Clinical trials: Cellulitis, active
Methicillin Resistant Staphylococcus Aureus, Osteomyelitis Acute
Trimethoprim-sulfamethoxazole vs. Clindamycin for the Treatment of Children With Invasive MRSA Infections
The goal of this clinical trial is to learn if trimethoprim-sulfamethoxazole (TMP-SMX) works to treat invasive infections due to methicillin-resistant Staphylococcus aureus (MRSA) in children.
- Conditions
- Methicillin Resistant Staphylococcus Aureus, Osteomyelitis Acute, Septic Arthritis, Orbital Cellulitis
- Trial name
- NCT06982105
- Testing
- Trimethoprim Sulfamethoxazole
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Indiana University
Atopic Dermatitis
Retention of Vernix Caseosa in Newborns for Primary Prevention of Atopic Dermatitis
Atopic dermatitis (AD), also known as eczema, is a common chronic inflammatory skin disease that usually begins in infancy and causes significant itching, discomfort, and sleep disturbance.
- Trial name
- PROTEGO (NCT07333378)
- Testing
- Retention of Vernix Caseosa After Birth, Removal of Vernix Caseosa After Birth
- Where
- 2 sites in Chile
- Volunteers
- 1,383 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Surgical Site Infection, Vaginal Cuff Cellulitis
Prevention of Vaginal Cuff Infection After Hysterectomy by Addition of Vaginal Clindamycin
This study seeks to determine ways to reduce the hospitals surgical site infection rate during hysterectomy operations.
- Conditions
- Surgical Site Infection, Vaginal Cuff Cellulitis, Bacterial Vaginosis
- Trial name
- NCT07888101
- Testing
- Clindamycin Vaginal Gel
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- Baylor Research Institute
Necrotizing Fascitis, Cellulitis
Validation of the Use of the Arteriovenous Tension Difference in CO2 Under Hyperbaric Conditions
The central venous-arterial carbon dioxide tension difference is used daily in intensive care to establish peripheral tissue hypoperfusion, mainly mediated by a low cardiac index.
- Conditions
- Necrotizing Fascitis, Cellulitis, Septic Shock
- Trial name
- SEPTICO2HBO (NCT07492030)
- Testing
- Echography
- Where
- France
- Volunteers
- 74 people
- Sponsor
- University Hospital, Lille
Peritonsillar Abscess, Peritonsillar Cellulitis
Transoral Ultrasound Versus no Transoral Ultrasound in Diagnostic Workup of Peritonsillar Abscess
Peritonsillar abscess (PTA) is a collection of pus between the palatine tonsil and the constrictor muscle. PTA is detected by recognizing characteristics during clinical examination: redness, pain, malaise, trismus, and…
- Conditions
- Peritonsillar Abscess, Peritonsillar Cellulitis, Tonsillitis
- Trial name
- NCT07577232
- Testing
- Transoral Ultrasound
- Where
- 3 sites in Denmark
- Volunteers
- 368 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose…
- Conditions
- Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension
- Trial name
- POPS or POP02 (NCT04278404)
- Testing
- The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Gastroenteritis, Gastrointestinal Diseases
Burden of Recreational Water Illness Due to Exposure to Cyanobacteria and Their Toxins in Freshwater Beaches in Canada
Swimming and other recreational water activities at public beaches are increasingly popular leisure activities among Canadians. However, harmful algal blooms caused by blue-green algae (i.e., cyanobacteria) have also been…
- Conditions
- Gastroenteritis, Gastrointestinal Diseases, Eye Infections, Skin Infections
- Trial name
- NCT06579170
- Testing
- Cyanobacteria exposure during water contact
- Where
- 4 sites in Canada
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Sinusitis, Otitis
Complicated Infections in Otorhinolaryngology
This observational study aims to learn more about complicated infections treated by otorhinolaryngologists. The main questions to answer are: What is the management of complicated sinonasal infections in Ljubljana, Slovenia, What…
- Conditions
- Sinusitis, Otitis, Laryngitis, Lymphadenitis
- Trial name
- ENT_infect (NCT06023550)
- Testing
- Treatment with surgery and/or conservative measures
- Where
- Slovenia
- Volunteers
- 2,550 people
- Sponsor
- University Medical Centre Ljubljana
Respiratory Tract Infections, Urinary Tract Infections
Intravenous Versus Oral Treatment of the Main Acute Infections
Patients admitted to the hospital with acute infections are often treated with intravenous (IV) antibiotics. Around 70% of these infections fall into three categories: respiratory tract infections, urinary tract infections, and…
- Conditions
- Respiratory Tract Infections, Urinary Tract Infections, Cellulitis
- Trial name
- NCT06715306
- Testing
- Oral treatment
- Where
- 7 sites in Denmark
- Volunteers
- 4,000 people
- Sponsor
- University of Southern Denmark
Cellulitis of Leg
Cellulitis Optimal Antibiotic Treatment
To determine whether a short course of oral flucloxacillin (5 days) is non-inferior to a standard course (7 days) in terms of pain over days 6-14 (indicative of persistence or recurrence associated with the symptoms of most…
- Trial name
- COAT (NCT05584007)
- Testing
- Flucloxacillin Only Product in Oral Dose Form
- Where
- United Kingdom
- Volunteers
- 334 people
- Sponsor
- University of Southampton
Acute Disease, Sepsis
Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine
Research in acute care faces many challenges, including enrollment challenges, legal limitations in data sharing, limited funding, and lack of singular ownership of the domain of acute care.
- Conditions
- Acute Disease, Sepsis, Pneumonia, Frailty
- Trial name
- Acutelines (NCT04615065)
- Where
- Netherlands
- Volunteers
- 35,000 people
- Sponsor
- University Medical Center Groningen
Orbital Cellulitis
Dexamethasone vs. Placebo in Children and Youth Hospitalized for Orbital Cellulitis
The goal of this pilot randomized controlled trial is to understand whether we can successfully conduct a larger definitive clinical trial in the future.
- Trial name
- VISION (NCT07345819)
- Testing
- Dexamethasone 0.3mg/kg
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- The Hospital for Sick Children
Urinary Tract Infection, Cellulitis
Perspectives on Antibiotics and Tracking Symptoms in Children
The study will assess families' perspectives and decision-making regarding the duration of oral antibiotic courses prescribed to children (4-17 years) who present with uncomplicated bacterial infections at the Royal Children's…
- Conditions
- Urinary Tract Infection, Cellulitis, Impetigo, Pharyngitis
- Trial name
- PATSy (NCT07093749)
- Testing
- Garmin Smartwatch
- Where
- Australia
- Volunteers
- 300 people
- Sponsor
- Murdoch Childrens Research Institute
Acute Complicated Appendicitis With Peri-appendiceal Abscess or Phlegmon
Peri-appendiceal Abscess and Phlegmon in Acute Complicated Appendicitis Patients
This study aim to analyze the clinical data of patients who underwent emergency appendectomy for acute complicated appendicitis with peri-appendiceal abscess or phlegmon, identify factors influencing the post-operative length of…
- Trial name
- NCT06490185
- Testing
- Clinical data collection
- Volunteers
- 150 people
- Sponsor
- Shanghai Zhongshan Hospital
Urinary Tract Infection, Cellulitis
Clinical Efficacy of Stopping Oral Antibiotics When Symptoms Stop, Compared to 'Finishing the Course'
The aim of the StopStop@HITH study is to see if stopping antibiotics when symptoms stop is as good as finishing the course of antibiotics.
- Conditions
- Urinary Tract Infection, Cellulitis, Respiratory Tract Infections, Lymphadenitis
- Trial name
- StopStop@HITH (NCT07532941)
- Testing
- Antibiotics for duration of symptoms, Antibiotics for duration of prescribed course
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- Murdoch Childrens Research Institute
Fungal Skin Infection, Tinea Corporis
Clinical, Dermoscopic, and Mycological Evaluations of Resistant Dermatophytosis
Dermatophytosis is a common superficial infection of the skin, hair, or nails caused by dermatophyte, it is colloquially known as ringworm or tinea infection and affects an estimated one in five people in their lifetime
- Trial name
- NCT07796854
- Testing
- Direct microscopic KOH examination, Culture:, Antifungal susceptibility testing:
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Acute Tonsillitis, Peritonsillar Abscess
A Single Dose of Intravenous Penicillin as an Adjunct to Oral Penicillin in the Treatment of Acute Tonsillitis, Peritonsillar Phlegmon, and Peritonsillar Abscess
Background Tonsillar infections are highly prevalent and are associated with substantial morbidity, including severe sore throat, dysphagia, and general malaise.
- Conditions
- Acute Tonsillitis, Peritonsillar Abscess, Peritonsillar Cellulitis
- Trial name
- EGO PEN (NCT07896226)
- Testing
- Benzylpenicillin
- Where
- Denmark
- Volunteers
- 154 people
- Sponsor
- Tejs Ehlers Klug
Skin Infection, Staphylococcal Infections
Adjunctive Clindamycin for the Treatment of Skin and Soft Tissue Infections, a Randomized Controlled Trial
This is an exploratory study to evaluate the effect of adjunctive clindamycin in the treatment of skin and soft-tissue infections due to Staphylococcus aureus in patients from Sierra Leone.
- Conditions
- Skin Infection, Staphylococcal Infections, Staphylococcus Aureus Infection
- Trial name
- SoTiClin (NCT05899140)
- Testing
- Clindamycin, Standard of care
- Where
- Sierra Leone
- Volunteers
- 100 people
- Sponsor
- Frieder Schaumburg
Odontogenic Infection, Maxillofacial Infection
Moxifloxacin Versus Clindamycin in the Management of Odontogenic Maxillofacial Infectious Processes
Investigators are conducting a trial to compare moxifloxacin against clindamycin for dental infections that spread to the face and jaw.
- Conditions
- Odontogenic Infection, Maxillofacial Infection, Cellulitis, Cellulitis of Face
- Trial name
- NCT07810244
- Testing
- Clindamycin, Moxifloxacin (400 mg)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Nishtar Medical University
Cellulitis, Skin Disease, Infectious
Naproxen Versus Placebo as Adjunct Treatment of Cellulitis
Cellulitis is a painful bacterial skin infection commonly seen in Canadian emergency departments. Cellulitis has a negative impact on patients' quality of life and productivity.
- Conditions
- Cellulitis, Skin Disease, Infectious, Infection, Skin and Soft Tissue Infections (SSTIs)
- Trial name
- NVP (NCT07665476)
- Testing
- enteric-coated naproxen, Cephalexin Tablets
- Where
- Canada
- Volunteers
- 884 people
- Sponsor
- Ottawa Hospital Research Institute