Clinical trials: Central Venous Access
Haemodialysis Patients, Blockage of Tunnelled Central Venous Access Device
Pulsatile Flushing Technique in Reducing Blockage of T-CVAD for Haemodialysis Patients
This study investigates the effectiveness of pulsatile flushing techniques in reducing blockage in Tunnelled Central Venous Access Device (T-CVAD) among patients undergoing haemodialysis (HD) treatment at multiple renal centres…
- Conditions
- Haemodialysis Patients, Blockage of Tunnelled Central Venous Access Device, Pulsatile Flushing Technique
- Trial name
- Non-RCT HD (NCT07567456)
- Testing
- Pulsatile Flushing Technique (0.4s pause interval), Pulsatile Flushing Technique (1s pause interval), Bolus Flushing Technique
- Where
- Hong Kong
- Volunteers
- 591 people
- Sponsor
- Queen Elizabeth Hospital, Hong Kong
Difficult Intravenous Access
Central Venous Catheter vs Midline in Difficulty Access Patient - Pilot Trial
Intravenous access is a necessity for nearly all inpatient medical care. Approximately half of hospitalized patients require a peripheral venous catheter (PVC), either to enable administration of medications intravenously or to…
- Trial name
- p-ACCESS-D (NCT06719869)
- Testing
- Midline intravenous catheter, Central Venous Catheter (CVC):
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Region Jönköping County
Bacterial Infections
Frequence of Dressing Change and Bacterial Colonization in Pediatric Intensive Care Unit
This study is non-inferiority trial design.The relationship between whether dressing change 24hrs after CVC (central venous catheter) catheterization and bacterial colonization of the skin.
- Trial name
- NCT04806776
- Testing
- 24hrs dressings change, 7days dressings change
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Children's Hospital of Fudan University
Phlebotomy
Assess Veinplicity Venous Access Device Safety and Effectiveness
The purpose of this study was to examine the Veinplicity Device as an adjunctive IV cannulation tool in subjects with a history of difficult to access veins.
- Trial name
- NCT03109405
- Testing
- Stimulation-assisted venous access, 20 guage cannula for IV, tourniquet optional
- Volunteers
- 200 people
- Sponsor
- Physeon GmbH
Critical Illness, Catheter-Related Infections
Efficacy and Safety of Peripherally Inserted Central Venous Catheters
Central venous access is critical for administering intravenous medications, parenteral nutrition, and fluid therapy in intensive care units (ICUs).
- Conditions
- Critical Illness, Catheter-Related Infections, Upper Extremity Deep Vein Thrombosis, Catheter Obstruction
- Trial name
- NCT07834996
- Volunteers
- 60 people
- Sponsor
- Assiut University
Therapeutic Education Program, Prevention
Adherence and Understanding of a Therapeutic Education Program for Patients With Central Venous Access (EDUVVC)
The aim of this project is to evaluate, in a prospective cohort of PICC line patients, adherence to the project and understanding of the messages.
- Trial name
- EDUVVC (NCT06478849)
- Testing
- QUESTIONNAIRES
- Where
- France
- Volunteers
- 105 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Central Venous Access Devices, Implantable Venous Access Port
Comparison of Transverse and Longitudinal Incisions for Venous Access Port Placement
The aim of the study is to assess whether the direction of skin incision affects pain within the first 24 hours, patient comfort 7 days after the procedure, procedure time, and the occurrence of early complications related to…
- Trial name
- port placement (NCT06766656)
- Testing
- Incision
- Where
- Poland
- Volunteers
- 222 people
- Sponsor
- Jagiellonian University
Surgical Wound
AMBULATE Continued Access Protocol to Evaluate the Cardiva Mid-Bore Venous Vascular Closure System (VVCS)
The objective of the trial is to demonstrate the safety and effectiveness of the Cardiva Mid-Bore Venous Vascular Closure System (VVCS) in sealing femoral venous access sites at the completion of catheter-based procedures…
- Trial name
- NCT03573206
- Testing
- Cardiva Mid-Bore Venous Vascular Closure Device (VVCS)
- Where
- 3 sites in United States
- Volunteers
- 168 people
- Sponsor
- Cardiva Medical, Inc.
Central Line Complication, Central Line-associated Bloodstream Infection (CLABSI)
Compassionate-Use of 4% T-EDTA Lock Solution for Central Venous Lines of Pediatric PN Patients
In this research study we want to learn more about a study drug, tetrasodium sodium EDTA (Kitelock™) for maintaining the patency (blood flow) through a central venous catheter.
- Trial name
- NCT04559334
- Testing
- Tetrasodium EDTA Catheter Lock Solution
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Boston Children's Hospital
Central Venous Catheter Thrombosis
Dialysis Catheter Placement in Patients With Thoracic Central Venous Occlusion
A unique inside-out-access technique with a new CE certified device (Surfacer (R) Bluegrass Vascular, San Antonio, Tx, USA) enables repetitive and confident right-sided placement of central venous catheters in hemodialysis…
- Trial name
- NCT03766828
- Testing
- inside-out-access technique with inside-out access device (Surfacer (R)), access technique including Sharp recanalization
- Where
- Austria
- Volunteers
- 36 people
- Sponsor
- Medical University of Vienna
Arterial Access, Peripheral Access
Correlation of Arterial and Venous Lactate and Base Deficit Values
The purpose of this study is to determine the correlation between pH, base deficit, and lactate values when comparing venous and arterial blood samples in the pediatric population.
- Conditions
- Arterial Access, Peripheral Access, Central Venous Catheter
- Trial name
- NCT02888431
- Testing
- bedside point-of-care device
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Joseph D. Tobias
Cystic Fibrosis
Study About Complications of Totally Implanted Venous Access Devices (TIVADs) in People With Cystic Fibrosis (CF)
Pulmonary infections are the major cause of mortality and morbidity in cystic fibrosis (CF); patients frequently have to take antibiotics which often cannot be given orally or by aerosol but have to be administered intravenously.
- Trial name
- NCT00670579
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Florence
Thrombosis, Venous Thrombosis
Safety and Efficacy Study of Alfimeprase in Subjects With Occluded Central Catheters
The purpose of the study is to compare the safety and effectiveness of alfimeprase to a placebo in restoring function of occluded central catheters.
- Trial name
- NCT00346424
- Testing
- Alfimeprase
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- ARCA Biopharma, Inc.
End-Stage Renal Disease Requiring Haemodialysis, Hemodialysis Access Failure (Disorder)
BONE ANCHORED PORT for Hemodialysis Treatment
A Bone Anchored Port System (BAP) will be implanted in the mastoid bone behind the ear, connected with a double lumen central venous catheter inserted in the jugular vein, and will be used in conjunction with an adapter as a…
- Trial name
- BAP (NCT02069860)
- Testing
- Bone Anchored Port System (BAP)
- Where
- Switzerland
- Volunteers
- 6 people
- Sponsor
- Cendres+Métaux
Thrombosis
Risk of Central Venous Stenosis in Patients With Chronic Renal Failure After IJ Line Placement
The purpose of this study is to compare the difference in thrombosis as a result of internal jugular (IJ) catheters versus peripherally inserted central catheter (PICC) lines.
- Trial name
- NCT01988766
- Where
- United States
- Volunteers
- 1,424 people
- Sponsor
- University of Chicago
Vascular Access Complication
Complications Related to Vascular Access Devices in Home Parenteral Nutrition Patients
Central vascular access devices are required for home parenteral nutrition (HPN). There is few data available concerning their complications in adult HPN patients, and the potential link between venous thromboembolism and…
- Trial name
- CRVADHPNP (NCT05948514)
- Testing
- The complications related to central venous access device
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Hospices Civils de Lyon
Hemodialysis
Prophylactic Antibiotic Treatment in Hemodialysis
The purpose of this study is to assess the efficacy of prophylactic antibiotic treatment on blood stream infections and severe culture negative infections, in patients on newly started hemodialysis(HD), with a central venous…
- Trial name
- PANTHEM (NCT05248620)
- Where
- 7 sites in Denmark
- Volunteers
- 800 people
- Sponsor
- Zealand University Hospital
Central Venous Catheters, Catheter Complications
Complications Associated With Multiple Central Venous Accesses in the Internal Jugular Vein
Patients at risk of significant intraoperative blood loss and/or potential hemodynamic instability often necessitate the placement of two or more central venous catheters, including large bore catheters.
- Conditions
- Central Venous Catheters, Catheter Complications, Catheter Related Complication
- Trial name
- NCT06466226
- Testing
- Multiple central venous lines in two sites separately, Multiple central venous lines in one site (internal jugular vein)
- Volunteers
- 156 people
- Sponsor
- Hospital Nossa Senhora da Conceicao
Children With Central Venous Access
CHG Dressings in Children With Central Lines
The purpose of this study is to determine whether Tegaderm CHG clear dressing reduces the number of unscheduled central catheter dressing changes compared to standard clear Tegaderm IV dressing in pediatric patients between the…
- Trial name
- NCT01955226
- Testing
- Tegaderm CHG clear dressing, Standard clear Tegaderm dressing
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Yale University
Renal Failure
Covered Stents to Treat Hemodialysis Access Stenoses in the Cephalic Arch and Central Veins
Balloon angioplasty is used to open up a narrowing that forms in hemodialysis fistula. Two areas of particular problems are the terminal portion of the cephalic vein near the shoulder and the central veins in the chest.
- Trial name
- NCT01200914
- Testing
- GORE VIABAHN® Endoprosthesis with Heparin Bioactive Surface, PTA alone without use of the GORE VIABAHN
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University Health Network, Toronto