Clinical trials: Cataract Extraction, open to volunteers
Cataract and IOL Surgery, IOL Implantation
Head-to-Head Comparison of Five Enhanced Depth of Focus IOLs and One Monofocal IOL
Study Goal The goal of this clinical trial is to compare how well four different types of artificial lenses (called intraocular lenses or IOLs) help people see after cataract surgery.
- Conditions
- Cataract and IOL Surgery, IOL Implantation, Presbyopia Correction, Extended Depth of Focus
- Trial name
- AKA-Reports (NCT07051720)
- Testing
- Bilateral implantation of CT ASPHINA 409M, Bilateral implantation of TECNIS Eyhance ICB00, Bilateral implantation of AcrySof® IQ Vivity®
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- Augenklinik Ahaus G + H GmbH & Co. KG
Glaucoma
Pilocarpine Use After Kahook Goniotomy
The goal of this study is to determine whether using pilocarpine provides added benefit to the success of combined cataract + Kahook Dual Blade (KDB) surgery.
- Trial name
- PAACK (NCT03933631)
- Testing
- Pilocarpine, Prednisolone, Ofloxacin
- Where
- 2 sites in United States
- Volunteers
- 142 people
- Sponsor
- Montefiore Medical Center
Cataract Bilateral
"Comparative Study of High-frequency Pulsed Vacuum Technology Versus Phacoemulsification for Cataract Surgery
Cataracts are cloudings of the lens, primarily due to aging. Surgery is the primary treatment for cataracts. The most commonly used surgical technique is phacoemulsification, which involves fragmenting the lens using a…
- Trial name
- PULSEM (NCT07074431)
- Testing
- Eye 1 by the Technique by high-frequency pulsed vacuum technology, Eye 2 : Surgery byTechnique by high-frequency pulsed vacuum technology
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Clinique Victor Pauchet
Cataract Surgery, Ocular Infections
Efficacy of EPD-09-25 for Eyelid Hygiene Before and After Eye Surgery.
This is an interventional, open-label, two-arms clinical trial, randomized 1:1 (EPD treatment or no eyelid hygiene treatment) in patients scheduled for eye surgery (cataract surgery).
- Trial name
- NCT07418333
- Testing
- EPD Eyelid wipes
- Volunteers
- 100 people
- Sponsor
- VISUfarma SpA
Cataract Surgery Deneyimi, Cataract Surgery
Katarak Surgery and Care
Although cataract surgery is an effective treatment method for improving visual function, it is important to evaluate the quality of life, daily living activities, independence level and psychosocial well-being of patients in the…
- Trial name
- NCT07807761
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Intraocular Implants, Extended Depth of Focus
Quality of Vision After Implantation of EDOF Implants Versus Monofocal Implants in Patients Who Underwent Epiretinal Membrane and Cataract Surgery
Phacoexistence, the first surgical procedure performed in France, naturally raises the question of lens replacement. In recent years, the choice of intraocular lenses has expanded considerably.
- Trial name
- MACAEDOF (NCT07789249)
- Testing
- Questionnaires, Intermediate visual acuity, Optical coherence tomography
- Where
- 3 sites in France
- Volunteers
- 100 people
- Sponsor
- Almaviva Sante
Cataract, Fuchs Endothelial Corneal Dystrophy
Partial Range Of Field IOLs in DMEK-Enabled Procedures
Study Overview This study aims to evaluate the visual outcomes, quality of vision, and patient satisfaction after receiving an extended range PRoF intraocular lens (IOL) during triple Descemet Membrane Endothelial Keratoplasty…
- Trial name
- PROFIDE (NCT07441616)
- Testing
- combined cataract and lamellar endothelial keratoplasty
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Universitair Ziekenhuis Brussel
Cataract, Dry Eye
Evaluation of the Effectiveness of Three Tear Substitute Formulations in Postoperative Discomfort After Cataract Surgery
The primary objective of this study is the assessment of three tear substitute formulations in terms of postoperative discomfort following cataract extraction surgery by means of phacoemulsification and intraocular lens…
- Trial name
- DRY-CAT (NCT07581548)
- Testing
- Sodium Hyaluronate 0.15% and Dexpanthenol 2% drops (Hylopan max), Sodium Hyaluronate 0.15% and Trehalose 3% drops (Thealoz duo), Sodium Hyaluronate 0.2% and Amino acids drops (Helenvision ultra)
- Where
- Greece
- Volunteers
- 300 people
- Sponsor
- Democritus University of Thrace
Light Adjustable Lens, Objective Depth of Focus
Objective Depth-of-Focus Changes During Light Adjustable Lens UV Adjustments
This observational pilot study will examine how a person's vision changes during the routine adjustment and finalization of a Light Adjustable Lens (LAL) after surgery.
- Trial name
- NCT07868003
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Clarity Eye Institute
OAG - Open-Angle Glaucoma
Clinical Trial to Evaluate the Safety and Effectiveness of a Canaloplasty Device in Subjects With Open-Angle Glaucoma
Clinical Trial to Evaluate the Safety and Effectiveness of a Canaloplasty Device in Subjects with Open-Angle Glaucoma
- Trial name
- NCT05696561
- Testing
- Canaloplasty Device
- Where
- 3 sites in Chile, Costa Rica and 1 more
- Volunteers
- 70 people
- Sponsor
- New World Medical, Inc.
Dry Eye Disease, Cataract
The Pattern of Dry Eye Disease After Cataract Surgery
This study is designed to explore dry eye disease (DED) pattern: ocular surface, corneal morphological changes, patients' subjective assessment of DED and their correlations with ocular surface inflammation, pain biomarkers after…
- Conditions
- Dry Eye Disease, Cataract, Ocular Surface Disease
- Trial name
- NCT06298890
- Testing
- Artificial tears (sodium hyaluronate 0.2%)
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Lithuanian University of Health Sciences
Cataract Bilateral, Bilateral Cataracts
Medico-economic Evaluation of Immediately Sequential Bilateral Cataract Surgery Compared With Delayed Sequential Cataract Surgery in France
Cataracts are defined as opacification of all or part of the crystalline lens, resulting in reduced vision. It is a common disease in France, affecting more than one in five people over the age of 65, and almost two in three over…
- Conditions
- Cataract Bilateral, Bilateral Cataracts, Bilateral Cataract
- Trial name
- SIMCAT (NCT06737562)
- Testing
- Immediatly sequential bilateral cataract surgery, Delayed sequential bilateral cataract surgery
- Where
- 4 sites in France
- Volunteers
- 242 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Cataract
A Study on the Application of Smart Bed-Exit Alert Assistive Devices for Detecting Preoperative Bed Exits in Ophthalmic Surgery Patients in the Operating Room
This prospective, randomized interventional study aims to evaluate the effectiveness of a smart bed-exit alert system for patients undergoing cataract surgery during the preoperative waiting period.
- Trial name
- NCT07693829
- Testing
- Smart Bed-Exit Alert System
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Dry Eye, Dry Eye Disease (DED)
Temporary Tear Duct Filling With Hyaluronic Acid Gel and Assessment of Dry Eye Disease (DED) After Bilateral Cataract Surgery
Dry eye disease can occur or worsen after cataract surgery and may cause ocular discomfort and reduced visual quality. Standard treatment commonly includes artificial tear eye drops, which provide temporary lubrication.
- Conditions
- Dry Eye, Dry Eye Disease (DED), Dry Eye Sensation After Cataract Surgery
- Trial name
- TANAMI (NCT07809022)
- Testing
- LACRIFILL® Canalicular Gel administration
- Where
- Austria
- Volunteers
- 25 people
- Sponsor
- Medical University of Vienna
Corneal Astigmatism, Cataract
Effectiveness, Stability and Influence Factors of Femtosecond Laser Assisted Cataract Surgery
What is this study about? This study looks at whether a laser procedure called femtosecond laser-assisted arcuate keratotomy (FSAK) helps people with both cataracts and mild astigmatism see more clearly after cataract surgery.
- Trial name
- NCT07081919
- Testing
- femtosecond laser-assisted arcuate keratotomy (FSAK) combined with standard cataract surgery
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Cataract
Lacrifill for Ocular Surface Optimization in Cataract Surgery
This is a single-site observational study designed to evaluate the efficacy of Lacrifill™ canalicular filler in optimizing ocular surface parameters and biometric precision in prospective cataract surgery patients with dry eye…
- Trial name
- NCT07648095
- Testing
- Lacrifill Canalicular Filler
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- The Eye Institute of West Florida
Cataract
Visual Performance of Clareon Vivity and PureSee IOL
This is study to determine the visual performance of patients with age-related cataracts implanted in both eyes with either of two extended depth of focus intraocular lenses, the Clareon Vivity (Alcon Healthcare) or the PureSee…
- Trial name
- PURVI2 (NCT07165197)
- Testing
- Phacoemulsification with implantation of an extended depth of focus intraocular lens
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- OMIQ Research
Cataract and IOL Surgery, Cataract Surgery Anesthesia
The Impact of Physiologic Cataract Surgery on Patient Comfort and Medication Usage
The study will pertain to investigating the impact of high vs low IOP on the intraoperative experience and comfort for the patient and surgeon.
- Conditions
- Cataract and IOL Surgery, Cataract Surgery Anesthesia, Cataract Surgery Experience, Nuclear Cataract
- Trial name
- NCT07223866
- Testing
- High IOP Setting, Low IOP Setting
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Matthew Rauen
Congenital Cataract, Pediatric Cataract
Five-Year Visual Function and Refractive Outcomes After Congenital Cataract Surgery
This prospective multicenter observational study aims to evaluate the 5-year visual function and refractive outcomes in children undergoing surgery for congenital cataract.
- Trial name
- NCT07070037
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Jin Yang
Ophthalmology, Cataract Surgery Anesthesia
An Extension Test of Whether to Use Oral Anti-anxiety Drugs (Alprazolam) When Patients Choose Second Eye Cataract Surgery After Unblinding, and Analyze Their Anxiety, Satisfaction and Pain Satisfaction
Phacoemulsification is one of the most used surgical methods for cataract surgery today, and the surgeries are under the anesthetic and sedative to make it comfortable and safe for patients.
- Conditions
- Ophthalmology, Cataract Surgery Anesthesia, Oral Anxiolytic, Satisfaction Survey
- Trial name
- NCT06874452
- Testing
- Alprazolam (Xanax)
- Where
- Taiwan
- Volunteers
- 250 people
- Sponsor
- National Taiwan University Hospital