Clinical trials: Cephalalgia
Tinnitus
Management of Acute Tinnitus With Migraine Medications
Tinnitus represents one of the most common and distressing otologic problems, and it causes various somatic and psychological disorders that interfere with the quality of life.
- Trial name
- NCT06799169
- Testing
- Nortriptyline, Topiramate, Paroxetine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Irvine
Chronic Migraine, Headache, Temporomandibular Joint Dysfunction
The Effect of Accompanying Temporomandibular Joint Dysfunction in Patients With Chronic Migraine
The aim of this clinical study to evaluate the effect of temporomandibular joint dysfunction accompanying patients with chronic migraine on pain, quality of life, sleep and functionality.
- Conditions
- Chronic Migraine, Headache, Temporomandibular Joint Dysfunction, Chronic Pain, Quality of Life
- Trial name
- NCT05381129
- Testing
- Detection of Pain, Quality of Life, Sleep and Functioning, Temporomandibular joint dysfunction
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Istanbul University - Cerrahpasa
Post-Dural Puncture Headache
Sphenopalatine Block Versus Greater Occipital Nerve Block in PDPH
Management of postdural puncture headache (PDPH) has always been challenging for anesthesiologists. PDPH not only increases the misery of the patient, but the length of stay and overall cost of treatment in the hospital also…
- Trial name
- NCT05235256
- Testing
- bilateral sphenopalatine ganglion block, bilateral greater occipital nerve block, lidocaine plus dexamethasone
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Refractory Chronic Cluster Headache
Refractory Chronic Cluster Headache: Exploring the Potential of Repetitive Transcranial Magnetic Stimulation
The goal of this clinical trial is to learn if drug ABC works to treat severe asthma in adults. It will also learn about the safety of drug ABC.
- Trial name
- NCT06917144
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Spain
- Volunteers
- 8 people
- Sponsor
- Hospital Universitario La Paz
Medication Overuse Headache
CBT in Patients With Medication Overuse Headache
According to the definition from International Headache Society, medication overuse headache (MOH) is diagnosed when patients takes painkillers for more than 10 or 15 days per month (depending on what kind of painkillers being…
- Trial name
- NCT01754571
- Testing
- Cognitive behavior therapy
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Far Eastern Memorial Hospital
Post-Traumatic Headache
Hypersensitivity to Phosphodiesterase 3 Inhibition in Post-Traumatic Headache
To investigate whether cilostazol (phosphodiesterase 3 inhibitor) induces headache with migraine-like features in people with persistent post-traumatic headache (PTH) attributed to mild traumatic brain injury (mTBI).
- Trial name
- NCT05595993
- Testing
- Cilostazol
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Danish Headache Center
Headache, Migraine, Quality of Life
Effects of Aromatherapy on the Headache and Service Quality Among Nurses Working in Critical Care Nurses Units.
Background: Our pilot study showed that the prevalence of headaches is 43.5% among nurses working in critical care units in a medical center in Taiwan.
- Trial name
- NCT03867864
- Testing
- Necklace with essential oil for the first 4 weeks, Necklace without essential oil for the first 4 weeks, Washout
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Migraine
Comparison of Efficacy Between Combination of Amitriptyline-propranolol and Pizotifen for Migraine Prophylaxis.
The goal of this clinical trial is to compare efficacy and observe common adverse effects of a combination of amitriptyline-propranolol and pizotifen as prophylactic treatments for migraine.
- Trial name
- NCT06158230
- Testing
- Pizotifen, Amitriptyline-propranolol
- Where
- Bangladesh
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Migraine Disorders
Long-Term Safety of Treximet (Sumatriptan/Naproxen Sodium) for Migraine in Adolescents
This study was designed to determine long-term safety of TREXIMET (sumatriptan/naproxen sodium) in adolescents for the acute treatment of migraine.
- Trial name
- NCT00488514
- Testing
- Combination Tablet of Treximet (sumatriptan/naproxen sodium)
- Where
- 77 sites in United States
- Volunteers
- 656 people
- Sponsor
- GlaxoSmithKline
Chronic Daily Headache
Multi-center RCT of IV Ketamine Efficacy and Safety in Chronic Daily Headaches
Chronic daily headaches (CDH) poses a significant burden on patients, healthcare systems and the society. Intravenous (IV) ketamine infusion, an intervention that is widely available and scalable, can treat CDH by reversing…
- Trial name
- KetHead (NCT05306899)
- Testing
- Ketamine, 0.9% Saline
- Where
- 2 sites in Canada
- Volunteers
- 56 people
- Sponsor
- University Health Network, Toronto
Migraine Without Aura
Investigation of Serotonin Receptor Binding in the Migraine Brain Using Positron Emission Tomography
Migraine affects 16% of the world population and is one of the most disabling of all disorders. It is a complex brain disorder characterized primarily by recurrent headache attacks.
- Trial name
- NCT02309606
- Testing
- PET scan with 5-HT receptor ligands
- Where
- Denmark
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Migraines
A Nutritional Intervention for Migraines-2
The purpose of the study is to assess whether, in individuals with migraines, a low-fat, vegan diet improves pain more effectively than a control supplement or a placebo.
- Trial name
- WCCR-MIG2 (NCT01699009)
- Testing
- Plant based diet, an unrestricted diet
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Physicians Committee for Responsible Medicine
Headache Disorders, Secondary, Post-Dural Puncture Headache
Association Between Chronic Headache and Back Pain With Childbirth
This study uses a single questionnaire to evaluate two separate primary outcomes: 1. To identify association between chronic headache in women who have given birth to children as compared to a control group of women who have…
- Conditions
- Headache Disorders, Secondary, Post-Dural Puncture Headache, Migraine Disorders, Back Pain
- Trial name
- NCT04091321
- Where
- United States
- Volunteers
- 1,112 people
- Sponsor
- Stanford University
Migraine
Dietary Intervention for Migraine Relief
The goal of this clinical trial is to evaluate whether a low-glutamate diet can improve migraine symptoms in adults with migraine and to explore possible biological changes associated with dietary improvement.
- Trial name
- NCT07360405
- Testing
- Dietary training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- American University
Ischemic Stroke, Brain Tumor
Confounding Factors in the Detection of Intracranial Hemorrhage With the Infrascanner
The investigators prospectively want to use the Infrascanner in patients with ischemic stroke, patients with brain surgery, patients with brain tumors, patients with intracranial hemorrhage and patients with a normal CT scan of…
- Conditions
- Ischemic Stroke, Brain Tumor, Brain Surgery, Intracranial Hemorrhage
- Trial name
- NCT02809651
- Testing
- Infrascanner
- Where
- Belgium
- Volunteers
- 89 people
- Sponsor
- Ziekenhuis Oost-Limburg
Headache, Tension
The Effect of Aromatherapy Applied to Intensive Care Nurses on Tension-Type Headache
Tension-type headache (TTH) is a common symptom in intensive care nurses. The nurses' quality of life, ve social ve business life are negatively affected by the ache.
- Trial name
- NCT06779786
- Testing
- Group 1 (Aromatherapy Groups):, Group 2 (Aromatherapy Groups):
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bartın Unıversity
Primary Headache Disorders
A Prospective Observational Registry of Primary Headache Patients Treated With Ausanil
This study is an observational study with the primary objective to assess the safety and tolerability of Ausanil in the treatment of primary headache disorders.
- Trial name
- NCT02392273
- Testing
- Ausanil
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VR1 Corporation
Binocular Dysfunction, Vertical Heterophoria
Effects of Prismatic Spectacle Lenses on Symptoms of Dizziness, Headache and Anxiety as Caused by Vertical Heterophoria
The purpose of this study is to demonstrate whether, in patients diagnosed with Vertical Heterophoria, the symptoms of dizziness, headache and / or anxiety are reduced or eliminated when a kind of correction called vertical prism…
- Conditions
- Binocular Dysfunction, Vertical Heterophoria, Vision, Binocular, Vision Disparity
- Trial name
- NCT00785135
- Testing
- Lenses containing prismatic correction, Lenses not containing prismatic correction
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Vision Specialists of Birmingham
Headache
Carbachols Headache-inducing Effect and Changes in Cerebral Blood Flow in Migraine Patients
The purpose of this study is to test if carbachol infusion induces headache in migraine subjects as well as intra- and extra-cerebral vasodilatation.
- Trial name
- NCT00564408
- Testing
- Carbachol
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Danish Headache Center
Migraine Disorders
A Pilot Clinical Trial of a New Neuromodulation Device for Acute Attacks of Migraine in Children and Adolescents
Migraine is a neurological disease characterized by severe and recurrent headaches. Children and adolescents with migraine often present to the emergency department (ED) with acute attacks, where migraine accounts for up to ~30%…
- Trial name
- NCT05102591
- Testing
- Ketorolac, Metoclopramide, Active Remote Electrical Neuromodulation Device
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of Calgary
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