Clinical trials: Cathartics
Chronic Idiopathic Constipation
A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adults
The purpose of this study is to evaluate a daily dose of BLI400 Laxative for safety and efficacy versus lubiprostone in constipated adults.
- Trial name
- NCT02481947
- Testing
- BLI400 Laxative, Lubiprostone
- Where
- 50 sites in United States
- Volunteers
- 459 people
- Sponsor
- Braintree Laboratories
Colon Cancer, Colon Polyp
Comparison of Two Preparations for the Study of the Colon Through Colonoscopy
Compare the quality of bowel preparation between two groups of patients, who will undergo two different preparations: 1. Moviprep + diet; 2. Plenvu + diet
- Conditions
- Colon Cancer, Colon Polyp, Colon Adenoma, Colon Rectal Cancer
- Trial name
- NCT04497935
- Testing
- PLENVU, MoviPrep
- Where
- Portugal
- Volunteers
- 613 people, healthy volunteers welcome
- Sponsor
- Unidade Local de Saúde do Alto Ave, EPE
Hip Fractures
What Laxative Should be Used After Hip Fracture Surgery?
To conduct a randomized clinical trial to determine how best to prevent constipation after hip fracture surgery using laxatives.
- Trial name
- NCT06455813
- Testing
- Bisacodyl, Macrogol 3350 and electrolytes, A combination of macrogol 3350 and electrolytes and bisacodyl
- Where
- 2 sites in Denmark
- Volunteers
- 375 people
- Sponsor
- Odense University Hospital
Bowel Preparation for Colonoscopy
Split Dose Pico-Salax + Bisacodyl vs. PEG Split Dose
The objective of this study is to compare the efficacy, safety and tolerability of two bowel preparations for colonoscopy - split dose Polyethylene Glycol-Based Lavage and Pico-Salax plus Bisacodyl - with a specific emphasis on…
- Trial name
- BP (NCT01415687)
- Testing
- Polyethylene Glycol-Based Lavage, Pico-Salax (Magnesium Citrate) plus Bisacodyl
- Where
- 2 sites in Canada
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Constipation
A Pilot Study of BLI801 Laxative in Adults Experiencing Non-Idiopathic Constipation
The objective of this study is to evaluate BLI801 laxative in adults experiencing non-idiopathic constipation.
- Trial name
- NCT02820714
- Testing
- BLI801 Laxative
- Where
- 3 sites in United States
- Volunteers
- 16 people
- Sponsor
- Braintree Laboratories
Pelvic Organ Prolapse, Prolapse
Pre-operative Bowel Preparation Prior to Minimally Invasive Sacral Colpopexy
Prior to surgery, gynecologists and urogynecologists have routinely prescribed preoperative mechanical bowel preparations in attempts to decrease the risk of infection, while also providing easier bowel manipulation and better…
- Trial name
- NCT01805310
- Testing
- Bowel preparation, No bowel preparation
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Halina M Zyczynski, MD
Severe Pain
A Non-interventional, Observational Study for Targinact® Treatment in Patients With Severe Pain.
This non-interventional, observational study evaluates the efficacy of Targinact with regard to pain relief in daily clinical practice in Belgium compared to the previous analgesic treatment.
- Trial name
- NCT01983137
- Testing
- Targinact® (oxycodone/naloxone)
- Where
- Belgium
- Volunteers
- 1,338 people
- Sponsor
- Mundipharma CVA
Colonoscopy Preparation
Single Dose Versus Split Dose Polyethylene Glycol-based Colonic Lavage for Colonoscopy
Proper bowel cleansing prior is an essential requirement for the conduct of colonoscopy. However, due to the nature of cleansing process, the ideal bowel cleansing preparation remains elusive.
- Trial name
- NCT01610856
- Testing
- Polyethylene Glycol
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Colorectal Disorders
The Use of Osmotic Laxatives Versus Macrogol for Bowel Preparation in Patients Undergoing Colonoscopy
The gold standard of colorectal examination is colonoscopy. One of the main purposes of colonoscopy is detecting bowel neoplasms. Right now there are several methods the bowel preparation for the colonoscopy.
- Trial name
- CLEAN (NCT04225793)
- Testing
- Eziklen®, MoviPrep
- Where
- Russia
- Volunteers
- 98 people
- Sponsor
- Russian Society of Colorectal Surgeons
Massage
Massage With Senna-based Laxatives Versus Senna-based Laxatives in Managing Overflow Retentive Stool Incontinence
This study aimed to evaluate the effect of abdominal massage with senna-based laxative in managing overflow retentive stool incontinence in pediatrics.
- Trial name
- NCT04273295
- Testing
- Abdominal massage
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- South Valley University
Constipation
Laxative Properties of Microencapsulated Lipid (Constipation Study)
The present study seeks to build on these observations to assess whether in principle, fat containing microcapsules might help patients experiencing constipation in association with weight loss interventions (including GLP-1…
- Trial name
- NCT05324241
- Testing
- Fat Microcapsules
- Where
- Ireland
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Colonoscopy Preparation
PEG Versus PEG+Bisacodyl Versus Sennosides for Colon Cleansing Before Colonoscopy
Background: Polyethylene glycol (PEG) solution has been proven to be effective for large bowel cleansing prior to colonoscopy in children.
- Trial name
- NCT01531140
- Testing
- polyethylene glycol +Bisacodyl, Polyethylene glycol, Sennosides
- Where
- 2 sites in Poland
- Volunteers
- 240 people
- Sponsor
- Medical University of Warsaw