Clinical trials: Central Spinal Cord Syndrome
Spinal Cord Injuries
Health in Individuals With a Spinal Cord Injury: a Prospective Study
Individuals with a spinal cord injury need to exercise regularly to prevent the decline of health that results from a sedentary lifestyle.
- Trial name
- NCT03743077
- Testing
- Exercise training including inspiratory muscle training
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Columbia University
Spinal Cord Injury, Spinal Cord Injury Cervical
Spine and Brain Stimulation for Movement Recovery After Cervical Spinal Cord Injury
Stimulation of the spinal cord and brain represents a new experimental therapy that may have potential to restore movement after spinal cord injury.
- Trial name
- NCT06867809
- Testing
- Epidural spinal cord stimulation and paired spine and brain stimulation
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Jason Carmel
Traumatic Thoracic Acute Spinal Cord Injury
The INSPIRE Study: Probable Benefit of the Neuro-Spinal Scaffold for Treatment of AIS A Thoracic Acute Spinal Cord Injury
This is an HDE probable benefit, open-label, non- randomized, single-arm, multicenter study to evaluate the safety and probable benefit of the poly(lactic-co-glycolic acid)-b-poly(L-lysine) Scaffold ("Scaffold") in subjects with…
- Trial name
- NCT02138110
- Testing
- Neuro-Spinal Scaffold
- Where
- 8 sites in United States
- Volunteers
- 20 people
- Sponsor
- InVivo Therapeutics
Neuropathic Pain
Teta Burst Versus 10 Hz Repetitive Transcranial Magnetic Stimulation İn Neuropathic Pain: A Sham Controlled Comparison
Neuropathic pain is a common complication after spinal cord injury (SCI), which significantly affects the patient's quality of life and may be resistant to pharmacological treatment.
- Trial name
- NCT06197113
- Testing
- Magstim Rapid2 Magnetic Stimulator
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Ankara City Hospital Bilkent
Spinal Cord Injuries
Early Surgical Intervention Combined With Weight-supported Walking Training
To determine the efficacy of a novel combinatorial treatment involving early surgical intervention and long-term weight-bearing walking training in spinal cord injury (SCI) patients clinically diagnosed as complete or American…
- Trial name
- NCT04034108
- Testing
- Surgical intervention combined with weight-supported ambulation training
- Where
- 2 sites in China
- Volunteers
- 339 people
- Sponsor
- Kunming Tongren Hospital
Spinal Cord Injuries
Heated Vest for Persons With Spinal Cord Injury
Persons with higher levels of spinal cord injury (above the 2nd thoracic vertebrae; tetraplegia) are unable to maintain normal core body temperature (Tcore) when exposed to cool environments.
- Trial name
- NCT03662308
- Testing
- Heated Vest, Non-Heated Vest
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Optic Neuritis, Myelitis
Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)
The purpose of this research is to evaluate if early vs rescue Therapeutic Plasma Exchange (PLEX) treatment algorithm leads to better visual outcomes in severe Optic Neuritis and leads to better neurological disability outcomes…
- Conditions
- Optic Neuritis, Myelitis, Myelitis, Transverse
- Trial name
- TIMELY-PLEX (NCT07100990)
- Testing
- High-dose corticosteroids (HDCS), High-dose corticosteroids (HDCS) and PLEX
- Where
- 35 sites in United States
- Volunteers
- 382 people
- Sponsor
- Mayo Clinic
Chronic, Intractable Back Pain and/or Leg Pain
Clinical Trial of MED HF10™ Spinal Cord Stimulation for the Treatment of Chronic Pain
This is a single-center, prospective, non-randomized exploratory study in subjects with chronic, intractable back pain and/or leg pain per the center's routine practice.
- Trial name
- MED (NCT06897280)
- Testing
- SCS Device Program Setting
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Nevro Corp
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Spinal Cord Injuries (SCI), Urinary Retention
Clinical Trial of Abdominal Breathing for Urinary Retention After Spinal Cord Injury
Randomized controlled trials were conducted in patients with urinary retention after spinal cord injury. The effects of abdominal breathing training on pelvic floor muscle tone, muscle strength and residual urine volume in…
- Trial name
- NCT06964256
- Testing
- Abdominal breathing exercises, Control group: intermittent catheterization, Experimental group: intermittent catheterization
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Qilu Hospital of Shandong University
Secondary Osteoporosis, Spinal Cord Injury
The Efficacy of Denosumab in Incomplete Patients Spinal Cord Injury
The purpose of this study is to determine the usefulness of a drug, denosumab, to prevent the loss of bone in participants legs due to SCI.
- Trial name
- NCT03029442
- Testing
- Denosumab (Prolia)
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Spinal Cord Injuries
Regain of Arm and Hand Movements in Cervical Spinal Stimulation
We will develop a "bottom to top" approach employing animal models and human testing to determine whether or not non-invasive neuro-modulation of the cervical spinal cord concomitant with upper limb rehabilitation driven by…
- Trial name
- tcSCS (NCT07140354)
- Testing
- cervical transcutaneous spinal cord stimulation
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Institut Guttmann
Spinal Cord Injury, Quadriplegia
Electrical Activation of The Diaphragm for Ventilatory Assist
OBJECTIVES: The objectives of this study are to test the Diaphragm Pacing Stimulation (DPS) System for treating chronic ventilatory insufficiency in persons with respiratory muscle paralysis.
- Trial name
- NCT00010374
- Testing
- NeuRx DPS
- Where
- 5 sites in United States, Canada
- Volunteers
- 54 people
- Sponsor
- Synapse Biomedical
Spinal Cord Injury, Mental Health
A Feasibility Trial of an Enhanced Coping-oriented Supportive Programme for Community-dwelling People With Spinal Cord Injury
Spinal cord injury (SCI) is a neurological disorder that leads to "partial or complete loss of people's motor and/ or sensory function below the level of the injury".
- Conditions
- Spinal Cord Injury, Mental Health, Feasibility Studies, Acceptability Study
- Trial name
- NCT07170969
- Testing
- An Enhanced Coping-oriented Supportive Programme (E-COSP) for Community-Dwelling People with Spinal Cord Injury
- Where
- Hong Kong
- Volunteers
- 12 people
- Sponsor
- The Hong Kong Polytechnic University
Spinal Cord Injury
Cethrin in Acute Cervical Spinal Cord Injury
This is a multicenter, randomized, double-blind, placebo-controlled Phase IIb/III study designed to evaluate the efficacy and safety of Cethrin as a treatment for acute cervical spinal cord injury.
- Trial name
- NCT02053883
- Testing
- Cethrin (BA-210)
- Sponsor
- BioAxone BioSciences, Inc.
Spinal Cord Injuries, Pain
Neurofeedback Treatment of Pain in Persons With Spinal Cord Injury (SCI)
A number of studies suggest that training to increase different types of brain waves is related to pain relief. The purpose of the second phase of this study is to see if neurofeedback training might help people with chronic pain…
- Trial name
- NCT00977041
- Testing
- Neurofeedback
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Washington
Spinal Cord Injuries, Physical Disability
Physical Fitness, Exercise Self-efficacy, Physical Activity Level in People With Spinal Cord Injury (SCI)
This is a single blind randomized controlled trial study which will conducted on people with paraplegia wheelchair users. The objectives of this study is to investigates the effects of 16 weeks of 'Graded Exercise Integrated…
- Trial name
- NCT03420170
- Testing
- Graded Exercise Integrated Education, Conventional Physical Therapy
- Volunteers
- 40 people
- Sponsor
- Universiti Teknologi Mara
Pressure Ulcer, Bedsore
Correlation Between Pressure Differences and Micro-vascularization Changes in Bedridden Paraplegic Patient
Paraplegic patients have defective wound healing for sore below the level of spinal lesion. Defect of vascularization of the healing zone certainly participate to this effect.
- Conditions
- Pressure Ulcer, Bedsore, Spinal Cord Injury, Paraplegia
- Trial name
- VASCIP (NCT03114345)
- Testing
- Measurement of interface pressure, Measurement of micro-vascularization related parameters
- Where
- France
- Volunteers
- 4 people
- Sponsor
- University Hospital, Montpellier
Chronic Pain
Targin® for Chronic Pain Management in Patients With Spinal Cord Injury
The study will be investigating the effectiveness of oxycodone-naloxone (brand name Targin®) at treating chronic pain in individuals with spinal cord injury.
- Trial name
- NCT03179475
- Testing
- Oxycodone Naloxone Combination
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of British Columbia
Metastatic Spinal Cord Compression
To Determine Whether it is Feasible to Treat Patients Requiring Urgent Radiotherapy Diagnosed With Metastatic Cord Compression (MSCC) on the Magnetic Resonance Linear Accelerator (MRL) in a Single Appointment and Compare it to the Standard of Care Radiotherapy Pathway
The goal of this clinical trial is to understand whether the Magnetic Resonance Linear Accelerator (MRL) could expedite Radiotherapy treatment for Metastatic Cord Compression (MSCC) by removing the need for a planning CT (pCT)…
- Trial name
- RESONATE (NCT06965101)
- Testing
- Radiotherapy to the spine in a single appointment
- Where
- United Kingdom
- Volunteers
- 72 people
- Sponsor
- The Christie NHS Foundation Trust
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.