Clinical trials: Central Corneal Thickness
Corneal and Endothelial Cell Measurements
Comparative Study of Specular Microscope for Cell Density, Coefficient of Variation, Hexagonality and Corneal Thickness
The primary objective of this clinical study is to collect clinical data to support an FDA 510(k) submission for the Nidek Specular Microscope CEM-530.
- Trial name
- NCT01729975
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nidek Co. LTD.
Cataract
Corneal Edema After Phacoemulsification
To compare the impact of two phacoemulsification techniques (subluxation versus divide-and-conquer) on postoperative corneal edema at postoperative hour 1 and day 4.
- Trial name
- COPHA (NCT03689270)
- Testing
- Subluxation, Divide and conquer
- Volunteers
- 96 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Cataract, Phacoemulsification
Correlation Between Postoperative Central Corneal Thickness and Endothelial Damage After Cataract Surgery
To study correlation between postoperative corneal edema and endothelial cell loss after cataract surgery by microcoaxial phacoemulsification.
- Trial name
- ECOCHI (NCT03972670)
- Volunteers
- 85 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Endothelial Corneal Dystrophy
Predictive Factors of Good Results After Primary Descemet's Membrane Endothelial Keratoplasty (DMEK)
Aim: Identify predictive factors of good results after primary Descemet's Membrane Endothelial Keratoplasty (DMEK) in Fuchs Endothelial Corneal Dystrophy (FECD).
- Trial name
- GOODRMEK (NCT04469933)
- Volunteers
- 102 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Normal Tension Glaucoma
Intraocular Pressure Reduction Efficacy of Rhopressa and Lumigan in Normal Tension Glaucoma
Glaucoma is the second leading cause of blindness and the first leading cause of irreversible vision loss worldwide. The intraocular pressure (IOP) is the only modifiable risk factor for all the spectrum of glaucoma.
- Trial name
- NTG (NCT04981886)
- Testing
- Netarsudil Ophthalmic, Bimatoprost Ophthalmic
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Salus University
Neurotrophic Keratitis, Neurotrophic Keratopathy
Open-label Trial to Evaluate Efficacy and Safety of rhNGF on Corneal Thickness Via AS-OCT in Neurotrophic Keratitis
Primary Objective: To assess the efficacy of cenegermin-bkbj (20 mcg/mL) ophthalmic solution on overall corneal thickness via AS-OCT in patients with stage 3 neurotrophic keratitis with respect to change from baseline at weeks 4…
- Conditions
- Neurotrophic Keratitis, Neurotrophic Keratopathy, Corneal Ulcer
- Trial name
- IMAGO (NCT06411145)
- Testing
- OXERVATE® 0.002%
- Sponsor
- Dompé Farmaceutici S.p.A
Corneal Endothelial Cell Loss
Comparative Study of Specular Microscopes for Endothelial and Corneal Cell Measurements
The primary objective of this clinical study is to collect clinical data to support an FDA 510(k) submission for the Topcon Specular Microscope SP-1P.
- Trial name
- NCT02138266
- Testing
- Topcon Specular Microscope SP-1P, Konan Specular Microscope CELLCHEK XL
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Topcon Medical Systems, Inc.
Intraocular Pressure, Central Corneal Thickness
Reliability of Dynamic Contour Tonometry (DCT)
Study wants to test reliability Dynamic Contour Tonometry (DCT) in measuring intraocular pressure (IOP) and Ocular Pulse Amplitude (OPA).
- Trial name
- DCT (NCT01579331)
- Testing
- DCT (PASCAL© Tonometer) IOP and OPA measurement
- Where
- Italy
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Catanzaro
Benign Intracranial Hypertension
Axial Length and Central Corneal Thickness in Benign Intracranial Hypertension
Patients in for treatment of benign intracranial hypertension will undergo two tests that are not routinely performed for these patients: central corneal thickness and axial length of the eye.
- Trial name
- NCT02541994
- Testing
- Pachette3, Lenstar-Think
- Volunteers
- 5 people
- Sponsor
- Ochsner Health System
Vernal Keratoconjunctivitis
Evaluation of Central Corneal Thickness in Patients With Vernal Keratoconjunctivitis Using Topical Steroids
This prospective observational cohort study aims to assess changes in central corneal thickness (CCT) in vernal keratoconjunctivitis (VKC) patients using topical steroids.
- Trial name
- NCT06913790
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Superior University
Open Angle Glaucoma, Ocular Hypertension
Central Corneal Thickness and 24-hour Fluctuation of Intraocular Pressure
The purpose of this study is to determine whether 24-hour fluctuation of intraocular pressure (IOP) is associated with central corneal thickness (CCT) in subjects with ocular hypertension or open angle glaucoma and in age-matched…
- Trial name
- CCT-IOP (NCT00941525)
- Testing
- Latanoprost
- Where
- Greece
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Corneal Edema, Visual Acuity
Effect of Topical Brimonidine on Post Cataract Surgery Corneal Edema
Most patients undergoing cataract surgery suffer from corneal edema after the surgery. Brimonidine drops are a well known and safe Anti-glaucoma medication.
- Trial name
- NCT00800423
- Testing
- Brimonidine Tartrate 0.2%, Timolol maleate 0.5%
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Rabin Medical Center
Fuchs Endothelial Corneal Dystrophy, Cataract (Post-operative Cataract Surgery Follow-up)
Postoperative CCT in FECD vs. Non-FECD
This single-centre, prospective, controlled, non-interventional observational clinical study aims to characterize early postoperative corneal thickness behaviour after routine phacoemulsification cataract surgery in eyes with…
- Trial name
- NCT07731945
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Vienna Hospital Association