Clinical trials: Catheter Infection
Hemodialysis Catheter Infection, Catheter Thrombosis
Neutrolin Versus Heparin for Locking Hemodialysis Catheters
Hemodialysis catheter related bacterial infections represent a major cause of mortality and morbidity in the hemodialysis population.
- Trial name
- NCT03425448
- Testing
- Heparin, Neutrolin
- Volunteers
- 192 people
- Sponsor
- King Abdullah International Medical Research Center
Sepsis
Effect of Taurolidin on Prevention of Bloodstream Infection
Home parenteral nutrition (HPN) is a validated technique for patients with various intestinal disease leading to chronic malabsorption or obstruction, whatever the aetiology.
- Trial name
- Nutrilock (NCT00545831)
- Testing
- Taurolidine, Physiologic Serum
- Where
- 7 sites in France
- Volunteers
- 39 people
- Sponsor
- University Hospital, Rouen
Cancer
Risk Factors for Thromboembolic and Infectious Complications Related to Percutaneous Central Venous Catheters in Cancer - Prospective Multicenter Study
The purpose of this study is to identify risk factors for thromboembolic and /or infectious complications in 3,000 patients with solid tumor and receiving a Percutaneous Central Venous Catheter (PCVC).
- Trial name
- ONCOCIP (NCT02025894)
- Where
- 27 sites in France
- Volunteers
- 3,032 people
- Sponsor
- Institut de Cancérologie de la Loire
Kidney Disease, Chronic, Peritoneal Dialysis Catheter-Associated Peritonitis
Targeted Education ApproaCH to Improve Peritoneal Dialysis Outcomes Trial
For many patients peritoneal dialysis (PD) is the preferred form of dialysis to treat kidney disease as it provides greater flexibility and the ability to dialyse at home.
- Conditions
- Kidney Disease, Chronic, Peritoneal Dialysis Catheter-Associated Peritonitis, Peritoneal Dialysis Catheter Exit Site Infection, Peritoneal Dialysis Catheter Tunnel Infection
- Trial name
- TEACH-PD (NCT03816111)
- Testing
- TEACH-PD Training Curriculum, Current standard PD training
- Where
- 48 sites in Australia, New Zealand
- Volunteers
- 1,462 people
- Sponsor
- The University of Queensland
Thrombosis, Infections
Complications and Risk Factors Related With Central Venous Catheters in Cancer Patients
The investigators aim to determine the complications and risk factors related with peripherally inserted central catheters (PICCs) and central venous catheters (CVCs) in cancer patients.
- Trial name
- CVCCP (NCT01661218)
- Where
- China
- Volunteers
- 3,500 people
- Sponsor
- Beijing Huanxing Cancer Hospital
Catheter-Associated Infections, Catheter-Related Infections
Safety and Effectiveness of Novel Nitroglycerin Based Catheter Lock Solution
The objective of this Phase I/II pilot study is to evaluate the safety and effectiveness of a non- antibiotic chelator based lock solution that contains nitroglycerin in combination with sodium citrate and ethanol (NiCE lock…
- Trial name
- NCT02577718
- Testing
- Nitroglycerin-citrate-ethanol (NiCE)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Novel Anti-Infective Technologies, LLC
Peritoneal Dialysis Catheter Exit Site Infection, Peritoneal Dialysis Catheter Tunnel Infection
Silver-Impregnated Dressings for Catheter Exit-Site and Tunnel Infections in Peritoneal Dialysis Patients
The goal of this clinical trial is to evaluate the feasibility and acceptability of using silver-impregnated dressings, compared to standard daily topical antibiotic exit-site dressings, for the management of catheter exit-site…
- Trial name
- NCT07641491
- Testing
- Silver-Impregnated Dressing, Standard Exit-Site Care With Topical Antibiotic Dressing
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- Singapore General Hospital
Catheter-related Bloodstream Infection (CRBSI) Nos
Clinical Trial Comparing Catheter Lock Solutions TaurolockTMHep 100 and Heparin 100 IE/ml.
The purpose of the investigation is to compare two catheter lock solutions (TaurolockTMHep100 and Heparin 100 IE/ml), on the occurence of catheter related blood stream infection, in patients with intestinal failure and a central…
- Trial name
- NCT01948245
- Testing
- TaurolockTMHep100, Heparin 100 IE/ml
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- Palle Bekker Jeppesen
Catheterization, Infection
Trial on the Efficacy of Tegaderm Chlorhexidine Gluconate (CHG) in Reducing Catheter Related Bloodstream Infections
TegaCHG is a multicentric randomized study aimed at evaluating the possibility that the use of TegaDerm CHG dressing may reduce the incidence of catheter related blood stream infections (CRBSI).
- Trial name
- TegaCHG (NCT01142934)
- Testing
- Transparent adhesive dressing with an integrated gel pad containing 2% w/w chlorhexidine gluconate (CHG) (TegaDerm CHG)
- Where
- 8 sites in Italy
- Volunteers
- 1,200 people
- Sponsor
- Catholic University of the Sacred Heart
Complications; Catheter, Urinary Infection or Inflammation
BIP Foley in Prevention of CAUTI at Rehab Station
This is a prospective, cross-over, randomized, controlled, partly blinded study evaluating safety and performance of noble metal alloy urinary Catheters (BIP Foley, Bactiguard AB) of both latex and silicone.
- Trial name
- CDOC (NCT02808000)
- Testing
- BIP Foley (latex) or BIP Foley -silicone, Standard catheter
- Where
- Sweden
- Volunteers
- 14 people
- Sponsor
- Bactiguard AB
Biofilms, Arterial Catheterization, Peripheral
Structural and Microbiological Characterization of Arterial Catheter Biofilm in ICU's Patients Using Optical Coherence Tomography
29.3% of bacteremias in intensive care units (ICU) are linked to vascular devices, including 7.7% to arterial catheters, with an influence on both morbility and mortality.
- Conditions
- Biofilms, Arterial Catheterization, Peripheral, Bacteremia, Tomography, Optical Coherence
- Trial name
- OCT-BIO-KTA (NCT06838598)
- Testing
- OCT-BIO-KTA cohort
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier William Morey - Chalon sur Saône
Bacteriaemia, Catheter Related Bloodstream Infection
Rate of Catheter Colonization and Risk of Bloodstream Infection During Use of Two Different Central Venous Catheters (CVC)
The use of these catheters is associated with infectious complications that are an important iatrogenic source of morbidity and mortality.
- Trial name
- NCT00555282
- Testing
- central venous catheter
- Where
- 2 sites in Czechia
- Volunteers
- 680 people
- Sponsor
- B. Braun Melsungen AG
Catheter-related Bloodstream Infection, Preterm
Lock sOlutiOnS for Epicutaneo-caval Catheters in Neonates: a "LOOSEN" Pilot Study
Epicutaneo-caval catheters (ECCs) are widely used in neonatal intensive care units (NICUs). They are small catheters inserted via superficial veins of the limbs or scalp using direct vein visualization The pathogenic…
- Conditions
- Catheter-related Bloodstream Infection, Preterm, Catheter Infection, Catheter Complications
- Trial name
- LOOSEN (NCT05729321)
- Testing
- neutrox
- Where
- 2 sites in Italy
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Staphylococcal Infections
Vancomycin Study: Treatment of Catheter Related Bloodstream Infection Caused by Coagulase Negative Staphylococcus
Patients admitted into the Intensive Care Unit (ICU) have an intravenous (IV) catheter (small plastic tube) placed in their vein.
- Trial name
- NCT00175370
- Testing
- Vancomycin
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Catheter-Associated Urinary Tract Infection
Vitamin C Effectiveness in Preventing Urinary Tract Infections After Gynecological Surgeries
Double-blind placebo-controlled randomized trial aiming to assess the role of Vitamin C supplementation in the prevention of catheter-associated urinary tract infections in women undergoing elective gynecological surgeries.
- Trial name
- NCT05913180
- Testing
- Ascorbic Acid 1000 MG
- Where
- Russia
- Volunteers
- 180 people
- Sponsor
- American University of Beirut Medical Center
Cardiovascular Infections, Peripheral Vascular Disease
Placement of Peripherally Inserted Central Venous Catheters (PICC) in Children Guided by Ultrasound
Aimed to compare the success in the peripheral intravenous puncture (PIP), progression and placement of PICC in children, according to the use of Doppler vascular ultrasound (DVUS) or traditional method; to identify the influence…
- Trial name
- NCT01279642
- Testing
- ultrasound, traditional puncture
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Catheter-related Bloodstream Infection
Expanded Access Program for Patients at Risk for Catheter-related Infections Who Are Not Eligible for DefenCath® Clinical Trials
The EAP for DefenCath is designed to provide access to a broader population of adult and pediatric patients using catheters for various serious medical conditions.
- Trial name
- NCT06707480
- Testing
- Taurolidine and Heparin
- Sponsor
- CorMedix Therapeutics
Catheter-related Infections
Mino-Lok Therapy (MLT) for the Treatment of CRBSI/CLABSI
This is a Phase 3, multi-center, randomized, open-label, assess-blind study to determine the efficacy and safety of MLT, a novel antibiotic lock therapy that combines minocycline with edetate disodium in 25% ethanol solution as…
- Trial name
- NCT02901717
- Testing
- Mino-Lok, Antibiotic lock
- Where
- 22 sites in United States, Puerto Rico
- Volunteers
- 144 people
- Sponsor
- Leonard-Meron Biosciences, Inc.
Mechanical Ventilation, Pneumonia
Removal of Endotracheal Tube Secretions Comprehensively Until Extubation
The purpose of this study is to measure secretion accumulation within endotracheal tubes of mechanically ventilated patients and test the efficacy, safety and clinical impact of removing the secretions using novel airway…
- Trial name
- RESCUE (NCT00663637)
- Testing
- CAM (Complete Airway Management) Catheters
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- O. M. Neotech, Inc.
Bacterial Pneumonia
Assessment of the Diagnostic Capacity of the Mini-broncho Alveolar Lavage Performed Through a Suction Catheter
The aim of this study is to develop a safe and effective technique to take sample for lower respiratory tract cultures easy to perform in conditions of acute respiratory failure and spontaneous ventilation for patients admitted…
- Trial name
- Mini-LBA (NCT00763620)
- Testing
- catheter for mini bronchoalveolar lavage
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris