Clinical trials: Cataracts
Cataract, Astigmatism
Patient Perception of Visual Distortions
The purpose of this study is to evaluate visual distortions reported by pseudophakic patients.
- Trial name
- NCT02203747
- Testing
- Administration of patient self-assessment
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Bilateral Cataract, Presbyopia
Symfony/Synergy IOL Combination Outcomes
Current visual outcomes expectations of cataract patients are similar to those of refractive surgery patients. Their desire is to be spectacle independent for far, intermediate and near vision activities.
- Trial name
- NCT05604781
- Testing
- Symfony & Synergy IOL combination
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- Center For Sight
Inflammation, Pseudophakia
Clinical Outcomes of Bromday (Bromfenac Ophthalmic Solution) 0.09% QD vs. Nevanac (Nepafenac Ophthalmic Suspension) 0.1%
This is a single-center, randomized, investigator-masked, parallel group, and active-comparator controlled study investigating the clinical outcomes for visual acuity and macular thickness after treatment with Bromday (bromfenac…
- Trial name
- NCT01310127
- Testing
- Bromfenac, Nepafenac
- Volunteers
- 23 people
- Sponsor
- Toyos Clinic
Cataract
Study of T-PRED(TM) Compared to Pred Forte(R) II
Study of T-PRED(TM) Compared to Pred Forte(R)
- Trial name
- NCT00854061
- Testing
- T-Pred, Pred Forte
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract, Presbyopia
Clinical Investigation of the Visual Outcomes and Safety of a Trifocal Intraocular Lens (IOL) in a Korean Population
The purpose of this study is to confirm the effectiveness of the investigational lens in a Korean population, especially for visual performance, quality of vision, and subject satisfaction with the visual outcome, as well as the…
- Trial name
- NCT03268746
- Testing
- AcrySof IQ PanOptix Multifocal IOL
- Where
- 4 sites in South Korea
- Volunteers
- 52 people
- Sponsor
- Alcon Research
Dry Eye Syndromes
A Study to Determine the Prevalence of Inflammatory Dry Eye Disease in Patients Prior to Cataract Removal
This study will evaluate the prevalence of inflammatory dry eye disease in patients prior to cataract surgery. No treatment is administered in this study.
- Trial name
- REVEAL (NCT01882413)
- Testing
- No intervention
- Where
- 6 sites in Canada
- Volunteers
- 204 people
- Sponsor
- Allergan
Aphakia, Presbyopia
Clareon PanOptix Pro vs. Clareon PanOptix - Study A
The purpose of this study is to evaluate the safety and effectiveness of Clareon™ PanOptix™ Pro Trifocal Intraocular Lens (IOL) compared to Clareon™ PanOptix™ Trifocal IOL.
- Trial name
- NCT06400745
- Testing
- CPO Pro IOL, CPO IOL, Cataract surgery
- Where
- 8 sites in United States
- Volunteers
- 87 people
- Sponsor
- Alcon Research
Cataract, Aphakia
Clareon Toric vs Eyhance Toric
The primary purpose of this study is to compare the Clareon/Clareon Toric Intraocular Lenses (IOLs) to the Eyhance/Eyhance Toric IOLs in binocular Best Corrected Distance Visual Acuity (BCDVA) at 3 months postoperative.
- Trial name
- NCT05481125
- Testing
- Clareon IOL, Clareon Toric IOL, Eyhance IOL
- Where
- 8 sites in United States
- Volunteers
- 203 people
- Sponsor
- Alcon Research
Aphakia, Corneal Astigmatism
Clinical Investigation of an AcrySof IQ PanOptix Toric Intraocular Lens
The purpose of this study is to evaluate the effectiveness and safety of the TFNT20 low cylinder power intraocular lens when implanted in the eye to replace the natural lens following cataract removal.
- Trial name
- NCT04542525
- Testing
- ACRYSOF IQ PanOptix Toric Trifocal IOL, Cataract surgery
- Where
- Japan
- Volunteers
- 32 people
- Sponsor
- Alcon Research
Cataract, Floppy Iris Syndrome
Intraoperative Floppy Iris Syndrome
An assessment of the surgical performance of DisCoVisc compared to Healon5 during cataract surgery with intraocular lens implantation where miotic/small pupils or intraoperative Floppy Iris Syndrome exists.
- Trial name
- NCT00711347
- Testing
- DisCoVisc, Healon5
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Alcon Research
Cataract
Mapracorat Ophthalmic Suspension for the Treatment of Ocular Inflammation Following Cataract Surgery
The objective of this clinical study is to compare the safety and efficacy of Mapracorat Ophthalmic Suspension, 3% to vehicle for the treatment of postoperative inflammation and pain following cataract surgery.
- Trial name
- NCT01230125
- Testing
- Mapracorat, Vehicle
- Where
- United States
- Volunteers
- 311 people
- Sponsor
- Bausch & Lomb Incorporated
Ocular Inflammation and Pain After Cataract Surgery
A Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of APP13007 to Treat Inflammation and Pain After Cataract Surgery
This is a Phase 2a, 2-part study (designated Parts A and B) that will evaluate APP13007 dose strength and dosing frequency in a randomized double-masked fashion for comparison to the respective matching vehicle placebo.
- Trial name
- NCT04089735
- Testing
- APP13007, 0.05%, APP13007, 0.1%
- Where
- 9 sites in United States
- Volunteers
- 165 people
- Sponsor
- Formosa Pharmaceuticals, Inc.
Cataract, Cystoid Macular Edema After Phacoemulsification
Effects of Bromfenac on Macular Thickness After Phacoemulsification Surgery
The goal of this clinical trial is to learn if bromfenac ophthalmic solution can prevent cystoid macular edema (CME) and reduce macular thickness in patients undergoing phacoemulsification surgery for cataract removal.
- Trial name
- NCT06785090
- Testing
- Bromfenac, Moxifloxacin 0.5% ophthalmic solution, Dexamethasone phosphate 0.1%
- Where
- Iraq
- Volunteers
- 87 people
- Sponsor
- Inas Abd
Cataracts
Clinical Investigation of AcrySof® IQ ReSTOR® +3.0 D Multifocal Toric Intraocular Lens (IOL)
The purpose of this study is to evaluate the safety and effectiveness of an investigational multifocal toric intraocular lens (IOL) compared to an FDA-approved multifocal IOL.
- Trial name
- NCT01424189
- Testing
- AcrySof® IQ ReSTOR® +3.0 D Multifocal Toric IOL, AcrySof® ReSTOR® Multifocal IOL Model SA60D3
- Volunteers
- 677 people
- Sponsor
- Alcon Research
Cataract
Effect of Blue Light Filtration on Visual Performance
The purpose of this study is to evaluate photostress recovery with blue light filter clip-on glasses among pseudophakes [ie, subjects in which the natural lens of the eye has been replaced with an artificial lens (intraocular…
- Trial name
- NCT01938989
- Testing
- Clear clip-on glasses, Blue light filter clip-on glasses
- Volunteers
- 158 people
- Sponsor
- Alcon Research
Cataract
Safety and Efficacy of OMS302 in Subjects Undergoing Unilateral Cataract Extraction With Lens Replacement (CELR)
The purpose of this study is to determine whether the use of OMS302 (the study drug) in individuals undergoing Cataract Extraction with Lens Replacement (CELR) surgery is safe and effective at maintaining an adequately dilated…
- Trial name
- NCT01193127
- Testing
- OMS302 Solution, OMS302 Mydriatic Solution, OMS302 Anti-inflammatory Solution
- Where
- 24 sites in United States
- Volunteers
- 223 people
- Sponsor
- Omeros Corporation
Dry Eye
Effects of Cataract Extraction Surgery and Limbal Relaxing Incision on Corneal Sensation and Dry Eye
This is a multicenter evaluation of the effects of the cataract extraction and limbal relaxing incisions (LRI) on corneal sensation and dry eye signs and symptoms.
- Trial name
- NCT01161771
- Testing
- Cataract Surgery and Limbal relaxing incision
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Allergan
Cataracts
Low Cylinder Toric
Study evaluates the visual outcomes and patient satisfaction after implantation of a toric intraocular lens (IOL).
- Trial name
- NCT00732030
- Testing
- Toric IOL (SN60T3)
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Alcon Research
Cataract
Evaluation of Quality of Vision and Spectacle Independence With the AcrySof® Panoptix® Intraocular Lens
This is a study to assess the spectacle independence and quality of vision of patients receiving the AcrySof® Panoptix® Intraocular lens (IOL) after uneventful cataract surgery.
- Trial name
- NCT04124952
- Testing
- Panoptix
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- SightTrust Eye Institute
Cerebrotendinous Xanthomatosis (CTX)
Cerebrotendinous Xanthomatosis (CTX) Prevalence Study
Iiopathic bilateral cataracts occur in many children with Cerebrotendinous Xanthomatosis (CTX) so the opportunity to use contact with health care providers in connection with pediatric cataract evaluation and treatment is a…
- Trial name
- NCT02638220
- Where
- 44 sites in United States
- Volunteers
- 442 people
- Sponsor
- Travere Therapeutics, Inc.