Clinical trials: Central Venous Catheter
Catheter Related Complication
Incidence and Clinical Progression of Asymptomatic PICC-Related Thrombosis in Solid Cancer Patients
In this prospective cohort study, the investigators evaluated the incidence of superficial vein thrombosis, deep vein thrombosis, and fibroblastic sleeve formation in solid cancer patients undergoing chemotherapy.
- Trial name
- NCT05966909
- Testing
- Doppler Ultrasound
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Colorectal Disorders
Does a Central Venous Line Reduce Perioperative Fluid Administration?
'Hypothesis-generating' study to assess whether the presence of a central venous line significantly affects the volumes of fluid infused perioperatively in major elective colorectal surgery
- Trial name
- NCT03985111
- Testing
- Central Venous Catheter
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Barts & The London NHS Trust
Laboratory-confirmed Bloodstream Infection, Central Line-associated Bloodstream Infections
Using Microbial Genomics to Elucidate the Source of Central-line Associated Bloodstream Infections
Central line-associated bloodstream infections (CLABSIs) are the most common healthcare-associated infection in children and are associated with morbidity and mortality.
- Conditions
- Laboratory-confirmed Bloodstream Infection, Central Line-associated Bloodstream Infections, Mucosal Barrier Injury
- Trial name
- NCT02271243
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Boston Children's Hospital
Catheters, Indwelling
Trial of a Novel Fibrinolytic (Alfimeprase) to Clear Thrombosed Vascular Access Devices
This trial is for patients with a central venous catheter (a vascular access device) that is not functioning properly (unable to withdraw blood).
- Trial name
- NCT00073515
- Testing
- Alfimeprase
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- ARCA Biopharma, Inc.
Medical Imaging
Study of the Effectiveness of Central Line Placement Using an Ultraportable Ultrasound Device
The placement of a catheter in a large-caliber vein is sometimes necessary for the administration of treatments or the monitoring of a patient.
- Trial name
- K-T-CO (NCT05692310)
- Testing
- placing a standard central venous line, placement of a central venous line using an ultraportable ultrasound device
- Where
- France
- Volunteers
- 238 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Ischemic Heart Disease, Valvular Heart Disease
Vigileo FloTrac vs Pulmonary Artery Catheter
To study the role of Vigileo monitor using the FloTrac sensor to measure cardiac output using the pulse contour analysis as well as central venous oxygen saturation monitoring as a guide for tissue perfusion.
- Trial name
- NCT00641290
- Testing
- Vigileo FloTrac Sensor
- Where
- Malaysia
- Volunteers
- 60 people
- Sponsor
- Hospital Sultanah Aminah Johor Bahru
Central Venous Catheter Thrombosis, Central Venous Catheter Related Bloodstream Infection
CLiCK in the Critical Care Unit
Insertion of a central venous access device (CVAD) allows clinicians to easily access the circulation of a patient to administer life-saving interventions.
- Conditions
- Central Venous Catheter Thrombosis, Central Venous Catheter Related Bloodstream Infection, Catheter Complications, Catheter Blockage
- Trial name
- CLiCK (NCT04548713)
- Testing
- 4% EDTA, Saline
- Where
- 6 sites in Canada
- Volunteers
- 1,449 people
- Sponsor
- Fraser Health
Behavior, Process, Acceptance
Implementation of Ultrasound Guided Central Venous Catheter Confirmation Protocol
The bedside use of ultrasound after central venous catheter (CVCs) insertion has lagged behind other applications in medicine, thus presenting an opportunity for innovative, evidence-based research that will influence clinician…
- Conditions
- Behavior, Process, Acceptance, Inertia of Accommodation
- Trial name
- DRAUP (NCT04324762)
- Testing
- targetted implementation strategies
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Infection
Developing and Maintaining a Central Venous Catheter Registry
It has been estimated that 90% of bloodstream infections associated with catheters, are due to CVCs, and that 500 to 4,000 patients in the United States die annually due to these bloodstream infections.
- Trial name
- NCT01165411
- Where
- United States
- Volunteers
- 4,530 people
- Sponsor
- Lehigh Valley Hospital
Atrial Fibrillation
First Line Radiofrequency Ablation Versus Antiarrhythmic Drugs for Atrial Fibrillation Treatment (The RAAFT Study)
The purpose of this study is to determine whether catheter-based pulmonary vein isolation is superior to antiarrhythmic drugs as first line therapy in patients with symptomatic paroxysmal recurrent atrial fibrillation not…
- Trial name
- RAAFT (NCT00392054)
- Testing
- Pulmonary Vein Isolation performed by Catheter Ablation, Conventional Antiarrhythmic Drug Therapy
- Where
- 16 sites in United States, Canada and 3 more
- Volunteers
- 127 people
- Sponsor
- Population Health Research Institute
Venous Thrombosis
Peripherally Inserted Central Catheter (PICC) Thrombosis: Reverse Taper Versus Non-tapered Catheters
The purpose of this study is to compare two different marketed PICC (peripherally inserted central catheter) designs. Clotting rates, procedural bleeding and ease of catheter insertion will be compared.
- Trial name
- NCT00728819
- Testing
- Tapered PICC, Non-tapered PICC
- Where
- United States
- Volunteers
- 339 people
- Sponsor
- University of Pennsylvania
Nursing Students
Dressing of Tunneled Central Venous Catheter
The purpose of this study was to compare the performance of nursing undergraduates in dressing of tunneled central venous access in the simulator, according to the aid of a preceptorship or an auto-instructional guide.
- Trial name
- NCT01614314
- Testing
- Preceptorship, Auto-instructional guide
- Where
- Brazil
- Volunteers
- 35 people
- Sponsor
- University of Sao Paulo
Surgical Wound
AMBULATE Continued Access Protocol to Evaluate the Cardiva Mid-Bore Venous Vascular Closure System (VVCS)
The objective of the trial is to demonstrate the safety and effectiveness of the Cardiva Mid-Bore Venous Vascular Closure System (VVCS) in sealing femoral venous access sites at the completion of catheter-based procedures…
- Trial name
- NCT03573206
- Testing
- Cardiva Mid-Bore Venous Vascular Closure Device (VVCS)
- Where
- 3 sites in United States
- Volunteers
- 168 people
- Sponsor
- Cardiva Medical, Inc.
Atrial Fibrillation
Feasibility of Ethanolization of Vein of Marshall With Specific Catheter in Atrial Fibrillation Ablation
In patients with persistent AF (PsAF), ablation limited to pulmonary vein (PV) isolation is the most straightforward approach, but results only in 50% of arrhythmia freedom at 1 year follow-up.
- Trial name
- Innov Marshall (NCT05427435)
- Testing
- Marshall ethanolisation
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Bordeaux
Bacterial Infections
Safety and Efficacy Study of Angiotech Central Venous Catheter to Prevent Bacterial Catheter Colonization
The main purpose of this study is to determine if the Angiotech central venous catheter (CVC) is equal in effectiveness to a CVC coated with chlorhexidine and silver sulfadiazine in preventing bacterial catheter colonization.
- Trial name
- NCT00288418
- Testing
- Central Venous Catheter
- Where
- 21 sites in United States
- Volunteers
- 960 people
- Sponsor
- Angiotech Pharmaceuticals
Subclavian Vein Stenosis, Jugular Vein Occlusion
Central Vein Stenosis Due to Dialysis Catheter Insertion in Subclavian Compared to Jugular Vein
Central vein stenosis (CVS) is a well-known complication of central venous catheterization, especially after insertion of temporary hemodialysis catheters (tHDC).
- Trial name
- CITES (NCT04871568)
- Testing
- Temporary central dialysis catheterization
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Skane University Hospital
Central Lines in ICU Patients
Ethanol Lock for Prevention of Central Line-Associated Blood Stream Infections
Vascular access via central venous lines (CVL) is essential to the care of many patients in the intensive care setting. While the value of these lines for the management of critically ill patients is generally accepted, the…
- Trial name
- NCT01344590
- Testing
- Normal Saline, Ethanol 70% pharmaceutical grade
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Virginia
Central Line Complication
Incidence and Risk Factors of Central Line Catheter Related Thrombosis
Central venous catheters are frequently used for monitoring haemodynamic status and rapidly delivering fluid therapy during the peri- and postoperative periods.
- Trial name
- NCT03450785
- Testing
- ultrasound examination
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Hospital
Quality of Life (QOL), Tracheostomy
Feeding Difficulties and Quality of Life in Children With Tracheal Cannula
The over all goal of this observational study is to study if there is an association between the presence of feeding difficulties and self-assessed quality of life in children with tracheal cannula.
- Conditions
- Quality of Life (QOL), Tracheostomy, Children in the Pediatric Intensive Care Unit or General Pediatric Care Unit Requiring a Central Venous Catheter, Feeding Difficulties
- Trial name
- NCT06893458
- Where
- 2 sites in Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska Institutet
Central Venous Catheterization, Exposure to X-Rays
Agitated Saline Versus CXR Confirmation of Central Venous Lines
Central venous lines insertion are common procedures these days. CVL placed under USG guidance have high success rates and low complications even in developing country settings.
- Trial name
- NCT03442790
- Testing
- Agitated Saline Method, chest x-ray
- Volunteers
- 260 people
- Sponsor
- Nepal Mediciti Hospital