Clinical trials: Catheter-Related Infections
Catheter-Related Infections, Central Venous Catheters
Advanced Dressings for CVC Infection Prevention in PICU
Randomised, single-blind clinical trial comparing chlorhexidine gluconate-impregnated transparent dressings versus conventional transparent dressings in the prevention of central venous catheter-related bloodstream infections…
- Conditions
- Catheter-Related Infections, Central Venous Catheters, Bloodstream Infection, Pediatric Intensive Care Units
- Trial name
- NCT07175116
- Testing
- 3M™ Tegaderm™ Antimicrobial Transparent Dressing (chlorhexidine gluconate-impregnated), Conventional transparent polyurethane dressing
- Where
- Spain
- Volunteers
- 250 people
- Sponsor
- University of Seville
Intestinal Failure, CRBSI - Catheter Related Bloodstream Infection
8.4% Sodium Bicarbonate Locks in Intestinal Failure
We plan to include children with intestinal failure, a condition where the gut is not functioning properly, leading these children to need central venous catheters (line that goes through the skin into the blood stream) for…
- Trial name
- NCT05813535
- Testing
- Sodium bicarb lock
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Riad Rahhal
Kidney Failure, Chronic, Catheter-Related Infections
Study Assessing Safety & Effectiveness of a Catheter Lock Solution in Dialysis Patients to Prevent Bloodstream Infection
The purpose of this study is determine safety and effectiveness of Neutrolin, a catheter lock solution, for prevention of central venous catheter associated bloodstream infection in hemodialysis patients.
- Trial name
- NCT02651428
- Testing
- Neutrolin, Heparin
- Where
- 5 sites in United States
- Volunteers
- 806 people
- Sponsor
- CorMedix Therapeutics
IV Catheter-Related Infection or Complication, Vascular Access Complication
Blood Sampling Functionality of Extended Dwell Catheters
The purpose of this study is to compare upper arm versus forearm Extended Dwell Catheter (EDC) placement for blood sampling functionality.
- Conditions
- IV Catheter-Related Infection or Complication, Vascular Access Complication, Peripheral Venous Access
- Trial name
- NCT04409418
- Testing
- Extended dwell catheters
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Corewell Health East
Central Venous Catheter Exit Site Infection, Catheter-Related Infections
Comparing CHG I.V. Securement Dressing With Transparent Dressing for Evaluation of Antimicrobial Efficacy
This is a single-center, prospective, randomized controlled clinical trial designed to compare the antimicrobial efficacy of Tegaderm CHG I.V.
- Trial name
- NCT04906512
- Testing
- 3M™ Tegaderm™ CHG I.V. Securement Dressing, 3M™ Tegaderm™ Transparent Film Dressing 1626W
- Where
- China
- Volunteers
- 123 people
- Sponsor
- Solventum US LLC
Kidney Failure, Chronic, Hemodialysis Complication
The Pristine Post-Market Study
This is a prospective, multi-center, single-arm study designed to assess the safety and performance of the Pristine™ Long-Term Hemodialysis Catheter.
- Conditions
- Kidney Failure, Chronic, Hemodialysis Complication, Hemodialysis Catheter Infection, Hemodialysis Access Failure
- Trial name
- NCT05228132
- Testing
- Pristine™ Long-Term Hemodialysis Catheter
- Where
- 6 sites in United States
- Volunteers
- 142 people
- Sponsor
- C. R. Bard
IV Catheter-Related Infection or Complication
A Clinical Trial Using a New Medical Device to Evaluate Its Impact on IV Care and Clinical Complications
A clinical trial comparing two groups of patients that are randomized into one group having SafeBreak Vascular attached to their peripheral IV lines and a second control group that receives the current standard of care (no…
- Trial name
- DIPPER (NCT04469218)
- Testing
- SafeBreak Vascular
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Lineus Medical
Catheter Related Infections
Quality Control: A Prospective Analysis of EVD Effectiveness
The purpose and/or hypothesis: To decrease the amount of external ventricular drain (EVD) related catheter infections by comparing the efficacy of Oklahoma University Medicine standard EVD catheters, both impregnated and…
- Trial name
- NCT02484287
- Testing
- The Integra External Drainage Catheter., The Ventriclear EVD Antibiotic Catheter, The Codman Bactiseal EVD Catheter Set
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Oklahoma
Catheter-related Bloodstream Infection
SQ53 Disinfectant Wipes for Prevention of CRBSI
SQ53 is a novel antimicrobial, sporicidal solution that is based on a platform of quaternary ammonium chloride compounds. It has been tested against a wide range of bacteria, viruses, spores and fungal pathogens.
- Trial name
- NCT04822467
- Testing
- SQ53 Wipe, Ethanol Wipe
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- The Cleveland Clinic
Urinary Tract Infections, Catheter-Related Infections
Short-course Methenamine Hippurate for Prevention of Post-operative UTI
The investigators will determine the efficacy of an innovative short regimen of methenamine hippurate on prevention of post-operative UTI in patients requiring short-term catheterization after pelvic reconstructive surgery…
- Trial name
- NO-UTI (NCT02358993)
- Testing
- methenamine hippurate, Ciprofloxacin
- Where
- 4 sites in United States
- Volunteers
- 201 people
- Sponsor
- University of Pennsylvania
Childhood Cancer, Central Venous Catheters
Identification and Treatment of Clinically Silent Catheter-Related Deep Vein Thrombosis in Children With Cancer
The primary hypothesis of this study is that occult catheter-related DVT in children with cancer is common and directly contributes to development of serious catheter complications, specifically bacteremia/fungemia and/or…
- Conditions
- Childhood Cancer, Central Venous Catheters, Deep Vein Thrombosis, Catheter-related Infection
- Trial name
- DVT (NCT00633061)
- Testing
- Enoxaparin
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- University of Texas Southwestern Medical Center
Urinary Tract Infections, Catheter Infection
Reducing Urinary Tract Infection Rates Using a Controlled Aseptic Protocol for Catheter Insertion
Urinary Tract Infection (UTI) complications following catheter use in surgical patients remains high. Using an aseptic protocol has been shown to drastically reduce UTI incidence by 50%.
- Conditions
- Urinary Tract Infections, Catheter Infection, Catheter-Related Infections
- Trial name
- NCT03101371
- Testing
- Catheter insertion with Povidone Iodine, Standard of care catheter insertion
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of Colorado, Denver
Catheter; Infection (Indwelling Catheter), Catheter Infection
Betadine Bladder Irrigations vs. Standard of Care Prior to Indwelling Catheter Removal
Over the last decade, there has been great emphasis on reducing the incidence of hospital-acquired infections, including catheter-associated UTI (CAUTI).
- Conditions
- Catheter; Infection (Indwelling Catheter), Catheter Infection, Catheter-Related Infections, Catheter Bacteraemia
- Trial name
- NCT03447639
- Testing
- Povidone-iodine irrigation
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Corewell Health East
Urinary Retention, Urinary Tract Infections
Prevention of Post-operative Urinary Retention
The purpose of this study is to determine if tamsulosin ("FLOMAX") is effective in preventing post-operative urinary retention following abdominal surgery.
- Trial name
- POUR (NCT02486653)
- Testing
- Tamsulosin
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- University of Wisconsin, Madison
Infection Associated With Catheter, Urinary Tract Infection
Silver-impregnated Suprapubic Catheters (SPC) in Urogynecology
The purpose of this study is to compare urinary tract infection rates among women undergoing urogynecological procedures with a silver-alloy suprapubic catheter compared to the standard suprapubic catheter.
- Trial name
- NCT01359046
- Testing
- silver SPC, standard SPC
- Where
- United States
- Volunteers
- 288 people
- Sponsor
- Mayo Clinic
Cross Infection, Pneumonia, Ventilator-associated
Trial of 2% Chlorhexidine Bathing on Nosocomial Infections in the Surgical Intensive Care Unit
This prospective, randomized, controlled trial will compare the incidence of nosocomial infections (composite of primary bloodstream infections, catheter-associated urinary tract infections, ventilator-associated pneumonia, and…
- Conditions
- Cross Infection, Pneumonia, Ventilator-associated, Catheter-related Infections, Infection Due to Indwelling Urinary Catheter
- Trial name
- NCT01640925
- Testing
- Chlorhexidine gluconate, Standard bathing
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Joshua Swan
Catheter-related Bloodstream Infection (CRBSI) Nos, Bloodstream Infection Due to Central Venous Catheter
Prophylactic Ethanol Lock Therapy (ELT) in Patients on Home Parenteral Nutrition
This study is being implemented to identify the role of prophylactic use of ethanol lock in adult patients on home parenteral nutrition (HPN).
- Conditions
- Catheter-related Bloodstream Infection (CRBSI) Nos, Bloodstream Infection Due to Central Venous Catheter, Bloodstream Infection Due to Hickman Catheter
- Trial name
- ELT (NCT02227329)
- Testing
- Ethanol, Heparin Lock, Normal Saline
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Mayo Clinic
Catheter-Associated Infections, Catheter-Related Infections
Safety and Effectiveness of Novel Nitroglycerin Based Catheter Lock Solution
The objective of this Phase I/II pilot study is to evaluate the safety and effectiveness of a non- antibiotic chelator based lock solution that contains nitroglycerin in combination with sodium citrate and ethanol (NiCE lock…
- Trial name
- NCT02577718
- Testing
- Nitroglycerin-citrate-ethanol (NiCE)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Novel Anti-Infective Technologies, LLC
Catheter-Related Infections
Pediatric Ethanol Lock Therapy Study.
This study is a double-blind crossover design to compare prophylaxis with ethanol lock therapy versus placebo lock therapy (heparin).
- Trial name
- NCT00948441
- Testing
- 25% ethanol, heparin lock
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Pittsburgh
Catheter-related Bloodstream Infection
Reducing Catheter-Related Bloodstream Infections in the ICU With a Chlorhexidine-Impregnated Sponge (BIOPATCH)
We proposed to perform a prospective randomized controlled trial to study the effect of the use of a commercially-available chlorhexidine-impregnated sponge (Biopatch) as part of central venous catheter care on catheter-related…
- Trial name
- NCT00548132
- Testing
- Chlorhexidine-impregnated foam dressing
- Where
- United States
- Volunteers
- 1,088 people
- Sponsor
- Washington University School of Medicine