Clinical trials: Cat Hypersensitivity
Allergic Rhinitis
Diesel Exhaust Particles and Leukotriene Production
The purpose of this study is to measure the effects of allergens and/or diesel exhaust particles in the nose to learn more about allergic responses in individuals with cat allergic rhinitis.
- Trial name
- NCT00915447
- Where
- United States
- Sponsor
- University of California, Los Angeles
Allergy to Cats
Crossover Study of Zafirlukast in Preventing Allergen-induced Signs and Symptoms in Response to Cat Dander Challenge
The goal of this clinical trial is to test the hypothesis that pre-treatment with a nasal dose of Zafirlukast works well in blocking the signs and symptoms of cat dander in patients sensitive to cat dander.
- Trial name
- NCT06069063
- Testing
- Zafirlukast
- Volunteers
- 12 people
- Sponsor
- Allergy & Asthma Medical Group & Research Center
Cat Allergy
Exposure Chamber Trial With Cat Immunotherapy
The main purpose of this trial is to investigate if any of three different doses of cat hair immunotherapy is safe for treatment of cat allergic patients.
- Trial name
- NCT00987909
- Testing
- Specific allergen immunotherapy
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- ALK-Abelló A/S
Cat Allergy, Mild Asthma
Study in Cat-Allergic Patients With Asthma to Evaluate the Efficacy of a Single Dose of REGN1908-1909 to Reduce Bronchoconstriction Upon Cat Allergen Challenge
The primary objective is to evaluate the prophylactic efficacy of REGN1908-1909 (anti-Fel d 1) administered as a single dose on day 1 in cat-allergic asthmatic patients not living with a cat in the prevention of a Controlled Cat…
- Trial name
- NCT03838731
- Testing
- REGN1908-1909
- Where
- France
- Volunteers
- 56 people
- Sponsor
- Regeneron Pharmaceuticals
Allergic Conjunctivitis
Study of Two Marketed Ocular Anti-Allergy Medications in Subjects With Allergic Conjunctivitis
The purpose of this study is to compare the effects of two marked ocular anti-allergy medications in cat sensitive subjects with allergic conjunctivitis.
- Trial name
- NCT00534794
- Testing
- Elestat, Pataday
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Merck Sharp & Dohme LLC
Allergy to Cat Dander
Evaluation of Safety, Tolerability, Immunogenicity and Efficacy of a Novel Method in Specific Immunotherapy in Cat Allergic Patients: a Placebo Controlled Trial
This study is placebo controlled, double blind, randomised, two arm dose escalation of a new product for specific immunotherapy in cat allergic patients
- Trial name
- IVN-CAT-001B (NCT00718679)
- Testing
- IVN201
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University of Zurich
Allergy
Observational Analysis of T Cell Responses to SPIREs for Multiple Allergens in Subjects With Allergy in North America
This is a research study intending to look at the response of a specific type of allergy cells in the blood (called T cells) to a a type of immunotherapy product known as SPIREs (Synthetic Peptide Immuno-Regulatory Epitopes)…
- Trial name
- NCT02601690
- Testing
- Blood Sampling
- Where
- 2 sites in United States
- Volunteers
- 199 people
- Sponsor
- Adiga Life Sciences, Inc.
Cat Allergy, Rhinoconjunctivitis
Cat-PAD Follow on Study
Cat allergy is an increasingly prevalent condition, affecting 10-15% of patients with allergic rhinoconjunctivitis and/or asthma.
- Trial name
- NCT01272323
- Testing
- Cat-PAD Dose 1, Cat-PAD Dose 2
- Where
- Canada
- Volunteers
- 170 people
- Sponsor
- Circassia Limited
Cat Allergy, Cat Hypersensitivity
Anti-TSLP (AMG 157) Plus Antigen-Specific Immunotherapy for Induction of Tolerance in Individuals With Cat Allergy
This trial will test whether a novel therapeutic approach, cat immunotherapy combined with an investigational new drug called MEDI9929/AMG 157 (an anti-TSLP [thymic stromal lymphopoietin] antibody being co-developed by Amgen and…
- Trial name
- NCT02237196
- Testing
- AMG 157, Cat Immunotherapy
- Where
- 9 sites in United States
- Volunteers
- 121 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Perennial Allergic Rhinitis
The Effect of Nasal Carbon Dioxide (CO2) on Nasal Congestion in Subjects With Perennial Allergic Rhinitis
The purpose of this study is to evaluate the effect of nasal CO2 on nasal congestion and other symptoms related to Perennial Allergic Rhinitis.
- Trial name
- NCT00638755
- Testing
- Nasal Carbon Dioxide
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Capnia, Inc.
Allergy to Cats, Allergic Rhinoconjunctivitis
Effect of holoBLG on Cat Allergic Patients
The aim of the study is to investigate the antigen-unspecific effect of a 3 months supplementation with a food for special medical purposes (FSMP) in form of a lozenge containing beta-lactoglobulin (BLG), iron, retinoic acid…
- Trial name
- NCT05455749
- Testing
- holoBLG
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- Allergy Therapeutics
Allergic Rhinitis
Allergenic Extract Standardized Cat Hair AP in an Allergic Rhinitis Model.
The goal of this study is to learn if a cat allergen extract known as Allergenic Extract Standardized Cat Hair Acetone Precipitated (AP Cat) can induce allergic rhinitis (AR) in a nasal allergen challenge model in cat-allergic…
- Trial name
- AP-CAT (NCT06828484)
- Testing
- Allergenic Extract Standardized Cat Hair Acetone-Precipitated (AP)
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Queen's University
Allergic Asthma, Allergy to Cats
Airway Immune Response to Allergens (Use Lay Language Here)
Most asthma is allergic in origin. The purpose of this study is to better understand the airway immune response to inhaled allergens in order to identify factors that promote asthma.
- Conditions
- Allergic Asthma, Allergy to Cats, Allergy to Dust Mites, Allergic Rhinitis
- Trial name
- NCT04619017
- Testing
- Segmental allergen challenge
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- JOSALYN CHO
Allergy, Allergic Asthma
abioSCOPE IgE Assay to Aid in the Diagnosis of Allergies
This is a multicenter, prospective, observational study designed to determine the clinical sensitivity and specificity of the Abionic IVD CAPSULE Allergic Asthma panel performed on Abionic's abioSCOPE device using K3-EDTA…
- Conditions
- Allergy, Allergic Asthma, Allergy to Cats, Allergy to House Dust
- Trial name
- NCT04442932
- Testing
- Blood Collection
- Where
- 5 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Abionic SA
Cat Allergy (Disorder)
Biological Potency of the Cat Epithelial Allergenic Extracts
The primary objective of this clinical trial is to quantify the loss of in vivo biological potency of a depigmented polymerized (DPP) allergenic cat epithelial extract versus the native allergenic extract (N).
- Trial name
- NCT01740024
- Testing
- 1 (Dose Response Skin Prick Tests)
- Where
- 2 sites in Spain
- Volunteers
- 35 people
- Sponsor
- Laboratorios Leti, S.L.
Immediate Hypersensitivity
Comparison Between spIgE and Skin Prick Test of Local and Imported Aeroallergens
The prevalence of Allergic rhinitis(AR) and asthma was increased world wide. In 1998, ISAAC found that prevalence of AR and asthma inThailand was in moderately high group.
- Trial name
- NCT02561390
- Testing
- Skin prick test, specific IgE measurement
- Where
- Thailand
- Volunteers
- 84 people
- Sponsor
- Mahidol University
Cat Allergy
Evaluation of a New Self-assessed, Home-based Symptom Score in Cat Allergic Patients
In the last decades the prevalence of allergies has reached epidemic proportions. 10 to 15% of the population suffers from cat allergy.
- Trial name
- HypoScore-2 (NCT02959073)
- Testing
- Symptom Recording
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Rhinitis, Allergic
Ability of a Cat Food to Reduce Respiratory Symptoms in Cat Allergic Patients
Cat allergy is the most common animal allergy, affecting approximately 1 in 5 adults worldwide. The prevalence of allergy to furry animals is increasing, and cat allergy is a major risk factor for the development of asthma and…
- Trial name
- CATS (NCT05656482)
- Testing
- Cats fed with PRO PLAN® LIVECLEAT®
- Where
- France
- Volunteers
- 50 people
- Sponsor
- MASK-air SAS
Allergic Rhinitis, Rhinoconjunctivitis
Red Maple Trials Cat Allergen Natural Exposure Chamber Validation in Cat-allergic Subjects
To assess the reproducibility of the allergic response in the cat allergic subjects, measured as the change from baseline of the Total Nasal Symptom Score (TNSS) on the two challenge days.
- Conditions
- Allergic Rhinitis, Rhinoconjunctivitis, Exposure
- Trial name
- NEC (NCT03414801)
- Testing
- Allergen Exposure
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Red Maple Trials Inc.
Cat Allergy
The Effects of Omalizumab (Anti-IgE) on the Late-phase Response to Nasal Allergen Challenge
This research is being done to study the effects of the drug omalizumab (Xolair) in people with cat allergies. The investigators will use omalizumab to study changes in the cells in the nose, cells in the blood and cells in the…
- Trial name
- NCT01003301
- Testing
- Omalizumab
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University