Clinical trials: Catheter Ablation, active
Non-Small Cell Lung Cancer, Pulmonary Metastases
Pulsed Field Ablation for the Treatment of Malignant Lung Tumors
This prospective, single-center, single-arm exploratory study will evaluate the safety and effectiveness of a pulsed field ablation system and a single-use pulsed field ablation catheter for the treatment of malignant lung…
- Trial name
- NCT07889297
- Testing
- Pulsed Field Ablation System and Single-Use Pulsed Field Ablation Catheter
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Shanghai Chest Hospital
Atrial Fibrillation, Atrial Arrhythmia
Clinical and Healthcare Economic OutcoMes From ReAl-worlD Use in Europe of an AI Software During AF Ablation
The goal of this Observational Prospective Multi-center Study is to observe the acute and long-term safety and performance outcomes after spatiotemporal dispersion-based AF/AT ablation utilizing the Volta Medical AI software in…
- Conditions
- Atrial Fibrillation, Atrial Arrhythmia, Arrhythmias, Cardiac
- Trial name
- COMRADE-AI (NCT06083012)
- Testing
- Cardiac mapping
- Where
- 7 sites in France, Germany
- Volunteers
- 186 people
- Sponsor
- Volta Medical
Atrial Fibrillation (AF)
Efficacy and Safety of Intravenous + Oral Vs. Oral Amiodarone in Preventing Recurrence After Catheter Ablation in Patients with Persistent Atrial Fibrillation
This study aims to investigate the efficacy and safety of intravenous combined with oral amiodarone in preventing atrial fibrillation (AF) recurrence after catheter ablation in patients with persistent atrial fibrillation.
- Trial name
- NCT06742866
- Testing
- Amiodarone Injection, Sodium Chloride Injection 0.9%
- Where
- China
- Volunteers
- 418 people
- Sponsor
- Shanghai Chest Hospital
Paroxysmal Atrial Fibrillation
Catheter Ablation Using a Novel Navigation and Imaging System
The objective of the ENVIsIoN study is to collect data on the use of the VERAFEYE navigation and imaging system in patients indicated to undergo a catheter ablation procedure for the treatment of Paroxysmal Atrial Fibrillation…
- Trial name
- ENVIsIoN (NCT06895187)
- Testing
- VERAFEYE System
- Volunteers
- 100 people
- Sponsor
- LUMA Vision Ltd.
Ventricular Tachycardia
Catheter Ablation of Haemodynamically Not-tolerated Electrical Storm in Structural Heart Disease
This is a multi-center, parallel-group, randomized, open-label trial evaluating the clinical outcome and efficacy of emergency catheter ablation versus conventional stepped-care strategies in patients with haemodynamically…
- Trial name
- NCT06455020
- Testing
- Catheter ablation, Stepped-care strategies
- Where
- 4 sites in China
- Volunteers
- 96 people
- Sponsor
- Beijing Anzhen Hospital
Atrial Fibrillation (Paroxysmal), Paroxysmal AF
3-Dimensional Mapping System: The PULSTAR II Study
### Study Overview Study Name In simple terms, this study involves using a new device to treat a heart condition called "Paroxysmal Atrial Fibrillation." Sponsor The study is sponsored by a company called Shanghai Shangyang…
- Conditions
- Atrial Fibrillation (Paroxysmal), Paroxysmal AF, Pulsed Field Ablation
- Trial name
- PAF (NCT07586176)
- Testing
- Nanosecond pulsed electric field ablation system; Cardiac Pulsed Electric Field Ablation Catheter
- Where
- China
- Volunteers
- 152 people
- Sponsor
- Shanghai Shangyang Medical Technology Co., Ltd.
Atrial Fibrillation (AF)
Discontinuation of Anticoagulation With Intensive Rhythm Monitoring in Post-ablation Patients With Atrial Fibrillation
DIAMOND-AF is a multicenter, randomized, open-label trial evaluating whether discontinuing oral anticoagulation after successful atrial fibrillation ablation can reduce bleeding risk without increasing death or thromboembolism…
- Trial name
- DIAMOND-AF (NCT06871228)
- Testing
- NOAC discontinuation, NOAC continuation, Smartwatch single-lead ECG monitoring
- Where
- 22 sites in China
- Volunteers
- 4,100 people
- Sponsor
- Beijing Anzhen Hospital
Paroxysmal Atrial Fibrillation (PAF), Persistent Atrial Fibrillation
Outcomes of an Optimized Workflow With PulseSelect Pulsed Field Ablation (PFA) System in Paroxysmal and Persistent Atrial Fibrillation
The NEXT PULSE study is a pre-market, prospective, multi-center, non-randomized, interventional clinical study. Adult subjects with symptomatic paroxysmal or persistent AF who provided consent will be enrolled and treated with…
- Trial name
- NEXT PULSE (NCT07575828)
- Testing
- PulseSelect Pulse Field Ablation (PFA) System
- Volunteers
- 320 people
- Sponsor
- Medtronic Cardiac Ablation Solutions
Ventricular Tachycardia (VT), Catheter Ablation
Using Non-Invasive Mapping To Eliminate Structural Heart Disease Ventricular Tachycardia
Ventricular tachycardia (VT) is an abnormal and dangerous heart rhythm affecting the lower chambers of the heart (the ventricles).
- Trial name
- UNITE-VT (NCT07759427)
- Testing
- VIVO-assisted mapping
- Where
- 3 sites in United Kingdom
- Volunteers
- 110 people
- Sponsor
- University of Warwick
Atrial Fibrillation
Artificial Intelligence Guided Patient Selection for Atrial Fibrillation Catheter Ablation: Randomized Clinical Trial (AI-PAFA Trial)
Atrial fibrillation (AF) is a major cardiovascular disease with a prevalence of 1.7% of the total population in Korea, associated with 25% of ischemic stroke and 30% of heart failure, and is a major cardiovascular disease that…
- Trial name
- NCT04997824
- Testing
- Artificial Intelligence-based atrial fibrillation catheter ablation, Medical Therapy
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Yonsei University
Atrial Fibrillation (AF), Atrial Fibrillation Catheter Ablation
The COMBINE-AF Trial
The goal of this clinical trial is to test if a more complete ablation procedure works better than the standard procedure for people with long-lasting persistent atrial fibrillation (AF).
- Trial name
- COMBINE-AF (NCT07633509)
- Testing
- Linear ablation of mitral isthmus and tricuspid isthmus, Ethanol, Radiofrequency Ablation Catheter
- Where
- 3 sites in China
- Volunteers
- 430 people
- Sponsor
- Yunlong Wang
Atrial Fibrillation, Atrial Fibrillation Recurrent
Atrial Fibrillation Patients Treated With Catheter Ablation
This is a single-center prospective observational cohort study of atrial fibrillation patients treated with radiofrequency ablation.
- Trial name
- NCT05266144
- Testing
- radiofrequency ablation
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking Union Medical College Hospital
Atrial Fibrillation, Obesity & Overweight
Effect of Tirzepatide on Recurrence of Atrial Fibrillation After Catheter Ablation in Obese Patients
Obese patients with atrial fibrillation (AF) have a high recurrence rate after catheter ablation, even at experienced centers. Weight reduction improves post-ablation outcomes, but lifestyle measures alone are difficult to…
- Conditions
- Atrial Fibrillation, Obesity & Overweight, Catheter Ablation
- Trial name
- TEAR-AF (NCT07715929)
- Testing
- Tirzepatide, Structured Lifestyle Intervention
- Volunteers
- 710 people
- Sponsor
- Yunlong Wang
Hypertension
Sympathetic Mapping/ Ablation of Renal Nerves Trial
To evaluate the safety and efficacy of targeted renal sympathetic denervation using SyMapCath I® and SYMPIONEER S1® Stimulator/ Generator in patients with essential hypertension for at least 6 months of the disease history and…
- Trial name
- SMART (NCT02761811)
- Testing
- SyMapCath I™ catheter and SYMPIONEER S1™ Stimulator/Generator
- Where
- 15 sites in China
- Volunteers
- 220 people
- Sponsor
- SyMap Medical (Suzhou), Ltd.
Atrial Fibrillation
Prospective Study on the Effectiveness and Safety of Bi-polar Pulse-field Tip-catheter Ablation for Atrial Fibrillation in China（POTENTIAL-AF）
POTENTIAL-AF is a prospective, multicentre, observational registry study evaluating the real-world effectiveness and safety of bi-polar pulse-field tip-catheter ablation (PFA) for atrial fibrillation (AF) in China.
- Trial name
- POTENTIAL-AF (NCT07627685)
- Testing
- Bi-polar Pulse-field Ablation (PFA) - LEAD-PFA System with PulsedFA catheter
- Where
- China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Beijing Anzhen Hospital
Atrial Fibrillation (AF)
Measuring Local Potentials in PFA. MULTI PFA (EU)
The study is a prospective, multi-center, exploratory, observational study with the ECGenius® System and the PFAnalyzer software module in PFA cases using the Affera Sphere 9, FaraWave, PulseSelect, Volt or VariPulse PFA systems.
- Trial name
- MULTI PFA (NCT07379697)
- Volunteers
- 30 people
- Sponsor
- CathVision ApS
Essential Hypertension
To Evaluate the Safety and Efficacy of a Single-Use IVUS Ablation for Primary Hypertension
This is a prospective, multicenter, blinded, randomized controlled clinical trial designed to evaluate the safety and efficacy of a single-use intravascular ultrasound ablation catheter and ultrasound ablation system in the…
- Trial name
- NCT07051811
- Testing
- Intravascular Ultrasound Ablation Therapy, Renal Artery Angiography
- Where
- 18 sites in China
- Volunteers
- 213 people
- Sponsor
- Lepu Medical Technology (Beijing) Co., Ltd.
Atrial Fibrillation Paroxysmal
The Effect of Pulse Field Ablation on Atrial Mechanics in Catheter Ablation of Paroxysmal Atrial Fibrillation
The goal of this clinical trial is to compare the effect of pulmonary vein isolation on atrial function between pulse-field and cryoablation in patients over the age of 18 with paroxysmal atrial fibrillation.
- Trial name
- PF-MRI (NCT06557876)
- Testing
- Pulmonary vein isolation by pulse field ablation, Pulmonary vein isolation by cryoablation
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Atrial Fibrillation
Safety and Performance of the SpherePVI™ Catheter to Treat Paroxysmal Atrial Fibrillation
A prospective, single-arm, single-center study to evaluate the safety, performance, and effectiveness of the SpherePVI™ Catheter for treating paroxysmal AF.
- Trial name
- SpherePVI (NCT05144503)
- Testing
- SpherePVI™ Catheter
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Medtronic Cardiac Ablation Solutions
Myocarditis, Ventricular Arrythmia
Role of Endomyocardial Biopsy and Aetiology-based Treatment in Patients With Inflammatory Heart Disease in Arrhythmic and Non-arrhythmic Clinical Presentations: an Integrated Approach for the Optimal Diagnostic and Therapeutic Management
Myocarditis is a complex inflammatory disease, usually occurring secondary to viral infections, autoimmune processes or toxic agents.
- Conditions
- Myocarditis, Ventricular Arrythmia, Inflammatory Cardiomyopathy, Genetic Predisposition
- Trial name
- MYOCAR (NCT04521790)
- Testing
- support treatment, cardiac medical treatment, aetiology-specific treatment, device implant, arrhythmia ablation
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Scientific Institute San Raffaele