Clinical trials: Cataracts
Cataracts
Contralateral ReSTOR / Monofocal or Phakic Eye
Bilateral evaluation of unilateral implantation of ReSTOR and contralateral monofocal or phakic eye.
- Trial name
- NCT00731640
- Testing
- ReSTOR
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Alcon Research
Dry Eye Disease, Cataract
Systane Hydration in Subjects Undergoing Cataract Surgery
The primary objective of this study is to demonstrate reduced corneal staining with use of Systane Hydration among subjects with dry eye disease (DED) undergoing routine cataract removal and monofocal intraocular lens (IOL)…
- Trial name
- NCT05056233
- Testing
- Systane Hydration lubricant eye drops
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- Alcon Research
Ocular Inflammation
Comparison Study of ISV-303 to Durasite Vehicle in Cataract Surgery Subjects
The purpose of this study is to evaluate the ocular safety, tolerability and efficacy of topical administration of ISV-303 compared with Durasite Vehicle.
- Trial name
- NCT01808547
- Testing
- ISV-303, DuraSite Vehicle
- Volunteers
- 268 people
- Sponsor
- Sun Pharmaceutical Industries Limited
Cataracts
AcrySof® IQ ReSTOR® +2.5 D Multifocal Intraocular Lens (IOL) Model SN6AD2 [SV25T0] in Japan
The purpose of this study is to evaluate safety and effectiveness of AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0] in Japanese cataract patients.
- Trial name
- NCT01605877
- Testing
- AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0]
- Where
- 2 sites in Japan
- Volunteers
- 70 people
- Sponsor
- Alcon Research
Cataract
Assessment of Low Energy Lens Fragmentation Cataract Extraction in Patients Undergoing Cataract Surgery
The purpose of this research study is to evaluate the clinical outcomes of the use of low-energy segment removal with a micro-interventional irrigation/aspiration port (MICOR-304) to evacuate the lens prior to intraocular lens…
- Trial name
- NCT04747834
- Testing
- MICOR-304
- Where
- 3 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Cataract
Clinical Evaluation of a New Aspheric Intraocular Lens.
This study evaluates the visual performance and occurrence of posterior capsular opacification after implantation of a new aspherical intraocular lens compared with a control spherical lens of otherwise identical design.
- Trial name
- NCT00786565
- Testing
- Advanced Akreos Adapt in one operated eye., Akreos Adapt in fellow operated eye.
- Volunteers
- 75 people
- Sponsor
- Bausch & Lomb Incorporated
Cataracts, Meibomian Gland Dysfunction (MGD)
A Post-Market Evaluation of LipiFlow Treatment in Cataract Surgery Practice
This is a post-market, prospective, randomized, multi-center, bilateral, open-label, cross-over, comparative clinical study. Study group will undergo preoperative LipiFlow treatment and Control group will not receive preoperative…
- Trial name
- NCT03708367
- Testing
- LipiFlow Thermal Pulsation System
- Where
- 5 sites in United States
- Volunteers
- 117 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Aphakia, Presbyopia
Post Approval Study of the AcrySof® IQ ReSTOR® Toric IOLs
This is a prospective, multicenter, post-approval active surveillance study. The purpose of this study is to report the rate of post-surgical intraocular inflammation (based upon a specified case definition) reported within a…
- Conditions
- Aphakia, Presbyopia, Astigmatism
- Trial name
- NCT03733730
- Testing
- ACRYSOF IQ RESTOR +3.0 Multifocal Toric IOL, ACRYSOF IQ RESTOR +2.5 D Multifocal Toric IOL, ACRYSOF IQ RESTOR +2.5 D Multifocal IOL
- Where
- 38 sites in United States, Puerto Rico
- Volunteers
- 2,449 people
- Sponsor
- Alcon Research
Cataract
Evaluation of the BunnyLens TR Intraocular Lens
With age, a human crystalline lens opacifies (cataract) disabling the eye in generating a clear, well contrasted image. The only therapeutic solution to this problem is surgical replacement of the crystalline lens with an…
- Trial name
- NCT01659801
- Testing
- BunnyLens TR
- Volunteers
- 25 people
- Sponsor
- Hanita Lenses
Presbyopia, Cataract
Feasibility Study of Laser Treatment of the Crystalline Lens to Correct Presbyopia
The study will evaluate whether the LensAR laser system can be used in the lens of the eye to increase the ability to read and/or see near objects
- Trial name
- NCT01062412
- Testing
- LensAR Laser System
- Where
- Philippines
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- LensAR Incorporated
Cataract, Lens Opacities
Visual Performance, Patient Satisfaction and PCO Rate After Implantation of a Trifocal Hydrophobic IOL
Prospective, controlled, single-surgeon, single-center post-market clinical follow up study to investigate the clinical outcomes of a hydrophobic trifocal IOL (PhysIOL POD F GF)
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- PHY1703 (NCT03306342)
- Testing
- IOL implantation experimental
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract
Comparison of Visual Outcomes After Implantation of the POD FT and the POD F
There is no difference of the photic phenomena in the two groups. The study will be a prospective non-randomised controlled study. The target is then to determine the equivalence in the glare.
- Trial name
- PoyPODF/FT (NCT04943809)
- Testing
- POD 26P AY FT, POD 26P AY F
- Where
- Spain
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract
Nepafenac 0.3% Two Study
The purpose of this study was to assess the safety and efficacy of Nepafenac Ophthalmic Suspension, 0.3% for the prevention and treatment of inflammation (swelling and redness) and pain in the eye after cataract extraction.
- Trial name
- NCT01318499
- Testing
- Nepafenac Ophthalmic Suspension, 0.3%, Nepafenac Ophthalmic Suspension, 0.1%, Nepafenac Vehicle 0.3%
- Where
- United States
- Volunteers
- 1,342 people
- Sponsor
- Alcon Research
Intraocular Lens Replacement
Safety and Efficacy of OMS302 in Subjects Undergoing Intraocular Lens Replacement With Phacoemulsification
The purpose of this study is to determine the safety and efficacy of OMS302 (the study drug) for maintaining intraoperative mydriasis in individuals undergoing Intraocular Lens Replacement (ILR) surgery.
- Trial name
- OMS302-ILR-003 (NCT01454063)
- Testing
- OMS302
- Where
- 16 sites in United States
- Volunteers
- 405 people
- Sponsor
- Omeros Corporation
Inflammatory Reaction Due to Ocular Lens Prosthesis
Efficacy and Safety Study of IBI-10090 in Patients Undergoing Cataract Surgery
This study will test the efficacy and safety of IBI-10090 for the reduction of ocular inflammation after cataract surgery.
- Trial name
- NCT01048593
- Testing
- IBI-10090
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- ICON Bioscience Inc
Diabetic Retinopathy
Macular Edema Incidence/Severity Reduction With Nevanac
The purpose of this study is to evaluate NEVANAC in patients with diabetic retinopathy who developed macular edema (ME) within 90 days following cataract surgery.
- Trial name
- NCT00939276
- Testing
- Nepafenac ophthalmic suspension, 0.1% (NEVANAC®), Nepafenac ophthalmic suspension vehicle
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- Alcon Research
Cataract, Pseudophakia
Retrospective, Non-interventional Clinical Investigation of the Safety and Performance of 640AD Monofocal Intraocular Lens
Medicontur hydrophilic posterior chamber monofocal intraocular lens (IOL) is indicated to improve vision at far distance in adults with cataract and/or ametropia (hyperopia, myopia), secondarily to removal of the crystalline…
- Trial name
- NCT06578910
- Testing
- Standard of care, Patient satisfaction questionnare
- Where
- Hungary
- Volunteers
- 80 people
- Sponsor
- Medicontur Medical Engineering Ltd
Cataract
A Study to Evaluate the enVista® Aspire (EA) Intraocular Lens in Subjects Undergoing Cataract Extraction
A Study to Evaluate the enVista® Aspire (EA) intraocular lens in Subjects Undergoing Cataract Extraction
- Trial name
- NCT06333028
- Testing
- enVista Aspire EA IOLs
- Where
- 7 sites in United States
- Volunteers
- 82 people
- Sponsor
- Bausch & Lomb Incorporated
Cancer, Cataract
Evaluation of New or Worsening Lens Opacifications in Men With Non-metastatic Prostate Cancer Receiving Denosumab for Bone Loss
This is a phase 3, randomized, double-blind, placebo-controlled study to evaluate new or worsening lens opacifications in men with non-metastatic prostate cancer receiving denosumab for bone loss due to androgen deprivation…
- Conditions
- Cancer, Cataract, Low Bone Mineral Density, Osteopenia
- Trial name
- NCT00925600
- Testing
- Denosumab
- Where
- 172 sites in United States, Australia and 16 more
- Volunteers
- 769 people
- Sponsor
- Amgen
Cataract, Refractive Error
A Comparative Study of TECNIS Symfony Plus IOL and a Trifocal IOL
This is a multicenter, prospective, randomized, subject- and evaluator-masked, bilateral-implant study conducted at up to 15 sites worldwide.
- Trial name
- NCT04156737
- Testing
- TECNIS Symfony plus IOL Model ZHR00V, Trifocal Intraocular lens
- Where
- 5 sites in New Zealand, Philippines and 1 more
- Volunteers
- 205 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.