randomized controlled study was conducted to compare the effectiveness of minocycline and celecoxib as add-on treatments in patients with treatment-resistant major depressive disorder.
- Trial name
- NCT07804979
- Testing
- Minocycline, Celecoxib
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Lahore General Hospital
Alzheimer Disease (AD), Healthy Controls Group - Age and Sex-matched
MIND Diet in Relation to Malnutrition and Depression in AD
The aim of this study was to examine the association between depression, malnutrition, and the Mediterranean-Dietary Approaches to Stop Hypertension Diet Intervention for Neurodegenerative Delay (MIND) diet in Alzheimer's disease…
- Trial name
- NCT07163923
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Magnet Controlled Capsule Endoscopy
Computer Assisted Quality-monitoring for Magnet-controlled Capsule Endoscopy: a Prospective Case-control Study.
During the past several years，MCE（magnet controlled endoscopy）has made great process in detecting lesions of gastric as well as screening.
- Trial name
- NCT04278196
- Testing
- AI-Box
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shandong University
Diabetes Mellitus, Biomarker
Study of Biomarkers in Diabetic Chronic Wounds
This study aims to discover, verify and evaluate the potential biomarkers with regard to the diagnosis, prognostic and/or prediction of diabetic chronic wounds.
- Conditions
- Diabetes Mellitus, Biomarker, Chronic Wound
- Trial name
- NCT05342740
- Testing
- collect whole blood, urine and stool samples
- Where
- China
- Volunteers
- 930 people, healthy volunteers welcome
- Sponsor
- Yibing Wang
Dementia With Lewy Bodies (DLB), Mild Cognitive Impairment (MCI)
Dementia With Lewy Bodies: Clinical Symptoms, Biomarkers and Progression
The goal of this observational study is to improve the detection of dementia with Lewy bodies (DLB) and its prodromal phases, as well as advancing our current understanding of biological mechanisms and therapeutic options.
- Conditions
- Dementia With Lewy Bodies (DLB), Mild Cognitive Impairment (MCI), Cognitively Unimpaired, Other Dementias
- Trial name
- Find-DLB (NCT07629349)
- Where
- Sweden
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Alzheimer Dementia (AD)
A Genetic Study for Alzheimer Dementia: Case-control Study
The purpose of this study is to find out the difference in genetic test results between Alzheimer's dementia patients and healthy subjects.
- Trial name
- NCT06330155
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- MinYoung Kim, MD, PhD
Chronic Constipation With Overflow, Encopresis With Constipation and Overflow Incontinence
Non-invasive Sacral Nerve Stimulation in Children and Adolescents With Chronic Constipation
The purpose of this study is to assess the efficacy of additional neuromodulation for treatment of chronic constipation in pediatric patients
- Conditions
- Chronic Constipation With Overflow, Encopresis With Constipation and Overflow Incontinence, Hirschprung's Disease, Anorectal Malformations
- Trial name
- NCT04710433
- Testing
- Non-invasive Neuromodulation, Medical and Behavioral Therapy
- Where
- Germany
- Volunteers
- 59 people
- Sponsor
- Friedrich-Alexander-Universität Erlangen-Nürnberg
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