Clinical trials: Catheter-Related Infections
Critical Illness
The Effects of Anti-infective Central Venous Catheter on Catheter-related Infection in Critically Patients
The purpose of this study is to investigate the effect of anti-infective central venous catheter(Certofix®Protect) on reducing catheter-related bloodstream infection in critically ill patients in China, and the relationship…
- Trial name
- NCT02645682
- Testing
- anti-infection CVC, normal CVC
- Where
- 2 sites in China
- Volunteers
- 1,818 people
- Sponsor
- West China Hospital
Central Venous Catheter Exit Site Infection, Catheter-Related Infections
Comparing CHG I.V. Securement Dressing With Transparent Dressing for Evaluation of Antimicrobial Efficacy
This is a single-center, prospective, randomized controlled clinical trial designed to compare the antimicrobial efficacy of Tegaderm CHG I.V.
- Trial name
- NCT04906512
- Testing
- 3M™ Tegaderm™ CHG I.V. Securement Dressing, 3M™ Tegaderm™ Transparent Film Dressing 1626W
- Where
- China
- Volunteers
- 123 people
- Sponsor
- Solventum US LLC
Epidural Catheter-Related Infection, Hospital-Acquired Infection
Epidural Catheter and Port-Related Infections in Pain Clinic Patients
This retrospective observational study aims to evaluate the incidence and risk factors of infection associated with epidural catheter and port applications performed in the Pain Clinic of Mersin University Faculty of Medicine.
- Conditions
- Epidural Catheter-Related Infection, Hospital-Acquired Infection, Procedural Complication
- Trial name
- NCT07242560
- Where
- Turkey (Türkiye)
- Volunteers
- 351 people
- Sponsor
- Mesut Bakır
Catheter-related Bloodstream Infection
High-Flow Needleless Valve and DualCap Disinfection Devices Associate With Catheter-related Bloodstream Infection
The purpose of this study is to investigate whether the usage of High-Flow Needleless Valve and DualCap Disinfection Devices would reduce the incidence of catheter-related bloodstream infection in hemodialysis patients.
- Trial name
- NCT02990923
- Testing
- High-Flow Needleless Valve, DualCap Disinfection Devices
- Volunteers
- 102 people
- Sponsor
- Peking University First Hospital
Catheter-related Bloodstream Infection
Comparison of Early Phase Infections Risk Between Midline and Piccline Caheters: MIDLINE AND PICCLINE CATHETERS
A long-term venous access is frequently required in patient management. Currently, it is ensured by using the long peripheral intravenous catheters (Midline) or peripheral inserted central catheters (PICC line).
- Trial name
- PICCORMID (NCT05264402)
- Where
- France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Chronic Renal Failure, Haemodialysis, Haemodiafiltration, Haemofiltration
Catheter Dysfunction Rate in Patients Undergoing Kidney Replacement Therapy. Evaluation of the Safety and Efficacy of Anti-reflux Valves Without Heparin Lock Solution
Catheter dysfunction and infections are the most common complications observed among patients with dialysis catheters for long-term dialysis ( CDLD ) .
- Conditions
- Chronic Renal Failure, Haemodialysis, Haemodiafiltration, Haemofiltration, Kidney Replacement Therapy, Catheter Infection, Catheter Dysfunction, Catheter Related Bloodstream Infections
- Trial name
- DUKE (NCT06259266)
- Testing
- Anti-reflux valve for dialysis catheter
- Where
- France
- Sponsor
- University Hospital, Clermont-Ferrand
Catheter-Related Infections
Efficacy and Safety of Ethanol Lock Therapy for the Prevention of Central Line-associated Bloodstream Infections
Patients on long-term parenteral nutrition (PN) are at high risk for central line-associated bloodstream infections (CLABSI). This study evaluates the efficacy and safety of ethanol lock therapy for CLABSI prophylaxis in adult…
- Trial name
- NCT02890875
- Testing
- Ethanol lock, Heparin lock
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Stanford University
Acute Renal Failure, Infection
Efficacy and Safety of Ethanol Lock Solution in Prevention of Catheter Related Bloodstream Infection for Patients Suffering Acute Renal Failure, and Hospitalized in Intensive Care Unit. A Multi-Center, Randomized, Versus Placebo, Double Blinded Clinical Trial
The primary objective of the study is to demonstrate the efficacy of 60% ethanol lock solution in preventing major catheter related infections in critically ill patients.
- Trial name
- ELVIS (NCT00875069)
- Testing
- Ethanol
- Where
- France
- Volunteers
- 1,460 people
- Sponsor
- University Hospital, Clermont-Ferrand
Chlorhexidine
Dressing Impregnated With Chlorhexidine and Vancomycin for the Prophylaxis of Central Venous Catheter-related Infections - a Randomized Trial
You are being invited as a volunteer to participate in the study "Dressing impregnated with chlorhexidine and vancomycin for the prophylaxis of central venous catheter-related infections." The objective is to evaluate the…
- Trial name
- Dressing RCT (NCT07001527)
- Testing
- Chlorhexidine
- Where
- Brazil
- Volunteers
- 516 people
- Sponsor
- Hospital Universitario Evangelico de Curitiba
Intensive Care
Novel Device for Reducing Catheter-Related Infections
This study is a pilot study of the safety, tolerability and efficacy of an investigational central venous catheter device used in conjunction with a standard central venous catheter.
- Trial name
- NCT00878683
- Testing
- silicone catheter boot
- Sponsor
- University of Kansas
Catheter Complications
Use of Tetrasodium EDTA Catheter Lock Solution for Patients on HTPN
Parenteral nutrition (PN) is a lifesaving therapy in patients with chronic intestinal failure. PN is administered via a central venous catheter (CVC), and patients are dependent on this line for ongoing nutrition.
- Trial name
- NCT04067245
- Testing
- Tetrasodium EDTA catheter lock solution
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
Hemodialysis Catheter-Associated Bacteremia, Hemodialysis Complication
Ethanol Lock and Risk of Catheter Related Blood Stream Infection in Patients With Haemodialysis Catheter
The aim of this study is to examine the effect of ethanol (70%) as lock-solution after hemodialysis on: The frequency of dialysis catheter-related bacteremia among patients under observation of potential complications Other…
- Trial name
- NCT05953675
- Testing
- Ethanol 70%, Isotonic saline with heparin
- Where
- Denmark
- Volunteers
- 280 people
- Sponsor
- Zealand University Hospital
Recurrent UTIs, Catheter-Related Infections
Novel Probiotic Treatment for Prevention of Recurrent UTIs in Children
Background: Urinary tract infections (UTIs) are a common and costly cause of doctor visits for children. Frequent UTIs trigger kidney damage that leads to serious diseases like high blood pressure, pregnancy complications, and…
- Trial name
- Nissle 1917 (NCT01696227)
- Testing
- Nissle 1917
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Bacterial Infections
Safety and Efficacy Study of Angiotech Central Venous Catheter to Prevent Bacterial Catheter Colonization
The main purpose of this study is to determine if the Angiotech central venous catheter (CVC) is equal in effectiveness to a CVC coated with chlorhexidine and silver sulfadiazine in preventing bacterial catheter colonization.
- Trial name
- NCT00288418
- Testing
- Central Venous Catheter
- Where
- 21 sites in United States
- Volunteers
- 960 people
- Sponsor
- Angiotech Pharmaceuticals
Children in the Pediatric Intensive Care Unit or General Pediatric Care Unit Requiring a Central Venous Catheter
Study of the Use of Coated Venous Catheters in the Critically Ill Child
This study should help determine to determine whether or not the use of an antibiotic coated catheter will significantly reduce the number of central line related bloodstream infections in children requiring a CVC.
- Trial name
- NCT00202813
- Testing
- Cook Spectrum Pediatric Central Venous Catheter Anti-microbial Impregnated Polyurethane and Arrow Pediatric Central Venous Catheter
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Corewell Health West
Catheterization
Study of Chlorhexidine as the Hub Antiseptic to Prevent Catheter Related Infections in Newborn Infants
The purpose of this study is to prevent catheter-related infections in newborn infants admitted to the Neonatal Intensive Care Unit (NICU).
- Trial name
- NCT00516360
- Testing
- 3.15% chlorhexidine as daily antiseptic on needleless access port
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Catheter-Related Infections
Analysis of Microbial Biofilms in Peripheral Venous Catheters and Their Implication in Infectious Risk
Peripheral venous catheters (PVCs) are the most commonly used intravascular medical devices in healthcare establishments. Although essential in patient care, PVCs represent a significant risk factor for nosocomial infections, as…
- Trial name
- KTBIO (NCT07258862)
- Testing
- Inflammatory catheters: catheter removed because of infection at insertion site, Non-inflammatory catheters: catheter removed because it is no longer relevant to keep it in place
- Where
- 2 sites in France
- Volunteers
- 250 people
- Sponsor
- Hôpital NOVO
Intraventricular Hemorrhage
ACTIVE Study - Use of ACTIVE Fluid Exchange to Treat Intraventricular Hemorrhage
Randomised controlled trial evaluating active irrigation using IRRAflow device in patients with intraventricular hemorrhages (IVH).
- Trial name
- NCT05204849
- Testing
- IRRAflow, Standard ventriculostomy
- Where
- Denmark
- Volunteers
- 58 people
- Sponsor
- University of Aarhus
Hematological Malignancies, Bacteremia
Concentrated Citrate Locking to Reduce the Incidence of CVC-related Complications in Hematological Patients
Patients with a hematological malignancy who are undergoing intensive chemotherapy need a central venous catheter (CVC)during their treatment. CVCs are locked with heparin when they are not used.
- Conditions
- Hematological Malignancies, Bacteremia, Thrombosis
- Trial name
- NCT01820962
- Testing
- heparin, concentrated citrate
- Where
- 2 sites in Netherlands
- Volunteers
- 212 people
- Sponsor
- Maastricht University Medical Center
Catheter-Associated Urinary Tract Infection, Catheter Related Complication
Comparative Study Between Foley and T-Control® Catheter in Patients With Long-term Catheterization
This is a comparative, randomized, controlled pilot study. The main objective of this study is to evaluate the efficacy, comfort, and patient experience in people with long-term bladder catheterization with T-Control® versus…
- Conditions
- Catheter-Associated Urinary Tract Infection, Catheter Related Complication, Quality of Life
- Trial name
- NCT05860231
- Testing
- Foley catheter, T-Control catheter
- Where
- 2 sites in Spain
- Volunteers
- 50 people
- Sponsor
- Rethink Medical SL