Clinical trials: Central Venous Catheters
Dysbiosis, Catheter-Related Infections
Cutaneous Microbiota Evolution in ICU Patients With CVC (ICMc)
Intensive Care Unit (ICU) patients are exposed to catheter-related infections with an important morbidity. Catheter colonization is constant but infection is not. Cutaneous dysbiosis could be the missing link.
- Trial name
- ICMc (NCT06095076)
- Testing
- Skin swabbing, Data collection
- Where
- French Guiana
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cayenne
Catheterization, Peripheral
Peripherally Inserted Central Catheter Insertion Site and Complication Rate in Neonates
This study examines whether there is an association between the PICC insertion site and the complications necessitating PICC removal in neonates admitted to neonatal intensive care unit.
- Trial name
- NCT03474978
- Testing
- Peripherally Inserted Central Venous Cather (PICC)
- Where
- Canada
- Volunteers
- 320 people
- Sponsor
- University of Calgary
Central Venous Catheter
Use of the Skin Glue in the Placement of Central Venous Catheters Port a Catch
The use of glue as a device in the implantation of central venous catheters has recently been introduced into European clinical practice, initially with the aim of blocking bleeding at the point of exit of the PICCs, but at the…
- Trial name
- Port glue cvc (NCT03801811)
- Testing
- Study of the efficacy of using skin glue in the application of Port a cath
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Parma
Infection
Developing and Maintaining a Central Venous Catheter Registry
It has been estimated that 90% of bloodstream infections associated with catheters, are due to CVCs, and that 500 to 4,000 patients in the United States die annually due to these bloodstream infections.
- Trial name
- NCT01165411
- Where
- United States
- Volunteers
- 4,530 people
- Sponsor
- Lehigh Valley Hospital
Central Venous Catheter, Neonates
Less Pain in Neonates During Central Lines Insertion
Central venous access is an imperative measure used in neonates whether being a peri-operative measure for children undergoing cardiac procedures for congenital heart diseases or as a mean of nutrition in neonatal enteral…
- Conditions
- Central Venous Catheter, Neonates, Pain
- Trial name
- NCT03647293
- Testing
- Ultrasound Guided Central Catheter Insertion, Peripherally Inserted Central Catheter
- Volunteers
- 61 people
- Sponsor
- Saint George Hospital
Central Line-associated Bloodstream Infection (CLABSI), Catheter-related Bloodstream Infection
Effect of Vancomycin After Catheter Replacement
Randomized controlled trial of the effect of a single-dose intravenous Vancomycin after catheter replacement for suspected central line-associated bloodstream infection on resolution of infection in critically ill patients.
- Trial name
- VanCat (NCT04856878)
- Testing
- Vancomycin
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Cancer, Central Venous Catheterization
Study of Sodium Bicarbonate in Restoring Blocked Catheters
This is a study looking at the use of sodium bicarbonate to restore the flow of blocked central line devices in patients with blood cancers.
- Trial name
- NCT03348826
- Testing
- Sodium Bicarbonate 8.4% Solution for Injection, Alteplase Injectable Solution
- Where
- Canada
- Sponsor
- University Health Network, Toronto
Childhood Cancer, Aplastic Anemia
Trial of Two Central Venous Catheter (CVC) Flushing Schemes in Pediatric Hematology and Oncology Patients
The purpose of this study is to determine whether flushing Central Venous Catheters (CVCs) with Normal saline once per week is not inferior to flushing with 10U/ml heparin 3 times per week, in preventing CVC occlusions.
- Conditions
- Childhood Cancer, Aplastic Anemia, Metabolic Disorders
- Trial name
- NCT01343680
- Testing
- Heparin, Normal saline
- Where
- 2 sites in Canada
- Volunteers
- 2 people
- Sponsor
- Alberta Children's Hospital
Central Venous Catheterization, Exposure to X-Rays
Agitated Saline Versus CXR Confirmation of Central Venous Lines
Central venous lines insertion are common procedures these days. CVL placed under USG guidance have high success rates and low complications even in developing country settings.
- Trial name
- NCT03442790
- Testing
- Agitated Saline Method, chest x-ray
- Volunteers
- 260 people
- Sponsor
- Nepal Mediciti Hospital
Compare Central Line Insertion of Subclavian Vein With Two Different Approaches Using Ultrasound
Comparative Evaluation of Ultrasound Guided Supraclavicular and Infraclavicular Subclavian Venous Catheterizations in Adult Patients Undergoing Major Surgeries
Comparison of two techniques of central venous cannulation of subclavian vein using ultrasound was performed. ultrasound guided central venous cannulation is the standard practice today but its use in subclavian vein is…
- Trial name
- NCT02925715
- Testing
- ultrasound guided central venous cannulation
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Cardiac and Pulmonary Complications. Central Venous Line Insertion. Gastrointestinal Recovery
Trial Comparing Routine Intraoperative Transesophageal Echocardiography During Radical Cystectomy to Standard of Care
This is a prospective randomized controlled trial looking at the utility of intraoperative transesophageal echocardiography (TEE) on clinical outcomes after radical cystectomy.
- Trial name
- NCT03058250
- Testing
- Transesophageal echocardiography
- Volunteers
- 80 people
- Sponsor
- University of Chicago
Bacterial Infections
Safety and Efficacy Study of Angiotech Central Venous Catheter to Prevent Bacterial Catheter Colonization
The main purpose of this study is to determine if the Angiotech central venous catheter (CVC) is equal in effectiveness to a CVC coated with chlorhexidine and silver sulfadiazine in preventing bacterial catheter colonization.
- Trial name
- NCT00288418
- Testing
- Central Venous Catheter
- Where
- 21 sites in United States
- Volunteers
- 960 people
- Sponsor
- Angiotech Pharmaceuticals
Hemodialysis
Prophylactic Antibiotic Treatment in Hemodialysis
The purpose of this study is to assess the efficacy of prophylactic antibiotic treatment on blood stream infections and severe culture negative infections, in patients on newly started hemodialysis(HD), with a central venous…
- Trial name
- PANTHEM (NCT05248620)
- Where
- 7 sites in Denmark
- Volunteers
- 800 people
- Sponsor
- Zealand University Hospital
Diamond Blackfan Anemia
Mobilization of Stem Cells With G-CSF for Collection From Patients With Diamond-Blackfan Anemia
This study will provide information needed to develop more effective treatments for patients with Diamond-Blackfan anemia (DBA). Current treatments include steroids, such as prednisone, and blood transfusions.
- Trial name
- NCT00011505
- Testing
- G-CSF, Leukapheresis
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Central Venous Cather Position
Assessing Validity of M-Mode Time-to-Turbulence "T2T" Echo Use to Confirm CVC Tip Position
Using an ultrasound echocardiography , we will measure the time to turbulance "T2T" from injecting saline into the central venous catheter CVC to the appeareance of turbulance on the screen using an MMode.
- Trial name
- NCT03058445
- Testing
- Echocardiography, CVC
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- South Tyneside and Sunderland NHS Foundation Trust
Other Female Genital, Cancer
Scheduled Triple-lumen Central Venous Catheter Exchange: A Prospective Controlled Randomized Study
CVC Pros and Cons of scheduled Triple-lumen Central Venous Catheter Exchange: A Prospective Controlled Randomized Study
- Trial name
- NCT00250809
- Testing
- Placement of a central venous catheter
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of New Mexico
Central Line Complication
CVAD-Associated Skin Impairment in Allogeneic Stem Cell Transplant Recipients: Dressing vs No-Dressing
Central venous access device (CVAD)-associated skin impairment (CASI) is a common problem in allogeneic hematopoietic stem cell transplant (HSCT) recipients.
- Trial name
- NCT03216824
- Testing
- Dressing, No-Dressing
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of British Columbia
Central Lines in ICU Patients
Ethanol Lock for Prevention of Central Line-Associated Blood Stream Infections
Vascular access via central venous lines (CVL) is essential to the care of many patients in the intensive care setting. While the value of these lines for the management of critically ill patients is generally accepted, the…
- Trial name
- NCT01344590
- Testing
- Normal Saline, Ethanol 70% pharmaceutical grade
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Virginia
Central Venous Access, Long Term Antibiotics
Comparison of Two ECG Guided PICC Insertion Techniques
The aim of our study is to compare two ECG techniques for guiding Peripherally Inserted Central Venous Cather (PICC) in terms of accuracy of the final position of the catheter tip.
- Conditions
- Central Venous Access, Long Term Antibiotics, Chemotherapy, Total Parenteral Nutrition
- Trial name
- NCT04466332
- Testing
- LifeCath-CT PICC easy™ (Vygon), PowerPICC-SOLO® (C.R. Bard)
- Where
- Switzerland
- Volunteers
- 320 people
- Sponsor
- University of Lausanne
SIRS
Infections Related Central Venous Catheters
The purpose of this study is to clarify the relationship between SIRS (Systemic inflammatory response syndrome) and the infection associated with the use of central venous catheters at Critical Care center in National Defense…
- Trial name
- CVL (NCT00554021)
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- National Defense Medical College, Japan