Clinical trials: Cataracts Senile
Senile Cataract, Epiretinal Membrane
Clareon Intraocular Lens Stability in Vitrectomy Patients: CLOVE Study
This prospective randomized controlled trial will be conducted to investigate Clareon intraocular lens (IOL) stability in vitrectomy patients. The investigator plans to target the patients undergoing cataract surgery.
- Conditions
- Senile Cataract, Epiretinal Membrane, Vitreous Hemorrhage
- Trial name
- NCT06383754
- Testing
- Clareon, Tecnis 1
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Senile Cataract
Safety and Performance of Hydrophobic and Hydrophilic Intraocular Lenses After Bilateral Cataract Surgery
Subjects who had a bilateral age-related cataract surgery with the IOLs AT ELANA 841P and AT LISA tri 839MP will be contacted and invited to attend a postoperative visit more than one year after the surgery
- Trial name
- NCT06192901
- Where
- El Salvador
- Volunteers
- 8 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract
Small RNA tRF-31 Changes in Patients With Age-Related Cataract
The goal of this observational study is to evaluate the expression characteristics and clinical relevance of the tRF-31/HIPK2 signaling axis in adults over 18 years old with age-related cataract (ARC).
- Trial name
- NCT07672899
- Testing
- Biospecimen collection (Anterior lens capsule)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cataract Senile, Glaucoma, Open Angle
A Fellow Eye Comparative Study of the Aquea Intracanalicular Glaucoma Micro-coil Stent and the Alcon Hydrus Glaucoma Microstent
The purpose of this research study is to compare the safety and effectiveness of the Aquea Intracanalicular Glaucoma Stent to the Alcon Hydrus Glaucoma Microstent for the reduction of intraocular pressure (IOP) in patients with…
- Trial name
- NCT07836855
- Testing
- Aquea Zealix™, Hydrus® Microstent
- Where
- Honduras
- Volunteers
- 16 people
- Sponsor
- Aquea Health, Inc.
Cataract Senile
Anterior Chamber Illumination in Cataract Surgery for Eyes With Poor Red Reflex
With a poor red reflex, it is difficult to see the anterior capsule and continuous curvilinear capsulorhexis (CCC) margin, sometimes resulting in decentered CCC or radial tearing of the anterior capsule.
- Trial name
- NCT04220138
- Testing
- Anterior chamber illumination in cataract surgery
- Where
- Egypt
- Volunteers
- 53 people
- Sponsor
- University of Alexandria
Cataract, Dry Eye Syndromes
Optimization of the Ocular Surface Prior to Cataract Surgery Using PROKERA
The purpose of the study is to assess whether PROKERA can sufficiently stabilize the ocular surface prior to cataract surgery and improve post operative outcomes patients with moderate to severe dry disease.
- Conditions
- Cataract, Dry Eye Syndromes, Cataract Senile, Dry Eye
- Trial name
- NCT05148507
- Testing
- PROKERA
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Jeff Wongskhaluang
Cataract Senile, Intraocular Lens Complication
Visual Outcomes Following Bilateral Implantation of the Vivity Toric Intraocular Lens
The objective of this study was to evaluate the clinical and patient reported outcomes after bilateral implantation of the AcrySof™ IQ Vivity™ Toric intraocular lens.
- Trial name
- NCT06196593
- Testing
- AcrySof™ IQ Vivity™ Toric intraocular lens
- Where
- Malaysia
- Volunteers
- 30 people
- Sponsor
- LEC Eye Centre
Cataract Senile
Eyhance Autorefraction Study
Since 2018, the Tecnis Eyhance ICB00 lens (Johnson\&Johnson Vision, AMO Germany GmbH) was introduced, which is a monofocal IOL which has the ability of extended depth of focus improving intermediate vision without the photic…
- Trial name
- NCT04572334
- Testing
- Auto and Subjective Refraction
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Cataract
Collaborative Italian-American Clinical Trial of Nutritional Supplements and Age-related Cataract (CTNS)
The Collaborative Italian-American Clinical Trial of Nutritional Supplements and Age-related Cataract (CTNS) is a 13-year study designed primarily to evaluate the safety and efficacy of a vitamin-mineral supplement (Centrum)…
- Trial name
- CTNS (NCT00309387)
- Testing
- Centrum
- Where
- Italy
- Volunteers
- 1,020 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Cataract, Age-related Cataract
Optometric Follow-up After Cataract Surgery
This study will investigate the effectiveness of an optometric follow up of cataract surgery versus an ophthalmic surgeon follow up. It will investigate patient satisfaction,safety and cost.
- Trial name
- NCT04163926
- Testing
- Intervention Group cataract follow up, Usual Care consultant follow up
- Sponsor
- Queen's University, Belfast
Cataract Senile
Safety and Effectiveness of an Hydrophilic Acrylic Intraocular Lens
Evaluation of the clinical safety and effectiveness of hydrophilic acrylic intraocular lens
- Trial name
- NCT04789538
- Testing
- monofocal lens
- Where
- France
- Volunteers
- 328 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract Senile, Presbyopia
RayOne EMV Mini-monovision - Efficiency and Safety of 3 Grades of Mini-monovision
Aim:To determine the effectiveness and subjective satisfaction of patients with bilateral cataract surgery and implantation of intraocular lens (IOL) RayOne EMV with enhanced optic, using different degrees of mini-monovision (up…
- Trial name
- EMV (NCT05417633)
- Testing
- intraocular lens - RayOne EMV (Rayner Surgical GmbH,Berlin, Deutschland)
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- Somich, s.r.o.
Intraocular Pressure, Cataracts Senile
Intraocular Pressure Variation by Pneumatic Tonometer Before and After Phacoemulsification
The objective of this study is to evaluate the IOP variation before and 30 days after performing phacoemulsification through pneumatic tonometry, in addition to evaluating the factors possibly related to this variation.
- Trial name
- IPOFACO (NCT03016507)
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- VER Excelência em Oftalmologia
Dry Eye Disease, Meibomian Gland Dysfunction
Preoperative iLux on Cataract Surgery Derived Dry Eye Disease Due to Meibomian Gland Dysfunction
This prospective study will investigate the effect of pre-operative Systane iLux system administration in treated cataract induced dry eye disease.
- Conditions
- Dry Eye Disease, Meibomian Gland Dysfunction, Cataract Senile, Dry Eye Syndromes
- Trial name
- NCT06483750
- Testing
- Systane iLux Treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- George Washington University
Cataract Senile
Comparision of Visual Outcomes and Patient Satisfaction Between Two Diffractive Trifocal Intraocular Lenses
The purpose of the present study was to compare the clinical outcomes such as visual function, refraction errors and visual quality of patients undergoing cataract surgery with implantation of two different models of diffractive…
- Trial name
- NCT04655274
- Testing
- The Quality of Vision questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Akdeniz University
Cataract Senile
Clinical Evaluation of the Bioli IOL Delivery System (BIOLI-D)
Cataract surgery is one of the most frequent surgeries carried out in the world. After cataract extraction an intraocular lens (IOL) is implanted in order to compensate for the crystalline lens power and correct patient's vision.
- Trial name
- NCT05790993
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- AST Products, Inc.
Age-related Cataract
Metabo-lipidomics of the Ocular Surface for Cataract Surgery
Cataract is the world's leading cause of blindness, the treatment of which, exclusively surgical, offers excellent results in terms of visual recovery.
- Trial name
- CATARACTOMIQUE (NCT05802550)
- Testing
- Ocular Surface Disease Index, Interferometry, Oxford score
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Tours
Cataract Senile
Predicting the Lens Capsular Bag Size Using Pre-operative Biometry
Aim of this study is to assess whether a high-resolution scan of the crystalline lens before surgery may be helpful in predicting post-operative capsule bag diameter.
- Trial name
- NCT05578339
- Testing
- Biometry
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Cataract Senile, Pseudophakia
Tecnis Eyhance Versus Rayner RayOne Study
Cataract surgery involves replacing milky lens with a plastic intraocular lens. This plastic lens can be either monofocal (fixates for distance or near without glasses), extended depth of focus (EDOF)(fixates for intermediate and…
- Trial name
- NCT04175951
- Testing
- Intraocular lens
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Brighton and Sussex University Hospitals NHS Trust
Age Related Cataracts
Intraindividual Comparison of EMO IOLs
The investigational devices are approved intraocular lenses (IOLs) intended to be implanted after phacoemulsification in individuals suffering from age-related cataract with the need of cataract surgery.
- Trial name
- EMO (NCT05822089)
- Testing
- phacoemulsification and intraocular lens implantation
- Where
- Austria
- Volunteers
- 461 people
- Sponsor
- Medical University of Vienna