Clinical trials: Central Nervous Injury
Spinal Cord Injuries
Intermittent Catheterization in Spinal Cord Injured Men
The aim of this investigation is to study how the position of different catheters affect drainage of the bladder.
- Trial name
- NCT02230540
- Testing
- SelfCath (comparator), Product A SelfCath and urine bag, Conveen Security+, Product B SelfCath and urine bag, Conveen Contour
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- Coloplast A/S
Acquired Brain Injury, Alexia
Treatment for Reading and Writing Deficits Following Acquired Brain Injury
Many people with acquired brain injuries have deficits in reading decoding, reading comprehension, and written expression. Alexia is a phenomenon in which a person who previously could read has trouble doing so after having…
- Conditions
- Acquired Brain Injury, Alexia, Agraphia
- Trial name
- NCT03662243
- Testing
- Multicomponent reading and writing treatment
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Quality Living, Inc.
Traumatic Brain Injury
Eye Movement Recordings in the Diagnosis of Traumatic Brain Injury
The study investigates whether the use of eye movement recordings can provide a reliable diagnostic of previously undiagnosed mild traumatic brain injury (blast and impact) in Operations Enduring Freedom or Iraqi Freedom…
- Trial name
- NCT00875589
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Spasticity
A Study to Assess the Safety and Efficacy of IPN10200 in Adult Participants With Upper Limb Spasticity.
The purpose of the study is to assess the safety and efficacy of increasing doses of Corabotase (also known as IPN10200) with the aim to evaluate the Pharmacodynamics (PD) profile of Corabotase and to establish the total…
- Trial name
- LANTIMA (NCT04752774)
- Testing
- Corabotase, Dysport
- Where
- 81 sites in United States, Austria and 12 more
- Volunteers
- 240 people
- Sponsor
- Ipsen
SCI - Spinal Cord Injury
Long-term Follow-up for Epidural Stimulation in SCI
The goal of this study is to understand long-term effects of spinal cord stimulation in individuals who have a spinal cord injury. The main aims are to: 1.
- Trial name
- NCT07042815
- Testing
- Epidural Stimulation Programs
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Kessler Foundation
Spinal Cord Injuries
Combined Magnetic Stimulation and Ultrasound for Detrusor Overactivity in SCI
This clinical trial aims to investigate whether the combination of high-frequency sacral nerve root magnetic stimulation and bladder-directed ultrasound therapy can effectively improve detrusor overactivity (involuntary bladder…
- Trial name
- NCT07704268
- Testing
- Transcranial Magnetic Stimulation (TMS) Device /Ultrasound therapy device
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Shengjing Hospital
Encephalopathy, Asphyxia Newborns
Brain Activity During Birth for Prediction of Newborns at Risk for Brain Injury
The purpose of this study is early identification of asphyxiated newborns through eeg starting in the delivery room.
- Trial name
- NCT02445417
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sharp HealthCare
Traumatic Brain Hemorrhage
Traumatic Acute Subdural Haematoma: Management and Outcome
Traumatic acute subdural haematomas (ASDHs) are common pathological entity in neurosurgical practice . The frequency of (ASDHs) has been proposed as approximately 10-20% of patients admitted with traumatic brain injury(TBI)…
- Trial name
- NCT03971240
- Testing
- evacuation of traumatic acute subdural hematoma
- Volunteers
- 39 people
- Sponsor
- Assiut University
Hemiparesis, Cerebral Palsy
VR Error Augmentation for Bimanual Task Exercise
This project is a continuing study from the FEATHERS project (NCT02290353) which focuses on developing novel home therapy program for persons with hemiparesis.
- Conditions
- Hemiparesis, Cerebral Palsy, Acquired Brain Injury
- Trial name
- FEATHERSv2 (NCT03766711)
- Testing
- Physical Therapy
- Where
- 2 sites in Canada
- Volunteers
- 5 people
- Sponsor
- University of British Columbia
Brain Injuries
Behavioral Trial Studying Programmed Training to Improve Advocacy Skills for Individuals With Traumatic Brain Injury
The Midwest Advocacy Project (MAP) is a community-based multiple-site randomized practical behavioral trial of advocacy skill training for individuals with traumatic brain injury (TBI), their families, and significant others.
- Trial name
- MAP (NCT01002677)
- Testing
- Advocacy training curriculum, Self-directed
- Where
- 3 sites in United States
- Volunteers
- 234 people
- Sponsor
- Mayo Clinic
Chronic Pain, Headache, Migraine
Feasibility of Using Holographic Memory Resolution® (HMR) in Patients/Clients With Pain
Study Purpose: This study will explore the feasibility of administering Holographic Memory Resolution® (HMR) to adults who are experiencing chronic pain for 6 months or more.
- Conditions
- Chronic Pain, Headache, Migraine, Stress Disorders, Post-Traumatic
- Trial name
- NCT05001399
- Testing
- Holographic Memory Resolution® (HMR)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Billings Clinic
Traumatic Brain Injury, Brain Injuries
Remote Ischemic Conditioning in Traumatic Brain Injury
Traumatic brain injury (TBI) is a leading cause of death among trauma patients accounting for one-third of all trauma mortalities.
- Conditions
- Traumatic Brain Injury, Brain Injuries, Brain Trauma, Brain Injuries, Traumatic
- Trial name
- MOTION (NCT03899532)
- Testing
- Remote Ischemic Conditioning, No-Remote Ischemic Conditioning
- Where
- United States
- Sponsor
- University of Arizona
Neurodegenerative Diseases
Clinical Effect of Acupuncture in Neurodegenerative Diseases on Traumatic Brain Injury Patients
Traumatic brain injury (TBI) is an altered brain function caused by an external force, which may annually have 69 million incidence cases all over the world.
- Trial name
- NCT05839132
- Testing
- Acupuncture
- Where
- Taiwan
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Cerebrovascular Accident, Hip Fracture
The Relationship Between Pet Therapy and "Well-being" in Geriatric Rehabilitation In-patients
In -patients in a geriatric rehabilitation unit, will participate in structured therapy with guinea-pigs on the assumption that the therapy will reduce anxiety and improve the outcome of their rehabilitation.
- Trial name
- NCT01234844
- Testing
- care of guinea pigs, guinea pigs
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Meir Medical Center
Traumatic Brain Injury
Descriptive and Prospective Study of Sphincter Disorders in the Severe Traumatic Brain Injury Population
Severe traumatic brain injury (TCI), defined by an initial GCS of ≤ 8 and/or admitted to a neurosurgical intensive care unit, are responsible for diffuse brain lesions that can lead to multiple deficits, including impairment of…
- Trial name
- TCG (NCT05163262)
- Testing
- sexuality questionnaire
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Spinal Cord Injuries, Neurogenic Bowel
Exoskeleton Neurogenic Bowel Dysfunction Study
The purpose of the study is to assess the effects of exoskeleton training on neurogenic bowel disorders in spinal cord injury/ disease.
- Trial name
- NCT05176327
- Testing
- Exoskeleton training with Ekso NR
- Where
- Hong Kong
- Volunteers
- 10 people
- Sponsor
- The University of Hong Kong
Traumatic Brain Injury
Noninvasive Intracranial Pressure Waveforms Assessment in Traumatic Brain Injury
In clinical practice, hospital admission of patients with altered level of consciousness ranging from drowsiness to decreasing response states or coma is extremely common.
- Trial name
- NCT06423469
- Testing
- Noninvasive ICP monitoring
- Where
- 4 sites in Brazil
- Volunteers
- 345 people
- Sponsor
- Sergio Brasil, MD
Central Cord Injury Syndrome, Central Spinal Cord Syndrome
Intermittent Positive-Pressure Breathing Effects in Patients With High Spinal Cord Injury
Background: To determine whether intermittent positive-pressure breathing (IPPB) improved lung compliance, work of breathing, and respiratory function in patients with recent high spinal cord injury (SCI).
- Trial name
- NCT00476866
- Testing
- intermittent positive-pressure breathing (IPPB)
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University of Versailles
Neuropathic Pain
To Evaluate Long-Term Safety and Efficacy of Pregabalin in the Treatment of Neuropathic Pain After Spinal Cord Injury.
To evaluate long-term safety and efficacy of pregabalin in the treatment of neuropathic pain after spinal cord injury.
- Trial name
- NCT00141375
- Testing
- Pregabalin
- Where
- 7 sites in Australia
- Volunteers
- 132 people
- Sponsor
- Pfizer
Optic Nerve Diseases, Optic Nerve Injuries
Paraorbital-Occipital Alternating Current Stimulation Therapy for Optic Neuropathy (MCT_optnerve)
Aim is to validate that non-invasive brain stimulation can increase cortical excitability in the visual system. The investigators assess if transcranial alternating current stimulation (tACS) can improve visual field size in…
- Conditions
- Optic Nerve Diseases, Optic Nerve Injuries, Optic Neuropathies
- Trial name
- NCT01280877
- Testing
- tACS
- Where
- 4 sites in Germany
- Volunteers
- 90 people
- Sponsor
- University of Magdeburg
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