Clinical trials: Cataracts
Presbyopia, Cataract
The Effect of Cataract Extraction on the Contractility of Ciliary Muscle
The purpose of this study is to investigate the changes in the pilocarpine-induced ciliary body movement before and after cataract extraction in order to determine the effect of lens sclerosis on the ciliary muscle contractility.
- Trial name
- NCT00624039
- Testing
- UBM with pilocarpine in presbyopia
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Samsung Medical Center
Cataract
Yellow Versus White Study
Blue-light-filtering IOLs are implanted increasingly often in cataract surgery. Several studies examined the effect of blue-light-filters on contrast and colour vision. However, the study outcomes were varying.
- Trial name
- YeWhi (NCT00612781)
- Testing
- cataract surgery (Hoya AF-1 [UY] YA-60BB), cataract surgery (Hoya AF-1 [UV] VA-60BB lens)
- Where
- Austria
- Volunteers
- 24 people
- Sponsor
- Hospital Hietzing
Glaucoma
A Comparison Between Deep Sclerectomy and Trabeculectomy
Patients affected by medically uncontrolled open angle glaucoma will be randomised to either a non penetrating procedure (deep sclerectomy) or conventional trabeculectomy. The longterm efficacy (i.e.
- Trial name
- NCT00595855
- Testing
- trabeculectomy, deep sclerectomy
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University of Parma
to Compare the Effect of Two Types of IOLs, on the Incidence of Cystoid Macular Edema
The Effect of a Blue Light Filtering IOL
To compare the effect on blood retinal barrier disruption 3 and 12 months after implantation of either a blue light filtering intraocular lens(blue-filtering IOL) or an ultraviolet light filtering intraocular lens(UV-filtering…
- Conditions
- to Compare the Effect of Two Types of IOLs, on the Incidence of Cystoid Macular Edema, After Cataract Surgery
- Trial name
- NCT00571831
- Testing
- intraocular lens implantation
- Where
- Japan
- Volunteers
- 50 people
- Sponsor
- Showa University
Cataract
Absorption of Brimonidine Ophthalmic Solution in the Aqueous Humor of Cataract Patients
The purpose of this study is to obtain and assay human aqueous samples following pre-operative dosing with 0.1% Brimonidine Purite™ (pH 7.8) or with 0.15% Brimonidine Purite® (pH 7.2) from patients undergoing routine cataract…
- Trial name
- NCT00352807
- Testing
- Brimonidine Purite
- Where
- 4 sites in United States
- Volunteers
- 22 people
- Sponsor
- Indiana University
Cataract
Bioavailability of Bimatoprost Ophthalmic Solution in Human Aqueous.
The purpose of this study is to assay human aqueous for bimatoprost and the presence of any metabolites, especially prostaglandin analogs.
- Trial name
- NCT00355446
- Testing
- Bimatoprost 0.03%
- Where
- 4 sites in United States
- Volunteers
- 48 people
- Sponsor
- Indiana University
Epiretinal Membranes, Macular Holes
Blue-Blocking IOLs in Combined Surgery
Although commonly used in cataract surgery, the use of the blue light-filter IOLs in vitrectomy combined with cataract surgery has not been reported yet.
- Conditions
- Epiretinal Membranes, Macular Holes, Cataract
- Trial name
- NCT00537992
- Testing
- combined surgery
- Volunteers
- 60 people
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Cataract Surgery
Therapeutic Variables in Cataract Surgery
The purpose of this study is to compare patient outcomes in following cataract surgery in patients randomized to one of two surgical kits.
- Trial name
- NCT00407017
- Testing
- Gatifloxacin, Ketorolac LS, Pred Forte
- Where
- United States
- Sponsor
- Innovative Medical
Cataract
Aqueous Concentrations and PGE2 Inhibition of Ketorolac 0.4% vs. Bromfenac 0.09% in Cataract Patients
Evaluation of the aqueous concentrations of 2 topical NSAIDS as well as the PGE2 inhibition in human patients.
- Trial name
- NCT00347503
- Testing
- ketorolac 0.4%, bromfenac 0.09%
- Where
- United States
- Sponsor
- Innovative Medical
Cataract
Acular LS vs. Nevanac in Post op Inflammation Following Cataract Surgery
The purpose of this study is to compare the clinical outcomes, safety and efficacy in patients randomized to receive either ketorolac or nepafanac following cataract surgery.
- Trial name
- NCT00348582
- Testing
- Ketorolac, Nepafenac
- Where
- United States
- Sponsor
- Innovative Medical
Cataract, Dry Eye
Efficacy of Topical Cyclosporine Versus Tears for Improving Visual Outcomes Following Multifocal IOL Implantation
The purpose of this study is to evaluate the efficacy on quality of vision and dry eye signs and symptoms in patients undergoing cataract surgery using the ReZoom® multifocal IOL.
- Trial name
- NCT00349583
- Testing
- Topical Cyclosporine, Tears
- Where
- United States
- Sponsor
- Innovative Medical
Cataract
Intraocular Steroid After Cataract Surgery Study
The use of one dose of an antibiotic and steroid injected into the eye at the end of cataract surgery is as safe and effective as the post operative use of eyedrops after cataract surgery.
- Trial name
- NCT00478764
- Testing
- intraocular triamcinolone and gatifloxicin
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Dean Health System
Glaucoma, Cataract
Outcome of Small Pupil Phacotrabeculectomy in Persons With Glaucoma and Cataract
Small pupils are not uncommon in situations requiring surgical intervention for glaucoma and cataract. Inadequate binocular view during combined trabeculaectomy and glaucoma surgery needs to be overcome by additional iris…
- Trial name
- NCT00434707
- Volunteers
- 70 people
- Sponsor
- Aravind Medical Research Foundation
Cataract, Pseudophakia
Effect of Optic Edge Design in a Silicone Intraocular Lens on Posterior Capsule Opacification
Purpose: To compare the posterior capsule opacification (PCO) inhibiting effect of the sharp posterior optic edge design of the Clariflex silicone intraocular lens (IOL) with that of the double-round edge design of the SI40…
- Trial name
- NCT00428363
- Testing
- Cataract surgery with implantation of an intraocular lens
- Where
- Austria
- Volunteers
- 52 people
- Sponsor
- Medical University of Vienna
Cataract
Ketorolac vs. Steroid in the Prevention of CME
Evaluate if the incidence of sub clinical CME can be significantly reduced by use of peri-operative Acular LS plus Pred Forte when compared with Pred Forte alone in normal cataract patients.
- Trial name
- NCT00348244
- Testing
- Ketorolac, Prednisolone Acetate
- Where
- United States
- Sponsor
- Innovative Medical
Cataract, Pseudophakia
Wavefront Analisys and Contrast Sensitivity of Spherical and Aspherical Intraocular Lenses
Purpose:To compare visual performance, total and high order wavefront aberrations (coma, spherical aberration and other terms) and contrast sensitivity in eyes implanted with one monofocal aspheric intraocular lens (IOL) and two…
- Trial name
- NCT00347243
- Testing
- phacoemulsification (cataract surgery)
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Cataract
Efficacy of Honan Balloon in Intraocular Pressure Reduction Before Phacoemulsification
-Does Honan balloon reduce intraocular pressure preoperatively?
- Trial name
- NCT00386438
- Testing
- Honan balloon application
- Where
- Thailand
- Sponsor
- Chulalongkorn University
Idiopathic Epiretinal Membrane, Cataract
Surgical Removal of Idiopathic Epiretinal Membrane With and Without the Assistance of Indocyanine Green.
It was the aim of the present study to prospectively compare the functional and morphological outcome of idiopathic epiretinal membrane surgery with and without the assistance of Indocyanine green (ICG).
- Trial name
- NCT00376857
- Testing
- Surgery with and without the aid of Indocyanine Green (ICG)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University of Regensburg
Cataract Extraction
Surgical Outcomes After Routine Cataract Extraction & Implantation of a Conventional or Spheric Intraocular Lens
To determine quality of vision post cataract extraction and intraocular lens (IOL) implantation of 2 different acrylic intraocular lenses: Acrysof® Single-Piece IOL and Acrysof® WF, through evaluation of contrast sensitivity…
- Trial name
- NCT00366496
- Testing
- Acrysof single piece (SA60AT), Acrysof IQ (SN60WF)
- Volunteers
- 30 people
- Sponsor
- Medical University of South Carolina
Cataract Extraction
Comparison of the Performance of the Infiniti Vision and the Series 20000 Legacy Phacoemulsification Systems
To compare the efficiency of the Infiniti vision system and the Series 20000 Legacy System phacoemulsification units during routine cataract extraction.
- Trial name
- NCT00366665
- Testing
- Legacy 20000, Infinit system
- Volunteers
- 30 people
- Sponsor
- Medical University of South Carolina