Clinical trials: Case-control Study
Hyperemesis Gravidarum
Pregnancy Specific Nausea Questionnaire (PUQE) Translated and Tested in Norwegian
Nausea in early pregnancy (emesis gravidarum) is very common but most often self-limiting. Hyperemesis gravidarum; where nausea and vomiting is severe and protracted is potentially dangerous for the woman and her foetus and…
- Trial name
- PUQE-N (NCT01836835)
- Testing
- Pregnancy Unique Questionnaire of Emesis (PUQE), 24 hours self-reported nutritional intake form
- Where
- 2 sites in Norway
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Male Breast Cancer
Finasteride (MK-0906) and Male Breast Cancer - A Register-Based Nested Case-Control Study (MK-0906-162/2003.021).
The objective of this study is to investigate the potential association between finasteride (MK-0906) exposure and the development of breast cancer in men residing in Denmark, Sweden, Finland, and Norway from data in national…
- Trial name
- NCT01703520
- Volunteers
- 575,216 people
- Sponsor
- Organon and Co
Childhood Asthma With Acute Exacerbation
Antibiotic Treatment of Recurrent Episodes of Asthma in Children
Copsac has discovered that asthmatic exacerbations are as closely linked to bacterial as to viral infection. The current study will examine whether treatment of asthmatic exacerbations with macrolide antibiotics - in the abscence…
- Trial name
- AB-studie (NCT01233297)
- Testing
- Azithromycin
- Where
- 2 sites in Denmark
- Volunteers
- 70 people
- Sponsor
- Copenhagen Studies on Asthma in Childhood
Diabetes Mellitus
Investigation of Critically Ill Patients With Newly Diagnosed Diabetes
The purpose of this study is to investigate the clinical outcomes and glucose control metrics of critically ill patients with previously undiagnosed diabetes compared to those with known diabetes at the time of admission to the…
- Trial name
- NCT05256043
- Testing
- Diabetes Diagnosis
- Where
- United States
- Volunteers
- 1,777 people
- Sponsor
- Stamford Hospital
Biliary Tract Cancer
A Population-Based Case-Control Study of Biliary Tract Cancers in Shanghai, China
The key aims of this study include estimation of possible risk associated with a history of gallstones, bacterial infection for the biliary tract, other medical history, diet, use of tobacco and alcohol, obesity, reproductive…
- Trial name
- NCT00339560
- Where
- China
- Volunteers
- 2,624 people
- Sponsor
- National Cancer Institute (NCI)
Chronic Fatigue Syndrome in Adolescence, Postural Orthostatic Tachycardia Syndrome
POTS-CFS Study: Orthostatic Intolerance in the Context of Pediatric ME/CFS
Pilot-case-control study on exertion and orthostatic intolerance of adolescents with myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS) compared to age-matched healthy controls (HC).
- Conditions
- Chronic Fatigue Syndrome in Adolescence, Postural Orthostatic Tachycardia Syndrome, Orthostatic Intolerance
- Trial name
- POTS-CFS (NCT06054958)
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Community-acquired Pneumonia
Effectiveness of the PCV13 in Older Thai Adults
This is the matched 1:2 case-control study, prospectively collect case and control who are diagnosed with pneumococcal or non-pneumococcal community acquired pneumonia (CAP), accordingly from November 2023 through October 2024.
- Trial name
- NCT06279624
- Where
- Thailand
- Volunteers
- 825 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Rheumatic Disorder
Knowledge of Living Will in Patients With Rheumatic Diseases
The living will is a legal document derived from a communication and deliberation process, medical ethical aspect, currently regulated in Mexico by the General Health Law and the Health Law of Mexico City.
- Trial name
- NCT05676359
- Testing
- Health Assessment Questionnaire (HAQ), Depression, Anxiety and Stress Scale (DASS-21), Brief Resilient Coping Scale
- Where
- Mexico
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- National Institute of Medical Sciences and Nutrition, Salvador Zubiran
Obsessive-Compulsive Disorder
Function-metabolism Coupling in Decision-making Confidence Neural Network of Obsessive-compulsive Disorder
This study, a case-control study, aims to investigate the function-metabolism coupling in decision-making confidence neural network of obsessive-compulsive disorder.
- Trial name
- NCT05563935
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Multiple Sclerosis
Medical Marijuana and Its Effects on Motor Function in People With Multiple Sclerosis
Medical marijuana is commonly prescribed people with Multiple Sclerosis (MS) for symptom, e.g. spasticity and pain, management. Unfortunately not much is known about its effects outside the treatment for these 2 symptoms.
- Trial name
- NCT02898974
- Testing
- Medical Marijuana
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Colorado State University
Pain After Photorefractive Keratectomy, VAS Will be Used to Assess Pain Postoperative
Assessment of Safety and Efficacy of Gabapentin After Surface Ablation, a Case Control Experimental Study
The current study aims at assessing the efficacy and safety of oral Gabapentin alone versus Diclofenac Potassium drugs for postoperative analgesia in patients undergoing surface ablation.
- Trial name
- NCT06752486
- Testing
- Giving post photorefractive keratectomy for pain relief
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Research Institute of Ophthalmology, Egypt
Temporomandibular Disorder (TMD), Pain Threshold
Cervical Muscle Endurance and Pressure Pain Threshold in University Students With TMD: A Case-Control Study
Aim: This study aims to compare the static endurance of cervical region muscles, pressure pain thresholds of selected muscles of the stomatognathic system, and postural characteristics in young adults with and without…
- Trial name
- TMED-CME-PPT (NCT07407127)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Pregnancy Complications
Impact of Age at Conization on Obstetrical Outcome: A Case-Control Study
The maternity ward attached to the colposcopy clinic was also the obstetrical referral center for the region and carried out approximately 2500 deliveries per year.
- Trial name
- OBSTETRICON (NCT05765188)
- Testing
- loop electrosurgical excision procedure
- Where
- France
- Volunteers
- 115 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Partial Edentulism, Tooth Disease
A Study of Certain Prevail Implants Used for the Preservation of Crestal Bone in Short Fixed Bridge Cases.
This prospective, randomized study will evaluate the performance of the Osseotite Certain Prevail implant when compared to that of the non-lateralized version of the implant.
- Trial name
- Cliffhanger (NCT00728754)
- Testing
- Dental implant Osseotite Prevail, Dental implant Osseotite
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- ZimVie
Menstrual Cup, Intrauterine Device Migration
Shifting of Intrauterine Device and Use of the Menstrual Cup: Case-control Study
In France, 26% of women of childbearing age use an intrauterine device (IUD) containing copper or levonorgestrel as a method of contraception. Failures of IUD contraception are mainly due to shifting or expulsion of the IUD.
- Trial name
- CUP-DIU (NCT04782583)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 740 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Acute Kidney Injury
An Observational Case Control Study to Identify the Role of MV and MV Derived Micro-RNA in Post CArdiac Surgery AKI
Acute kidney injury (AKI) complicates over 25% of cardiac surgical procedures where it increases mortality up to fourfold. The incidence of AKI is increasing, the pathogenesis is poorly understood, current diagnostic tests lack…
- Trial name
- MaRACAS (NCT02315183)
- Testing
- This is an observational Study
- Where
- United Kingdom
- Volunteers
- 96 people
- Sponsor
- University of Leicester
Hirschsprung Disease, Febrile Urinary Tract Infection (Disorder)
Does Hirschsprung Disease Increase the Risk of Febrile Urinary Tract Infection in Children
Febrile urinary tract infection (FUTIs) are the most common bacterial infections in children under the age of 2 years. They represent 7% of children presenting with fever without a source.
- Trial name
- NCT04837963
- Where
- France
- Volunteers
- 630 people
- Sponsor
- University Hospital, Montpellier
Tracheal Stenosis
Observational Study for the Evaluation of Tracheal Stenosis in COVID-19 Patients
Define the actual incidence of tracheal stenosis in patients who underwent either prolonged intubation or tracheostomy and to compare incidence, clinical course and outcome between COVID-19 and non-COVID-19 patients.
- Trial name
- TS1 (NCT04686721)
- Testing
- Chest CT scan + baseline spirometry
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Istituto Clinico Humanitas
GERD
Image-Enhanced Endoscopy (IEE) for Diagnosis of Non-Erosive Reflux Disease
When treating persistent heartburn from gastroesophageal reflux disease (GERD) that does not respond to conventional treatment (a class of medications called proton pump inhibitors), it is important to be able to distinguish…
- Trial name
- NCT02629081
- Testing
- Controls & Cases
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Loren Laine
Amyotrophic Lateral Sclerosis, Motor Neuron Disease
Assessing Motor Neuron Disease Mechanisms by Threshold Tracking Transcranial Magnetic Stimulation and Magnetic Resonance Spectroscopy
Amyotrophic Lateral Sclerosis (ALS) is a motor neuron disease, which cases the death of neurons controlling the voluntary muscles.
- Conditions
- Amyotrophic Lateral Sclerosis, Motor Neuron Disease, Cortical Excitability
- Trial name
- NCT03664206
- Testing
- MRS, conventional TMS and treshold tracking TMS
- Where
- Denmark
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sándor Beniczky
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