Clinical trials: Cataracts
Senile Cataract
621 Real World Study
This study is evaluating the clinical safety and effectiveness of 621, after cataract surgery.
- Trial name
- NCT05646004
- Testing
- Cataract surgery
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Carl Zeiss Meditec AG
Cataracts
A Multicenter, Observational, Single Arm Study of the TECNIS Presbyopia-correcting Intraocular Lens
Ambispective post-market data collection on visual symptoms, patient satisfaction and surgeon experience with the TECNIS PC IOL.
- Trial name
- NCT06250322
- Testing
- Intervention
- Where
- 20 sites in Australia, Austria and 6 more
- Volunteers
- 307 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Cataract
A Study to Evaluate Real World Outcomes of the enVista® Aspire (EA) and Aspire Toric (ETA) Intraocular Lens in Subjects Undergoing Cataract Extraction
A study to evaluate the real-world clinical performance of the enVista Aspire and Aspire Toric intraocular lens (IOL) models EA and ETA and to assess surgeon and subject satisfaction
- Trial name
- NCT06594185
- Testing
- enVista Aspire EA or Aspire Toric ETA IOLs
- Where
- 62 sites in United States
- Volunteers
- 335 people
- Sponsor
- Bausch & Lomb Incorporated
Aphakia, Astigmatism
Clareon TruPlus Study
The purpose of this research study is to generate safety and performance data for Clareon TruPlus Monofocal Intraocular Lenses (IOLs).
- Trial name
- NCT07502456
- Testing
- Clareon TruPlus Monofocal Non-Toric IOL, Clareon TruPlus Monofocal Toric IOL, Phacoemulsification
- Where
- 5 sites in United States
- Volunteers
- 122 people
- Sponsor
- Alcon Research
Aphakia, Presbyopia
Clareon PanOptix Pro vs. Clareon PanOptix - Study B
The purpose of this study is to evaluate the safety and effectiveness of Clareon™ PanOptix™ Pro Trifocal Intraocular Lens (IOL) compared to Clareon™ PanOptix™ Trifocal IOL.
- Trial name
- NCT06401551
- Testing
- CPO Pro IOL, CPO IOL, Cataract Surgery
- Where
- 8 sites in United States
- Volunteers
- 71 people
- Sponsor
- Alcon Research
Cataract, Lens Opacities
Clinical Study to Investigate Outcomes of Trifocal Toric IOL POD FT in Asian Eyes
Prospective, controlled, single-surgeon, single-center clinical study to compare visual acuity outcomes to data obtained in a similar study by the same principal investigator on the trifocal IOL POD F (study no.
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- NCT03844828
- Testing
- IOL implantation experimental
- Where
- Philippines
- Volunteers
- 100 people
- Sponsor
- Beaver-Visitec International, Inc.
Cataract
Multicentric Clinical Investigation to Assess Safety and Performance of Lux HighAdd IOL
The study purpose is to demonstrate safety and performance of bilateral implantation of LuxHighAdd intraocular lens compared with the LuxGood Monofocal lens.
- Trial name
- HIGHADD (NCT06446817)
- Testing
- LuxHighAdd IOL, LuxGood IOL
- Where
- 3 sites in France
- Volunteers
- 57 people
- Sponsor
- Cutting Edge SAS
Cataract
Clinical Evaluation of the Performance of the enVista® Aspire™ (EA) Lens
A Prospective, Single-Center, Randomized Clinical Investigation to evaluate the safety and performance of the enVista® Aspire ™ (EA) intraocular lens (IOL) when compared to the MX60E monofocal IOL (control lens) and an IOL with a…
- Trial name
- NCT06479148
- Testing
- enVista® Aspire™, An IOL with a slightly extended depth of focus, MX60E
- Where
- Honduras
- Volunteers
- 27 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract
Capella Scientia Development Study
This study involves collecting biometry and aberration data using the next generation biometer, Unity DX.
- Trial name
- NCT06987474
- Testing
- Unity DX and SMARTCataract DX (SCDX) Biometer, IOLMaster 700 Biometer, Argos with Alcon Image Guidance Biometer
- Where
- 4 sites in India, Philippines and 1 more
- Volunteers
- 400 people
- Sponsor
- Alcon Research
Cataract Surgery
A Prospective Multicenter Study To Assess The Clinical Outcomes Of Current Phacoemulsification Approach To Cataract Extraction Versus The Micor System Device
The purpose of this research study is to evaluate the clinical outcomes of current phacoemulsification approaches to cataract extraction involving high-frequency thermogenic energy versus the use of the MICOR System device using…
- Trial name
- NCT05729477
- Testing
- miCOR System, Phaco Subject Cohort
- Where
- 6 sites in United States
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Cataract
A Post-Market Clinical Follow-Up on Safety and Performance of the Ophthalmic Viscoelastic Devices Eyefill SC and Eyefill MB
Prospective, Non-comparative, Post Market Clinical Follow Up Study to demonstrate safety and performance of Eyefill® S.C. and Eyefill® M.B. as viscoelastic devices for cataract surgery
- Trial name
- NCT06767917
- Testing
- Eyefill® S.C., Eyefill® M.B.
- Where
- 2 sites in Spain
- Volunteers
- 148 people
- Sponsor
- Bausch & Lomb GmbH
Eye Diseases, Postcataract Aphakia
Investigation of the Safety and Effectiveness of Monofocal Toric Intraocular Lens (IOL)
This study is a prospective, multicenter, randomized, double masked trial comparing an investigational Monofocal Toric intraocular lens (IOL) (PODEYE TORIC CYL 1.5 D) and a commercially available non-toric monofocal IOL.
- Conditions
- Eye Diseases, Postcataract Aphakia, Cataract, Lens Opacities
- Trial name
- NCT06399211
- Testing
- PODEYE TORIC Monofocal IOL, Alcon AcrySof SA60AT Monofocal IOL
- Volunteers
- 261 people
- Sponsor
- Beaver-Visitec International, Inc.
Cataract
Safety and Efficacy of the Bi-Aspheric Monofocal IOL
This is an observational, single-center, non-control, open-label post-marketing study. Patients implanted with an aspicio™ Monofocal Intraocular Lens will be scheduled for a follow-up visit at least 3 months after the surgery to…
- Trial name
- NCT06380478
- Testing
- aspicio Monofocal IOL
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- ICARES Medicus, Inc.
Macular Degeneration, Diabetic Retinopathy (DR)
Artificial Intelligence-assisted Diagnosis in Ophthalmology
This is a retrospective, multicenter, observational study designed to develop and validate an artificial intelligence (AI) system capable of detecting and classifying major ophthalmic diseases (glaucoma, cataract, diabetic…
- Conditions
- Macular Degeneration, Diabetic Retinopathy (DR), Glaucoma, Keratoconus
- Trial name
- AI-OPHTH-CR (NCT07497815)
- Testing
- No interventions
- Where
- 2 sites in Costa Rica
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Marisse Masis-Solano
Post Cataract Surgery
The TRIBECA Study (TRIessence/Byqlovi for Easier CAtaract Surgery)
A self-controlled, prospective clinical study of the safety, clinical efficacy, and patient acceptance of subconjunctival delivery of triamcinolone 40 mg/mL (Triesence) at the conclusion of cataract surgery or topical clobetasol…
- Trial name
- TRIBECA (NCT07276802)
- Testing
- Triamcinolone (Optional), control group
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Research Insight LLC
Cataract, Keratoconus
Clinical Study - ES 900 - 2020-2
The EYESTAR 900 with software version i9.5.1.0 includes new analysis functionality. Since its clinical performance cannot be assessed based solely on clinical literature as found in the Clinical Evaluation Report, further data…
- Trial name
- NCT04392349
- Testing
- Haag-Streit EYESTAR 900, Tomey CASIA 2, Oculus PENTACAM HR
- Where
- Switzerland
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Haag-Streit AG
Aphakia
Evaluation of Clareon Vivity/Vivity Toric
This study seeks to generate clinical data from subjects previously implanted with the Clareon Vivity/Vivity Toric Intraocular Lenses (IOLs) or Clareon Monofocal/Clareon Toric IOLs.
- Trial name
- NCT05852470
- Testing
- Clareon Vivity/Vivity Toric Extended Vision IOL, Clareon Monofocal/Clareon Toric IOL
- Where
- 7 sites in United States
- Volunteers
- 155 people
- Sponsor
- Alcon Research
Cataract Surgery, Ocular Infections
Efficacy of EPD-09-25 for Eyelid Hygiene Before and After Eye Surgery.
This is an interventional, open-label, two-arms clinical trial, randomized 1:1 (EPD treatment or no eyelid hygiene treatment) in patients scheduled for eye surgery (cataract surgery).
- Trial name
- NCT07418333
- Testing
- EPD Eyelid wipes
- Volunteers
- 100 people
- Sponsor
- VISUfarma SpA
Cataract Surgery
Post-Market Study on the Safety and Effectiveness of the OpHLINE OVD in Cataract Surgery
This post-market clinical study was designed to assess the safety and effectiveness of the OpHLINE Ophthalmic Viscosurgical Device (OVD) as an adjunct in cataract surgery.
- Trial name
- NCT07343973
- Testing
- Cataract Surgery by Phacoemulsification with Posterior Chamber Intraocular Lens Implantation (OpHLINE 1.4%), Cataract Surgery by Phacoemulsification with Posterior Chamber Intraocular Lens Implantation (OpHLINE 2%), Cataract Surgery by Phacoemulsification with Posterior Chamber Intraocular Lens Implantation (OpHLINE 3%)
- Where
- 2 sites in Spain
- Volunteers
- 69 people
- Sponsor
- i+Med S.Coop.
Cataract Surgery
Assessment of a Hand-held Femtosecond Laser to Perform Anterior Capsulorhexis During Cataract Surgery (Post-market Study)
The goal of this observationnal study is to supplement the data collected in the pre-market study and confirm the rate of capsular ruptures due to Rx (reducing its related confidence interval).
- Trial name
- PMCF_SEQ_Rx (NCT07362043)
- Testing
- Cataract surgery with Rx, a handheld femtosecond laser for anterior capsulotomy (CE-marked device used as intended)
- Where
- France
- Volunteers
- 446 people
- Sponsor
- Helix Surgical