Clinical trials: Cat Hypersensitivity
Rhinoconjunctivitis
Paediatric Safety Study in Cat-PAD
Study to Assess the Safety of Cat-PAD in Cat Allergic Paediatric Subjects
- Trial name
- NCT01921257
- Testing
- Cat-PAD
- Where
- 3 sites in Poland
- Volunteers
- 16 people
- Sponsor
- Circassia Limited
Cat Allergy, Cat Hypersensitivity
A Randomized Prospective Clinical Trial of Fel d 1 Peptide Immunotherapy
The goal of this study is to identify changes in cells that are related to the treatment with Cat-PAD (ToleroMune Cat).
- Trial name
- NCT02311413
- Testing
- Cat-PAD
- Where
- Canada
- Volunteers
- 39 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Allergic Rhinitis
Intralymphatic Immunotherapy (ILIT) for House Dust Mite, Cat, and Dog Allergen in Allergic Rhinitis Patients
We will perform double-blinded placebo-controlled randomized clinical trial which evaluates the efficacy and safety of allergen-specific intralymphatic immunotherapy (ILIT) for allergens including Dermatophagoides farinae (Df)…
- Trial name
- ILIT (NCT02269566)
- Testing
- HollisterStier, Normal saline
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Gachon University Gil Medical Center
Hypersensitivity
Skin Tests in Cat Allergic Patients With Cat Dander Samples Obtained Before and After Vaccinating the Cat
Determination of allergenicity of cat dander samples obtained before and after vaccinating the cat
- Trial name
- NCT02667379
- Testing
- Diagnostic skin testing
- Where
- Switzerland
- Volunteers
- 7 people
- Sponsor
- University of Zurich
Allergic Asthma
Analysis of Fel d 1-specific T Cells After Airway Allergen Challenge in Asthma
Cat allergies are a major trigger of asthma. Therapies are being developed to control the allergic response to cats. We are interested in measuring a type of white blood cell which is linked to cat allergies, which will help us…
- Trial name
- NCT01612715
- Testing
- Segmental Allergen Challenge
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- Hamilton Health Sciences Corporation
Allergic Asthma, Allergy
Validation of Strasbourg Environmental Exposure Chamber ALYATEC in Cat Allergic Subjects With Asthma
This is a randomized, double blind, cross-over study designed to determine the concentration of airborne cat allergen inducing bronchial response in asthmatic subjects allergic to cat, during allergen exposures in the Alyatec…
- Conditions
- Allergic Asthma, Allergy, Allergy to Cats
- Trial name
- NCT04678063
- Testing
- Exposure to dose A and dose B of cat allergen, Exposure to a single dose of cat allergen
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Alyatec
Cat Allergy
Safety of Cat-PAD to Treat Cat Allergy in Cat Allergic Subjects With Controlled Asthma
Cat allergy is an increasingly prevalent condition, affecting 10-15% of patients with allergic rhinoconjunctivitis and/or asthma.
- Trial name
- NCT00867906
- Testing
- Cat-PAD
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Circassia Limited
Asthma, Allergy
Efficacy of Air Cleaners in Asthmatics Allergic to Cat in ALYATEC Environmental Exposure Chamber
The aim of this study is to determine the efficacy of Rowenta® "Intense Pure Air XL" air cleaner on the early and late bronchial response, in cat-allergic asthmatic patients during an allergen exposure in ALYATEC environmental…
- Trial name
- NCT03928561
- Testing
- Active intense Pure Air XL air cleaner
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Alyatec
Allergic Rhinitis
The Effect of Omalizumab on Responses to Cat Allergen Challenge
This research is being done to study the effects of the drug omalizumab (Xolair) in people with cat allergies. The investigators will use omalizumab to study changes in the cells in the nose, skin and blood that cause allergies.
- Trial name
- NCT00604786
- Testing
- omalizumab
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Johns Hopkins University
Hypersensitivity
Methodological Study to Compare the Effect of Different Methods of Measuring Cat Allergy Symptoms in Patients That Have Immunized Their Cats With FEL-CMV.
In this Project we will monitor the symptoms of cat allergic participants who live together with a cat which is immunized with FEL-CMV using the novel symptom recording method "HypoScore", a General weekly symptom score, and a…
- Trial name
- NCT03089788
- Testing
- Home-based test, Skin test
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Cat Allergy, Rhinoconjunctivitis
An Optional Two Year Follow Up Study to Study CP005A
Cat allergy is an increasingly prevalent condition affecting 10-15% of patients with allergic rhinoconjunctivitis and/or asthma.
- Trial name
- NCT01604018
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- Circassia Limited
Cat Allergy
Effectiveness of Cat-PAD to Treat Cat Allergy in Cat Allergic Subjects
Cat allergy is an increasingly prevalent condition, affecting 10-15% of patients with allergic rhinoconjunctivitis and/or asthma.
- Trial name
- NCT00729508
- Testing
- Cat-PAD
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Circassia Limited
Cat Induced Allergic Rhinitis
A Single-Center, Randomized, Double-Blind, Placebo-Controlled, Two-Way Crossover Study Designed to Evaluate the Efficacy of Fexofenadine HCl 180 mg for Preventing and Controlling Cat Allergy Symptoms
This is a single-center, prospective, randomized, double-blind, placebo-controlled, two-way crossover study. A live cat challenge model will be used for exposing subjects to Fel d1.
- Trial name
- NCT00637884
- Testing
- Fexofenadine HCl
- Volunteers
- 70 people
- Sponsor
- Sanofi
Asthma
A Study of Omalizumab in Preventing Bronchoconstriction Following Environmental Cat Dander Exposure in Patients With Cat Dander-induced Asthma
This was a 3-center, randomized, double-blind, parallel-group, placebo-controlled study with a 16-week treatment phase to determine whether subcutaneous omalizumab, compared with placebo, reduces the degree of bronchoconstriction…
- Trial name
- AERO (NCT00495612)
- Testing
- Omalizumab
- Volunteers
- 69 people
- Sponsor
- Genentech, Inc.
Rhinoconjunctivitis
Phase II HDM-SPIRE Safety and Efficacy Study
The purpose of this study is to compare the treatment effect of three treatment regimens of HDM-SPIRE vs placebo and to evaluates the treatment effect of HDM-SPIRE on symptoms, rescue medication usage, Quality of Life and Sleep…
- Trial name
- NCT02150343
- Testing
- HDM-SPIRE
- Where
- 98 sites in United States, Canada and 6 more
- Volunteers
- 715 people
- Sponsor
- Circassia Limited
Allergy and Immunology
Escalating Single Dose Study of Epsi- Gam in Healthy Normal Subjects
This is a single-center, randomized, double-blind, placebo-controlled, single-dose, dose- escalation study in otherwise healthy cat-, dust mite-, or Bermuda grass-allergic male and female subjects.
- Trial name
- NCT02559258
- Where
- Australia
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Tunitas Therapeutics, Inc.
Asthma, Allergic
Anakinra as a Rescue Treatment for Allergic Inflammation
Participants with mild asthma who are sensitized to either house dust mite or cat hair allergen will undergo nasal instillation of the allergen to elicit nasal allergy symptoms.
- Trial name
- NCT04035109
- Testing
- Anakinra, House dust mite allergen, Cat hair allergen
- Sponsor
- University of North Carolina, Chapel Hill
Allergic Conjunctivitis
A Study to Evaluate the Efficacy and Safety of Fel d 1 Monoclonal Antibodies in Adult and Pediatric Participants With Allergic Conjunctivitis Due to Cat Allergy
This study is researching two experimental medicines, freneslerbart and mevonlerbart. Freneslerbart and mevonlerbart can be given alone or together. When given together, the medicine is called "REGN-2Cat".
- Trial name
- NCT07675811
- Testing
- REGN-2Cat, Freneslerbart, Mevonlerbart
- Where
- United States
- Volunteers
- 570 people
- Sponsor
- Regeneron Pharmaceuticals
Allergy
LYmph Node eXamination in Cat Allergen Immunotherapy
Sixteen eligible cat-allergic participants will be accrued in the study. Eight participants who have been on subcutaneous immunotherapy (SCIT) at maintenance dosing for at least 1 year will be assigned to the SCIT cohort, and 8…
- Trial name
- LYNX (NCT07447869)
- Testing
- Intradermal cat allergen challenge
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cat Allergy
Safety of Cat-PAD in Cat Allergic Subjects
Cat allergy is an increasingly prevalent condition, affecting 10-15% of patients with allergic rhinoconjunctivitis and/or asthma.
- Trial name
- NCT00685711
- Testing
- Cat-PAD
- Where
- Germany
- Volunteers
- 88 people
- Sponsor
- Circassia Limited