Clinical trials: Central Line Catheters
CLABSI - Central Line Associated Bloodstream Infection, CRBSI - Catheter Related Bloodstream Infection
Neonatal Catheter Lock for Infection Prevention
For newborns admitted to Neonatal Intensive Care Units (NICUs), one of the main risk factors for late-onset sepsis is the presence of a central venous catheter (CVC), which is often essential for the administration of medications…
- Conditions
- CLABSI - Central Line Associated Bloodstream Infection, CRBSI - Catheter Related Bloodstream Infection, Neonatal Sepsis, Late-Onset
- Trial name
- Neo-CLIP (NCT07585188)
- Testing
- Taurolidine 2% lock, Normal saline lock
- Where
- Italy
- Volunteers
- 576 people
- Sponsor
- University of Turin, Italy
Catheterization, Peripheral
Peripherally Inserted Central Catheter Insertion Site and Complication Rate in Neonates
This study examines whether there is an association between the PICC insertion site and the complications necessitating PICC removal in neonates admitted to neonatal intensive care unit.
- Trial name
- NCT03474978
- Testing
- Peripherally Inserted Central Venous Cather (PICC)
- Where
- Canada
- Volunteers
- 320 people
- Sponsor
- University of Calgary
Central Venous Catheters, Ultrasound Guidance
Does the Needle-pilot Device Improve the Success of Vascular Catheterization Compared to the Classical Ultrasound-guided Technique
Real-time ultrasound guidance for central venous catheter catheterism is recommended in order to reduce complication, in particular for internal jugular site1.
- Trial name
- NEEDLE-VISIO (NCT04463147)
- Testing
- Needle-pilotTM device
- Where
- France
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Venous Thrombosis
Study on the Incidence of Early Deep Vein Thrombosis After Peripherally Inserted Central Catheter Insertion
Deep Vein Thrombosis (DVT) is one of the most important complications after Peripherally Inserted Central Catheter (PICC) insertion. This study goals are to understand when and why DVT develops.
- Trial name
- DVT-PICC (NCT02752984)
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
End-Stage Kidney Disease, Renal Dialysis
The Impact of Different Citrate Concentrations as Locking Solutions on Development of Biofilm and Function of Hemodialysis Catheters
Evidence that supports using certain concentration of trisodium citrate as a locking solution for hemodialysis catheters has not yet been established.
- Conditions
- End-Stage Kidney Disease, Renal Dialysis, Central Venous Catheter, Biofilms
- Trial name
- NCT03683563
- Testing
- 4% sodium citrate, 30% sodium citrate
- Where
- Slovenia
- Volunteers
- 50 people
- Sponsor
- University Medical Centre Ljubljana
No Specific Conditions Under Study. Primary Focus: Adult Subjects Who Require PICC Placement
Assessment of the Precision of the Sherlock 3CG Tip Positioning System
Phase I determine the location of the peripherally inserted central catheter (PICC) tip upon observation of maximum p-wave amplitude Phase II determine the precision of PICC placement in the Sherlock 3CG group versus the standard…
- Trial name
- STAT-PICC (NCT01275430)
- Testing
- Sherlock 3CG, Blind Placement
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- C. R. Bard
Infusions, Intravenous, Administration, Intravenous
Digital Transformation of Continuity of Care for Peripherally Inserted Central Catheters: SpadCare Experience
The study focuses on patients who require outpatient infusion of therapy ("Infusions, Intravenous"[Mesh]) "Administration, Intravenous"[Mesh] ("Home Infusion Therapy"[Mesh]) "Parenteral Nutrition, Home"[Mesh] via a peripherally…
- Conditions
- Infusions, Intravenous, Administration, Intravenous, Home Infusion Therapy, Parenteral Nutrition, Home
- Trial name
- SpadCare (NCT06905119)
- Testing
- Digital Transformation of Continuity of Care for Peripherally Inserted Central Catheters
- Where
- Spain
- Volunteers
- 201 people
- Sponsor
- Fundacion Miguel Servet
Nurse Education
The Effect of Virtual Simulation Games on Nursing Students' Knowledge, Skills, Confidence and Satisfaction in CVC Care
This study aims to evaluate the effect of virtual simulation games on developing nursing students' knowledge, skills, confidence, and satisfaction levels regarding central venous catheter care and management.
- Trial name
- CVC (NCT07378384)
- Testing
- Virtual Simulation Game-Based Education, Standard Nursing Education
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Zeynep Kandemir özsoy
Central Venous Catheter, Infant
Optimal Insertion Depth of Left Internal Jugular Vein Catheter in Infants
We previously performed a study to create formula for the optimal insertion depth of left internal jugular vein catheter in infant, which was registered at cris.nih.go.kr.
- Trial name
- NCT03025178
- Testing
- 4Fr central venous catheter insertion
- Where
- South Korea
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Adult Cancer Patients, Right Atrial Clot
A Study of Cardiac Magnetic Resonance Imaging (CMR) for Evaluating Catheter-Associated Right Atrial Clot in People With Cancer
The researchers are doing this study to see how well cardiac magnetic resonance imaging (CMR) scans can be used to examine the properties of central venous catheter-associated right atrial clot (RA clot).
- Trial name
- NCT07549477
- Testing
- Cardiac MRI
- Where
- 7 sites in United States
- Volunteers
- 150 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Infection Associated With Catheter, Bacteremia
Safety and Efficacy Study of Ethanol Locking to Prevent Central Line Infection in Premature Neonates
Appropriate delivery of adequate nutrition and medications in premature infants often requires central venous access in the form of a special IV called a PICC (peripherally inserted central catheter).
- Conditions
- Infection Associated With Catheter, Bacteremia, Sepsis
- Trial name
- NCT01365312
- Testing
- Ethanol lock, Heparinized saline
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- East Carolina University
Hemodialysis Access Failure, Kidney Disease, End-Stage
Low-Dose Apixaban Added to Standard Heparin Lock Versus Heparin Lock Alone to Prevent Tunneled Hemodialysis Catheters Dysfunction (APICATH-HD)
This randomized, single-center, PROBE trial evaluates whether adding low-dose apixaban (2.5 mg orally every 12 hours) to standard intraluminal heparin lock prolongs primary functional patency of tunneled hemodialysis catheters…
- Conditions
- Hemodialysis Access Failure, Kidney Disease, End-Stage, Hemodialysis Catheter
- Trial name
- APICATH-HD (NCT07404345)
- Testing
- Apixaban, Heparin sodium lock solution
- Where
- Mexico
- Volunteers
- 54 people
- Sponsor
- Hospital Civil de Guadalajara
Thrombosis, Catheter
The Risk Assessment Scale for Peripherally Inserted Central Venous Catheter (PICC) Related Thrombosis in Cancer Patients
The aim of this study is to compare the accuracy and clinical predictive value of the Michigan Risk Score, Caprini Risk Assessment Model , and Maneval Scale （Chinese version）in predicting PICC-related thrombosis.
- Trial name
- NCT05977452
- Testing
- Michigan Risk Score, Caprini Risk Assessment Model , Maneval scale
- Where
- China
- Volunteers
- 281 people
- Sponsor
- Sun Yat-sen University
Thrombosis
Pediatric Catheter-related Thrombosis Imaging Study
This protocol will serve as a pilot study to determine the validity and feasibility of contrast enhanced magnetic resonance imaging (MRI) without and with contrast and/or ultrasound (US) for detection of catheter related deep…
- Trial name
- AESOP (NCT01137578)
- Testing
- Ultrasound, Magnetic Resonance Imaging with Contrast, Magnetic Resonance Imaging without Contrast
- Where
- 26 sites in United States, Argentina and 7 more
- Volunteers
- 151 people
- Sponsor
- Bristol-Myers Squibb
Infection
Antimicrobial Catheter Lock Solution for the Treatment of Central Line Associated Bloodstream Infection (CLABSI)
A CVC is a sterile flexible tube that allows a drug to flow from a bottle or bag directly into a patient's bloodstream. CVCs may cause infections when bacteria gets into the catheter and enters the bloodstream.
- Trial name
- NCT01539343
- Testing
- Antimicrobial Solution
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- M.D. Anderson Cancer Center
Anxiety, Pain
Musical Intervention and Patient's Anxiety During Central Venous Catheter Insertion in the Intensive Care Unit
Intensive care unit patients who have to undergo central venous catheter insertion and are able to hear explanations and to gave consent, will be randomized to either usual care during catheter insertion or to a musical…
- Trial name
- MUSIC-CAT (NCT03398525)
- Testing
- usual care, Musical intervention
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Critical Ill Patients, Central Venous Catheter
Development and Validation of an Ultrasound-Based Difficult Cannulation Risk Score
Ultrasound-guided internal jugular vein (IJV) catheterization is widely used in critically ill patients. Despite ultrasound guidance, difficult catheterization and first-pass failure remain clinically important and may increase…
- Trial name
- ROTATE-ICU (NCT07764562)
- Testing
- IJV Catheterization
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Antalya Health Sciences University
Pain, Anxiety
The Effect of Using a Kaleidoscope During Central Venous Catheter Dressing Changes in Children With Cancer
Many medical interventions, including the dressing of central venous catheters, a common procedure used for children with cancer, cause anxiety and pain in children. This can adversely affect their care and recovery.
- Trial name
- NCT04924023
- Testing
- kaleidoscope application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Mehmet Akif Ersoy University
Home Parenteral Nutrition, Central Venous Catheter
Taurolidine Lock in Long Term Parenteral Nutrition
Taurolidine alone or in combination with citrate have been proposed for locking the catheter to reduce the number of catheter infections.
- Trial name
- NCT02009189
- Testing
- 2% Taurolidine Lock, 1.35% Taurolidine
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Stanley Dudrick's Memorial Hospital
Nosocomial Infections
ED Residents MBP During CVC Placement: Sim Lab Based Training
1. Baseline performance in maximal barrier precaution technique of Emergency Medicine (EM) residents, certified in CVC placement, is poor 2.
- Trial name
- EM CVC MBP (NCT00791583)
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center