Clinical trials: Cephalalgia
Cluster Headache, Episodic
Exploration of Cluster Headache in a PET-MRI Study
Observational study in PET-MRI using the 5-HT1A agonist PET radiotracer [18F]F13640.
- Trial name
- F13640-AVF (NCT05084469)
- Testing
- PET-MRI in pain-free remission period
- Volunteers
- 12 people
- Sponsor
- Hospices Civils de Lyon
Migraine
A Study to Evaluate the Long-Term Safety of M207 in the Acute Treatment of Migraine
This is an open-label, twelve-month safety study. There is a screening period followed by a run-in period to record migraine activity.
- Trial name
- ADAM (NCT03282227)
- Testing
- M207 Microneedle System
- Where
- 31 sites in United States
- Volunteers
- 342 people
- Sponsor
- Zosano Pharma Corporation
Headache
Cervical Stabilization Training on Individuals With Headache
Headache is a common health problem. The most common headaches worldwide are migraine, tension-type headache (TTH), and cervicogenic headache (CGH).
- Trial name
- NCT05839496
- Testing
- Cervical stabilization exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Gazi University
Occipital Neuralgia, Headache
Ultrasound Guided Platelet Rich Plasma Injections for Post Traumatic Greater Occipital Neuralgia
This study is a randomized controlled trial, assessing the effect of a single platelet rich plasma (PRP) injection in post traumatic (concussive) greater occipital neuralgia.
- Trial name
- NCT04051203
- Testing
- Autologous Platelet Rich Plasma Injection, Depo-Medrol and lidocaine, Normal Saline
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Migraine
Cognitive Side Effects of Commonly Prescribed Medications in Pediatric Migraine
The purpose of this study is to determine if there are significant differences in the side effects related to memory, repetition and recall among these three drugs when used in a pediatric population.
- Trial name
- NCT00777218
- Testing
- propranolol, zonisamide, topiramate
- Where
- United States
- Sponsor
- University of South Alabama
Migraine
Physiopathology, Diagnosis and Therapy of Primary Cephalalgia and Adaptive Disorders
The main aim of the present pilot study is to prove the possibility to use the Nitroglycerin (NTG) model to describe the pathophysiology of headache using task-free advanced Magnetic Resonance Imaging (MRI) techniques, in order…
- Trial name
- NCT04696510
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Chronic Cluster Headache
A 1-year Trial to Inform About Long-term Exposure to Eptinezumab in Participants With Chronic Cluster Headache (cCH)
The main goal of this trial is to inform about long-term safety and tolerability of eptinezumab in participants with chronic cluster headache.
- Trial name
- CHRONICLE (NCT05064397)
- Testing
- Eptinezumab
- Where
- 31 sites in United States, Denmark and 7 more
- Volunteers
- 131 people
- Sponsor
- H. Lundbeck A/S
Headache Disorders
Smartphone Use Restriction as Treatment of Primary Headache
The goal of this clinical trial is to study smartphone use restriction as a treatment modality in patients of primary headache. The main question[s] it aims to answer are: 1.
- Trial name
- NCT06041997
- Testing
- Smartphone restriction
- Where
- India
- Volunteers
- 60 people
- Sponsor
- All India Institute of Medical Sciences
Migraine With Aura
Brainstem Grey Matter and Cerebral Autoregulation in Migraine With Aura.
Migraine with aura (MA) is an independent risk factor for stroke and is associated with silent brain infracts and T2 white matter hyperintensities on MRI.
- Trial name
- MINOTAURE (NCT02708797)
- Testing
- Magnetic resonance imaging, Transcranial Doppler
- Where
- France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Migraine, Migraine With Aura
Oxygenation and Perfusion in Patients With Acute Migraine Attacks
The aim of the study is to retrospectively evaluate brain perfusion and oxygenation in acute migraine attacks. Magnetic resonance perfusion and susceptibility weighted imaging are the technics to measure perfusion and oxygenation…
- Conditions
- Migraine, Migraine With Aura, Migraine; Status
- Trial name
- OPAMA (NCT03536936)
- Volunteers
- 1,000 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pain, Headache
The Association Between Pain Catastrophizing Scale Score and Postspinal Headache
This study is aimed to elucidate the association between Pain Catastrophizing Scale Score and Postspinal Headache in Patients Underwent Cesarean Section With Spinal Anesthesia.
- Trial name
- NCT02727244
- Testing
- urgent or elective cesarean section
- Volunteers
- 300 people
- Sponsor
- Tokat Gaziosmanpasa University
Chronic Daily Headache
Atkins Diet for Difficult-to-Control Headaches in Teenagers
This is a 3-month pilot study of 10 adolescents with chronic daily headache. Teens will be placed on a modified Atkins diet and followed with 2 subsequent visits to assess for headache improvement.
- Trial name
- NCT00181064
- Testing
- Modified Atkins diet
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Johns Hopkins University
Coronary Artery Disease, Migraine
A Proteomic Analysis for Understanding the Link Between Migraine and Cardiovascular Disease
This is a multicenter, prospective observational study. Will be collecting data from 90 consecutive patients (aged 25- 60 years ) with and without migraine admitted at our Hospital.
- Conditions
- Coronary Artery Disease, Migraine, Cardiovascular Diseases
- Trial name
- PMCD (NCT06372509)
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Centro Cardiologico Monzino
Post-Traumatic Headache Chronic Without Intractable Headache
Nutrition for Post-Traumatic Headache
The purpose of this multi-site study is to evaluate the efficacy of a high omega-3/low omega-6 dietary intervention (the H3-L6 Diet) vs.
- Trial name
- NCT03272399
- Testing
- Diet/nutrition intervention
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Uniformed Services University of the Health Sciences
Chronic Migraine Headache
Low-Intensity Focused Ultrasound Targeting the Dorsolateral Prefrontal Cortex for Preventive Treatment of Chronic Migraine
Chronic migraine is a disabling neurological disorder characterized by frequent headache attacks and significant impairment of quality of life.
- Trial name
- NCT07857109
- Testing
- Low-Intensity Focused Ultrasound Stimulation
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Chinese PLA General Hospital
Migraine, Patent Foramen Ovale
GORE® CARDIOFORM Septal Occluder Migraine Clinical Study
Multi-center, prospective, randomized, placebo- and sham-controlled study to evaluate the GORE® CARDIOFORM Septal Occluder for migraine headache relief
- Conditions
- Migraine, Patent Foramen Ovale, PFO - Patent Foramen Ovale
- Trial name
- RELIEF (NCT04100135)
- Testing
- Actual device PFO closure, Thienopyridine (clopidogrel or prasugrel)
- Where
- 15 sites in United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- W.L.Gore & Associates
Neck Pain, Ankle Injuries
Acupuncture for Pain Control in the Emergency Department
Acupuncture is widely used for managing acute and chronic pain conditions. In the context of an emergency department (ED), patients often present with non-emergent acute pain symptoms.
- Conditions
- Neck Pain, Ankle Injuries, Headache Disorders, Primary
- Trial name
- NCT02013908
- Testing
- Acupuncture plus standard ED management, Standard ED management alone
- Where
- South Korea
- Volunteers
- 17 people
- Sponsor
- Korean Medicine Hospital of Pusan National University
Headache
S100B in the Care of Non-traumatic Headaches in the Emergency Department
The main objective of this pilot study is to make a first assessment of the discriminating ability of a dosage of S100B protein for differential diagnosis between primary headaches and secondary headaches.
- Trial name
- S100B-Céph (NCT02683304)
- Testing
- Plasma S100B levels at inclusion, Magnetic resonance imaging
- Where
- France
- Volunteers
- 81 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Post-Dural Puncture Headache
Two Fluid Strategies for Prevention of Post-dural Puncture Headache
Postdural puncture headache (PDPH) is a common complication after cesarean delivery (CD). The role of peri-operative fluid therapy in prophylaxis against PDPH is unclear.
- Trial name
- NCT03475784
- Testing
- Restrictive fluid therapy, Liberal fluid therapy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Arthritis, Tendonitis
Prospective Analgesic Compound Efficacy (PACE) Study
A 24-week observational prospective study on the efficacy of topical non-steroidal anti-inflammatory drugs for the relief of pain.
- Conditions
- Arthritis, Tendonitis, Gout, Radiculopathy
- Trial name
- PACE (NCT02403687)
- Testing
- baclofen 2%, Bupivacaine hydrochloride 1%, Cyclobenzaprine hydrochloride 2%
- Volunteers
- 300 people
- Sponsor
- Express Specialty Pharmacy
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