Clinical trials: Cataract Surgery
Cataract
Visual Acuity After the Combined Binocular Implantation of +2.0 Diopters and +3.0 Diopters Oculentis Multifocal Intraocular Lenses.
The objective of this study is to assess the visual outcome after the combined binocular implantation of +2.0 D and +3.0 D refractive multifocal intraocular lenses.
- Trial name
- NCT02633228
- Testing
- Binocular cataract surgery with phacoemulsification and implantation of multifocal intraocular lenses
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- PD Dr. med. Eckart Bertelmann
Cataract
An Interocular Comparative Study of Unilateral Cataract
The purpose of this cross-sectional study is to compare bilateral anterior segment parameters, macular thickness, and BCVA at 3 months after uncomplicated unilateral pediatric cataract extraction with primary IOL implantation to…
- Trial name
- NCT02765230
- Where
- China
- Volunteers
- 53 people
- Sponsor
- Sun Yat-sen University
Cataract Surgery
The Effect of Hand Holding and Stress Ball Intervention on Pain and Anxiety
Cataract surgery is currently primarily performed with topical anesthesia. Although topical anesthesia provides many benefits for patients, they may experience pain, anxiety and discomfort during surgery.
- Trial name
- NCT07108192
- Testing
- Hand Holding, Stress Ball, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Sakarya University
Macular Edema, Epiretinal Membrane
Epiretinal Membrane and Pseudophakic Cystoid Macular Edema
Prospective, observational cohort study evaluating the association between pre-surgical existence of an epiretinal membrane (ERM) and the development of pseudophakic cystoid macular edema (PCME) using spectral domain optical…
- Trial name
- NCT02693353
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Loma Linda University
Inflammation and Pain Following Ocular Surgery
RTA 408 Ophthalmic Suspension for the Treatment of Ocular Inflammation and Pain Following Ocular Surgery
This study assesses the efficacy and safety of two concentrations of RTA 408 Ophthalmic Suspension in the treatment of patients who have inflammation and pain following ocular surgery.
- Trial name
- NCT02065375
- Testing
- Omaveloxolone Ophthalmic Suspension 1.0%, Omaveloxolone Opthalmic Suspension 0.5%
- Where
- 6 sites in United States
- Volunteers
- 109 people
- Sponsor
- Biogen
Pediatric Cataract, Congenital Cataract
New Technique in Congenital/Pediatric Cataract Surgery
In pediatric/congenital cataract surgery; multiple surgical interventions are performed, which needs multiple general anesthesias. Here, we describe a new technique, to end the operation in one session.
- Trial name
- NCT05278936
- Testing
- The cataract surgery and the anterior vitrectomy
- Where
- Iraq
- Volunteers
- 52 people
- Sponsor
- Omer Othman Abdullah
Cataract Surgery
Pilot Study: Feasibility and Usability of a Head-Mounted Spatial Computing Device for Intraoperative Visualization During Intraocular Surgery
To evaluate the feasibility and usability of Apple Vision Pro as an adjunct visualization and information display tool during ophthalmic surgery.
- Trial name
- NCT07825337
- Testing
- Apple Vision Pro Visualization System
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Eric Rosenberg
Cataract
Lidocaine Usage for Pupil Dilatation (Mydriasis)
The purpose of this study is to determine if the mydriatic effect of intracameral lidocaine 1% is as effective as topical cyclopentolate 1% and phenylephrine 10% for achieving effective mydriasis during phacoemulsification…
- Trial name
- NCT01170130
- Testing
- Lidocaine 1% (sterile)
- Volunteers
- 100 people
- Sponsor
- Carmel Medical Center
Cataracts
Selection of Aspheric Diffractive Multifocal Intraocular Lens (IOLS) Based on Corneal Wavefront
Given the availability of aspheric diffractive IOLs with varying negative spherical aberration it may be feasible, by selecting the best fit IOL, to minimize aberrations and thereby maximize visual performance.
- Trial name
- NCT00999492
- Testing
- Tecnis® Multifocal (TMF)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Mark Packer, MD, FACS
Epiretinal Membranes, Macular Holes
Blue-Blocking IOLs in Combined Surgery
Although commonly used in cataract surgery, the use of the blue light-filter IOLs in vitrectomy combined with cataract surgery has not been reported yet.
- Conditions
- Epiretinal Membranes, Macular Holes, Cataract
- Trial name
- NCT00537992
- Testing
- combined surgery
- Volunteers
- 60 people
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Cataract (Post-operative Cataract Surgery Follow-up)
Vision Center Determinants of Cataract Follow-Up in Rural India
Cataract remains the leading cause of avoidable blindness in India despite substantial expansion of surgical services over the past two decades.
- Trial name
- NCT07513402
- Testing
- Follow-Up Strengthening Intervention Framework
- Volunteers
- 150 people
- Sponsor
- Seva Canada Society
Aphakia, Cataract
Registry Study on Intraocular Lenses Manufactured by Teleon Surgical B.V.
This is a retrospective, observational (Registry) study aiming to collect safety and performance data on the use of intraocular lenses (IOLs) manufactured by Teleon Surgical B.V. according to routine practice.
- Conditions
- Aphakia, Cataract, Clear Lens Exchange, Refractive Lens Exchange
- Trial name
- NCT05290870
- Testing
- Posterior-chamber intraocular lens
- Where
- Netherlands
- Volunteers
- 2,183 people
- Sponsor
- Teleon Surgical B.V.
Cataract Surgery, Eye Dryness
Low-level Light Therapy Versus Intense Pulsed Light to Prevent Iatrogenic Dry Eye Disease After Cataract Surgery
Dry eye disease (DED) is a frequent ocular surface disease (OSD) of multifactorial origin, characterised by disruption of tear film homeostasis and associated with ocular discomfort and/or visual disturbance.
- Trial name
- EDACS (NCT07055022)
- Testing
- LLLT, IPL
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Clinique Trenel
Cataracts
Comparison of the Effectiveness of Povidone-iodine in Reducing Conjunctival Bacterial Load Prior to Cataract Surgery in Patients Treated With a Lidocaine Gel Dilating Formulation Versus Eye Drops: A Randomized Controlled Trial
The eye contains a lens that focuses light. A clouding of the lens is known as a cataract. Cataracts decrease vision. The treatment for cataracts is cataract surgery.
- Trial name
- NCT01898728
- Testing
- topical povidone-iodine after premedication with topical liquid eye drops, topical povidone-iodine after premedication with topical gel
- Where
- Canada
- Volunteers
- 101 people
- Sponsor
- McMaster University
Cataract
Loteprednol vs Prednisolone for the Treatment of Intraocular Inflammation Following Cataract Surgery in Children.
The objective of this study is to compare the efficacy and safety for the treatment of postoperative inflammation following ocular surgery for childhood cataract.
- Trial name
- NCT01475643
- Testing
- Loteprednol etabonate, Prednisolones acetate
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Bausch & Lomb Incorporated
Aphakia, Cataract
Clinical Study to Evaluate the Safety and Effectiveness of the RxSight Light Adjustable Lens (LAL) in Subjects With Prior Corneal Refractive Surgery
The primary objective of this study is to evaluate, for the visual correction of aphakia, the safety and effectiveness of the RxSight Light Adjustable Lens (LAL) and Light Delivery Device (LDD) to reduce postoperative refractive…
- Trial name
- NCT03660865
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD), Control IOL
- Where
- 6 sites in United States
- Volunteers
- 105 people
- Sponsor
- RxSight, Inc.
Cataract, Astigmatism
Toric Intraocular Lens Following Cataract Surgery
The objective of this clinical trial is to evaluate the safety and effectiveness of the Bausch + Lomb Toric Accommodating Posterior Chamber Silicone Intraocular Lens used to provide near, intermediate, and distance vision and a…
- Trial name
- NCT01140477
- Testing
- Toric Accommodating Lens, Accommodating Lens
- Where
- United States
- Volunteers
- 229 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract, Age-related Cataract
Association Between Light Spectrum and Survival After Cataract Surgery
This study was a retrospective observational cohort analysis of subjects aged 65 years and older, who underwent bilateral cataract surgery within a single (15 hospital) healthcare system, to determine the association between type…
- Conditions
- Cataract, Age-related Cataract, Circadian Rhythm Disorders, Glaucoma
- Trial name
- NCT04187157
- Testing
- Blue-light filtering intraocular lens, Conventional intraocular lens
- Where
- United States
- Volunteers
- 10,192 people
- Sponsor
- University of Pittsburgh
Presbyopia, Cataract
The Effect of Cataract Extraction on the Contractility of Ciliary Muscle
The purpose of this study is to investigate the changes in the pilocarpine-induced ciliary body movement before and after cataract extraction in order to determine the effect of lens sclerosis on the ciliary muscle contractility.
- Trial name
- NCT00624039
- Testing
- UBM with pilocarpine in presbyopia
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Samsung Medical Center
Cataract, Anxiety
Delta-Wave Hypnoanalgesia for Reducing Perioperative Anxiety in Cataract Surgery
This prospective, randomized, single-blind trial evaluated the effect of delta-wave binaural beat audio hypnoanalgesia, a non-pharmacological hypnosis technique, on reducing perioperative anxiety and improving hemodynamic…
- Trial name
- NCT07099209
- Testing
- Delta-Wave Hypnoanalgesia
- Where
- Tunisia
- Volunteers
- 198 people
- Sponsor
- Military Hospital of Tunis