Clinical trials: Central Obesity
Obesity
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of PB-718 Injection in Chinese Obese Subjects.
The trial is conducted in a single center, randomized, double blind, placebo controlled, dose increasing design. To evaluate the safety, tolerability, pharmacokinetics(PK) characteristics, efficacy and immunogenicity of PB-718…
- Trial name
- NCT06147544
- Testing
- PB-718
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- PegBio Co., Ltd.
Central Venous Catheters, Obesity
A Trial to Study the Influence of Ultrasound Guidance on the Complications of Central Catheter
Central venous catheterization (CVC) in ICU is very common. It is associated with many complications. These complications are now well identified in the literature. They are primarily mechanical, infectious and thrombotic events.
- Trial name
- CATHETER (NCT01154465)
- Testing
- Central Venous Catheter Insertion, Ultrasound guidance
- Where
- France
- Volunteers
- 264 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Obesity
Pilot Study to Evaluate A Novel Gastric Space Occupying Device
This will be an observational, prospective, non-randomized, pilot study to gain initial device experience on a novel space-occupying device in persons who are overweight or obese. No formal hypothesis testing will be conducted.
- Trial name
- NCT01444274
- Testing
- Obalon Gastric Balloon(s)
- Where
- Mexico
- Volunteers
- 10 people
- Sponsor
- Obalon Therapeutics, Inc.
Obesity, Overweight
Community Outreach - Obesity Prevention Trial (CO-OPT)
The purpose of this research is to investigate the effectiveness of a community health worker-based program as an adjunct to clinical services regarding childhood obesity management.
- Conditions
- Obesity, Overweight, Children
- Trial name
- CO-OPT (NCT02024360)
- Testing
- Patient navigation
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Denver Health and Hospital Authority
Atrial Fibrillation, Obesity
Effectiveness And Safety Of Oral Anticoagulants Among Obese Patients With Non-Valvular A-Fib In VA Patients With Medicare
The overall objective of this analysis is to understand patient characteristics, the use of treatment, and clinical outcomes among obese (overweight) and severely obese patients with non-valvular atrial fibrillation (NVAF) who…
- Conditions
- Atrial Fibrillation, Obesity, Anticoagulants
- Trial name
- NCT04681482
- Testing
- Apixaban
- Where
- United States
- Volunteers
- 107,383 people
- Sponsor
- Pfizer
Cardiac Arrest, Inflammation
Immunoinflammatory Response in Post Cardiac Arrest Syndrome (PCAS)
This is a prospective, observational study to investigate molecular mechanisms mediating the systemic inflammatory process, and changes to metabolism, and their impact on brain injury, survival, and functional outcomes after…
- Conditions
- Cardiac Arrest, Inflammation, Obesity, Hypoxic Ischemic Encephalopathy (HIE)
- Trial name
- PCAS (NCT02664831)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- MaineHealth
Fitness Trackers, Cardio Vascular Disease
Effects of Wearable Device Functions and Health Coaching on Device-measured Movement Behaviours and Cardiometabolic Risk Factors in Adults With Central Obesity
This study is a randomized controlled trial. The objective of this study is to investigate: 1. the effects of 1-year evidence-based interventions incorporating wearable device functions alone on device-measured movement…
- Conditions
- Fitness Trackers, Cardio Vascular Disease, Physical Activities, Exercise
- Trial name
- NCT07379970
- Testing
- Fitbit Wearable Device, Lifestyle Coaching Program
- Where
- Hong Kong
- Volunteers
- 133 people
- Sponsor
- The University of Hong Kong
Childhood Obesity
SDSU MOVE/Me Muevo Project
The purpose of this study is to design, implement, and evaluate a recreation site-based obesity prevention \& control intervention for 7-9 year old children and their families by targeting physical activity and dietary behaviors.
- Trial name
- NCT00381069
- Testing
- Family & Community Recreation Center Intervention
- Where
- United States
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Aging, Obesity
Effects of Testosterone Gel on Carbohydrate and Lipid Metabolism In Elderly Obese Men
A. HYPOTHESES: In older men low testosterone levels, abdominal obesity and elevated fasting insulin who are at risk for the cardiovascular complications such as heart attack and stroke. 1.
- Conditions
- Aging, Obesity, Insulin Resistance, Hypogonadism
- Trial name
- NCT00365794
- Testing
- Topical testosterone gel 10 g/day
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Environmental Exposures, Child Development
HOME Study (Health Outcomes and Measures of the Environment Study)
The goal of the HOME Study is to quantify the impact of low-level fetal and early childhood exposures to environmental toxicants including lead, mercury, and other metals, pesticides, polychlorinated biphenyls (PCBs), persistent…
- Conditions
- Environmental Exposures, Child Development, Lead and Injury Reduction
- Trial name
- NCT00129324
- Testing
- Lead Hazard Control Intervention, Injury Hazard Control Intervention
- Where
- United States
- Volunteers
- 468 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Obesity, Metabolic Disease
Diet and Fat Mass After Traumatic Spinal Cord Injury
This is a randomized clinical controlled trial (RCT) to investigate the impact of a personalized nutritional intervention on functional and clinical outcomes the first year after traumatic spinal cord injury.
- Conditions
- Obesity, Metabolic Disease, Spinal Cord Injuries
- Trial name
- NCT04109586
- Testing
- Personalized nutritional therapy
- Where
- Norway
- Volunteers
- 62 people
- Sponsor
- Sunnaas Rehabilitation Hospital
Prader-Willi Syndrome
Study to Evaluate Efficacy, Safety, and Tolerability of RGH-706 in Prader-Willi Syndrome
RGH-706 is a novel, potent, and orally active MCHR1 antagonist drug candidate discovered and being developed by Gedeon Richter Plc. for weight management.
- Trial name
- NCT05322096
- Testing
- RGH-706
- Where
- 23 sites in United States, Czechia and 3 more
- Volunteers
- 39 people
- Sponsor
- Gedeon Richter Plc.
Overweight or Obesity
Multicenter Trial Investigating Performance and Safety of the Medical Device SiPore21®
The present clinical investigation is a randomized, double-blinded, placebo-controlled, multicenter international trial, planned to be conducted in Poland, Romania and Slovakia.
- Trial name
- SHINE (NCT06087822)
- Testing
- IMD SiPore21®
- Where
- 27 sites in Poland, Romania and 1 more
- Volunteers
- 318 people
- Sponsor
- Sigrid Therapeutics AB
Obesity
Our Year of Healthy Living (Formative Research & Intervention)
The purpose of this study is to evaluate the effect of a 7-month social marketing program - Healthy Me, Healthy We (previously called Our Year of Healthy Living) - in improving preschool children's (3-4 years) diet and physical…
- Trial name
- NCT02330354
- Testing
- Healthy Me, Healthy We
- Where
- United States
- Volunteers
- 2,293 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Spinal Cord Injuries, Obesity
Spinal Cord Injury Model Systems (SCIMS) - Education Module
The purpose of this study is to find out if receiving education regarding increased risks of cardiometabolic disease helps subjects understand these risks and how these risks participants' health.
- Conditions
- Spinal Cord Injuries, Obesity, Cardiometabolic Syndrome
- Trial name
- NCT06003686
- Testing
- PVA Consumer Guide, WebMD
- Where
- 3 sites in United States
- Volunteers
- 250 people
- Sponsor
- University of Miami
Metabolic Syndrome, Abdominal Obesity
Copenhagen Obesity Risk Assessment Study
The aim of the present study is to assess the effect of a high intake of industrially produced trans fatty acids for 16 weeks on abdominal obesity and risk markers of type 2 diabetes and heart disease in healthy, moderately…
- Conditions
- Metabolic Syndrome, Abdominal Obesity, Heart Disease, Type 2 Diabetes
- Trial name
- COBRA (NCT00655902)
- Testing
- Trans fat (soy bean oil), Control fat (sunflower oil)
- Where
- Denmark
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Overweight, Obese
Evaluating the Effects Two Diets Combined With Exercise in Persons With Abdominal Obesity (The SHAPE5 Study)
Abdominal obesity, which is affected by a lack of physical activity and excess weight, put people at an increased risk of cardiovascular disease.
- Conditions
- Overweight, Obese, Sedentary, Abdominal Obesity
- Trial name
- SHAPE5 (NCT00990457)
- Testing
- Weight Loss Diets Plus Exercise
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cardiovascular Diseases, Hypertension
Developing a Learning COmmunity to Increase eNgagemeNt and Enrollment in Cardiovascular Clinical Trials (CONNECT)
The CONNECT: "Developing a learning COmmunity to increase eNgagemeNt and Enrollment in cardiovascular Clinical Trials" is comprehensive, participant-centered learning platform designed to increase diversity in cardiovascular…
- Conditions
- Cardiovascular Diseases, Hypertension, Diabetes Type 2, Stroke
- Trial name
- CONNECT (NCT06347484)
- Testing
- EHR-informed Recruitment Method of Contact, Educational Text-Messages and Connection to Cardiovascular Research Opportunities
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Sarcopenia, Sarcopenic Obesity
Effects of a Multi-intervention Programme for the Elderly
1. To develop a multiactivity training programme. 2. To explore the effect of this programme on sarcopenia, sarcopenic obesity, cognitive impairment and Parkinson's disease. 3.
- Conditions
- Sarcopenia, Sarcopenic Obesity, Dementia
- Trial name
- NCT05720416
- Testing
- protein supplementation, muscle strength training, usual care
- Where
- Taiwan
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Central Taiwan University of Science and Technology
Cluster Headache, Obesity
DBS of the Third Ventricle for Cluster Headache and Obesity
Study of Deep Brain Stimulation of the Third ventricle in Cluster Headache and Obesity treatment.
- Trial name
- DBS V3 (NCT02782533)
- Testing
- Deep Brain Stimulation V3
- Where
- France
- Volunteers
- 13 people
- Sponsor
- University Hospital, Grenoble