Clinical trials: Catheter-Associated Infection
Stroke, Catheter Associated Urinary Tract Infection
Pilot Study of Avoidance of Bladder Catheters in Stroke Patients to Avoid Urinary Tract Infections
The purpose of this study is to determine whether bladder catheterization can be safely avoided in patients admitted to the hospital with stroke using a nursing protocol, and whether this decreases the incidence of urinary tract…
- Trial name
- NCT01275261
- Testing
- Nursing protocol to avoid Foley catheter placement
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of California, San Francisco
Vascular Access Complication, Central Line Complication
Novel Strategy to Encourage Early Removal of Central Venous Catheters
The goal of this study is to determine if early placement of a midline catheter in patients with a central venous catheter (CVC) will decrease the number of days the CVC is in place.
- Conditions
- Vascular Access Complication, Central Line Complication, Central Line-Associated Infection, Superficial Vein Thrombosis
- Trial name
- NCT04136561
- Testing
- Midline catheter
- Where
- United States
- Sponsor
- Corewell Health East
Catheter-Related Infections
Efficacy and Safety of Ethanol Lock Therapy for the Prevention of Central Line-associated Bloodstream Infections
Patients on long-term parenteral nutrition (PN) are at high risk for central line-associated bloodstream infections (CLABSI). This study evaluates the efficacy and safety of ethanol lock therapy for CLABSI prophylaxis in adult…
- Trial name
- NCT02890875
- Testing
- Ethanol lock, Heparin lock
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Stanford University
Chlorhexidine
Dressing Impregnated With Chlorhexidine and Vancomycin for the Prophylaxis of Central Venous Catheter-related Infections - a Randomized Trial
You are being invited as a volunteer to participate in the study "Dressing impregnated with chlorhexidine and vancomycin for the prophylaxis of central venous catheter-related infections." The objective is to evaluate the…
- Trial name
- Dressing RCT (NCT07001527)
- Testing
- Chlorhexidine
- Where
- Brazil
- Volunteers
- 516 people
- Sponsor
- Hospital Universitario Evangelico de Curitiba
Critical Illness, Burns
Effect of Active Drain Line Clearance on Catheter-Associated Bacteriuria
Catheter-associated urinary tract infections (CAUTI) are the most common nosocomial infections in critically ill patients and are responsible for high morbidity rates, increased hospital stays and associated costs.
- Conditions
- Critical Illness, Burns, Surgery, Urinary Tract Infections
- Trial name
- CAB (NCT03816384)
- Testing
- Standard of Care, DLC Group, DLCS Group
- Sponsor
- Potrero Medical
Urinary Infections
Prevention of Catheter Associated Lower Urinary Infections Using the Oxys Indwelling Catheter
The safety and efficacy of a urinary catheter designed to prevent catheter associated urinary infections is studied.
- Trial name
- NCT02658903
- Testing
- Oxys Catheter, Covidien Mona-Therm Foley catheter
- Where
- Switzerland
- Volunteers
- 54 people
- Sponsor
- Oxys Medical AG
Intensive Care
Novel Device for Reducing Catheter-Related Infections
This study is a pilot study of the safety, tolerability and efficacy of an investigational central venous catheter device used in conjunction with a standard central venous catheter.
- Trial name
- NCT00878683
- Testing
- silicone catheter boot
- Sponsor
- University of Kansas
Catheter Complications
Use of Tetrasodium EDTA Catheter Lock Solution for Patients on HTPN
Parenteral nutrition (PN) is a lifesaving therapy in patients with chronic intestinal failure. PN is administered via a central venous catheter (CVC), and patients are dependent on this line for ongoing nutrition.
- Trial name
- NCT04067245
- Testing
- Tetrasodium EDTA catheter lock solution
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
Hemodialysis Catheter-Associated Bacteremia, Hemodialysis Complication
Ethanol Lock and Risk of Catheter Related Blood Stream Infection in Patients With Haemodialysis Catheter
The aim of this study is to examine the effect of ethanol (70%) as lock-solution after hemodialysis on: The frequency of dialysis catheter-related bacteremia among patients under observation of potential complications Other…
- Trial name
- NCT05953675
- Testing
- Ethanol 70%, Isotonic saline with heparin
- Where
- Denmark
- Volunteers
- 280 people
- Sponsor
- Zealand University Hospital
Recurrent UTIs, Catheter-Related Infections
Novel Probiotic Treatment for Prevention of Recurrent UTIs in Children
Background: Urinary tract infections (UTIs) are a common and costly cause of doctor visits for children. Frequent UTIs trigger kidney damage that leads to serious diseases like high blood pressure, pregnancy complications, and…
- Trial name
- Nissle 1917 (NCT01696227)
- Testing
- Nissle 1917
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Urinary Tract Infections
Probiotic Bladder Instillation for Prevention of Catheter Associated UTIs in Chronically Catheterized Patients
The proposed study is a randomized, placebo-controlled clinical trial to test the efficacy of an oral Lactobacillus product dissolved in sterile saline and instilled into the urinary bladder in an attempt to colonize the urinary…
- Trial name
- NCT04077749
- Testing
- Femdophilus probiotic, Normal Saline
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lahey Clinic
Catheterization
Study of Chlorhexidine as the Hub Antiseptic to Prevent Catheter Related Infections in Newborn Infants
The purpose of this study is to prevent catheter-related infections in newborn infants admitted to the Neonatal Intensive Care Unit (NICU).
- Trial name
- NCT00516360
- Testing
- 3.15% chlorhexidine as daily antiseptic on needleless access port
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Catheter-Related Infections
Analysis of Microbial Biofilms in Peripheral Venous Catheters and Their Implication in Infectious Risk
Peripheral venous catheters (PVCs) are the most commonly used intravascular medical devices in healthcare establishments. Although essential in patient care, PVCs represent a significant risk factor for nosocomial infections, as…
- Trial name
- KTBIO (NCT07258862)
- Testing
- Inflammatory catheters: catheter removed because of infection at insertion site, Non-inflammatory catheters: catheter removed because it is no longer relevant to keep it in place
- Where
- 2 sites in France
- Volunteers
- 250 people
- Sponsor
- Hôpital NOVO
Intraventricular Hemorrhage
ACTIVE Study - Use of ACTIVE Fluid Exchange to Treat Intraventricular Hemorrhage
Randomised controlled trial evaluating active irrigation using IRRAflow device in patients with intraventricular hemorrhages (IVH).
- Trial name
- NCT05204849
- Testing
- IRRAflow, Standard ventriculostomy
- Where
- Denmark
- Volunteers
- 58 people
- Sponsor
- University of Aarhus
Hematological Malignancies, Bacteremia
Concentrated Citrate Locking to Reduce the Incidence of CVC-related Complications in Hematological Patients
Patients with a hematological malignancy who are undergoing intensive chemotherapy need a central venous catheter (CVC)during their treatment. CVCs are locked with heparin when they are not used.
- Conditions
- Hematological Malignancies, Bacteremia, Thrombosis
- Trial name
- NCT01820962
- Testing
- heparin, concentrated citrate
- Where
- 2 sites in Netherlands
- Volunteers
- 212 people
- Sponsor
- Maastricht University Medical Center
Catheter-Associated Urinary Tract Infection, Catheter Related Complication
Comparative Study Between Foley and T-Control® Catheter in Patients With Long-term Catheterization
This is a comparative, randomized, controlled pilot study. The main objective of this study is to evaluate the efficacy, comfort, and patient experience in people with long-term bladder catheterization with T-Control® versus…
- Conditions
- Catheter-Associated Urinary Tract Infection, Catheter Related Complication, Quality of Life
- Trial name
- NCT05860231
- Testing
- Foley catheter, T-Control catheter
- Where
- 2 sites in Spain
- Volunteers
- 50 people
- Sponsor
- Rethink Medical SL
Healthcare Associated Infection, Critically Ill
Dynamic Full-Field Optical Coherence Tomography for Structural and Microbiological Characterization of Central Venous Catheter-deposited Biofilm in Critically Ill Patients
29.3% of bacteremias in intensive care units (ICU) are linked to vascular devices, with a significant proportion related to central venous catheters, and an influence on both morbility and mortality.
- Conditions
- Healthcare Associated Infection, Critically Ill, Central Venous Catheter Associated Bloodstream Infection
- Trial name
- OCT-BIO-CVC (NCT06216080)
- Testing
- D-FF-OCT analysis of CVC
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier William Morey - Chalon sur Saône
Ventilator Acquired Pneumonia, Catheter Related Blood Stream Infections
Ontario ICU Clinical Best Practices Demonstration Project
The pragmatic issue at hand how to get physicians and nurses to use best practices… and how to measure consequences of their implementation.
- Conditions
- Ventilator Acquired Pneumonia, Catheter Related Blood Stream Infections, Pressure Ulcer Prophylaxis, DVT Prophylaxis
- Trial name
- NCT00332982
- Testing
- Focused knowledge translation strategies
- Where
- Canada
- Sponsor
- Sunnybrook Health Sciences Centre
Artificial Intelligence, Central Venous Catheter Associated Bloodstream Infection
Artificial Intelligence With Determination of Central Venous Catheter Line Associated Infection Risk
The goal of this methodological, retrospective and prospective study is to; it is a tool to develop a risk estimator tool to detect risk gaps in individuals using artificial intelligence technology that is dangerous for those…
- Trial name
- NCT05914571
- Volunteers
- 2,000 people
- Sponsor
- Saglik Bilimleri Universitesi
Catheter Blockage, Catheter-Related Infections
Comparison of Effectiveness and Complications of Catheter Lock Solutions in Non-tunneled Hemodialysis Catheters
In our study, investigators will investigate the effectiveness and complications of two catheter lock solutions one of which is the standard heparin routinely used in comparison to Sodium bicarbonate.
- Conditions
- Catheter Blockage, Catheter-Related Infections, Dialysis Catheter; Thrombosis, Catheter Infection
- Trial name
- NCT04772209
- Testing
- Sodium bicarbonate, Heparin
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 441 people
- Sponsor
- Zonguldak Ataturk State Hospital