Clinical trials: Catheter Infection
Central Line-associated Bloodstream Infections
Impact of Disinfectant Caps on Nosocomial CLABSI
In a worldwide, one-day, prospective point-prevalence study, a prevalence of 15.1% for hospital-acquired central line-associated bloodstream infections (HA-CLABSI) was determined in 13,796 patients across 1,265 intensive care…
- Trial name
- NCT07430215
- Testing
- use of desinfection caps, sterile catheter cap
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- BDH-Klinik Hessisch Oldendorf
Vascular Access Complication, Vascular Access Related Infection
Arrow Chloragard Peripherally-Inserted Central Catheters (PICC) Study
A prospective study evaluating the timing, incidence and relationship of commonly occurring complications related to the use of peripherally-inserted central catheters.
- Trial name
- NCT03019302
- Testing
- Arrow PICC with Chloragard Technology
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Teleflex
Catheter-related Bloodstream Infection
SQ53 Disinfectant Wipes for Prevention of CRBSI
SQ53 is a novel antimicrobial, sporicidal solution that is based on a platform of quaternary ammonium chloride compounds. It has been tested against a wide range of bacteria, viruses, spores and fungal pathogens.
- Trial name
- NCT04822467
- Testing
- SQ53 Wipe, Ethanol Wipe
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- The Cleveland Clinic
Kidney Transplant; Complications, Kidney Transplant Infection
Early vs Late Urinary Catheter Removal After Renal Transplantation
The purpose of this study is to compare frequency of UTI, urine leak and need for reoperation in patients after renal transplant with early or delayed Foley catheter removal.
- Conditions
- Kidney Transplant; Complications, Kidney Transplant Infection, Urinary Fistula, Urinary Tract Infections
- Trial name
- ELUCATR (NCT04815954)
- Testing
- Urinary catheter removal
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Medical University of Warsaw
Bacteriuria
A Pilot Study To Assess The Impact Of A Camstent Coated Catheter On Clinical Bacteriuria
A Pilot Study To Assess The Impact Of A Camstent Coated Catheter On Clinical Bacteriuria when compared to an uncoated catheter. Each participant will take part in the trial from the time the participant signs the informed consent…
- Trial name
- CAM-SPC-001 (NCT04658719)
- Testing
- Camstent Coated Catheter, Standard Care
- Volunteers
- 30 people
- Sponsor
- Camstent Ltd.
Septicemia
Study to Evaluate the Effectiveness of the Initial Specimen Diversion Device When Collected Through Peripheral Intravenous Catheters
This is a randomized, open label study to evaluate the Initial Specimen Diversion Device (ISDD) in reducing the contamination rate in blood culture analysis.
- Trial name
- NCT02093494
- Testing
- Initial Specimen Diversion Device (ISDD), Lab standard practice (LSP), Peripheral Intravenous Catheters (PIVC)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Magnolia Medical Technologies, Inc.
Intensive Care
Novel Device for Reducing Catheter-Related Infections
This study is a pilot study of the safety, tolerability and efficacy of an investigational central venous catheter device used in conjunction with a standard central venous catheter.
- Trial name
- NCT00878683
- Testing
- silicone catheter boot
- Sponsor
- University of Kansas
Central Venous Catheter Thrombosis, Central Venous Catheter Associated Bloodstream Infection
t-PA Prophylaxis to Prevent Catheter-associated Thrombosis and Infection
The purpose of this pilot study is to test feasibility of concept, consent and enrollment rates, and mechanics of study designed to assess if intra-catheter dwells of tissue plasminogen activator (t-PA) is effective in decreasing…
- Trial name
- TOPCAT (NCT03672006)
- Testing
- alteplase (recombinant t-PA), Heparin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical College of Wisconsin
Central Line-associated Bloodstream Infection (CLABSI), Catheter-related Bloodstream Infection
Effect of Vancomycin After Catheter Replacement
Randomized controlled trial of the effect of a single-dose intravenous Vancomycin after catheter replacement for suspected central line-associated bloodstream infection on resolution of infection in critically ill patients.
- Trial name
- VanCat (NCT04856878)
- Testing
- Vancomycin
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Parenteral Nutrition, Infection
The AOT (Acridine Orange and Taurolidine) Trial
Total parenteral (intravenous) nutrition in the home setting (Home TPN or HPN) is a life saving strategy in patients who suffer from severe intestinal failure.
- Conditions
- Parenteral Nutrition, Infection, Sepsis
- Trial name
- NCT00321165
- Testing
- taurolidine
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Radboud University Medical Center
Vascular Access Complication, Hemodialysis Access Failure
Optimizing Access Surgery In Senior Hemodialysis Patients
The number of elderly hemodialysis patients is growing. Vascular access complications are a major determinant of the quality of life and health care costs for these vulnerable patients.
- Conditions
- Vascular Access Complication, Hemodialysis Access Failure, Dialysis Access Malfunction, Arteriovenous Fistula
- Trial name
- OASIS (NCT05911451)
- Testing
- Arteriovenous fistula creation, Arteriovenous graft placement, Central venous catheter placement
- Where
- 20 sites in Netherlands
- Volunteers
- 166 people
- Sponsor
- Maastricht University Medical Center
Hemodialysis Catheter Blood Stream Infection, Central Line Infection
Randomised Controlled Trial of Needle Free Access Devices in Preventing Hemodialysis Blood Stream Infection
This study will be a randomised controlled trial examining whether a new type of needle free access device(TEGO) is associated with less episodes of infection of dialysis lines, when compared to the current gold standard.
- Conditions
- Hemodialysis Catheter Blood Stream Infection, Central Line Infection, Dialysis Line Thrombosis
- Trial name
- TEGO (NCT01082770)
- Testing
- TEGO, Standard
- Where
- Ireland
- Volunteers
- 106 people
- Sponsor
- Beaumont Hospital
Child, Only, Catheter Infection
Effect Of Open And Closed System Peripheral Catheters Used In Pediatric Services
The study was conducted as a randomized controlled experimental research to examine the effects of open and closed system peripheral catheters on the success of insertion, duration of stay, and development of complications in…
- Conditions
- Child, Only, Catheter Infection, Catheter Complications
- Trial name
- NCT06312215
- Testing
- Closed-system catheter
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Infection, Bacteremia
UGIST: Ultrasound Guided Internal Jugular Short-Term Central Venous Catheters Tunneling
The purpose of the study is to determine if tunneling standard short-term central lines for a short distance under the skin, with the assistance of ultrasound imaging, reduces the risk of central line infections for catheters…
- Trial name
- UGIST (NCT00639197)
- Testing
- To tunnel, Standard (not to tunnel)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Hamilton Health Sciences Corporation
Acute Infectious Diseases
Evaluation of Medical Device
A preliminary study was conducted from 01/26/2015 to 10/26/2015 on 605 patients admitted to MIA with an intravenous and/or a urinary catheter.
- Trial name
- NCT03329768
- Where
- France
- Volunteers
- 3,000 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
CRBSI - Catheter Related Bloodstream Infection
Investigational Study With the BD PosiFlush™ SafeScrub on NADs
This study is an investigational study to evaluate the safety and performance of the BD PosiFlush™ SafeScrub on needleless access devices.
- Trial name
- NCT06604026
- Testing
- BD PosiFlush™ SafeScrub, BD PosiFlush™
- Where
- 2 sites in Austria
- Volunteers
- 222 people
- Sponsor
- Becton, Dickinson and Company
Intensive Care Units, Neonatal, Misadventures to Patients During Surgical and Medical Care
SEPREVEN: a Stepped-wedge Randomised Controlled Trial
Adverse events are frequent in Neonatal Intensive Care Units' (NICU) patients and account for a high morbidity and mortality. Possible severe adverse events are central line associated bloodstream infections (CLABSI), ventilator…
- Conditions
- Intensive Care Units, Neonatal, Misadventures to Patients During Surgical and Medical Care, Catheter-related Bloodstream Infection (CRBSI) Nos, Quality of Healthcare
- Trial name
- SEPREVEN (NCT02598609)
- Testing
- Education program for NICU caregivers
- Where
- 12 sites in France
- Volunteers
- 8,000 people
- Sponsor
- Dr Caeymaex Laurence
Bacteremia
Hub Cleansing to Prevent Hub Infection
Central venous catheter infections are common preventable adverse events among hospital patients. Microbes may enter catheter hubs, also known as needleless connectors, and result in downstream contamination.
- Trial name
- HUC-PHIN (NCT01563406)
- Testing
- 15 second scrub, 5 second scrub, 3.15% chlorhexidine/70% isopropyl alcohol
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Rush University Medical Center
Chronic Diseases
Urinary Catheter Self-care Management
It is important for healthcare professionals to be sensitive to the needs of patients undergoing urinary catheterization. Patients and their relatives should be educated, guided and supported by nurses and other healthcare…
- Trial name
- NCT06179238
- Testing
- Education, without patient education
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Kastamonu University
Central Line Associated Blood Stream Infections (CLABSI)
Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults And Adolescent Participants Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)
This is a Phase 3, randomized, double-blind, controlled, adaptive, 2-arm, multicenter study to demonstrate the efficacy and safety of DefenCath in adult and adolescent participants receiving home Total Parenteral Nutrition (TPN)…
- Trial name
- NCT06822426
- Testing
- (taurolidine and heparin) catheter lock solution, Heparin
- Where
- 24 sites in United States, Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- CorMedix Therapeutics