Clinical trials: Central Venous Catheter
Preterm, Pain, Acute
Peripheral Intravenous Central Catheter Intervention in Preterm Infants
This study will be conducted to evaluate the effect of grasping reflex stimulation applied during peripheral intravenous central catheter (PIC) intervention on pain and stress in preterm infants receiving treatment and care in…
- Conditions
- Preterm, Pain, Acute, Stress, Nursing Caries
- Trial name
- NCT05359809
- Testing
- Graspin Palmar Reflex Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ataturk University
RRMM
A PK, Safety and Tolerability Study of Peripheral and Central Infusion of Melflufen in RRMM Patients
This is a randomized, two-period, cross-over Phase 2 study, comparing PK, and assessing safety and tolerability and efficacy of peripheral and central intravenous administration of melflufen in patients with RRMM.
- Trial name
- PORT (NCT04412707)
- Testing
- Melphalan, Dexamethasone
- Where
- 10 sites in United States, Bulgaria and 3 more
- Volunteers
- 27 people
- Sponsor
- Oncopeptides AB
Atrial Fibrillation
Randomized Trial of Two Ablation Catheters in Paroxysmal Atrial Fibrillation
Atrial fibrillation (AF) is a chaotic heart rhythm of the top chambers of the heart. AF occurs in up to 10% of the population over the age of 60.
- Trial name
- NCT00678340
- Testing
- WACA and PVI, PVAC
- Where
- United Kingdom
- Volunteers
- 178 people
- Sponsor
- Pier Lambiase
PICC, Central Venous Catheter
Complications Associated With Central Venous Access in the NSICU: PICC vs CVC
The goal of this study is to determine whether Peripherally Inserted Central Catheter or Centrally Inserted Venous Catheters have lower complication rates in the Neuroscience Intensive Care Unit.
- Conditions
- PICC, Central Venous Catheter, Central Line, Neuro ICU
- Trial name
- NSPVC (NCT02314520)
- Testing
- peripherally inserted central catheter, centrally inserted central catheter
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- Milton S. Hershey Medical Center
Deep Venous Thrombosis
Catheter-Related Early Thromboprophylaxis With Enoxaparin (CRETE) Trial
The purpose of this phase 2a, multi-center, randomized controlled study, is to explore the efficacy of early prophylaxis against catheter-associated deep venous thrombosis (CADVT) in critically ill children.
- Trial name
- CRETE (NCT03003390)
- Testing
- Enoxaparin
- Where
- 6 sites in United States
- Volunteers
- 51 people
- Sponsor
- Yale University
Thrombopenia, Central Venous Catheter Placement
Platelet Kinetics After Platelet Transfusion for the Placement of a Central Venous Catheter
PLATCAT study's purpose is to evaluate platelet kinetics after platelet transfusion
- Trial name
- PLATCAT (NCT02906878)
- Testing
- Platelets transfusion
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Angers
Central Venous Catheter, Catheter-Related Bloodstream Infection (CRBSI) Nos
Access in Dialysis for Better Outcomes in Patient Therapy
This is a prospective, multi-center health economic study in Canada. Participants will be randomly assigned to receive either the study or control dialysis catheter.
- Trial name
- ADOPT (NCT03109574)
- Testing
- BioFlo DuraMax Chronic Hemodialysis Catheter, Standard of Care Catheter
- Where
- 3 sites in Canada
- Volunteers
- 92 people
- Sponsor
- William Osler Health System
Central Venous Catheters
Facilitating Needle Alignment With Aiming Method
Although ultrasound-guided catheterization of the subclavian vein is becoming standard procedure in anesthetic practice, failure to align the needle and the transducer still can lead to possibly complications.
- Trial name
- NCT03778437
- Testing
- subclavian vein catheterization, landmark techniques, Ultrasound-guided plus needle guide techniques
- Where
- China
- Volunteers
- 474 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Central Venous Catheter Exit Site Infection, Central Venous Catheter Related Bloodstream Infection
A New Securement Method for External Tunneled Central Venous Access Devices (CVAD)
An external tunneled central venous access device (CVAD) is a small plastic tube that is tunneled under the skin into a major vein for long-term use (Figure 1).
- Trial name
- NCT04462861
- Testing
- Central venous access device (CVAD) Snuggie Securement Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Colorado, Denver
Central Venous Cather Position
Assessing Validity of M-Mode Time-to-Turbulence "T2T" Echo Use to Confirm CVC Tip Position
Using an ultrasound echocardiography , we will measure the time to turbulance "T2T" from injecting saline into the central venous catheter CVC to the appeareance of turbulance on the screen using an MMode.
- Trial name
- NCT03058445
- Testing
- Echocardiography, CVC
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- South Tyneside and Sunderland NHS Foundation Trust
Insertion Depth of Central Venous Catheter
The Practical Use of Transthoracic Echocardiography for Obtaining an Optimal Depth of Internal Jugular Venous Catheters in Infants
To test if transthoracic echocardiography is useful for correct positioning of central venous catheters in infants with congenital heart disease
- Trial name
- NCT01763229
- Testing
- transthoracic echocardiography
- Volunteers
- 108 people
- Sponsor
- Seoul National University Hospital
Lymphoma, Acute Lymphoblastic Leukemia
A Study of the Safety and Effectiveness of Apixaban in Preventing Blood Clots in Children With Leukemia Who Have a Central Venous Catheter and Are Treated With Asparaginase
The purpose of this study is to compare the effect of a blood thinning drug called Apixaban versus no administration of a blood thinning drug, in preventing blood clots in children with leukemia or lymphoma.
- Trial name
- NCT02369653
- Testing
- Apixaban, No systemic anticoagulant prophylaxis
- Where
- 96 sites in United States, Australia and 10 more
- Volunteers
- 512 people
- Sponsor
- Bristol-Myers Squibb
Vascular Access Complication, Hemodialysis Access Failure
Optimizing Access Surgery In Senior Hemodialysis Patients
The number of elderly hemodialysis patients is growing. Vascular access complications are a major determinant of the quality of life and health care costs for these vulnerable patients.
- Conditions
- Vascular Access Complication, Hemodialysis Access Failure, Dialysis Access Malfunction, Arteriovenous Fistula
- Trial name
- OASIS (NCT05911451)
- Testing
- Arteriovenous fistula creation, Arteriovenous graft placement, Central venous catheter placement
- Where
- 20 sites in Netherlands
- Volunteers
- 166 people
- Sponsor
- Maastricht University Medical Center
Cancer, Hematologic Disorders
Catheter Resistance Monitoring to Predict Catheter-Associated Adverse Events in Children and Adolescents
Catheter occlusion and dysfunction are common complications of central venous access device (CVAD) use in children with cancer and hematologic disorders.
- Trial name
- NCT01737554
- Testing
- Catheter Resistance Monitoring
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- St. Jude Children's Research Hospital
Bacteremia
Prophylactic Antimicrobial Catheter Lock
This is a randomized, double blinded, prospective, multicenter, clinical trial of the use of Heparin versus Gentamicin as a pos-dialysis catheter lock solution.
- Trial name
- ALLOCK (NCT00571259)
- Testing
- Heparin 1000U/mL, 4% Sodium Citrate with Gentamicin 320 mcg/mL
- Where
- United States
- Volunteers
- 303 people
- Sponsor
- Satellite Healthcare
Thrombosis, Venous Thrombosis
Safety and Efficacy Study of Alfimeprase in Subjects With Occluded Catheters
To evaluate the safety profile of alfimeprase as assessed by monitoring of adverse events, serious adverse events and major bleeding events for up to 120 minutes following the instillation of study drug to an occluded central…
- Conditions
- Thrombosis, Venous Thrombosis, Catheter Occlusion
- Trial name
- NCT00322270
- Testing
- Alfimeprase
- Where
- 18 sites in United States
- Sponsor
- ARCA Biopharma, Inc.
Childhood Cancer, Aplastic Anemia
Trial of Two Central Venous Catheter (CVC) Flushing Schemes in Pediatric Hematology and Oncology Patients
The purpose of this study is to determine whether flushing Central Venous Catheters (CVCs) with Normal saline once per week is not inferior to flushing with 10U/ml heparin 3 times per week, in preventing CVC occlusions.
- Conditions
- Childhood Cancer, Aplastic Anemia, Metabolic Disorders
- Trial name
- NCT01343680
- Testing
- Heparin, Normal saline
- Where
- 2 sites in Canada
- Volunteers
- 2 people
- Sponsor
- Alberta Children's Hospital
Nursing Students
Dressing of Tunneled Central Venous Catheter
The purpose of this study was to compare the performance of nursing undergraduates in dressing of tunneled central venous access in the simulator, according to the aid of a preceptorship or an auto-instructional guide.
- Trial name
- NCT01614314
- Testing
- Preceptorship, Auto-instructional guide
- Where
- Brazil
- Volunteers
- 35 people
- Sponsor
- University of Sao Paulo
Intestinal Failure
Video Training Supplementation for Patients Discharged on Home Parental Nutrition
The goal of this clinical trial is to develop an educational video addressing the aseptic techniques to safely handle central catheters for administrating parenteral nutrition at home.
- Trial name
- NCT06169774
- Testing
- Educational video
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Chicago
Dysfunctional Central Venous Access Catheters
A Study of Tenecteplase for Restoration of Function in Dysfunctional Central Venous Catheters
This was a Phase III, randomized, double-blind, placebo-controlled study that was conducted at 24 centers in the United States and Canada.
- Trial name
- TROPICS 1 (NCT00395876)
- Testing
- tenecteplase
- Volunteers
- 100 people
- Sponsor
- Genentech, Inc.