Clinical trials: Cataract and IOL Surgery
Age-related Cataract
EDOF vs Enhanced vs Monofocal IOLs After Bilateral Cataract Surgery
Consecutive comparative case series evaluating visual outcomes and patientreported satisfaction after bilateral cataract surgery with implantation of the same IOL type (standard monofocal, enhanced monofocal, or novel EDOF IOL).
- Trial name
- NCT07548294
- Where
- Turkey (Türkiye)
- Volunteers
- 197 people
- Sponsor
- Sakarya Yenikent State Hospital
Cataract Congenital
Multifocal vs Monofocal IOL in Congenital Cataract Surgery
The aim of this study is to evaluate long-term outcome after congenital cataract surgery comparing results achieved with multifocal and monofocal IOLs.
- Trial name
- NCT04872829
- Testing
- cataract surgery
- Volunteers
- 43 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Age Related Cataracts, Pseudoexfoliation Syndrome
Outcome of Two Surgical Methods for IOLImplantation in Eyes With Pseudoexfoliation Syndrome
The aim of this study is to compare the surgical outcomes of the two IOL implantation methods for eyes with cataract and PEX in a single-center and with highly experienced surgeons.
- Trial name
- NCT06053554
- Testing
- Phakoemulsification, Ziemer Z8 Femtolaser, Kowa Avansee Preset
- Where
- Austria
- Volunteers
- 120 people
- Sponsor
- Medical University of Vienna
Cataract and IOL Surgery, Cataract Surgery Anesthesia
The Impact of Physiologic Cataract Surgery on Patient Comfort and Medication Usage
The study will pertain to investigating the impact of high vs low IOP on the intraoperative experience and comfort for the patient and surgeon.
- Conditions
- Cataract and IOL Surgery, Cataract Surgery Anesthesia, Cataract Surgery Experience, Nuclear Cataract
- Trial name
- NCT07223866
- Testing
- High IOP Setting, Low IOP Setting
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Matthew Rauen
Cataract, Presbyopia Correction
Night Driving After Trifocal Versus Monofocal IOL Implantation
This prospective observational cohort study will compare night-driving visual difficulty and visual disturbances after bilateral implantation of an Alcon trifocal intraocular lens or an Alcon monofocal intraocular lens in adults…
- Trial name
- TriIOL (NCT07755189)
- Testing
- AcrySof IQ PanOptix TFNT00 Trifocal Intraocular Lens, Alcon Monofocal Intraocular Lens
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Jin Yang
Cataract, Refractive Errors
Comparison of Intraocular Lens Power Calculation Methods After Corneal Laser Refractive Surgery in Axial and Refractive Ammertropia
The study aims at determining the best biometry calculation formula to be used in IOL calculation of cataract patients how previously underwent laser refractive correction surgery
- Trial name
- NCT01979172
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- The National Eye Hospital, Cairo, Egypt
Cataract
Trial Following Subjects Bilaterally Implanted With Mini Well Ready For 2 Years After the Second Eye Implant
The study objective is to evaluate the visual performance of MINI WELL Ready at 24 months following the second eye implant. The objectives of safety are to evaluate the rate of Secondary Surgical Interventions related to the…
- Trial name
- NCT04801992
- Testing
- MINI WELL Ready (SIFI SpA, Italy)
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- SIFI SpA
Astigmatism, Cataract
Astigmatism Management With Iris-registration Guided Corneal Relaxing Incisions or Toric IOLs During Cataract Surgery
Most of the patients presenting for cataract surgery also have pre-existing corneal astigmatism which if left uncorrected can adversely affect visual and refractive outcomes after cataract surgery.
- Trial name
- NCT05561296
- Testing
- Femtosecond laser assisted cataract surgery with astigmatism management
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Kenneth J Rosenthal
Cataract, Surgery
Comparison of Visual Outcomes After Implantation of the Synthesis Plus and Synthesis Plus Toric
Prospective controlled monocentric study to determine the non-inferiority of the distance-corrected intermediate visual acuity at 66 cm of the SYNTHESIS PLUS TORIC with respect to the SYNTHESIS PLUS IOL.
- Conditions
- Cataract, Surgery, IOL
- Trial name
- DETPLUST (NCT05561478)
- Testing
- Implantation of Synthesis Plus IOL (control device), Implantation of Synthesis Plus Toric IOL (investigational device)
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Cutting Edge SAS
Cataract
Postmarket Study of an Intraocular Lens Power Selection System
The purpose of the study was to evaluate the visual acuity outcomes when using the Optiwave Refractive Analysis (ORA) with VerifEye+ and Barrett Toric Calculator for calculating intraocular lens (IOL) power and axis in subjects…
- Trial name
- NCT03579433
- Testing
- ORA with VerifEye+, Alcon Barrett Toric Calculator, Acrysof® IQ Toric IOL
- Where
- 9 sites in United States
- Volunteers
- 124 people
- Sponsor
- Alcon Research
Cataract and IOL Surgery, Keratoplasty
Postoperative Outcomes of a Toric AddOn Intraocular Lens After Keratoplasty and Cataract Surgery
The aim of this clinical study is to evaluate a toric add-on intraocular lens (IOL) for the correction of high astigmatism in patients who have undergone keratoplasty and cataract surgery.
- Conditions
- Cataract and IOL Surgery, Keratoplasty, Toric Intraocular Lens Stability
- Trial name
- AddOn (NCT07452042)
- Testing
- AddOn toric IOL implantation
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Vienna
Contrast Sensitivity
Contrast Sensitivity Assessment in Pediatric Cataract Surgery With IOL Implantation
The study evaluates contrast sensitivity in older children following surgery for lamellar and posterior subcapsular cataracts. Often, pediatric surgeons tend to delay surgery in these children who present beyond the amblyogenic…
- Trial name
- NCT01901744
- Testing
- Cataract Surgery
- Where
- India
- Volunteers
- 25 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Cataract
The SITE Study - Dexamethasone Ophthalmic Insert In OR on Day of Surgery Versus In-office Post-Op Day 1
To assess the safety and effectiveness of treatment with an intracanalicular dexamethasone (0.4mg) insert in the operating room following cataract surgery/intraocular lens implant (IOL) compared to insertion 1-day post-op.
- Trial name
- NCT05143281
- Testing
- Dexamethasone 0.4 MG [Dextenza]
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Grene Vision Group
Cataract, Anterior Chamber Inflammation
Iontophoretic Delivery of EGP-437 in Patients Who Have Undergone Cataract Surgery
Phase 2b trial evaluating the safety and efficacy of EGP-437, versus placebo using the EyeGate® II Drug Delivery System (EGDS) in patients having undergone cataract surgery with implantation of a monofocal posterior chamber…
- Conditions
- Cataract, Anterior Chamber Inflammation, Pain, Postoperative
- Trial name
- NCT03180255
- Testing
- Dexamethasone phosphate
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Eyegate Pharmaceuticals, Inc.
Aphakia, Astigmatism
Evaluation of Long-term Safety and Performance of PanOptix Trifocal Intraocular Lens (IOL)
The purpose of this Post-Market Clinical Follow-up (PMCF) study is to describe the long-term safety and performance of the AcrySof IQ PanOptix IOL toric and non-toric models in subjects bilaterally implanted with these IOLs for 3…
- Conditions
- Aphakia, Astigmatism, Presbyopia
- Trial name
- NCT06166901
- Testing
- AcrySof IQ PanOptix IOL Toric, AcrySof IQ PanOptix IOL Non-Toric
- Where
- 7 sites in Spain
- Volunteers
- 211 people
- Sponsor
- Alcon Research
Cataract
AI-Driven IOL Prediction Using SS-OCT Biometry
This prospective, multicenter, non-interventional observational study aims to evaluate the agreement between a novel swept-source optical coherence tomography (SS-OCT) biometer and the IOLMaster 700 for ocular biometric…
- Trial name
- NCT07733154
- Testing
- IOLMaster 700, Novel SS-OCT Biometer
- Where
- 3 sites in Australia, China and 1 more
- Volunteers
- 2,500 people
- Sponsor
- The Hong Kong Polytechnic University
Pseudophakia, Accomodation
Monofocal Extended Range of Vision (MERoV) Study
The investigators are proposing this research project to: 1. Screen a set of patients after normal cataract surgery with a single focus lens aimed at good distance vision at 3 months after surgery to identify patients who are…
- Conditions
- Pseudophakia, Accomodation, Aberration, Corneal Wavefront
- Trial name
- MERoV (NCT04011696)
- Where
- United Kingdom
- Volunteers
- 412 people
- Sponsor
- Brighton and Sussex University Hospitals NHS Trust
Cataract
Postoperative Outcome Verification of Discrepant Toric IOL Calculator Recommendations After Cataract Surgery
The goal of this observational study is to learn which toric lens calculator best predicts the astigmatism remaining after cataract surgery in adults who received a TECNIS DIU toric intraocular lens (IOL) at Klinik Hietzing…
- Trial name
- NCT07880249
- Testing
- Standardized Postoperative Outcome Visit, Toric IOL Calculator Pathways (Exposure)
- Volunteers
- 128 people
- Sponsor
- Vienna Hospital Association
Iol, Astigmatism
Clinical Evaluation of Efficacy and Stability of AT TORBI 709M 4-haptic Toric IOL in Cataract Surgery
The purpose of this study is to evaluate the efficacy and stability of AT TORBI 709M 4-haptic toric IOL in cataract surgery.
- Trial name
- NCT02618018
- Testing
- AT TORBI 709M
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Seoul National University Hospital
Cataract
Satisfaction & Spectacle Independence With ReSTOR 2.5 & ReSTOR 3.0 IOLs
Patients implanted with the ReSTOR 2.5 multifocal IOL in the dominant eye and the ReSTOR 3.0 in the non-dominant eye have overall satisfaction and spectacle independence at least comparable to that with bilateral implantation of…
- Trial name
- NCT03073681
- Testing
- Survey
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- MDbackline, LLC