Clinical trials: Cataract and Intraocular Lens Surgery
Cataract, Corneal Astigmatism
ClarVista HARMONI Toric Trial With Intraoperative Exchange
The purpose of this study was to demonstrate the safety and effectiveness of the HARMONI® Modular Intraocular Lens System with a toric optic in subjects with pre-existing corneal astigmatism in need of cataract surgery.
- Conditions
- Cataract, Corneal Astigmatism, Aphakia
- Trial name
- NCT03054649
- Testing
- HARMONI® Modular Intraocular Lens System, Intraoperative optic exchange
- Where
- 2 sites in Mexico, Philippines
- Volunteers
- 44 people
- Sponsor
- ClarVista Medical
Primary Open Angle Glaucoma (POAG), Cataract
Study of an Implantable Device for Lowering Intraocular Pressure in Glaucoma Patients Undergoing Cataract Surgery
The purpose of this study is to evaluate the safety and efficacy of the CyPass Implant for lowering intraocular pressure (IOP) in patients with glaucoma who undergo cataract surgery.
- Trial name
- COMPASS (NCT01085357)
- Testing
- Cataract Surgery, CyPass Micro-Stent
- Volunteers
- 897 people
- Sponsor
- Transcend Medical, Inc.
Posterior Capsule Opacification
Posterior Capsule Opacification Following Cataract Surgery With Implantation of the MICS IOL L313
This study collects intra- and postoperative data from the patients´charts retrospectively and evaluates retro- and prospectively the rate of posterior capsule opacification (PCO) following implantation of the intraocular lens L…
- Trial name
- NCT03184428
- Testing
- Postoperative observation and survey
- Where
- Germany
- Volunteers
- 3,785 people
- Sponsor
- Dietrich-Bonhoeffer-Klinikum
Aphakia, Cataract
Clinical Study to Evaluate the Safety and Effectiveness of the RxSight Light Adjustable Lens (LAL) in Subjects With Prior Corneal Refractive Surgery
The primary objective of this study is to evaluate, for the visual correction of aphakia, the safety and effectiveness of the RxSight Light Adjustable Lens (LAL) and Light Delivery Device (LDD) to reduce postoperative refractive…
- Trial name
- NCT03660865
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD), Control IOL
- Where
- 6 sites in United States
- Volunteers
- 105 people
- Sponsor
- RxSight, Inc.
Cataract Extraction, Phacoemulsification
A Study Comparing Two Monofocal, Aspheric, Hydrophobic Acrylic Intraocular Lenses: the Alcon CLAREON® and the Abbott Medical Optics PCB00
This is a bilateral randomised controlled study to compare visual performance, refractive outcome, forward light scatter, patient satisfaction and objective measurement of glistenings following insertion of two monofocal…
- Conditions
- Cataract Extraction, Phacoemulsification, Glistenings, Intraocular Lens Implant
- Trial name
- NCT03364972
- Testing
- Cataract surgery
- Where
- United Kingdom
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Cataract
Evaluating Patient Satisfaction After Cataract Surgery With Multifocal Intraocular Lens
Multifocal lens allow most patients to be spectacle-free after cataract surgery. Most studies published up-to-date have focused on visual acuity, but not on patient-reported outcomes.
- Trial name
- NCT03787576
- Testing
- Cataract surgery
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Clínica Rementería
Cataract
Medications Effect on Lenstar Measurements
Prior to cataract surgery the lens must be calculated to appropriately fit a patient for the intraocular lens implant. Lenstar is an optical biometer that calculates the axial length, keratometry, lens thickness, pupillometry…
- Trial name
- NCT02780063
- Testing
- Lenstar Biometer
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NYU Langone Health
Cataract Surgery, Glaucoma Surgery
PREFERENTIAL Study
To determine patient preference for the dexamethasone insert or topical prednisolone therapy through at Day 45 as measured by - Modified COMTOL survey.
- Trial name
- NCT04563559
- Testing
- Dextenza 0.4Mg Ophthalmic Insert, Prednisolone Acetate 1% Ophthalmic Suspension [PRED FORTE]
- Sponsor
- Duke University
Endothelial Cell Loss, Corneal, Cataract and Intraocular Lens (IOL) Surgery
Effect of Vitamin C Supplementation in Corneal Endothelial Damage in Phacoemulsification of Patients with Hard Cataracts
The goal of this clinical trial is to analyze the protective effects of oral ascorbic acid on the corneal endothelial layer undergoing oxidative stress due to phacoemulsification in patients with hard cataracts.
- Trial name
- NCT06781970
- Testing
- Oral Vitamin C
- Where
- 2 sites in Indonesia
- Volunteers
- 120 people
- Sponsor
- Universitas Indonesia
Postoperative Ocular Inflammation, Postoperative Ocular Pain
A Phase 3 Study Evaluating the Safety and Efficacy of TRIESENCE® (Injectable Suspension) for the Treatment of Ocular Inflammation and Pain After Ophthalmic Surgery
This study is designed to evaluate the safety and efficacy of TRIESENCE® (triamcinolone acetonide injectable suspension) in patients undergoing ophthalmic procedures.
- Trial name
- NCT07832552
- Testing
- TRIESENCE (triamcinolone acetonide injectable suspension)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Harrow Inc
Cataract, Glaucoma
Comparison of Phaco-Trabeculectomy and MSICS-Trab in Cataract and Glaucoma Patients
The goal of this interventional study is to compare the outcomes of two surgical techniques, Phaco-Trabeculectomy and Manual Small Incision Cataract Surgery (MSICS) with Trabeculectomy, in patients with coexisting cataract and…
- Trial name
- NCT06739343
- Testing
- PHACO-Trabeculectomy, MSICS-Trabeculectomy
- Where
- Nigeria
- Volunteers
- 122 people
- Sponsor
- Emeka John Dingwoke
Cataract, Glaucoma
High Frequency Deep Sclerotomy (HFDS) ab Interno a Combination Surgical Intervention Using Cataract Surgery to Lower IOP
Objective: To compare intraocular pressure lowering effect of combined sclerotomy ab interno with phacoemulsification and phacoemulsification alone, in primary or secondary open angle glaucoma patients.
- Conditions
- Cataract, Glaucoma, POAG
- Trial name
- HFDS_abinterno (NCT02312362)
- Testing
- Combined sclerotomy ab interno and phaco, Phacoemulsification with IOL implantation
- Where
- 5 sites in Egypt, Germany and 2 more
- Volunteers
- 108 people
- Sponsor
- Oertli Instrumente AG
Aphakia, Cataract
Registry Study on Intraocular Lenses Manufactured by Teleon Surgical B.V.
This is a retrospective, observational (Registry) study aiming to collect safety and performance data on the use of intraocular lenses (IOLs) manufactured by Teleon Surgical B.V. according to routine practice.
- Conditions
- Aphakia, Cataract, Clear Lens Exchange, Refractive Lens Exchange
- Trial name
- NCT05290870
- Testing
- Posterior-chamber intraocular lens
- Where
- Netherlands
- Volunteers
- 2,183 people
- Sponsor
- Teleon Surgical B.V.