Clinical trials: Central Post-stroke Pain
Stroke, Pain
Botulinum Toxin A for Shoulder Pain After Stroke
Shoulder pain after stroke is a very common, causing significant morbidity disease. Subacromial and subdeltoid (SASD) bursitis are common causes of pain or disability of the shoulder joint in stroke patients.
- Trial name
- NCT02618603
- Testing
- Botulinum toxin A, Triamcinolone Acetonide
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Sir Run Run Shaw Hospital
Central Post-Stroke Pain
Treatment of Post-Stroke Central Pain
To evaluate the short-term analgesic efficacy of stSCS combined with pharmacotherapy compared with pharmacotherapy alone in patients with CPSP, measured by Numerical Rating Scale (NRS) score immediately after treatment.
- Trial name
- NCT07593313
- Testing
- stSCS+Gabapentin or Pregabalin (with optional Duloxetine or Amitriptyline), Gabapentin or Pregabalin (with optional Duloxetine or Amitriptyline)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Nanchong Central Hospital
Stroke
A Study of Post-Stroke Pain and Fatigue: Clinical Evaluation and Treatment Effect
The investigators anticipate this research will shed light on metric properties of outcome measures of pain and fatigue and the effects of the combined therapy for stroke patients.
- Trial name
- NCT01913509
- Testing
- Combined Therapy of FES and BAT, Conventional Rehabilitation
- Where
- Taiwan
- Volunteers
- 110 people
- Sponsor
- Chang Gung University
Hemiplegia, Stroke
The Effect of Shoulder Problems on Balance in Hemiplegic Patients
Shoulder problems are among the most common complications in hemiplegic patients and may impair shoulder biomechanics, negatively affecting mobility, transfers, and self-care.
- Trial name
- NCT07159178
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul Aydın University
Stroke
Dry Needling for Spasticity in Stroke
Stroke is the leading cause of physical disability due to the presence of spasticity. Different needling techniques, including Botulinum Toxin A are proposed for management of spasticity; however results are conflicting.
- Trial name
- NCT02377804
- Testing
- Dry needling, Physical Therapy, stainless steel needles (0.3mm x 50mm)
- Where
- 2 sites in Spain
- Volunteers
- 20 people
- Sponsor
- Universidad Rey Juan Carlos
Complex Regional Pain Syndromes
Investigation of the Efficacy of Transcranial Magnetic Stimulation in Patients Developing Complex Regional Pain Syndrome Type 1 in the Upper Extremity During the Subacute-Chronic Period After Ischemic Stroke
The aim of our study is to investigate transcranial magnetic stimulation (TMS) as a treatment option in Complex Regional Pain Syndrome, disseminate it to a broader patient population, and simultaneously demonstrate its…
- Trial name
- NCT06215079
- Testing
- The Magstim Rapid2 Plus Magnetic Stimulator (Magstim, Whitland, Dyfed, UK), conventional rehabilitation program
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ankara City Hospital Bilkent
Healthy, Thalamic Pain Syndrome
Gait Parameters Analysis in Post-stroke Patients and in Elderly Fallers
A large proportion of falls in older people occurs when walking. Most studies have recently demonstrated correlation between the variations in spatiotemporal gait parameters and fall risk in elderly and in several diseases.
- Conditions
- Healthy, Thalamic Pain Syndrome, Fallers
- Trial name
- GAITRITE (NCT01443052)
- Testing
- Gait analysis
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hemiplegia
Effectiveness of NeuroMuscular Taping on Painful Hemiplegic Shoulder
Painful Shoulder Syndrome is a frequent complication after stroke occurring in between 5% and 84% of patients, often having a strong impact on their well-being and resulting in delays achieving rehabilitative objectives.
- Trial name
- NCT02254876
- Testing
- Standard physical therapy program, NeuroMuscular Taping (NMT)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Bologna
Chest Pain, Pneumonia
The Effect of Exercise on Physical Function and Health in Older People After Discharge From Hospital
The aim of this study is to investigate the effect of a multi-component exercise program on physical function, physical activity and health-related quality of life (HRQOL) in older people recently discharged from hospital.
- Conditions
- Chest Pain, Pneumonia, Transient Ischemic Attack, Stroke
- Trial name
- OLPADIS (NCT02905383)
- Testing
- Exercise
- Where
- Norway
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Chronic Neuropathic Pain, Post-Stroke Pain
Transcranial Magnetic Stimulation for Chronic Neuropathic Pain
Chronic neuropathic pain is defined as pain caused by a lesion or disease of the somatosensory nervous system. It is highly prevalent, debilitating, and challenging to treat.
- Conditions
- Chronic Neuropathic Pain, Post-Stroke Pain, Trigeminal Neuralgia, Nerve Injury
- Trial name
- NCT05593237
- Testing
- High Frequency rTMS, Low Frequency rTMS
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, San Francisco
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Central Post-stroke Pain
Structural and Functional Grey and White Matter Changes in Patients With Pain Disorders
The goal of this observational study is to examine the association between exact lesion location and presence of thalamic CPSP (Central post-stroke pain) in a larger number of patients after thalamic stroke.
- Trial name
- NCT05679297
- Testing
- Quantitative sensory testing (QST), Magnetic resonance imaging (MRI), Clinical interview/exam
- Where
- Switzerland
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Post-stroke Spasticity
Pain During Injection With Botulinum Toxin in Post-stroke Spasticity Treatment
The aim of the study was to analyze which step of the procedure of toxin botulinum injection is the most painful between skin break-in, electric stimulation, injection and needle withdrawal.
- Trial name
- DOLOTOX (NCT03251521)
- Testing
- pain rating during injection with botulinum toxin
- Volunteers
- 46 people
- Sponsor
- University Hospital, Grenoble
Central Post-stroke Pain, Neuropathic Pain
Thalamic-Burst-DBS for Neuropathic Pain
Central post-stroke pain (CPSP) is a neuropathic pain syndrome and one of the major sequelae after ischemic or hemorrhagic cerebral stroke.
- Trial name
- NCT05204472
- Testing
- Burst DBS, Tonic DBS
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Shoulder Pain, Stroke
Hemiplegic Shoulder Pain and Rotator Cuff Injuries
Hemiplegic shoulder pain (HSP) is one of most complications after stroke. HSP would impede rehabilitation programs and the motor recovery of affected upper extremity.
- Conditions
- Shoulder Pain, Stroke, Rotator Cuff Injuries
- Trial name
- NCT02465853
- Testing
- Hyaluronic Acid, Physiological saline solution, physical therapy and occupational therapy
- Where
- Taiwan
- Volunteers
- 42 people
- Sponsor
- Chang Gung Memorial Hospital
Shoulder Pain, Hemiplegia
Observational Study of Hemiplegic Shoulder Pain After Recent Stroke
This is an observational study to address the following questions. 1. How many people develop stroke-shoulder pain within 3 days of stroke? 2. How many people have stroke shoulder pain at 8-10 weeks after stroke? 3.
- Conditions
- Shoulder Pain, Hemiplegia, Stroke
- Trial name
- SPARS (NCT02574000)
- Testing
- ShoulderQ which is a shoulder pain questionnaire, Clinical shoulder examination
- Where
- United Kingdom
- Volunteers
- 163 people
- Sponsor
- St George's, University of London
Stroke
Deep Dry Needling for the Management of Post-stroke Spasticity
Stroke is the leading cause of physical disability, particularly due to the presence of spasticity. Different needling techniques, including the use of Botulinum Toxin A are proposed for the management of spasticity.
- Trial name
- NCT01950338
- Testing
- Dry needling
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Universidad Rey Juan Carlos
Pain, Stroke
Symptom Control and Physiological Effects of Reflexology Applied After Stroke
This study is designed as a randomized controlled intervention with a pre-test-post-test design to evaluate the effect of reflexology on pain, physiological parameters, and sleep quality in stroke patients.
- Conditions
- Pain, Stroke, Reflexology, Nursing
- Trial name
- NCT07295626
- Testing
- Reflexology Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Hakkari Universitesi
Post-stroke Shoulder Pain and Spasticity
Randomized DB Controlled Trial of Botulinum Toxin A in Hemiplegic Shoulder Pain and Spasticity
The purpose of this study is to evaluate whether botulinum toxin type A injected into muscles around the shoulder is effective in treating shoulder pain and improving function in patients with shoulder pain and involuntary muscle…
- Trial name
- NCT00661089
- Testing
- Botulinum Toxin Type A - OnabotulinumtoxinA
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Shirley Ryan AbilityLab