Clinical trials: Cataract, completed
Aphakia, Astigmatism
Post Market Clinical Follow-up (PMCF) Study of Clareon Vivity & Clareon PanOptix
The purpose of this Post-Market Clinical Follow-up study is to describe the long-term safety and performance of the Clareon Vivity and Vivity Toric and Clareon PanOptix and PanOptix Toric IOLs.
- Conditions
- Aphakia, Astigmatism, Presbyopia
- Trial name
- NCT05796453
- Testing
- Clareon Vivity IOL - Non Toric, Clareon Vivity IOL - Toric, Clareon PanOptix Trifocal IOL - Non Toric
- Where
- 7 sites in United States, Puerto Rico
- Volunteers
- 470 people
- Sponsor
- Alcon Research
Cataract Surgery
Efficacy and Safety of Bromfenac Ophthalmic Solution
This is a safety and efficacy study of bromfenac ophthalmic solution
- Trial name
- NCT00585975
- Testing
- bromfenac ophthalmic solution
- Where
- United States
- Volunteers
- 568 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Nuclear Cataract
Phacoemulsification at High IOP and Physiologic IOP: Impact on Anterior and Posterior Segment Physiology
The purpose of this study is to investigate the anterior and posterior structure and functional changes and vascular alterations when performing phacoemulsification at high IOP vs low, more physiological IOP using Centurion®…
- Trial name
- NCT05765201
- Testing
- High IOP, Low IOP
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Matthew Rauen
Cataract and IOL Surgery
Comparing Visual Outcomes in Matched Patients Receiving a Low Cylinder Power Toric IOL or a Non-toric IOL
The purpose of the study is to determine if visual function is improved with implantation of a low-cylinder toric intraocular lens, relative to a non-toric intraocular lens.
- Trial name
- NCT06717607
- Testing
- low cylinder toric IOL, non-toric IOL implantation
- Where
- Norway
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Ifocus Oyeklinikk
Cataract, Presbyopia
Visual Results of the Acrysof IQ Vivity Toric Extended Vision Intraocular Lens
The main goal of this study is to evaluate real-world visual outcomes, rotational stability, and patient reported visual disturbances with a non-diffractive extended vision presbyopia and astigmatism correcting intraocular lens…
- Conditions
- Cataract, Presbyopia, Corneal Astigmatism
- Trial name
- NCT04652037
- Testing
- Acrysof IQ Vivity Toric Extended Vision Intraocular Lens Implantation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Cataract
Anesthetic and Dilating Gel for Cataract Surgery
To prepare the eye for cataract surgery, drugs must be given to the eye to allow for surgery to take place. Traditionally, dilating drops and drops containing NSAIDs (to control inflammation) are given to the patient well in…
- Trial name
- NCT00335400
- Testing
- Anesthetic Dilating Gel
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Queen's University
Cataract
Yellow Versus White Study
Blue-light-filtering IOLs are implanted increasingly often in cataract surgery. Several studies examined the effect of blue-light-filters on contrast and colour vision. However, the study outcomes were varying.
- Trial name
- YeWhi (NCT00612781)
- Testing
- cataract surgery (Hoya AF-1 [UY] YA-60BB), cataract surgery (Hoya AF-1 [UV] VA-60BB lens)
- Where
- Austria
- Volunteers
- 24 people
- Sponsor
- Hospital Hietzing
Idiopathic Epiretinal Membrane, Cataract
Surgical Removal of Idiopathic Epiretinal Membrane With and Without the Assistance of Indocyanine Green.
It was the aim of the present study to prospectively compare the functional and morphological outcome of idiopathic epiretinal membrane surgery with and without the assistance of Indocyanine green (ICG).
- Trial name
- NCT00376857
- Testing
- Surgery with and without the aid of Indocyanine Green (ICG)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University of Regensburg
Aphakia, Presbyopia
Clareon PanOptix Pro vs. Clareon PanOptix - Study B
The purpose of this study is to evaluate the safety and effectiveness of Clareon™ PanOptix™ Pro Trifocal Intraocular Lens (IOL) compared to Clareon™ PanOptix™ Trifocal IOL.
- Trial name
- NCT06401551
- Testing
- CPO Pro IOL, CPO IOL, Cataract Surgery
- Where
- 8 sites in United States
- Volunteers
- 71 people
- Sponsor
- Alcon Research
Cataract, Lens Opacities
Clinical Investigation of the Multifocal IOL POD F GF in Cataracteous Eyes
To evaluate effectiveness and safety of the POD F GF Intraocular Lens (IOL) when implanted to replace the natural lens following cataract removal
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- NCT04699266
- Testing
- Assigned Intervention (POD F GF)
- Where
- Japan
- Volunteers
- 23 people
- Sponsor
- Beaver-Visitec International, Inc.
to Compare the Effect of Two Types of IOLs, on the Incidence of Cystoid Macular Edema
The Effect of a Blue Light Filtering IOL
To compare the effect on blood retinal barrier disruption 3 and 12 months after implantation of either a blue light filtering intraocular lens(blue-filtering IOL) or an ultraviolet light filtering intraocular lens(UV-filtering…
- Conditions
- to Compare the Effect of Two Types of IOLs, on the Incidence of Cystoid Macular Edema, After Cataract Surgery
- Trial name
- NCT00571831
- Testing
- intraocular lens implantation
- Where
- Japan
- Volunteers
- 50 people
- Sponsor
- Showa University
Cataract, Nursing Caries
Effects of Music and Stress Ball Application on Patients During Cataract Surgery
Cataract is one of the leading causes of preventable blindness in the world and in Türkiye. Cataract surgery is one of the most frequently performed and most reliable surgeries for eye diseases.
- Trial name
- NCT06555770
- Testing
- Music intervention, Stress ball
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Cataract
Spherical Aberration and Contrast Sensitivity Function in Eyes Implanted With Spherical and Aspheric Intraocular Lenses: A Clinical Trial
Aspheric intraocular lenses can effectively reduce higher-order aberrations and improve contrast sensitivity function after cataract surgery.
- Trial name
- NCT01028872
- Testing
- Intraocular lens
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Posterior Capsule Opacification, Cataract
Posterior Capsule Opacification and Frequency of Nd:YAG Treatment and of Two IOLs: Hoya iMics Y-60H vs. Bausch&Lomb MI60 (MIMI)
Age-related cataract is the main cause of impaired vision in the elderly population worldwide. The only treatment that can restore functional visual ability is cataract surgery where the opacified crystalline lens is removed by…
- Trial name
- NCT01786356
- Testing
- HOYA iMics Y-60H, B&L MI60
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Inflammation, Cataracts
The Efficacy and Safety of IBI-10090 for the Treatment of Inflammation Associated With Cataract Surgery
The purpose of this study is to determine whether IBI-10090 injection is effective in the treatment of inflammation associated with cataract surgery.
- Trial name
- NCT02006888
- Testing
- IBI-10090
- Where
- United States
- Volunteers
- 394 people
- Sponsor
- ICON Bioscience Inc
Cataract, Pseudoexfoliation Syndrome
Bromfenac to Reduce Inflammation in Patients With Pseudoexfoliation Syndrome After Cataract Surgery
OBJECTIVE To evaluate the efficacy of bromfenac ophthalmic solution 0.09% for reducing postoperative inflammation in eyes with pseudoexfoliation syndrome (PEX) undergoing cataract surgery and receiving standard postoperative eye…
- Trial name
- REPEX (NCT02137161)
- Testing
- Dexamethasone+Tobramycin eye drop, Bromfenac eye drop
- Where
- Italy
- Volunteers
- 62 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Pediatric Cataract, Congenital Cataract
Toric Intraocular Lens Implantation for Pediatric Aphakia
Here, we conducted a nonrandomized clinical trial aims to evaluate and compare the prognosis of visual function in children of these two types of IOL implantation over a three-year postoperative period.
- Trial name
- NCT07088796
- Testing
- Toric IOL implantation, Non-toric IOL implantation
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Cataract, Presbyopia
Clinical Investigation of a Small Aperture Extended Depth of Focus Intraocular Lens in Patients With Complex Corneas
The objective of this study is to evaluate the clinical outcomes of the IC-8 IOL implanted in patients with complex corneas after crystalline lens removal.
- Conditions
- Cataract, Presbyopia, Irregular Astigmatism
- Trial name
- NCT05574270
- Testing
- IC-8 Intraocular Lens (IOL)
- Where
- 2 sites in Philippines, Singapore
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AcuFocus, Inc.
Demodex Infestation, Demodicosis
Evaluation of Treatment Option for Demodicosis in Patients Undergoing Cataract Surgery
Demodex blepharitis is a prevalent cause of comorbid infection among individuals undergoing cataract surgery. Several complications may arise in the postsurgical period from Staphylococcus or Streptococcus co-infections, as…
- Conditions
- Demodex Infestation, Demodicosis, Cataract
- Trial name
- NCT04204954
- Testing
- Ciprofloxacin Ophthalmic Ointment 0.3%, Blephaclean
- Where
- Mexico
- Volunteers
- 160 people
- Sponsor
- Hospital de La Luz
Cataract
Clinical Outcomes After Implantation of a Monofocal Hydrophobic IOL, Bi-Flex 877PAY With POB-MA Preloaded Injector
The purpose of our investigation is to retrospectively assess visual outcomes, refractive stability, safety features of the lens and the incidence of developing PCO (posterior capsular opacification) in a 12-month period…
- Trial name
- NCT06469541
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Medicontur Medical Engineering Ltd