Clinical trials: Cataract Surgery, open to volunteers
Cataract Bilateral, Bilateral Cataracts
Medico-economic Evaluation of Immediately Sequential Bilateral Cataract Surgery Compared With Delayed Sequential Cataract Surgery in France
Cataracts are defined as opacification of all or part of the crystalline lens, resulting in reduced vision. It is a common disease in France, affecting more than one in five people over the age of 65, and almost two in three over…
- Conditions
- Cataract Bilateral, Bilateral Cataracts, Bilateral Cataract
- Trial name
- SIMCAT (NCT06737562)
- Testing
- Immediatly sequential bilateral cataract surgery, Delayed sequential bilateral cataract surgery
- Where
- 4 sites in France
- Volunteers
- 242 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Cataract
A Study on the Application of Smart Bed-Exit Alert Assistive Devices for Detecting Preoperative Bed Exits in Ophthalmic Surgery Patients in the Operating Room
This prospective, randomized interventional study aims to evaluate the effectiveness of a smart bed-exit alert system for patients undergoing cataract surgery during the preoperative waiting period.
- Trial name
- NCT07693829
- Testing
- Smart Bed-Exit Alert System
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Dry Eye, Dry Eye Disease (DED)
Temporary Tear Duct Filling With Hyaluronic Acid Gel and Assessment of Dry Eye Disease (DED) After Bilateral Cataract Surgery
Dry eye disease can occur or worsen after cataract surgery and may cause ocular discomfort and reduced visual quality. Standard treatment commonly includes artificial tear eye drops, which provide temporary lubrication.
- Conditions
- Dry Eye, Dry Eye Disease (DED), Dry Eye Sensation After Cataract Surgery
- Trial name
- TANAMI (NCT07809022)
- Testing
- LACRIFILL® Canalicular Gel administration
- Where
- Austria
- Volunteers
- 25 people
- Sponsor
- Medical University of Vienna
Corneal Astigmatism, Cataract
Effectiveness, Stability and Influence Factors of Femtosecond Laser Assisted Cataract Surgery
What is this study about? This study looks at whether a laser procedure called femtosecond laser-assisted arcuate keratotomy (FSAK) helps people with both cataracts and mild astigmatism see more clearly after cataract surgery.
- Trial name
- NCT07081919
- Testing
- femtosecond laser-assisted arcuate keratotomy (FSAK) combined with standard cataract surgery
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Cataract
Lacrifill for Ocular Surface Optimization in Cataract Surgery
This is a single-site observational study designed to evaluate the efficacy of Lacrifill™ canalicular filler in optimizing ocular surface parameters and biometric precision in prospective cataract surgery patients with dry eye…
- Trial name
- NCT07648095
- Testing
- Lacrifill Canalicular Filler
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- The Eye Institute of West Florida
Cataract
Visual Performance of Clareon Vivity and PureSee IOL
This is study to determine the visual performance of patients with age-related cataracts implanted in both eyes with either of two extended depth of focus intraocular lenses, the Clareon Vivity (Alcon Healthcare) or the PureSee…
- Trial name
- PURVI2 (NCT07165197)
- Testing
- Phacoemulsification with implantation of an extended depth of focus intraocular lens
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- OMIQ Research
Cataract and IOL Surgery, Cataract Surgery Anesthesia
The Impact of Physiologic Cataract Surgery on Patient Comfort and Medication Usage
The study will pertain to investigating the impact of high vs low IOP on the intraoperative experience and comfort for the patient and surgeon.
- Conditions
- Cataract and IOL Surgery, Cataract Surgery Anesthesia, Cataract Surgery Experience, Nuclear Cataract
- Trial name
- NCT07223866
- Testing
- High IOP Setting, Low IOP Setting
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Matthew Rauen
Congenital Cataract, Pediatric Cataract
Five-Year Visual Function and Refractive Outcomes After Congenital Cataract Surgery
This prospective multicenter observational study aims to evaluate the 5-year visual function and refractive outcomes in children undergoing surgery for congenital cataract.
- Trial name
- NCT07070037
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Jin Yang
Ophthalmology, Cataract Surgery Anesthesia
An Extension Test of Whether to Use Oral Anti-anxiety Drugs (Alprazolam) When Patients Choose Second Eye Cataract Surgery After Unblinding, and Analyze Their Anxiety, Satisfaction and Pain Satisfaction
Phacoemulsification is one of the most used surgical methods for cataract surgery today, and the surgeries are under the anesthetic and sedative to make it comfortable and safe for patients.
- Conditions
- Ophthalmology, Cataract Surgery Anesthesia, Oral Anxiolytic, Satisfaction Survey
- Trial name
- NCT06874452
- Testing
- Alprazolam (Xanax)
- Where
- Taiwan
- Volunteers
- 250 people
- Sponsor
- National Taiwan University Hospital
Patient Preference
A Trial Evaluating Patient Preference of Dropless vs Drops Post Cataract Surgery
To evaluate the safety and ocular efficacy of Dextenza in combination with an intracameral antibiotic and NSAID in controlling post-operative ocular pain and inflammation compared to standard of care topical therapy in patients…
- Trial name
- CIMPLIFY (NCT04205916)
- Testing
- Dexamethasone, Standard of care surgery
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ophthalmic Consultants of Long Island
Glaucoma, Cataract
Evaluation of Microinvasive Glaucoma Surgery: MINIject® Versus Hydrus® Microstent in Combination With Cataract Surgery
The study aims to investigate postoperative outcomes after two different MIGS implants (MINIject or Hydrus) in combination with cataract surgery for patients with glaucoma.
- Trial name
- MINHY (NCT06844292)
- Testing
- MINIject with Cataract Surgery, Hydrus Microstent with Cataract Surgery
- Where
- Austria
- Volunteers
- 152 people
- Sponsor
- Medical University of Graz
Cataract
JASPER™ Robotic Surgical System (Formerly Known as the ORYOM™ Robotic Surgical System) in Cataract Surgery
This is a prospective, open-label clinical study designed to evaluate the performance and safety of the JASPER™ Robotic Surgical System during cataract surgery.
- Trial name
- NCT07468409
- Testing
- JASPER™ Robotic Surgical System
- Where
- Philippines
- Volunteers
- 40 people
- Sponsor
- ForSight Robotics Ltd
Cataract, Vitreous Hemorrhage
Surgical Procedure Efficiency Evaluation stuDy
The purpose of this real-world evidence study is to compare surgical procedure times for UNITY® VCS and CONSTELLATION® Vision System.
- Conditions
- Cataract, Vitreous Hemorrhage, Retinal Detachment, Macular Pucker
- Trial name
- NCT07228091
- Testing
- UNITY VCS, CONSTELLATION
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- Alcon Research
Cataract
Visual and Patient Reported Outcomes With Clareon TruPlus
This is a prospective, single-site, two-surgeon, single-arm, observational study evaluating the Clareon TruPlus IOL. Subjects will be assessed up to 3 months post-operatively.
- Trial name
- NCT07648355
- Testing
- Clareon TruPlus
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- OVO LASIK + Lens
Dry Eye, Ocular Surface Disease
Evaluation of Lacrifill
Dry Eye Disease is defined as "a multifactorial disease of the tears and ocular surface that results in symptoms of discomfort, visual disturbance, and tear film instability with potential damage to the ocular surface.
- Conditions
- Dry Eye, Ocular Surface Disease, Cataract Surgery, Eyes Dry Feeling of
- Trial name
- NCT07796178
- Testing
- Lacrifill, Saline
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Eye Research Associates, LLC
Cataract With a Nuclear Sclerosis Grade Between 1 to 3
Zero CDE Technique for Lens Removal During FLACS
The Zero CDE (cumulative dissipated energy) technique facilitates cataract removal with no or minimal phaco energy. This is facilitated by a femtosecond laser, which pre-divides the cataractous lens nucleus into multiple small…
- Trial name
- NCT07404293
- Testing
- Femtosecond laser-assisted cataract surgery using Zero CDE
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- Bochner Eye Institute
Dry Eye
SAS 1: Develop Ocular Disease (OSD) Diagnostic, Algorithms, and Management Protocols for Cataract Surgery
Patient: Tear film issues resulting in poor visual outcomes are a major cause of dissatisfaction after cataract surgery. There is no universal best preoperative algorithm for managing the ocular surface prior to surgery.
- Trial name
- NCT07323264
- Where
- Singapore
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Louis Tong
Cataract Extraction
PRO-232 in Patients Subjected to Cataract Surgery
The main objective of this study is to evaluate the efficacy and safety of the PRO-232 formulation manufactured by Laboratorios Sophia S.A. de C.V.
- Trial name
- PRO-232 (NCT07305987)
- Testing
- Moxifloxacin / Dexamethasone Ophthalmic Solution, Moxifloxacin Hydrochloride, Ophthalmic, Dexamethasone phosphate
- Where
- 2 sites in Mexico
- Volunteers
- 134 people
- Sponsor
- Laboratorios Sophia S.A de C.V.
Endophthalmitis
Safety and Efficacy of Intracameral Zimoxin for Prevention of Endophthalmitis After Cataract Surgery
Intracameral injection of 0.1% moxifloxacin solution after cataract surgery to prevent endophthalmitis
- Trial name
- NCT03244072
- Testing
- Moxifloxacin
- Where
- United States
- Volunteers
- 60,000 people, healthy volunteers welcome
- Sponsor
- Jason Ahee, M.D.
Dry Eye
Impact of Cataract Surgery on the Incidence and Progression of Dry Eye Disease
Relation between dry eye and cataract
- Trial name
- NCT06759168
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Assiut University