Clinical trials: Central Pain Syndrome
HIV Disease, Chronic Pain
Toward Safer Opioid Prescribing for Chronic Pain in High Risk Populations
The overarching plan for TOWER is to develop and test an algorithmic version of the Center for Disease Control Guidelines (CDCG) tailored for a specific primary care setting, the HIV primary care clinic.
- Trial name
- TOWER (NCT03669939)
- Testing
- Communication Strategy, Standard of Care
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders
Studying Fentanyl in Patients With Cancer
RATIONALE: Studying blood samples from cancer patients undergoing pain treatment in the laboratory may help doctors learn more about how pain drugs work in the body.
- Conditions
- Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders, Leukemia, Lymphoma
- Trial name
- NCT00899951
- Testing
- fentanyl citrate, pharmacological study
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Subacromial Pain Syndrome
Dry Needling and Manipulation vs. Mobilization, Exercise and Interferential Electrotherapy for Shoulder Impingement (Subacromial Pain Syndrome)
The purpose of this research is to compare two different approaches for treating patients with shoulder impingement (subacromial pain syndrome): electric dry needling and spinal manipulation versus impairment-based mobilization…
- Trial name
- NCT03168477
- Testing
- dry needling, spinal manipulation, mobilization
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- Alabama Physical Therapy & Acupuncture
Failed Back Surgery Syndrome, Spinal Stenosis
Value of Three-dimensional Rotational Epidurography on Percutaneous Epidural Adhesiolysis
Conventional epidurography (CE) is thought to have insufficient usefulness on percutaneous epidural adhesiolysis (PEA). The investigators aimed to evaluate the association between the outcome of PEA and three…
- Trial name
- NCT04216992
- Testing
- Cone beam computed tomography
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Postpoliomyelitis Syndrome
Arm Cycling to Improve Fitness in Polio Survivors
The aim of this study is to investigate the effect of upper limb cardiovascular training on fitness, energy cost of walking, fatigue and pain in polio survivors.
- Trial name
- NCT01271530
- Testing
- Upper Limb Ergometry
- Where
- Ireland
- Volunteers
- 55 people
- Sponsor
- Royal College of Surgeons, Ireland
Sleep Initiation and Maintenance Disorders, Anxiety
HIRREM Developmental Study
The purpose of this study is to explore the functional and physiological effects associated with the use of High-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM), as supplemental care, for symptoms of…
- Conditions
- Sleep Initiation and Maintenance Disorders, Anxiety, Post-Traumatic Stress Disorder, Hot Flashes
- Trial name
- NCT02709369
- Testing
- HIRREM
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Wake Forest University Health Sciences
Neuropathic Pain, Postherpetic Neuralgia
Simultaneous Engagement of Networks for Alleviating Pain (SENAP)
This trial is investigating the acceptability and efficacy of PFM-guided cortical stimulation for the treatment of central neuropathic pain.
- Trial name
- NCT07057206
- Testing
- PFM-guided cortical stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Minnesota
Complex Regional Pain Syndrome
Comparison of Dorsal Column Stimulation to Dorsal Root Ganglion Stimulation for Complex Regional Pain Syndrome
Complex Regional Pain Syndrome (CRPS) is a constellation of pain symptoms which are associated with impairment in mood, social and physical function.
- Trial name
- NCT03794024
- Testing
- The Nuvectra Algovita Dorsal Column Spinal Cord Stimulator, The Axium Neurostimulator System
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- The Cleveland Clinic
Renal Pelvis Cancer, Restless Legs Syndrome
Gabapentin and Risk of Pancreatic Cancer and Renal Cancer (GPRD)
High doses of gabapentin are associated with pancreatic acinar cell tumors in rats, but there has been no post marketing pancreatic carcinogenicity signal with gabapentin as reported by spontaneous reports in the Adverse Events…
- Conditions
- Renal Pelvis Cancer, Restless Legs Syndrome, Epilepsy, Neuropathic Pain
- Trial name
- NCT01138124
- Testing
- Gabapentin prescriptions
- Volunteers
- 54,202 people
- Sponsor
- GlaxoSmithKline
Acute Myocardial Infarction, Angina Pectoris
Effects of Telmisartan on Ischemic Cardiovascular Events in High-risk Hypertensive Patients
This study is aimed to investigate whether treatment with Telmisartan is more effective than Candesartan in reducing the ischemic cardiovascular events in high-risk patients with cardiovascular disease.
- Conditions
- Acute Myocardial Infarction, Angina Pectoris, Myocardial Ischemia, Acute Coronary Syndrome
- Trial name
- KCPS (NCT00863980)
- Testing
- Micardis (Telmisartan), Blopress (Candesartan)
- Where
- 32 sites in Japan
- Volunteers
- 1,500 people
- Sponsor
- Kyoto Prefectural University of Medicine
Fibromyalgia, Primary, Fibromyalgia
Pain Phenotypes in Patients With Fibromyalgia Syndrome
Fibromyalgia Syndrome (FMS); is a complex syndrome characterized by many symptoms such as chronic widespread pain, fatigue and sleep disorders, cognitive dysfunctions and psychiatric disorders.
- Conditions
- Fibromyalgia, Primary, Fibromyalgia, Chronic Pain Syndrome, Pain, Neuropathic
- Trial name
- NCT05941780
- Testing
- Pain classification method
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Kutahya Health Sciences University
Migraine, Healthy
Molecular and Functional PET-fMRI Measures of Analgesia in Migraine
The placebo effect is a phenomenon that has experienced major advances of its understanding in the last decade. However, mechanisms of placebo analgesia in chronic pain patients have yet to be compared to healthy subjects.
- Trial name
- NCT01970943
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cluster Headache - Episodic and Chronic
Safety and Efficacy Study of SOM230 s.c. in Cluster Headache
The purpose of this study was to determine if SOM230 is safe and effective for the treament of cluster headache.
- Trial name
- NCT02619617
- Testing
- SOM230
- Where
- 4 sites in United States, Germany and 1 more
- Volunteers
- 28 people
- Sponsor
- Novartis Pharmaceuticals
Malignant Pain, Non-malignant Pain
To Demonstrate Equivalence in Analgesic Efficacy & Bowel Function Between OXN PR Higher Dose & Lower Dose Tablet Strengths in Subjects With Non-cancer or Cancer Pain
This study is aimed to demonstrate equivalence between combinations of lower strength OXN PR tablets (OXN PR LST) and single higher strength OXN PR tablets (OXN PR HST) taken at the same overall daily dose.
- Trial name
- NCT02321397
- Testing
- Oxycodone, Naloxone
- Where
- Germany
- Volunteers
- 155 people
- Sponsor
- Mundipharma Research GmbH & Co KG
Shoulder Impingement
Effects of PNF on Shoulder Pain in Paraplegic Manual Wheel Chair Users
This project was a Randomized control trial conducted to check the Effects of Proprioceptive Neuromuscular Facilitation on Shoulder Pain due to chronic impingement syndrome in paraplegic Manual Wheelchair users after Spinal Cord…
- Trial name
- NCT04967911
- Testing
- Rhythmic stabilization exercises, conventional treatment
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Migraine, Abdominal Pain
Migraine and Recurrent Abdominal Pain in Children
This study will evaluate a new model for assessing and treating migraine and recurrent abdominal pain in children. The model combines behavioral techniques such as relaxation training with biologic components such as thermal…
- Trial name
- NCT00060619
- Testing
- thermal biofeedback, relaxation training, cognitive coping skills
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cancer
Multiple Symptoms in Cancer Patients a Cross Sectional Multi Center Study
This study will assess the occurrence of multiple symptoms in cancer patients of 5 German university hospitals. Primary goal of the study is to assess the prevalence of multiple symptoms and related symptom clusters (e.g.
- Trial name
- ProKID (NCT01317355)
- Where
- Germany
- Volunteers
- 697 people
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Rotator Cuff Lesion, Subacromial Impingement Syndrome
Investigation of the Effect of Central Sensitization Symptom Severity on Steroid Injection Results in Shoulder Pain
The aim of this study was to investigate the effect of the presence and severity of pre-treatment central sensitization on the results of subacromial/ intra-articular shoulder injection in patients with rotator cuff…
- Conditions
- Rotator Cuff Lesion, Subacromial Impingement Syndrome, Shoulder Pain, Chronic Pain
- Trial name
- NCT06404125
- Testing
- Range of Motion of Shoulde Joint, Hand Grip Test, Numeric Rating Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Shoulder Pain, Tendonitis
Treatment of Calcific Tendinitis of the Rotator Cuff
The purpose of this study is to determine whether the combination of removal of the calcification in calcific tendinitis of the shoulder (supraspinatus and/or infraspinatus tendon) by aspiration with a needle and syringe…
- Conditions
- Shoulder Pain, Tendonitis, Calcinosis, Shoulder Impingement Syndrome
- Trial name
- NCT02419040
- Testing
- Barbotage, Corticosteroid injection
- Where
- Norway
- Volunteers
- 220 people
- Sponsor
- Vestre Viken Hospital Trust
Painful Bladder Syndrome, Interstitial Cystitis
Study of URG101 in Painful Bladder Syndrome and Interstitial Cystitis
A double-blind, placebo-controlled study to evaluate changes in pain, urgency and urinary frequency following administration of URG101 compared to placebo.
- Conditions
- Painful Bladder Syndrome, Interstitial Cystitis, Bladder Pain Syndrome
- Trial name
- NCT00517868
- Testing
- URG101
- Where
- 6 sites in United States
- Volunteers
- 28 people
- Sponsor
- Urigen