Clinical trials: Cataracts
Cataract, Dry Eye
Efficacy of Topical Cyclosporine Versus Tears for Improving Visual Outcomes Following Multifocal IOL Implantation
The purpose of this study is to evaluate the efficacy on quality of vision and dry eye signs and symptoms in patients undergoing cataract surgery using the ReZoom® multifocal IOL.
- Trial name
- NCT00349583
- Testing
- Topical Cyclosporine, Tears
- Where
- United States
- Sponsor
- Innovative Medical
Cataract in Inflammatory Ocular Disorders
A Clinical Study to Assess the Efficacy and Safety of SED80 for Use in Cataract Surgery
Patients at least 40 years of age who are undergoing cataract surgery will be randomized to receive treatment with one of four groups of dexamethasone ophthalmic suspension or placebo eye drops to determine if the drops decrease…
- Trial name
- NCT04711213
- Testing
- Dexamethasone Dose 1, Dexamethasone Dose 2
- Where
- El Salvador
- Volunteers
- 60 people
- Sponsor
- iDrop, Inc.
Cataract
Visual Function With Contralateral AcrySof® ReSTOR® Aspheric SN6AD1 and SN6AD3
The objective of this study is to prospectively evaluate the visual parameters in a series of patients after phacoemulsification cataract surgery in a series of patients bilaterally implanted with the AcrySof® ReSTOR® Aspheric…
- Trial name
- NCT00710905
- Testing
- AcrySof ReSTOR Aspheric IOL models SN6AD1 and SN6AD3
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Alcon Research
Cataract, Lens Opacities
Comparison of ISOPURE and EYHANCE (Switzerland)
This is a prospective randomised open-label study with the aim to compare the visual performance of the premium monofocal Isopure IOL versus the extended depth of focus Eyhance® IOL after phaco-emulsification cataract surgery.
- Trial name
- PHY2301 (NCT05875922)
- Testing
- IOL implantation experimental (ISOPURE 1.2.3.), IOL implantation active comparator (TECNIS Eyhance)
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract, Lens Opacities
Clinical Study to Compare Visual Performance of Two Trifocal IOLs
Prospective, randomised, controlled, single-surgeon, single-center post-market clinical follow up study to compare the clinical outcomes of two trifocal IOLs with different material
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- PHY1702 (NCT03347981)
- Testing
- IOL implantation experimental, IOL implantation active comparator
- Where
- Spain
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract
Efficacy and Safety of Bromfenac Ophthalmic Solution in Cataract Surgery
Efficacy and Safety of Bromfenac Ophthalmic Solution in Cataract Surgery
- Trial name
- NCT00704418
- Testing
- Bromfenac
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Bausch & Lomb Incorporated
Cataracts
Clinical Investigation of Visual Function After Bilateral Implantation of Two Presbyopia-Correcting Trifocal Intraocular Lenses (IOL)
The purpose of this study is to clinically evaluate the visual performance of two commercially available presbyopia-correcting Trifocal IOLs.
- Trial name
- NCT02691741
- Testing
- AcrySof® IQ PanOptix™ Presbyopia-Correcting IOL, AT LISA® tri IOL
- Volunteers
- 215 people
- Sponsor
- Alcon Research
Cataract
Addressing of Efficacy and Safety of Femtosecond-laser Assisted Versus Manual Lens Fragmentation Procedure
This clinical study is a randomized, controlled, open, prospective, multi-centre, multi-surgeon post-market-clinical-follow-up study to investigate the impact of cataract grade on the efficacy and safety of femtosecond laser…
- Trial name
- NCT01971177
- Testing
- Femtosecond laser cataract surgery, Manual cataract surgery
- Where
- 2 sites in Czechia, India
- Volunteers
- 136 people
- Sponsor
- Technolas Perfect Vision GmbH
Cataract Surgery
Efficacy and Safety of Bromfenac Ophthalmic Solution
This is a safety and efficacy study of bromfenac ophthalmic solution
- Trial name
- NCT00585975
- Testing
- bromfenac ophthalmic solution
- Where
- United States
- Volunteers
- 568 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Cataract
Visual Outcomes of Subjects Bilaterally Implanted With ReSTOR Aspheric +4 vs. Tecnis or Acri.LISA
This is a study to compare visual outcomes of subjects bilaterally implanted w/ReSTOR to subjects bilaterally implanted with the Tecnis Multifocal Intraocular Lens (IOL) or Acri.LISA IOL
- Trial name
- NCT00721253
- Testing
- ReSTOR, Tecnis, Acri.LISA
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Cataracts
Low Cylinder Toric
Study evaluates the visual outcomes and patient satisfaction after implantation of a toric intraocular lens (IOL).
- Trial name
- NCT00732030
- Testing
- Toric IOL (SN60T3)
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Alcon Research
Cataract
Influence of Clearing Open-capsule Device on Refractive Predictability in Cataract Patients
CleaRing is intended to reduce posterior capsular opacification in cataract patients. The device is intended to be implanted together with standard posterior chamber IOL during cataract surgery.
- Trial name
- NCT04838730
- Testing
- Surgical procedure
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Hanita Lenses
Cataract, Glaucoma
Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)
This trial is a randomized study to evaluate the Bimatoprost Implant System used in combination with the SpyGlass IOL to Timolol Ophthalmic Solution in participants with mild to moderate open-angle glaucoma or ocular hypertension…
- Conditions
- Cataract, Glaucoma, Ocular Hypertension
- Trial name
- NCT07218796
- Testing
- Bimatoprost Implant System, SpyGlass IOL, Timolol Maleate Ophthalmic Solution, 0.5%
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- SpyGlass Pharma, Inc.
Open-Angle Glaucoma
A Study of the iStent in Combo With Cataract Surgery in Newly Diagnosed Open Angle Glaucoma or OH Patients.
The purpose of this study is to evaluate the safety and efficacy of the iStent trabecular micro-bypass stent in reducing intraocular pressure (IOP) in subjects with newly diagnosed open-angle glaucoma and subjects diagnosed with…
- Trial name
- NCT00326066
- Testing
- Glaucoma Surgery, cataract surgery only
- Where
- 9 sites in Austria, Germany and 3 more
- Volunteers
- 47 people
- Sponsor
- Glaukos Corporation
Cataract, Lens Opacities
Clinical Study to Evaluate Clinical Outcomes of LuxSmart IOL as Compared With LuxGood IOL
This study is a multicentric, prospective, randomised, controlled, post-market clinical follow up (PMCF) study to investigate safety, visual outcomes and contrast sensitivity after bilateral implantation of either LuxSmart IOLs…
- Trial name
- NCT06105190
- Testing
- Implantation of premium monofocal IOL, LuxSmart (device under investigation), Implantation of monofocal IOL, LuxGood (control device)
- Where
- 8 sites in Austria, Czechia and 4 more
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Cutting Edge SAS
Patients Having Undergone Unilateral Cataract Extraction and Implantation of a Monofocal
OPEN-LABEL, MULTI-CENTER, PHASE 1b/2a CLINICAL TRIAL DESIGNED TO EVALUATE THE SAFETY AND EFFICACY OF IONTOPHORETIC DEXAMETHASONE PHOSPHATE OPHTHALMIC SOLUTION IN PATIENTS HAVING UNDERGONE CATARACT SURGERY WITH IMPLANTATION OF A POSTERIOR CHAMBER INTRAOCULAR LENS (IOL)
To evaluate the safety and efficacy of ocular iontophoresis with dexamethasone phosphate ophthalmic solution, EGP-437®, using the EyeGate® II Drug Delivery System (EGDS) in patients having undergone cataract surgery with…
- Trial name
- NCT02571556
- Testing
- Experimental: Dexamethasone Phosphate Ophthalmic solution (40 mg/mL) delivered by ocular iontophoresis consisting of 4.0 mA-min at 1.5 mA
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Eyegate Pharmaceuticals, Inc.
Cataract
Calhoun Vision Light Adjustable Lens (LAL) in Subjects With Pre-Existing Corneal Astigmatism
The purpose is to evaluate the Calhoun Vision Light Adjustable Lens (LAL) and Light Delivery Device (LDD) for reducing astigmatism and improving uncorrected vision after implantation.
- Trial name
- NCT01496066
- Testing
- LAL (Light Adjustable Lens) and Light Deliver Device (LDD), Monofocal control IOL
- Where
- 17 sites in United States
- Volunteers
- 600 people
- Sponsor
- Calhoun Vision, Inc.
Cataract
Lenstec Softec HD Posterior Chamber Intraocular Lens Clinical Investigational Protocol
The objectives of this multi-center clinical investigation are to determine the safety and effectiveness of the Lenstec Softec HD Posterior Chamber intraocular lens (IOL) following one year of post-operative assessment.
- Trial name
- NCT00963742
- Testing
- Lenstec Softec HD IOL implantation
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Lenstec Incorporated
Dry Eye
Prospective Health Assessment of Cataract Patients' Ocular Surface
This study will determine the incidence and severity of dry eye in patients undergoing cataract surgery as determined by grade on the International Task Force (ITF) scale.
- Trial name
- NCT01016405
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Innovative Medical
Cataract
Bioequivalence of Eye Drops and Spray Administration of Vigamox
The study compares the amounts of Vigamox absorbed when administered as eye drops or in a spray form. Both administrations will be prior to patients undergoing elective cataract surgery and the aqueous samples will be analyzed by…
- Trial name
- NCT00666042
- Testing
- Vigamox - administration in spray form, Vigamox eye drops
- Where
- Israel
- Volunteers
- 16 people
- Sponsor
- Advanced Ophthalmic Pharma