Clinical trials: Central Serous Chorioretinopathy
Central Serous Chorioretinopathy
Multimodal Imaging in Central Serous Chorioretinopathy
This study aims to assess the contribution of the multimodal imaging, combining a routine examination using Optical Coherence Tomography (OCT) with an imaging procedure using adaptive optics retinal camera.
- Trial name
- IMO (NCT02889185)
- Testing
- RTX1 IMAGIN EYE retinal camera
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Central Serous Chorioretinopathy (CSC)
Faricimab for Chronic Central Serous Chorioretinopathy: A Randomized Sham-Controlled Trial
Dysregulation of the Angiopoietin-2 (Ang-2)/Tyrosine kinase with Immunoglobulin-like and EGF-like domains 2 (Tie-2) signaling pathway has been implicated in choroidal vascular instability and RPE dysfunction in Central serous…
- Trial name
- NCT07681167
- Testing
- Faricimab
- Volunteers
- 50 people
- Sponsor
- Singapore National Eye Centre
Choroidal Ischemia, Vitelliform Macular Dystrophy
Sildenafil for Treatment of Choroidal Ischemia
The hypothesis of this study is to determine if there is a benefit afforded by the use of systemic Sildenafil to patients with choroidal and retinal degenerations and dystrophies, such as vitelliform degeneration, dry and…
- Conditions
- Choroidal Ischemia, Vitelliform Macular Dystrophy, Age-related Macular Degeneration, Central Serous Retinopathy
- Trial name
- NCT04356716
- Testing
- Sildenafil, Standard of Care Sildenafil, Ocular Coherence Tomography-Angiography (OCT-A)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Columbia University
Chorioretinopathy, Central Serous
Crocin Supplementation in CSCR
Preclinical and clinical evidence support the protective effect of crocin on different pathologic pathways involved in central serous chorioretinopathy (CSCR).
- Trial name
- NCT04936490
- Testing
- Crocin
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Shiraz University of Medical Sciences
Central Serous Chorioretinopathy
Eplerenone For the Treatment of Chronic Central Serous Chorioretinopathy
The aim of the study is to determine the efficacy and safety in treating patients with chronic central serous chorioretinopathy with the drug eplerenone.
- Trial name
- NCT02153125
- Testing
- Eplerenone
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Central Serous Chorioretinopathy
Efficacy and Safety of Intravitreal Aflibercept Injection for Subacute Central Serous Chorioretinopathy
Central serous chorioretinopathy (CSC) is a self-limiting disease that usually associated with good visual prognosis. In some cases, however, CSC may persist and result in permanent retinal or retinal pigment epithelium (RPE)…
- Trial name
- NCT01971190
- Testing
- Intravitreal Aflibercept injection, Half-fluence photodynamic therapy
- Where
- 6 sites in South Korea
- Volunteers
- 43 people
- Sponsor
- Asan Medical Center
Central Serous Chorioretinopathy
The Effect of Therapy With Bevacizumab in Chronic Central Serous Chorioretinopathy
The pathophysiology of central serous chorioretinopathy remains controversial. traditional treatment is laser photocoagulation or photodynamic therapy.Recently Bevacizumab (Avastin, Genetech),an antibody to vascular endothelial…
- Trial name
- NCT00864773
- Testing
- intravitreal injection with anterior paracentesis
- Volunteers
- 10 people
- Sponsor
- Hallym University Medical Center
Central Serous Chorioretinopathy
Eplerenone, Aflibercept and Topical Nepafenac Serous Foveal Deta Chment in Central Serous Chorioretinopathy
describing the influence of; combined Eplerenone, intravitreal Aflibercept, and topical Nepafenac; on serous foveal detachment in eyes with CSCR
- Trial name
- CSCR (NCT05847049)
- Testing
- Eplerenone , Intravitreal Aflibercept and Topical nepafenac therapy
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Dar El Oyoun Hospital
Central Serous Chorioretinopathy
Bevacizumab Versus Micropulse in Central Serous Chorioretinopathy (CSC)
The purpose of this study is to evaluate the clinical efficacy of an initial subthreshold retinal micropulselasercoagulation versus a single intravitreal 1.5mg bevacizumab injection in central serous choriretinopathy, as the…
- Trial name
- NCT00802906
- Testing
- subthreshold micropulselaser, bevacizumab
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Central Serous Chorioretinopathy
Central Serous Chorioretinopathy: Etiology, Course and Prognosis
Pathogenesis of central serous chorioretinopathy is not entirely understood yet, therefore further investigations are needed. During this study patients with an acute episode of central serous chorioretinopathy are observed with…
- Trial name
- NCT01378130
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Central Serous Chorioretinopathy
Eplerenone for the Treatment of Central Serous Chorioretinopathy
To test the effect oral eplerenone versus placebo in patients with central serious chorioretinopathy .
- Trial name
- NCT01990677
- Testing
- 25mg Eplerenone
- Where
- 10 sites in United States
- Volunteers
- 108 people
- Sponsor
- Wills Eye
the Presence of Subretinal Fluid (SRF)
Green Subthreshold Laser Therapy for Chronic Central Serous Chorioretinopathy.
Chronic Central Serous Chorioretinopathy (CSCR) is a vision-threatening retinal disorder characterized by persistent subretinal fluid due to choroidal vascular hyperpermeability and retinal pigment epithelium (RPE) dysfunction.
- Trial name
- NCT07020793
- Testing
- green subthreshold laser therapy
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- Federico II University
Central Serous Chorioretinopathy
Eplerenone for Central Serous Chorioretinopathy
The goal of the study is to examine the short-term effects and safety of a systemic anti-aldosterone medication, eplerenone, in a small group of patients with central serous chorioretinopathy (CSCR).
- Trial name
- NCT01822561
- Testing
- Eplerenone 50mg
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Tufts Medical Center
Chronic Central Serous Chorioretinopathy
Ranibizumab Versus Low-fluence Photodynamic Therapy in the Treatment of Chronic Central Serous Chorioretinopathy
The purpose of this study is to compare the efficacy and safety of intravitreal ranibizumab injection versus low-fluence PDT in the treatment of chronic CSC.
- Trial name
- NCT01325181
- Testing
- Verteporfin, ranibizumab
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Jang Won Heo
Choroidal Neovascularization, Myopia
Intravitreal Bevacizumab vs.Combination Therapy for CNV Due to Other Than AMD
Anti-VEGF therapy has been proven efficacious for the wet (neovascular) form of macular degeneration and may be beneficial for the treatment of choroidal neovascularization (CNV) due to other causes.
- Conditions
- Choroidal Neovascularization, Myopia, Punctate Inner Choroidopathy (PIC), Multifocal Choroiditis
- Trial name
- CNV (NCT01256580)
- Testing
- Bevacizumab (Avastin; Genentech, Inc.), Bevacizumab, Dexamethasone, Verteporfin Photodynamic Therapy
- Sponsor
- Massachusetts Eye and Ear Infirmary
Chronic Central Serous Chorioretinopathy
Prospective Randomized Controlled Treatment Trial for Chronic Central Serous Chorioretinopathy
Chronic central serous chorioretinopathy (CSC) is a relatively frequent eye disease that often occurs in patients in the professionally active age range.
- Trial name
- PLACE (NCT01797861)
- Testing
- Half-dose photodynamic therapy (PDT), Micropulse laser (ML) treatment
- Where
- 5 sites in France, Germany and 2 more
- Volunteers
- 140 people
- Sponsor
- Radboud University Medical Center
Macular Edema, Radiation Retinopathy
Episcleral Dexamethasone for Treatment of Macular Edema and Inflammatory Disorders of the Posterior Pole
This phase I trial will assess primarily the safety and secondarily anti-inflammatory effect of Episcleral Dexamethasone in patients suffering from macular edema and other disorders of the retina, choroid and vitreous.
- Conditions
- Macular Edema, Radiation Retinopathy, Branch Retinal Vein Occlusion, Epiretinal Membrane
- Trial name
- NCT04120311
- Testing
- Episcleral Dexamethasone
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Targeted Therapy Technologies, LLC
Personality Type
Persona of Central Serous Chorioretinopathy
Purpose: Central serous retinopathy (CSCR) is characterized by macular detachment due to thickened choroid mostly affecting young men under perceived stress.
- Trial name
- CSCR (NCT02819622)
- Where
- Lebanon
- Volunteers
- 83 people
- Sponsor
- Rafic Hariri University Hospital
Retinal Disease
Evaluation and Treatment of Patients With Retinal Disease
This study offers evaluation and treatment for patients with certain diseases of the retina (the layer of light-sensitive tissue that lines the inside of the eyeball).
- Trial name
- NCT00005784
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- National Eye Institute (NEI)
Central Serous Choroidopathy
Micropulse 577nm Laser vs Traditional Laser Treatment in Central Serous Chorioretinopathy
The purpose of this study is to observe whether micropulse laser (MPL) is noninferiority to traditional laser therapy in central serous chorioretinopathy.
- Trial name
- NCT02735213
- Testing
- 577-MPL, TLT
- Where
- China
- Volunteers
- 88 people
- Sponsor
- The Eye Hospital of Wenzhou Medical University