Clinical trials: Central Sensitisation
Central Nervous System Sensitization, Pain
Effect of High-dose Naloxone Infusion on Pain and Hyperalgesia in Patients Following Groin-Hernia Repair.
Recent studies have focused on the role of endogenous opioids on central sensitization. Central sensitization is known to be impaired or altered in chronic pain conditions, as fibromyalgia or chronic tension headache.
- Conditions
- Central Nervous System Sensitization, Pain, Hyperalgesia
- Trial name
- NCT01992146
- Testing
- Target-controlled naloxone-infusion
- Where
- Denmark
- Volunteers
- 9 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Chronic Pain Syndrome, Sensitization, Central
Management of Chronic Non-Cancer Pain With Non-Pharmacological Therapies
A randomized controlled clinical trial will be conducted, involving a psychoeducational activity as the intervention. There will be a control group of patients with non-cancer chronic pain who will continue their usual treatment.
- Conditions
- Chronic Pain Syndrome, Sensitization, Central, Quality of Life, Patient Empowerment
- Trial name
- NCT06440668
- Testing
- Chronic Pain Management Workshop with Non-Pharmacological Therapies
- Where
- Spain
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Hospital San Juan de Dios del Aljarafe de Sevilla
Shoulder Pain
Central and Peripheral Sensitization, and Pain Contributing Factors in Shoulder Pain Patients and Healthy People
Compared to healthy subjects, central and peripheral sensitization will be investigated in patients with non-specific shoulder pain, since no data is available at the moment.
- Trial name
- NCT05360589
- Where
- Italy
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Thoracic Outlet Syndrome
Motivational Interviewing in Thoracic Outlet Syndrome
The goal of this clinical trial is to learn if motivational interviewing (MI) works to improve symptoms in people with thoracic outlet syndrome (TOS).
- Trial name
- NCT07668206
- Testing
- Motivational Interviewing, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Hacettepe University
Lipedema, Central Sensitisation
Investigation of Central Sensitization and Associated Factors in Patients With Lipedema
This study aims to investigate the presence of central sensitization and its associated parameters in patients with lipedema. Lipedema is a chronic and hereditary condition that primarily affects the lower extremities in women…
- Trial name
- NCT06770634
- Testing
- Pain-Pressure Threshold Measurement With an Algometer, Central Sensitization Inventory, Numeric Rating Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Chronic Migraine
Effect of Nebulized Dexmedetomidine on Central Sensitization and Chronification in Migraine
Migraine is a debilitating neurological disorder characterized by recurrent headaches episodes, often accompanied by amplified perception of multiple sensory inputs such as cutaneous allodynia, photophobia, and phonophobia.
- Trial name
- NCT07769255
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 146 people
- Sponsor
- Beni-Suef University