Clinical trials: Central Spinal Cord Syndrome
Spinal Cord Injury
Wheelchair Indoors Curling With SCI patients_RCT
This study investigates if, patients with diagnosed chronic spinal cord injury will benefit from an Indoor Curling Exercise program on their control capabilities of trunk movements and on their intrinsic motivation for physical…
- Trial name
- SCI-RCT (NCT02550834)
- Testing
- Wheelchair indoors curling training
- Where
- 2 sites in Switzerland
- Volunteers
- 32 people
- Sponsor
- HES-SO Valais-Wallis
Spinal Cord Injuries, Multiple Sclerosis
Validity and Reliability of Turkish Version Leg Activity Measure
Patient-filled scales minimize the burden of data collection for clinicians in a clinical setting. Therefore, Leg activity measure, a new self-report measure of active and passive function in the leg, has been developed.
- Conditions
- Spinal Cord Injuries, Multiple Sclerosis, Stroke
- Trial name
- NCT05182411
- Testing
- assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Spinal Cord Injuries
Psychometric Properties of a Mobile Application
Current methods to assess superficial size and area of pressure ulcers are either time-consuming (using Transparency Tracings techniques), costly (computers, softwares), or necessitating to touch the patient's skin (using commun…
- Trial name
- IMITO (NCT04402398)
- Where
- France
- Volunteers
- 59 people
- Sponsor
- University Hospital, Montpellier
Spinal Cord Injuries, Brain Injuries
Pilot Study for Peripheral Neuromuscular Electrical Stimulation of the Quadriceps Muscle
Feasibility study of a new medical device that will evaluate the usability and effectiveness of a cycle ergometer device associated with neuromuscular electrical stimulation (FES cycling).
- Conditions
- Spinal Cord Injuries, Brain Injuries, Muscle Atrophy
- Trial name
- NCT05888714
- Testing
- Experimental FES cycling, Comparator FES cycling, Conventional physical therapy
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- University of Sao Paulo General Hospital
Spinal Cord Injuries
Enhanced Medical Rehabilitation for Spinal Cord Injury
Background: Patient engagement is a cornerstone of patient-centered care. Studies show that an increased level of patient engagement in medical rehabilitation is associated with greater functional recovery.
- Trial name
- EMRSCI (NCT03952416)
- Testing
- Enhanced Medical Rehabilitation (EMR)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries
Ketogenic Diet to Improve Neuro-recovery
The purpose of this project is to determine if 5 weeks of ketogenic (KD, high-fat) diet vs. standard diet (SD) significantly improves motor and sensory function, glycemic function, and functional independence in patients with…
- Trial name
- NCT03509571
- Testing
- Ketogenic Diet, Standard Diet
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Ohio State University
Quadriplegia, Amputations
A Study on the Safety and Functionality of the Implantable Wireless Brain-Computer Interfaces for Motor Rehabilitation
The objective of this study is to evaluate the safety and efficacy of minimally invasive, wireless brain-machine interface system (WRS) in patients with paralysis (resulting from spinal cord injuries, brainstem strokes…
- Conditions
- Quadriplegia, Amputations, Spinal Cord Injuries (SCI), Brainstem Stroke
- Trial name
- STAIR (NCT06944834)
- Testing
- Implant
- Where
- China
- Volunteers
- 5 people
- Sponsor
- Shanghai StairMed Technology Co., Ltd.
Spinal Cord Injury, Acute
Transcutaneous Tibial Nerve Stimulation in Acute Spinal Cord Injury
Most patients with spinal cord injury (SCI) develop neurogenic lower urinary tract dysfunction (NLUTD), one of the most devastating sequelae of SCI which ultimately can lead to renal failure.
- Trial name
- TASCI (NCT03965299)
- Testing
- VERUM TTNS
- Where
- 4 sites in Switzerland
- Volunteers
- 114 people
- Sponsor
- University of Zurich
Spinal Cord Injuries
LTFU Study of Subjects Who Received GRNOPC1
This is a LTFU study for thoracic SCI subjects that were administered GRNOPC1 cells in the main study CP35A007.
- Trial name
- NCT05919563
- Testing
- Magnetic Resonance Imaging (MRI)
- Where
- 3 sites in United States
- Volunteers
- 5 people
- Sponsor
- Lineage Cell Therapeutics, Inc.
Spinal Cord Injury
Epi Stim to Facilitate Standing and Stepping
The overall aim is to assess whether task specific locomotor training and spinal cord electrical stimulation (SCES) can induce neural reorganization of the functionally isolated human spinal cord to improve standing and stepping…
- Trial name
- NCT02339233
- Testing
- Standing and Stepping with spinal cord Epidural Stimulation
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Louisville
Spinal Cord Injuries
Non-invasive Spinal Stimulation as an Adjuvant Therapy for Trunk Control After Pediatric SCI
The overall purpose of this study is to test the efficacy of multi-modal training combining activity-based locomotor training and transcutaneous spinal stimulation (ABLT+scTS) to improve sitting posture and trunk control in…
- Trial name
- NCT05091463
- Testing
- Biostim-5/Neostim transcutaneous spinal stimulator
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Louisville
Spinal Cord Injury, Gut Dysbiosis
Gut Dysbiosis in Spinal Cord Injury Rehabilitation
The goal of this study is to investigate the role of gut microbiota, and related immune biomarkers and metabolites, in the functional recovery of spinal cord injury patients during the subacute phase.
- Conditions
- Spinal Cord Injury, Gut Dysbiosis, Immune Dysfunction
- Trial name
- SCIMBIONT (NCT06892106)
- Where
- Portugal
- Volunteers
- 106 people
- Sponsor
- Centro Academico Clínico Egas Moniz Health Alliance
Traumatic Spinal Cord Injury, Neuropathic Pain
Biomarkers for Pain in Spinal Cord Injury Patients
The investigators propose to compare plasma protein profiles for SCI patients with/without chronic neuropathic pain in order identify biomarker(s) that are associated with this medical condition.
- Trial name
- SCI Pain (NCT00913471)
- Testing
- blood samples
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Spinal Cord Injuries
Patient-therapist INTERaction During RObotic GAIT Rehabilitation After Spinal Cord Injury
INTERROGAIT will disentangle the role of Physical Therapist - Patient (Pht-Pt) interaction in robotic assisted gait rehabilitation in spinal cord injury patients.
- Trial name
- INTERROGAIT (NCT06531304)
- Testing
- Lokomat Robot Assisted Gait Training
- Where
- Italy
- Volunteers
- 55 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Spinal Cord Injury, Traumatic Spinal Cord Injury
Pilot Study of Galantamine to Treat Metabolic Syndrome in People With Chronic Traumatic Spinal Cord Injury (SCI)
The purpose of this research study is to measure the tolerability and preliminary efficacy of a drug, galantamine, to treat metabolic syndrome (MetS) by reducing circulating inflammation in people with spinal cord injury (SCI).
- Conditions
- Spinal Cord Injury, Traumatic Spinal Cord Injury, Paraplegia and Tetraplegia, Metabolic Syndrome
- Trial name
- NCT07625332
- Testing
- Galantamine Hydrobromide Extended Release
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Northwell Health
Spinal Cord Injuries, Autonomic Imbalance
Transcutaneous Spinal Cord Neuromodulation to Normalize Autonomic Phenotypes
This study looks to characterize autonomic nervous system dysfunction after spinal cord injury and identify the potential role that transcutaneous spinal cord stimulation may play at altering neuroregulation.
- Conditions
- Spinal Cord Injuries, Autonomic Imbalance, Autonomic Dysreflexia, Orthostatic; Hypotension, Neurogenic
- Trial name
- NCT04858178
- Testing
- Tests of sympathetic inhibition, Tests of sympathetic activation, Testing of autonomic dysreflexia
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Pressure Ulcers
Implanted Gluteal Stimulation System for Pressure Sore Prevention
This project will evaluate the feasibility of using a fully implanted gluteal stimulation system for the prevention of Pressure ulcers.
- Trial name
- NCT00623948
- Testing
- A fully implanted gluteal stimulation (GSTIM) system
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Spinal Cord Injury
Prospective and Monocentric Study of the Incidence of Venous Thromboembolic Disease (VTE) in Spinal Cord Injury (SCI) Patient Between 3 and 12 Months After SCI
Venous Thromboembolic Disease (VTE) in SCI patients is very common, its prevalence is 60 to 80% against 10-20% in the general population.
- Trial name
- IMATEM (NCT02796235)
- Testing
- Venous Doppler ultrasound of the lower limbs
- Where
- France
- Volunteers
- 81 people
- Sponsor
- Nantes University Hospital
Dysphagia
To Assess the Safety and Efficacy of the 4 Channel NMES Compensatory Medical Device in Swallowing, Multicenter Study
This study is a confirmation study to prepare clinical trials to evaluate the safety and effectiveness of 4-channel electric stimulation therapy devices as a newly developed function for the treatment of dysphagia disorders.
- Trial name
- NCT03670485
- Testing
- 4 channel Electrical Stimulation Device
- Where
- South Korea
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Chronic Pain, Brain Injuries, Traumatic
Telehealth Pain Self-Management for Employed Adults
The E-TIPS trial will evaluate an evidence-based, telehealth pain self-management intervention compared to standard care (a waitlist) for chronic pain in adults with physical disabilities who are employed.
- Conditions
- Chronic Pain, Brain Injuries, Traumatic, Multiple Sclerosis, Spinal Cord Injuries
- Trial name
- E-TIPS (NCT04248725)
- Testing
- E-TIPS
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Washington
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