Clinical trials: Case-control Study
Gingival Bleeding, Von Willebrand Diseases
Gingival Bleeding and Von Willebrand Disease Typ 2 and 3
Von Willebrand disease (VWD) is the most common inherent bleeding disorder resulting in prolonged bleeding time. Gingival bleeding is a frequently reported symptom of VWD.
- Trial name
- NCT03078595
- Where
- 2 sites in Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Goethe University
Fetal Growth Restriction, Antiphospholipid Syndrome
Antiphospholipid Antibodies and Fetal Growth Restriction
The Antiphospholipid Syndrome is an immune disease where the presence of antibodies directed against cell membrane phospholipids (antiphospholipid antibodies) can cause an hypercoagulable state that causes thrombosis and…
- Trial name
- NCT01538134
- Where
- Panama
- Volunteers
- 90 people
- Sponsor
- Saint Thomas Hospital, Panama
Obesity, Obesity, Childhood
Associations Between Obesity, Dental Caries, Erosive Tooth Wear and Periodontal Disease in Adolescents: A Case Control-study
Objectives To compare oral health (dental caries, periodontal status, and erosive tooth wear (ETW)), diet and oral hygiene habits between obese and normal weight adolescents, and to explore possible risk associations.
- Conditions
- Obesity, Obesity, Childhood, Tooth Wear, Tooth Erosion
- Trial name
- NCT05146557
- Testing
- Dental examination
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University Ghent
Chronic Rhinosinusitis Without Nasal Polyps, Chronic Rhinosinusitis (Diagnosis)
Pistacia Lentiscus Oil Nasal Drops for Preventing Recurrence of Chronic Rhinosinusitis
This retrospective, observational, case-control clinical study evaluated the safety and efficacy of nasal drops containing Pistacia lentiscus oil in preventing recurrence of chronic rhinosinusitis during long-term therapy.
- Trial name
- NCT07198607
- Testing
- Pistacia lentiscus Oil Nasal Drops (Bactorinol®), Isotonic Saline Nasal Wash
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Early Apical Peri-implantitis
Etiology of Early Apical Peri-implantitis
A case-control study was performed was performed following the STROBE statement from 1996 to 2016 including patients who were diagnosed with early apical peri-implantitis.
- Trial name
- EAP (NCT03523845)
- Testing
- Observational intervention to diagnose an early apical peri-implantitis
- Volunteers
- 46 people
- Sponsor
- University of Valencia
Cognitive Impairment
Can we Predict Chronic Homelessness?
Homeless men and women suffer more illness and sooner death compared to housed people. Among the homeless, there is a group that suffers more illness than others.
- Trial name
- NCT01775683
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Ottawa Hospital Research Institute
Cancer of Stomach, Cancer of the Esophagus
Nordic Gastric and Esophageal Tumor Study
This is a population-based case-control study in all 5 Nordic countries from 1994 onwards. Cases with esophageal or gastric cancer will be compared with 10 times as many population controls.
- Conditions
- Cancer of Stomach, Cancer of the Esophagus, Drug Use
- Trial name
- NordGETS (NCT05688761)
- Testing
- Proton pump inhibitor
- Where
- Sweden
- Volunteers
- 900,000 people
- Sponsor
- Karolinska Institutet
Assess PID Diagnosis Revision After CMEI Audit, Assess CMEI Recommendations' Impact on Respiratory Health
Domestic Environmental Exposure and Progression of ILD: An Exploratory Case-Control Study
The project titled "Domestic Environmental Exposure and Progression of Progressive or Stable Fibrosing Interstitial Lung Diseases: An Exploratory Case-Control Study" is a Category 3 study involving 60 patients with progressive or…
- Conditions
- Assess PID Diagnosis Revision After CMEI Audit, Assess CMEI Recommendations' Impact on Respiratory Health, ILD Progression and Exposure to Indoor Environnemental Risk, ILD Progression and Exposure to Outdoor Polluants
- Trial name
- EXPODOM-PID (NCT07457502)
- Testing
- Environmental audit of patient housing
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Ville de Paris
C.Surgical Procedure; Cardiac
A Case Control Study to Identify the Role of Epigenetic Regulation of Genes Responsible for Energy Metabolism and Mitochondrial Function in the Obesity Paradox in Cardiac Surgery
This is a prospective, single-centre case control comparison of expression of target genes responsible for energy utilisation, mitochondrial function and oxidative stress and levels of histone acetylation/ DNA methylation in…
- Trial name
- Ob-Card (NCT02908009)
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Leicester
Testicular Germ Cell Tumor
A Case-control Study to Assess the Association Between Environmental, Domestic and Occupational Exposures and the Risk of Testicular Germ Cell Tumor
The incidence of testicular germ cell tumors, the most common cancer in men aged 15 to 45 years, has doubled in France in 30 years.
- Trial name
- TESTIS (NCT02109926)
- Testing
- Phone interview and blood test
- Where
- 22 sites in France
- Volunteers
- 1,367 people, healthy volunteers welcome
- Sponsor
- Centre Leon Berard
Partial Edentulism, Tooth Disease
A Study of the Performance of Certain Prevail Implants Used in Short Fixed Cases
This prospective, randomized study evaluates the performance and crestal bone changes difference between the Osseotite Certain Prevail vs the non-lateralized design of the implant.
- Trial name
- RadioCity (NCT00723944)
- Testing
- Osseotite Certain Prevail, Osseotite Certain
- Where
- Germany
- Volunteers
- 102 people
- Sponsor
- ZimVie
Kaposiform Hemangioendothelioma
The Effect of Sirolimus on Immunizations During the Treatment of Kaposiform Hemangioendothelioma
To research and explore the antibody protection and immune memory after vaccination in children with KHE during sirolimus administration.
- Trial name
- NCT05351216
- Where
- China
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Myopia Progression
Factors Influencing Physiological Hyperopia in Children
The trend of myopia in children and its low age is a major social and public health problem in China. More seriously, retinopathy associated with high myopia has become the number one cause of irreversible blinding eye disease in…
- Trial name
- NCT06498947
- Testing
- This study was observational with no intervention.
- Where
- China
- Volunteers
- 1,006 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Indication for Modification of Patient Psychological Status
Psychological Profile of Dental Patients
The objective of this descriptive investigation was to evaluate the psychological profile of dental patients in three levels: global level, the dimensional level, and the discrete symptom level and to compare it with a control…
- Trial name
- NCT02792374
- Testing
- Psychological Measurement
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Talebian, Alireza, M.D.
Multiple Myeloma
Multiple Myeloma and Environmental Exposure to Pesticides in the French West Indies: A Population Based Case-control Study.
Multiple myeloma (MM) is a malignancy of plasma cells engaging in monoclonal immunoglobulin production. A strong presumption was established between exposure to pesticides and the risk of MM.
- Trial name
- MYELODOM (NCT04260490)
- Where
- 2 sites in Guadeloupe, Martinique
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Pancreas Adenocarcinoma, Small-cell Lung Cancer
Analyzing and Solving Exceptional Long-term Survivors in Solid Tumors With Poor Prognosis
This is a retrospective, exploratory, multi-center, translational, 3 cohorts case control matched study conducted in patients harboring a solid tumor with poor prognosis who presented a long-term (case) and standard (standard)…
- Conditions
- Pancreas Adenocarcinoma, Small-cell Lung Cancer, Glioblastoma, IDH-wildtype
- Trial name
- ROSALIND (NCT06160596)
- Testing
- Long term survival multimodal analysis
- Where
- France
- Volunteers
- 1,020 people
- Sponsor
- Cure 51
Carcinoma, Pancreatic Ductal
Organochlorine Concentration in Adipose Tissue and Pancreatic Adenocarcinoma
Pancreatic adenocarcinoma represents more than 90% of pancreatic neoplasms. Around 14000 new cases of pancreatic adenocarcinoma are being diagnosed each year in France and about 8.6% in Grand Est region.
- Trial name
- PESTIPAC (NCT04429490)
- Testing
- Adipose tissue sampling during surgery and urine sampling
- Where
- France
- Volunteers
- 56 people
- Sponsor
- CHU de Reims
Spinal Cord Injury, Acute
Systemic Hypothermia in Acute Cervical Spinal Cord Injury
This study is a prospective multi-center trial designed to determine the safety profile and efficacy of modest (33ºC) intravascular hypothermia following acute cervical (C1 to C8) Spinal Cord Injury (SCI).
- Trial name
- NCT02991690
- Testing
- Alsius Icy CoolGuard® Catheter
- Where
- 7 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of Miami
Covid19, Post-COVID / Long-COVID
Post-coronavirus Disease-2019 Fatigue
Background: COVID-19 is consistently spreading throughout the world, and the number of recovered patients is steadily increasing.
- Trial name
- NCT04851561
- Testing
- Cardiopulmonary stress test (CPET)
- Where
- Israel
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Epilepsy
Risk Factors of SUDEP
Numerous studies over the past decade have shown without any doubt that there is a higher mortality risk in patients with epilepsy than in the general population.
- Trial name
- PRERIES (NCT03074279)
- Testing
- Interview with a psychologist and self-reported questionnaires
- Where
- France
- Volunteers
- 408 people
- Sponsor
- University Hospital, Montpellier
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